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telomeres in Medical News

Video: New Online Film Introduces Longevinex Advantage(TM) -- The First Resveratrol-Based Dietary Supplement to Address Both Cellular and Connective Tissue Aging

...ules such as resveratrol. But resveratrol pills have an inherent flaw -- they narrowly address cellular aging, which is characterized by shortening of telomeres (end caps on chromosomes), loss of cellular energy produced in the mitochondria, and progressive accumulation of cellular debris called lipofuscin whi...

Study gives clues to how adrenal cancer forms

...it as the little tip that caps off a shoelace. The telomeres send signals to the cells to let them know it's th...be repaired. Over time, as cells reproduce, the telomeres become shorter and eventually no longer do their j...velop cancer. The mice that also had dysfunctional telomeres were particularly prone to develop the usually ult...

Multivitamins Might Prolong Life

...omosomes, protect chromosomes from damage. Because telomeres shorten slightly when cells divide, researchers sp...ltivitamin use is associated with longer leukocyte telomeres among women," said lead researcher Dr. Honglei Che...In addition, the health effects of slightly longer telomeres are not well-established, Katz said. "In looking a...

RevGenetics Releases Its New Science-Based Telomere Health Supplement Formulation for DNA and Chromosome Health

...pieces of human chromosomes, called telomeres. According to the study, telomeres are simply needed to protect the chromosome from coming undone, as well as ...nformation that cells need every time they divide. When cells divide, these telomeres grow short. When they grow short, they come to a point where they lose thei...

KLRI Releases 3rd Annual Report On Year's Top Longevity Research Findings

... and reverse the effects of aging on memory brain cells and function. telomeres and insulin resistance. telomeres are caps on the end of a cell's chromosomes that help keep chromosomes stab...

First sister study results reinforce the importance of healthy living

...many measures being looked at in the Sister Study. telomeres protect the ends of chromosomes and buffer them ag...tion. Over the course of an individual's lifetime, telomeres shorten, gradually becoming so short that they can...s such as obesity and perceived stress may shorten telomeres and accelerate the aging process. "Together th...

Immune cells from patients with rheumatoid arthritis have prematurely aged chromosomes

... of cell division unless a specialized enzyme replenishes them. Maintaining telomeres is thought to be important for healthy aging and cancer prevention. By t...differently. They found the answer in telomerase, the enzyme that renews telomeres and is necessary to prevent loss of genetic information after repeated cell...

The 2009 Leibniz Prize: Eleven new scientific discoverers

...ar Medicine and Max Planck Research Group on Stem Cell Aging, University of Ulm (2.5 million euros) Karl Lenhard Rudolph's work focuses on telomeres. telomeres are segments of DNA that are found at the ends of linear chromosomes and that become slightly shorter with each cell division. Rudolph has studied thi...

Smoking May Harm the Egg, Embryo

...s and embryos. The study was designed to examine whether cigarette smoke causes oxidative stress, cell death and dysfunction, and the shortening of telomeres (DNA at the ends of chromosomes that protect them from degradation). Two groups of female mice were exposed to cigarette smoke or cigarette smoke cond...

Science Fiction Has Become Reality with Remarkable Anti-Aging Treatment Breakthrough - Turning Back the Biological Clock in Aging

...ll in your body. Each time your cells divide, your telomeres get shorter. You can think of them as a kind of countdown clock. And when your telomeres run down to a critical shortness, cell division st...ess Research Chief Marketing Officer. "The shorter telomeres get the more a person ages. Never before has it be...
telomeres in Medical Technology

A Milestone in Cancer Genetics: deCODE Discovers First Common Genetic Variants Affecting the Risk of Many Types of Cancer

...Shorter telomeres have recently been linked to risk of certain cancers, and telomeres are known to become shorter with the accumulation of environmental insults ...er in individuals with shorter telomeres than long, whereas those with long telomeres are at greater risk of melanoma. Through a more detailed analysis of this r...

Telomerase Presentations at the AACR 2007 Annual Meeting

...LO PARK, Calif.--(BUSINESS WIRE)--Apr 25, 2007 - Geron Corporation (Nasdaq:GERN) today referenced multiple presentations on the role of telomerase and telomeres in cancer at this year's American Association for Cancer Research (AACR) Annual Meeting in Los Angeles. There were approximately 80 presentations on t...
telomeres in Biological News

Tiny roundworm's telomeres help scientists to tease apart different types of aging

The continual and inevitable shortening of telomeres, the protective "caps" at the end of all 46 human chromosomes, has been linked to aging and physical decline. Once they are gone, so are we. But there are more ways than one to grow old. Researchers at Salk Institute for Biological Studies demo...

Telomeres resemble DNA fragile sites

...esearchers at Rockefeller University now show that telomeres have their own weakness. They resemble unstable pa... can stall and go awry. But what keeps our fragile telomeres from falling apart is a protein that ensures the s...in the lab, suggests a striking similarity between telomeres and common fragile sites, parts of the genome wher...

Peter Baumann named Howard Hughes Medical Institute Early Career Scientist

...termine how cells maintain the ends of their chromosomes, called telomeres. telomeres shorten as we get older, and mutations that result in accelerated shortenin...ancer drugs. By understanding how telomere lengthening is regulated and how telomeres are prevented from becoming too short, Dr. Baumann's research team hopes to...

The egg makes sure that sperm don't get too old

...hat measures the age of the cell. The cell stops dividing and dies when the telomeres become too short. The discovery that the egg cell can extend the telomeres of a fertilising sperm cell is important in the development of stem cell th...

UT Southwestern researchers identify gene linked to inherited form of fatal lung disease

...ngths of DNA at the ends of chromosomes, called telomeres. In normal cells, telomeres shorten each time the cell divides. When they reach a certain length, the cell stops dividing. In most cancerous cells, telomeres don't shorten during cell division, allowing the cells to remain effectivel...

Researchers use chemical from medicinal plants to fight HIV

...that contains repeated DNA sequences but no genes; telomeres act to protect the ends of the chromosomes and pre...ces from unraveling. Each time a cell divides, the telomeres get shorter, eventually causing the cell to reach ...elves that fight the invader. Generally, the telomeres in cells are sufficiently long that they can divid...

When cells go bad

... To protect an organism against cancer, most cells with broken or missing telomeres undergo "apoptosis," also known as cell suicide. But Golic and Simon Titen,...the skin, continue to divide over a lifetime. Each time a cell divides, the telomeres become shorter until, in rare cases, the rest of the chromosome is no longe...

Landmark study opens door to new cancer, aging treatments

...s of chromosomes, known as telomeres, thus preventing damage and the loss of genetic information during cell division. When telomerase is dormant, telomeres shorten each time a cell divides, leading eventually to genetic instability and cell death. By preserving chromosomes' integrity, telomerase allows ce...

UCLA study identifies mechanism behind mind-body connection

... BACKGROUND: Every cell contains a tiny clock called a telomere, which shortens each time the cell divides. Short telomeres are linked to a range of human diseases, including HIV, osteoporosis, heart disease and aging. Previous studies show that an enzyme within the cell, c...

UGA researchers discover mechanism that explains how cancer enzyme winds up on ends of chromosomes

... at UGA, "and the fact that telomerase keeps these telomeres growing when it should be inactive is crucial for ...ase reverse transcriptase. They are "recruited" to telomeres during what is called the "S phase" (for synthesis...localization of telomerase RNA to Cajal bodies and telomeres is specific to cancer cells where telomerase is ac...
telomeres in Biological Technology

Former Telomolecular CEO Clarifies SEC Settlement

...t observed when delivering inactive telomerase or linear strands of the same DNA. Studies performed by UCLA suggest that the elongation of chromosomal telomeres might prove to be effective and safe in the treatment of HIV in humans, while studies by other hospitals and universities suggest that certain disease...

Electroporation of Yeast Artificial Chromosomes

...g 16.1 kb plasmid, the DNA was isolated, purified over cesium chloride, and restriction digested with BamHI, thereby freeing the telomeres and resulting in a 14.4 kb linear DNA molecule. The restriction-digested DNA was microdialized (Millipore VS, 0.025 m) against T...
telomeres in Biological Definition

Cell division

...lts, and the cell is then referred to as senescent . Senescent cells deteriorate and die, causing the body to age. Cells stop dividing because the telomeres , protective bits of DNA on the end of a chromosome , become shorter with each division and eventually can no longer protect the chromosome. Cancer...

Cell nucleus

...ain genes which are not expressed by the cell (this type of heterochromatin is known as facultative heterochromatin) or are regions which make up the telomeres and centromeres of the chromosomes (this type of heterochromatin is known as constitutive heterochromatin). In multicellular organisms, cells are...

Chromosome

...the centromere. The ends of the chromosomes are special structures called telomeres . DNA replication begins at many different locations on the chromosome. ... called for determination of only the euchromatic portion of the genome. telomeres , centromeres , and other heterochromatic regions have been left undeter...

Cloning

... six. Aging of this type is thought to be due to telomeres , regions at the tips of chromosomes which preve...ads fraying every time a cell divides . Over time telomeres get worn down until cell-division is no longer pos...younger than they should be. Analysis of the cow's telomeres showed they had not only been 'reset' to birth-len...
telomeres in Biological Dictionary

Telomere

..."end" and mer╬┐s "part". So telomeres are not themselves genes, but neither are they .....e either (free) end of a eukaryotic chromosome; ' telomeres act as caps to keep the sticky ends of chrom...4 pages of encyclopedia entries, research ... Get telomeres (Monograph) (Cold Spring Harbor Monograph ... ...

Telomerase

...e found at the ends of eukaryotic chromosomes. The telomeres contain condensed DNA material, giving... telomerase ( ) n. An enzyme that is found in the telomeres of chromosomes in germ cells, stem cells, and ... of telomerase , the enzyme that helps maintain telomeres – small pieces of ... Telomerase da...

Semi-conservative

...hat " semi - conservative " means when we have got some ... " semi - conservative replication" ... Semi - conservative DNA replication through telomeres requires Taz1. Miller KM, Rog O, Cooper JP. ... cannot be sustained through semi - conservative replication. ... Semi conservative DNA Replic...

Heterochromatin

...c genomes is concentrated at and around ... Additional heterochromatin at telomeres protects the DNA at chromosome ends from ... Further studies revealed ... the highly repetitive, gene-poor DNA concentrated near the centromeres and telomeres of chromosomes. ... Online Shopping at DirectTextBook.com - Save up to 8...
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(Date:10/31/2014)... National Institutes of Health will facilitate communication among ... health research, from diagnosis to treatment. The Research ... the National Institute of Mental Health (NIMH), part ... institute,s RDoC initiative. , The aim of ... of research that translates basic science into clinical ...
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