Activation of thermoreceptors mediates raw garlic's burning pungency
The worldwide popularity of garlic as a food ingredient and its therapeutic stature in folklore both stem in part from the distinctive pungency associated with its raw, uncooked state. Researchers this week report that this pungency, manifested as a characteristic mixture of burning and prickling sensations and flavor, can be ascribed largely to the effects of a particular compound and its abilit...Molecular thermometers on skin cells detect heat and camphor
The human brain is like a general in a bunker. Floating in its bubble of cerebrospinal fluid, it has no direct window to the outside world, so the only way for the brain to observe, comprehend, and order the body into action is to rely on information it receives. This information comes to it through a sophisticated system of sensory neurons that connect the brain to organs like the eye, ear, nose...Study Finds Moderate Hypothermia A Safe Treatment For Traumatic Brain Injury In Kids
A first-of-its-kind multi-center trial has shown that cooling the body can have positive affects on children who suffered traumatic brain injury. The study's lead investigator, Children's Hospital of Pittsburgh neurosurgeon P. David Adelson, MD, and fellow researchers determined that induced moderate hypothermia initiated after severe traumatic brain injury (TBI) is a safe therapeutic inte...Research reveals inner workings of immune system 'thermostat'
When bacteria, viruses or parasites attack, immune system cells unleash the soldiers. These "hot" protein compounds kill invaders ?but also trigger inflammation, which, if unchecked, can destroy tissue, induce shock and kill the host. So immune system cells let loose another protein compound to cool down the immune response. Precisely how this immune system "thermostat" operates is unclea...Heart has enough oxygen to survive hypothermia, CPR crucial
Researchers from Norway may have ruled out insufficient oxygen supply to the heart as the critical variable in whether a mammal's heart survives while in a hypothermic state. Writing in the July issue of the American Journal of Physiology-Heart and Circulatory Physiology, researchers found no significant difference in the amount of oxygen available to the heart between rats exposed to one...Mastercycler ep gradient S thermal cycler from Eppendorf North America
Description:To keep pace with these technological advances, the challenges of tomorrow must b...Thermo Sequenase Dye Primer Manual Cycle Sequencing Kit from USB Corp.
Description:The Thermo Sequenase Dye Primer Manual Cycle Sequencing Kit is designed to be used with fluorescent dye-labeled primers and high-resolution fluorescence scanners. Sequencing reactions involve a termination step followed by standard slab gel electrophoresis and scanning of the gel to detect fluorescently tagged sequencing products. The kit components have been optimized for sequencing direc...Applied Biosystems 2720 Thermal Cycler from Applied Biosystems
Description:This personal-sized Thermal Cycler is the ideal instrument for budget-conscious labs that want to perform a full range of PCR applications. The A...Finnigan Pocket Surveyor from Thermo Scientific
Description:The new Finnigan Pocket Surveyor software provides local instrument control for new and existing Finnigan Surveyor HPLC Systems. The software operates on a handheld computer running the popular Windows Pocket PC 2002 O/S and offers chromatographers the ability to connect directly to their Surveyor quaternary gradient pump and/or variable wavelength detector....DSQ II Single Quadrupole GC/MS from Thermo Scientific
Description:The DSQ II (Dual-Stage Quadrupole) Thermo Scientific (Part of Thermo Fisher Scientific) the world leader in analytical instrumentation, introduces the latest product innovation for laboratory GC/MS the DSQ II. Based on the proven reliability and performance platform of Thermo's DSQ and PolarisQ GC/MS systems, the DSQ II incorporates the new DynaMax XR ion detection system and the DuraBrite ion...Effects of Thermal Cycler Well-To-Well Temperature Uniformity on PCR Results
Michelle Cayouette Jane Moores Jason Capodanno Michael Rahilly Stratagene produces consistent PCR results in every well. The RoboCycler systems uniquedesign uses thermal blo...Normalizing cDNA libraries using the EppendorfThermomixer
During many experiments in molecular biology, the individual mRNA expression pattern of a cell is examined in order to investigate the reaction of a cell to exogenous influences such as viral infections or medical treatment. To allow unstable mRNA to be examined more thoroughly, it is converted to cDNA. If all iso...C. therm. Polymerase One-Step RT-PCR System
for one-step RT-PCR amplification of up to 3 kb RNA targets Cat. No. 2 016 338 50 reactions Cat. No. 2 016 346 250 reactions The system contains a unique enzyme blend of C. therm. Polymerase and Taq DNA Polymerase. Note: C. therm. Polymerase prov...C. therm. Polymerase for Reverse Transcription in Two-Step RT-PCR
Polymerase for two-step RT-PCR amplification of up to 4 kb targets C. therm. Polymerase provided by Roche Applied Science is the recombinant form of the DNA polymerase from the thermophilic eubacterium Carboxydothermus hydrogen...Thermal Cycling Profile for Standard PCR
It is very important to denature the template DNA completely. Initial heating of the PCR mixture for 2 minutes at 9495C is enough to completely denature complex genomic DNA so that the primers can anneal to the template as the reaction mix is cooled. If the template DNA is only par...Blood test developed for malignant hyperthermia
Experts have developed a blood test to determine the genetical predisposition for a rare condition// called malignant hyperthermia. Malignant hyperthermia is an inherited disorder that can affect the patient during or after general anesthesia. This condition may be triggered by volatile anesthetics or depolarizing muscle relaxants that have to work together with a genetical predisposit...Whole-body hypothermia reduces risk of death in Encephalopathy in infants
Among infants, hypoxic–ischemic encephalopathy due to acute perinatal asphyxia remains an important cause of neurodevelopmental deficits in childhood//. Infants with moderate encephalopathy have a 10% risk of death, and those who survive have a 30% risk of disabilities. 60% of infants with severe encephalopathy die, and many, if not all, survivors are handicapped. Treatment is current...Learn From a Leader: Smitherman shares a personal story about his battle with drugs
Ontario's health minister made a public confession, during his speech at the Center for Addiction and Mental Health Courage to Come Back, that he had spent precious// five years in the throes of drug addiction. Being perhaps the first cabinet minister to admit that he is also gay, the minister spoke of his suffering and struggle with drugs, which he eventually gave up only due to courage...Heart Has Enough Oxygen to Survive Hypothermia; CPR Crucial
Researchers from Norway may have ruled out insufficient oxygen supply to the heart as the critical variable in whether a mammal’s heart survives while in a hypothermic state.// Writing in the July issue of the American Journal of Physiology-Heart and Circulatory Physiology, researchers found no significant difference in the amount of oxygen available to the heart between rats exposed...Thermal Imaging Shatters Arousal Gender Gap Myth
A new McGill University study that used thermal imaging technology for the first time ever to measure sexual arousal rates has turned the conventional // wisdom that women become aroused more slowly than men on its head. “Comparing sexual arousal between men and women, we see that there is no difference in the amount of time it takes healthy young men and women to reach peak arousal,”...CoolGard 3000 Thermal Regulation System
Description:All Alsius heat exchange catheters connect to the CoolGard 3000 Thermal Regulation System, which achieves and maintains a target temperature input by the user. It remotely senses changes in patient core temperature and automatically adjusts the temperature of the circulating saline within the catheter (0-42C), providing consistent maintenance of temperature. The CoolGard 3000 represents a powerfu...Studies Show Mild Hyperthermia Enhances Antitumor Effects of Alfacell's Onconase
BLOOMFIELD, N.J., March 22, 2007 /PRNewswire-FirstCall/ --Alfacell Corporation today reported that in vitro studies show mildhyperthermia enhances the therapeutic effects of ONCONASE(ranpirnase), the company's lead investigational drugcandidate. In a paper entitled, "Mild hyperthermia predisposes tumor cellsto undergo apoptosis upon treatment with ONCONASE," published inthe Intern...