30 percent RA patients refractory to anti-TNFs achieve disease remission with tocilizumab plus metho
Paris, France, Friday 13 June 2008: Tocilizumab plus methotrexate showed significant clinical improvements in efficacy and safety in patients with moderate to severe rheumatoid arthritis (RA), who had not adequately responded to anti-tumour necrosis factor (anti-TNF) therapy, according to a new st...New Rheumatoid Arthritis Drug Works for Adults, Children
... But the real test for tocilizumab lies in head-to-head drug trials, expert says ..., according to the results of two new studies. tocilizumab works by blocking the interleukin-6 receptor. Inte...t convinced, especially for adults, that comparing tocilizumab to a placebo -- as was done in these studies -- pr...Humanized Antibody Therapy Found Highly Effective in Easing RA Symptoms
...tients with rheumatoid arthritis (RA), who receive tocilizumab in addition to ongoing methotrexate therapy , show...arcelona. These data show the potential of tocilizumab as a novel and attractive approach to treating RA....rved across both 4mg/kg and 8mg/kg doses show that tocilizumab offers significant promise to patients with modera...New Drug for Rheumatoid Arthritis Looks Promising.
...limumab (Humira), in combination with methotrexate, have significant anti-inflammatory and joint-protecting activity. Abatacept, rituximab, and tocilizumab all achieved better clinical results in combination with methotrexate than when used as monotherapy. Currently available drugs that target a pr...Three New Drugs Mark New Era in Rheumatoid Arthritis Treatment
...much more pronounced than in patients given placebo instead of abatacept. tocilizumab targets interleukin-6, which is known to activate many cell populations. As with abatacept, combining tocilizumab with methotrexate reduced RA symptoms (in a phase II trial) by 50% in more ...