Old drug, new tricks: Prospects for slashing the impact of malaria
A dramatic reduction in the impact of malaria is in prospect with a clinical drug trial to begin in Papua New Guinea early next year. Success in the trial would open the way to relief in the 10% of humanity infected with this debilitating and often fatal disease - over 500,000,000 people. The Walter and Eliza Hall Institute of Medical Research is collaborating with the Papua New Guinea In...Key To Stem Cell Transplant Success Is Tricking Immune System
A new study reveals critical molecular events in the origin of fat cells. The findings are central to understanding chronic diseases, such as obesity and diabetes, as fat cells produce hormones critical for metabolic control, the researchers said. The study finds that a hormonal cocktail routinely used in the lab induces a key genetic switch in the transition from fat-cell precursors to fu...Dangerous tricksters: Some bacterie use immune cells to reproduce
Macrophages are effective weapons used by our immune system to absorb and digest pathogenic intruders. Some bacteria, however, can subvert this defence mechanism and even multiply within the macrophages. Cell biologists at the University of Bonn have revealed such a strategy in a recently publication in the journal 'Traffic' (Vol. 6, No. 8, August 2005, pp.635-653). Their findings reveal that the...Researchers use 'trickery' to create immune response against melanoma
Ground-breaking results from researchers at Harvard Medical School and Massachusetts Institute of Technology (MIT), USA, disclosed at the 13th European Cancer Conference (ECCO) have shown for the first time that targeted drug delivery is possible using nanoparticle-apatamer conjugates. Nucleic acid ligands (referred to as aptamers) are short DNA or RNA fragments that can bind to target an...Sea coral's trick helps scientists tag proteins
The glow emitted by a variety of sea coral helped Russian scientists harness the protein that generates the light to create a tiny fluorescent tag that responds to visible light. The two-color tag should help researchers follow individual proteins as they dart around inside living cells. Under a microscope, the two-color tag--called Dendra because it is derived from the sea coral Dendronep...Japan's pharma mergers will trickle to the Midwest
In past columns, we have talked about the consolidation of the Japanese pharma industry. The Japanese are actually arriving late to the consolidation party as both American and European companies have been consolidating for years and cont...Illegal business tricks: Can my company do that?
Because I used to be a corporate HR person, people ask me HR questions all the time. One of the most popular forms of question that I get asked is: Can my company actually do that? The answer often is: Well, not legally, but it appears they did anyway. Im not a lawyer. I dont send people off to sue their current or past employer (or at least I havent so far). Life is long. So ma...Tapeworm's Chemical Trick Could Make Drugs More Effective
MADISON, WI - To survive and thrive in a decidedly hostile environment, the lowly tapeworm uses a chemical trick to evade the propulsive nature of its intestinal home. Capitalizing on that tapeworm chemistry, scientists at the University of Wisconsin-Madison believe they may have found a way to slow the transit of drugs through the intestine, making them more effective in their delivery...WTN exclusive interview with Patrick Kennedy, exec. VP, Sony Pictures Digital
Sony's Patrick Kennedy has focused his professional career on business strategy and corporate development issues in the telecom and entertainment fields. Currently, he oversees the day-to-day strategic operations of the an alignment...Researchers trick Alzheimer's Enzyme
According to researchers in Scripps Research Institute, chemists have tricked an enzyme essential in Alzheimer's disease into blocking its own debilitating action.// A team led by Nobel laureate K. Barry Sharpless developed the chemical trick, called "click chemistry," to make a molecule that blocks neurotransmitter destruction caused by the brain enzyme acetylcholinesterase. The destr...Y chromosome uses trick to repair its own genes
Scientists have discovered that the Y chromosome uses a neat trick to repair its most crucial genes, a strategy that apparently helps keep it from rotting away over evolutionary time. The Y chromosome, of course, is best known for supplying the biological signal that makes males rather than females. Some scientists have suggested it might disappear millions of years from now becaus...Fructose is a tricker and not all that sweet!
After sucrose it is the turn of fructose to be blamed for obesity by a study in Florida. The study was conducted in the University of Flroda and the findings point that fructose present in fruits//, honey and other natural sources might be the cause of obesity in subjects. The trick is that Fructose makes beleive that the subject is hungrier than actually being and so the result is that...PHC Doctors Tricked Tribal Women To Undergo Sterilization
Doctors in Jharkhand tricked a tribal woman to undergo sterilization, which has triggered widespread protests from the social organizations//. A woman from an endangered primitive tribe in Jharkhand was made to undergo surgical sterilization by some overzealous doctors, triggering an outcry from social organizations. Shobha Dehri, a resident of Paharia colony in Dumka, ab...Indian Scientist who Enthralls Public With Magic Tricks
Whether he is enthralling people with his magic tricks or debating on the latest advances in microbiology, Professor Gursharan Singh Chhatwal does both with ease //. Chhatwal is considered a brilliant cook and a gifted magician. But the scientist from India has also gained renown for his work against the killer streptococci bacteria. 'It is no problem for me to cook even f...