When it comes to cell entry, being average has its advantages
When it comes to gaining entry into cells, size matters. A team from Brown University and the Max Planck Institute for Metals Research has created a model that explains how viruses and other bioparticles slip inside cells without a special protein coating called clathrin. The secret, it seems, is to be average. Mid-sized nanomaterials ?about 27 to 30 nanometers in diameter, or about 1,000...Experimental vaccine protects lab animals against several strains of H5N1
Nations are preparing to stockpile vaccines against H5N1, the strain of influenza virus that experts fear could cause the next flu pandemic. But will these vaccines remain effective as the virus mutates? Researchers present good news in the July 15 issue of The Journal of Infectious Diseases, now available online. Elena Govorkova, MD, PhD, Robert G. Webster, PhD, and coworkers at St. Jude...Several minute intermediate stage in virus-cell fusion discovered; opportunity for drug development
To ignite a life-threatening infection in the body, a virus such as HIV invades body cells by first merging, or fusing, with the cell's outer membrane. Once inside the cell, the invading microbe's genetic material takes over, turning the 'host' cell into a factory to produce more copies of the virus, which then spill out to invade other cells in the body. Scientists had assumed that once a...Aloe vera coating may prolong freshness, safety of fruits and vegetables
gel is best known for its therapeutic effect on burned or irritated skin, but in the future you could be eating the gel as a healthful additive to your fruits and veggies. Researchers in Spain say they have developed a gel from the tropical plant that can be used as an edible coating to prolong the quality and safety of fresh produce. The gel, which does not appear to affect fo...Resveratrol prolongs lifespan and delays onset of aging-related traits in a short-lived vertebrate
By studying a particularly short-lived fish species, researchers have been able to show that a natural compound previously shown to extend lifespan in non-vertebrate organisms can also do so in at least one vertebrate species. The findings, reported by Alessandro Cellerino of the Scuola Normale Superiore, Pisa, and colleagues, support the potential utility of the compound in human aging research....Customers Rate Epic as Best Overall Vendor in Healthcare for Seventh Consecutive Time
MADISON, WI - KLAS Enterprises, a research and consulting firm based in Draper, UT, named Epic Systems Corporation Best Overall Vendor in its Top 20 Year-end Report Card. The study, which included 200 vendors, was based on a confidential survey of CIOs, executives, managers, and clinicians representing over 4,000 healthcare facilities. KLAS specializes in monitoring and reporting the...Small-Molecule Quantitation Using Automated Single-Shot Averaging MALDI-TOF Mass Spectrometry
Traditionally, MALDI-TOF mass spectrometry has been used very little for quantitative studies. Analysts have usually assumed that potential differences in ionization efficiency between analyte and internal standards and an inherent heterogeneity of the sample spot would limit MALDI-TOF mass spectrometry as a quantitative technique. In addition...Analysis of a Verapamil Microsomal Incubation using Metabolite ID and Mass FrontierTM
The characterization of a drugs metabolites plays a crucial role throughout its development. In the early discovery p...Hike in drug licence fee could hit several SSI units in TN
The recent hike in the drug manufacturing licence fee and product inspection fee could badly hit several small scale drug units in Tamil Nadu. According to industry sources here, the steep hike in the licensing fees has come at a time when the industry in the state is reeling under tight market conditions with many companies on the brink of closure. // The drug manufacturing licence...Beverage protect against bladder cancer
According to a study in the Community Health, coffee may protect against the development of bladder cancer, especially in smokers..Researchers analysed data from all new and already diagnosed cases of bladder cancer over a 1 year period from 10 general hospitals.// All patients and over 500 cases supplied details of their employment history, tobacco use, including exposure to environmenta...Hydration requirements can be fulfilled with beverages too
We have told for a long time now a lot of health experts that to staywell-hydrated one needs to drink a lot of water. It has been advised we shoulddrink at least eight 8-ounce glasses of water per day to make sure we areadequately hydrated. Researchers from Center for Human Nutrition at theUniversity of Nebraska have now reported that drinking other beverages will alsohelp us keep ourse...Benefits Of The Worlds Most Widely Used Beverage
Type-II diabetes, the sixth leading cause of death in the United States, is linked to obesity and lack of exercise. It causes the // body to lose its ability to use insulin properly to metabolize food, especially sugar. Type-I or juvenile diabetes is a different disease caused by the destruction of key pancreatic cells. In a recent study of 14,600 people, it was found that women who dow...Overactive brain regions can lead to anorexia nervosa
Over activity of a chemical in a specific region of the brain may be responsible// for the eating disorder of anorexia nervosa. Anorexia nervosa is an eating disorder characterized by purposeful weight loss that is often brought about by the patient. Poor self-image often causes the disorder that may result in malnutrition of varying degrees, with endocrine and metabolic changes happen...Genomic Microarray Comprehensive Coverage
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Genomic Microarray Panel: Constitutional and Comprehensive Coverage
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...