30 percent RA patients refractory to anti-TNFs achieve disease remission with tocilizumab plus metho

Paris, France, Friday 13 June 2008: Tocilizumab plus methotrexate showed significant clinical improvements in efficacy and safety in patients with moderate to severe rheumatoid arthritis (RA), who had not adequately responded to anti-tumour necrosis factor (anti-TNF) therapy, according to a new st...

ACTEMRA(R) (tocilizumab) Studies to be Featured at the European League Against Rheumatism (EULAR) Congress

...ing the Novel Therapeutic Approaches for RA session. "Efficacy of tocilizumab (TCZ) in Rheumatoid Arthritis (RA): Interim Analysis of Long-term Extension...e 12, 11:45 a.m. - 1:30 p.m. CEST in the Bella Center. "Efficacy of tocilizumab (TCZ) vs Methotrexate (MTX) Monotherapy in Patients with Rheumatoid Arthrit...

New Rheumatoid Arthritis Drug Works for Adults, Children

... But the real test for tocilizumab lies in head-to-head drug trials, expert says ..., according to the results of two new studies. tocilizumab works by blocking the interleukin-6 receptor. Inte...t convinced, especially for adults, that comparing tocilizumab to a placebo -- as was done in these studies -- pr...

Humanized Antibody Therapy Found Highly Effective in Easing RA Symptoms

...tients with rheumatoid arthritis (RA), who receive tocilizumab in addition to ongoing methotrexate therapy , show...arcelona. These data show the potential of tocilizumab as a novel and attractive approach to treating RA....rved across both 4mg/kg and 8mg/kg doses show that tocilizumab offers significant promise to patients with modera...

New Drug for Rheumatoid Arthritis Looks Promising.

...limumab (Humira), in combination with methotrexate, have significant anti-inflammatory and joint-protecting activity. Abatacept, rituximab, and tocilizumab all achieved better clinical results in combination with methotrexate than when used as monotherapy. Currently available drugs that target a pr...

tocilizumab in Medical Technology

New Data Confirms Significant Improvement of Disease Signs and Symptoms in Patients with Rheumatoid Arthritis

...mb1106">www.roche.com/med_events_mb1106 References: (1) TOWARD refers to tocilizumab in cOmbination With traditional DMARD therapy (2) The ACR response is a sta... significant improvement in a patient's condition. (3) OPTION refers to the tocilizumab Pivotal Trial in Methotrexate Inadequate respONders Roche Group Media Off...

Three New Drugs Mark New Era in Rheumatoid Arthritis Treatment

...much more pronounced than in patients given placebo instead of abatacept. tocilizumab targets interleukin-6, which is known to activate many cell populations. As with abatacept, combining tocilizumab with methotrexate reduced RA symptoms (in a phase II trial) by 50% in more ...

tocilizumab in Biological Technology

ACTEMRA(R) (tocilizumab) Studies to be Featured at American College of Rheumatology Annual Scientific Meeting

...pm - 3:15 pm PDT, Room 307 [Oral Presentation during the RA Treatment: Biologic Efficacy RCT's session], "The AMBITION Study: Superiority of tocilizumab vs. Methotrexate Monotherapy in Patients with Rheumatoid Arthritis" (Presenter: Graeme Jones, M.D.) -- October 28, 3:15 pm - 3:30 pm PDT, ...