VARI researcher chosen for highly competitive Scholar-in-Training Award
...tumors. VARI researchers tested the effect of the BHD gene in two different tubules that are part of the filtration system of the kidney and found initial evidence that one of the tubules may be where BHD originates. In addition to Chen, five other VARI resea...Female Hormones Deter Salt-Sensitive Hypertension
...rives up blood pressure as the body tries to force the kidneys to get rid of excess salt. Endothelin B (ETB) receptors, found in the blood vessels and tubules of the kidney, are thought to act as gatekeepers, deciding how much salt the body should excrete. "We know from other studies we have done that thi...CSHL scientists discover link between control of chromosome duplication and segregation
...e, position themselves at opposite ends of the dividing cell. Each centrosome serves as an anchor for a spindle, a complex structure of filament-like tubules that radiates out from each centrosome and connects with special sites called centromeres on the chromosomes. By pulling on the chromosomes, the spin...New study examines the validity of epo testing
...tment of Anesthesiology, Mayo Clinic, wrote that the physiological background for testing Epo in urine is complex and the handling of Epo by the renal tubules is poorly understood. The high number of false negative results found in the study implies a risk that athletes who use rHuEpo will avoid detection an...New treatment option studied for bladder cancer
...ive. The most effective drug we have cant be used in some patients, Dr. Coleman says. Bladder cancer, the sixth most common cancer, often obstructs tubules that connect the kidney to the bladder, says Dr. Coleman. While the cancer typically doesnt spread upward, tubule blockage damages the kidneys. Additi...Infertility is Seen in Men With SLE
...verity of sperm abnormalities, suggesting severe damage to the seminiferous tubules (the tiny tubes in which sperm are produced) in SLE. Follicle-stimulat...FSH) is a major marker of the function of the cells lining the seminiferous tubules and its higher levels in the group 2 SLE patients suggest testicular damage...Chinese Medicinal Compound Stops Formation of Cysts in Polycystic Kidney
...normal kidney development, cells lining the kidney tubules continue growing and dividing until they receive a... to stop, the cells lining the fully-formed kidney tubules keep right on subdividing and growing. The result ...ed growth: uncontrolled growth of cells lining the tubules and the formation of large cysts in the kidneys. ...Triptolide: A Potential Drug for Polycystic Kidney Disease
...tional Academy of Sciences. Over 12 million people worldwide suffer from PKD, a genetic disorder that causes uncontrolled growth of cells lining tubules in the kidneys, and results in the formation of many, large fluid-filled cysts in the kidneys. “Unfortunately, aside from kidney transplantation...Prestigious Wilson Award Goes To Yale Cell Biologist Joel Rosenbaum
...emote. Few had paid attention to the fact that the cells forming the kidney tubules each had a single non-motile “primary” cilium pointing toward the center of...George Witman at University of Massachusetts Medical School examined kidney tubules of the PKD mutant mouse with the scanning electron microscope, they found t...Two Chemical Compounds Restore Healthy Glucose Levels In Obese Mice
...was a hypothesis that the key to the obesity-diabetes connection might be found in the endoplasmic reticulum, or ER - a system of folded membranes and tubules in the cytoplasm of cells where proteins and lipids are manufactured, processed, and shipped around the cell. When unusual demands - such as excess fa...Freezing Kidney Cancer: Hot Treatment Should Be New Gold Standard for Destroying Small Tumors
...ost common cancer in men and the tenth in women. The most common type of kidney cancer is renal cell carcinoma, which forms in the lining of the renal tubules in the kidney that filter the blood and produce urine. Approximately 85 percent of kidney tumors are renal cell carcinomas. More than 32,000 Amer...Retinol Binding Protein EIA Vitamin Assays 030-6110 RBP Bone and Minearl Metabolism
Description:...e the vitamin has been deliverd to the target cells. The free RBP molecule is then rapidly filtered at the glomerulus and catabolized in the renal tubules after resorption by the proximal tubular cells (like other small molecules e.g. -2 Microglobulin). In kidney disease with prevailing tubular chang...Nephrogenic Diabetes Insipidus
...urogenic diabetes insipidus . ... The Diabetes Insipidus Foundation, Inc. ... Nephrogenic diabetes insipidus occurs when the kidney tubules ... Nephrogenic diabetes ... Most commonly, nephrogenic diabetes insipidus develops because ... Support information for Nephrogenic D...Researchers may have found why women have an edge on salt-sensitive hypertension
... on how these endothelin A, or ETA, receptors work in the blood vessels and tubules of the kidney. They also may help explain the swelling that occurs in some ...ically determine what different receptor subtypes are doing in the kidney's tubules and vasculature while colleagues at the University of Edinburgh in Scotland...Protein 'tubules' free avian flu virus from immune recognition
...vian influenza virus strain called H5N1 forms tiny tubules in which it "hides" the pieces of double-stranded ...r portions of the protein NS1 combine to form tiny tubules where double-stranded RNA is hidden from the immun...r factor binding sites found on the surface of the tubules also play a role in fooling the immune system. ...Link possible between pet food contamination and baby formula contamination
...wo compounds form a virtually insoluble complex. This complex forms in the tubules of the kidney, blocking urine flow and causing renal failure. The research...s soluble in acid, suggesting that acidification of the urine in the distal tubules of the kidney may be a reasonable treatment option. ...Bacterial slime helps cause serious disease
...finding is a step forward in our understanding of Leptospirosis. We now need to study the mechanism of biofilm formation in both fresh water and renal tubules in animal kidneys, said Professor Picardeau. We hope our research will lead to the identification of new strategies to diagnose and prevent this negle...Genetic tug of war determines sexual differentiation
...o the formation of specialized cells known as Sertoli cells, which then spur the cascade of events leading to the formation of the future seminiferous tubules of the adult testis," she continued. "Once the testes are formed, they start producing testosterone, which commits the whole animal to male developmen...'Underground' tunnels discovered as means for communication between immune system cells
...hat intercellular communication is much more complicated. While it would be fascinating to see this interplay inside living tissue, detecting the tiny tubules in such a complex environment may be nearly impossible with current technology. ...Glossary for The BioPharm Guide to Fermentation and Cell Culture
...fense against foreign nucleic acids. endoplasmic reticulum A highly specialized and complex network of branching, interconnecting tubules (surrounded by membranes) found in the cytoplasm of most animal and plant cells. The rough endoplasmic reticulum is where ribosome...An Image-Based Assay of Endothelial Cell Tube Formation as a Model of Angiogenesis
...l cells ability to form distinct blood-vessel-like tubules in an extracellular matrix (BD Matrigel Matrix) wh...escence microscopy. Although quantification of the tubules can be performed by manual tracing, this method pr...total length of the tubules, the total area of the tubules and the total number of segments. The software all...