BASF Podcast: The Chemical Reporter - Why Does Caffeine Have a Stimulating Effect?

... the hot brew that helps wake you up is well-known all over the world: caffeine. Caffeine doesn't only come from coffee beans. Most of the caffeine is synthetically manufactured by the chemical industry. In entertaining episodes our Chemical Reporter answers questions of our Podcast listeners on Chemistry in our e...

'Green chemistry' could ease manufacture, boost usefulness of cancer drug

...aclitaxel -- better known as the blockbuster drug Taxol. First isolated from the bark of the Pacific yew in 1967, paclitaxel has since been made by synthetically modifying an intermediate substance isolated from yew needles using toxic solvents or by fermenting cell cultures. Walker's method employs natural...

Frost & Sullivan Lauds Toscana Biomarkers' Outstanding Contributions to the R&D of Novel Biomarkers for the Diagnosis of Autoimmune Diseases

...lence in Research Award. The company demonstrated that the incorporation of synthetically modified peptides for the validation and discovery of biomarkers aids effec... response (autoimmune). "Researchers are in the process of introducing synthetically developed antigens subjected to chemical modifications," observes Suraj Ram...

Blood-clotting protein modified for people with hard-to-treat hemophilia

...tage of the blood-clotting protein Factor VIII (FVIII), people with Hemophilia A typically receive injections of FVIII derived from plasma or produced synthetically to control potentially life-threatening episodes of bleeding. Unfortunately as many as 1 in 3 people with Hemophilia A produce inhibitor antibodies, w...

Fallout From Failed AIDS Vaccine Could Dampen Research

...much promise in smaller, earlier studies. The vaccine used a harmless adenovirus -- a type of cold virus -- as a "vector" to deliver a set of three synthetically derived HIV genes. The hope was those genes would help prime the immune system against the virus that causes AIDS. The virus vector approach is a c...

UGA researchers 1 step closer to elusive cancer vaccine

...than the tumor-associated carbohydrate. Rather than using naturally derived and purified proteins and linkers, Boons and his team created a vaccine synthetically from scratch by stacking molecules together and arranging them in the appropriate configuration. In 2005, they created a fully synthetic vaccine that ...

Additives in Baby Products Raise Fresh Concerns in New Zealand

...s made such products "non-compliant under the joint Australia New Zealand Food Standards Code". Fos, which is refined from vegetable matter and can be synthetically produced, is permitted in Europe. The authority has asked the company to remove the products from the market. The company has refuted ...

Genetic Secrets Behind the Dragline Silk

...ser now that we have the full genetic recipe,' Hayashi said. With the ingredients and their genetic blueprint now known, it may be possible to synthetically produce the proteins by inserting the genetic sequences into host organisms such as bacteria, plants or animals, she said. Once the pure proteins are ...

Green Tea Compound may Be a Therapy for Rheumatoid Arthritis

... infusion to see that it worked by inhibiting these pathways. Ahmed says that these studies suggest that EGCG or molecules that could be derived synthetically from the EGCG found in green tea may be of therapeutic value by inhibiting the joint destruction in rheumatoid arthritis. Previously, Ahmed and...

Researchers Explore the Effect of Engineered Immune Cells on HIV

...virtually unnoticed by neutralizing antibodies that are roaming the body in search of disease. Faced with such a clever adversary, Wang wants to synthetically alter the HIV viral invaders and use their hollow shells as delivery vehicles to insert DNA that will counteract the infection. The "Cadillac" o...

synthetically in Medical Technology

Inovio Biomedical's Partners to Present New Data from Two Cancer Immunotherapy Clinical Trials

...esigned to express antigens that can induce an immune response specific to a cancer or infectious disease-causing organism. These plasmids are created synthetically and readily manufactured using well-established bacterial fermentation and purification technology. After a plasmid is delivered into muscle or tumor ...

Inovio: DNA delivery technology shows positive human results

...esigned to express antigens that can induce an immune response specific to a cancer or infectious disease-causing organism. These plasmids are created synthetically and readily manufactured using well-established bacterial fermentation and purification technology. After a plasmid is delivered into muscle or tumor ...

Inovio Biomedical's DNA Delivery Technology Shows Safety and Enhances Gene Expression & Tumor Responses in Interim Melanoma Clinical Study Results

...esigned to express antigens that can induce an immune response specific to a cancer or infectious disease-causing organism. These plasmids are created synthetically and readily manufactured using well-established bacterial fermentation and purification technology. After a plasmid is delivered into muscle or tumor ...

Inovio Biomedical Highlights Enhanced DNA Vaccine Potency with Electroporation DNA Delivery Technology and New Devices at Gene Therapy Meeting

...esigned to express antigens that can induce an immune response specific to a cancer or infectious disease-causing organism. These plasmids are created synthetically and readily manufactured using well-established bacterial fermentation and purification technology. After a plasmid is delivered into muscle or tumor ...

Vical Interim Clinical Results Demonstrate Safety and Tolerability of Inovio Biomedical's Electroporation DNA Delivery Technology

...esigned to express antigens that can induce an immune response specific to a cancer or infectious disease-causing organism. These plasmids are created synthetically and readily manufactured using well-established bacterial fermentation and purification technology. After a plasmid is delivered into muscle or tumor ...

synthetically in Medical Dictionary

Dextrose

...poglycemia. ... dextrose ( ) n. The dextrorotatory form of glucose, C 6 H 12 O 6 H 2 O, found naturally in animal and plant tissue and derived synthetically from glucose ( ) n. A monosaccharide sugar, C 6 H 12 O 6 , occurring widely in most plant and animal tissue ... Also known as dextrose , grape ...

synthetically in Biological News

Heparin prepared synthetically could replace animal-derived drug

Researchers at Rensselaer Polytechnic Institute and University of North Carolina at Chapel Hill have discovered an alternative way to produce heparin, a drug commonly used to stop or prevent blood from clotting. The findings could enable the current supply of the drug ?now extracted from animal tis...

Synthetic virus supports a bat origin for SARS

...ver a non-cultivatable virus. "The idea is, here's the virus, or the virus group, that we think became SARS-CoV," Denison said. "Let's see if we can synthetically recover the bat virus and test it in cultured cells and in animal models let the bat virus show us the pathways that it may have used to become a hum...

Researchers recreate SARS virus, open door for potential defenses against future strains

...Hill and Vanderbilt University Medical Center have synthetically reconstructed the bat variant of the SARS coronavi...nt. "Only three other teams of researchers have synthetically reconstructed a virus. In this case we reconstruct...and recover and characterize the viruses that were synthetically reconstructed and rescued in the laboratory. They ...

Can genetic information be controlled by light?

...t in the long term become possible to repair gene mutations using laser radiation. "In the field of nano-electronics it has already been shown that synthetically produced DNA can be used as 'nano-wires'. On the basis of the different reaction times of the molecules it might one day become possible to use laser ...

American Chemical Society's Weekly PressPac -- Sept. 24, 2008

...rocomputer tomography, and the implications for medicine, design of new materials, and other fields. "It is of interest in modern materials science to synthetically mimic these inorganic structures to create new coatings, materials or instruments for practical application," the article states. "We are convinced th...

ETH Zurich researchers develop antibody test

...or not someone has formed particular antibodies against various GPIs. To this end, the researchers use the purest possible GPIs. These can be produced synthetically and in large amounts in a laboratory, as the Seeberger team has demonstrated in earlier research. The new method involves affixing over 64 pad...

Nucleonics initiates hepatitis B clinical trial with expressed interfering RNA therapeutic

...ll produces thousands of copies of siRNA, and allows for a sustained therapeutic response versus the repeat administration expected to be required for synthetically created RNAi drugs. Moreover, one eiRNA drug molecule has the potential to encode four or more different siRNAs, enabling the attack of multiple targe...

Researchers create system to build transplant tissue

... One day soon, laboratories may grow synthetically engineered tissues such as muscle or cartilage needed for transplants. In a major step forward, Cornell engineers describe in the journal Nature Mate...

Small molecule dervived from Rb2/p130 could act as cancer therapeutic

...ed as a small molecule or peptide," Giordano said. They discovered a 39 amino-acid-long sequence, which they named Spa310. The molecule that was synthetically produced in the laboratory was introduced into mice that had been injected with tumor cells. "Tumor growth was inhibited and the tumors began to ...

Can engineered immune cells stop AIDS?

...y unnoticed by neutralizing antibodies that are roaming the body in search of foreign invaders. Faced with such a clever adversary, Wang wants to synthetically alter the HIV invaders and use their hollow shells as delivery vehicles to insert DNA that will counteract the infection. The "Cadillac" of ...

synthetically in Biological Technology

SAFC Biosciences(R) Defines Hydrolysate Components That Enhance Chinese Hamster Ovary (CHO) Cell Line Protein Production

...rocesses, is to fully characterize and define those components contained within them. As a result of these studies, EX-CELL CD Hydrolysate Fusion , a synthetically produced animal-component free, chemically defined alternative to undefined hydrolysates, has been created for use in CHO, NS0 and Sp2/0 biopharmaceut...

Medarex Announces Allowance of Investigational New Drug Application for Company's First Antibody-Drug Conjugate, MDX-1203

...expansion is the company's proprietary Antibody-Drug Conjugate platform. Medarex's proprietary ADC technology uses a cytotoxic agent that is a potent, synthetically manufactured prodrug (a DNA minor-groove binding alkylating agent) which is attached to an antibody using a stable peptide-based linker. Medarex belie...

J. Craig Venter Institute Researchers Publish Significant Advance in Genome Assembly Technology

...velopment of a synthetic genome by assembling the 5,386 base pair genome of bacteriophage phi X174 (phi X). They did so using short, single strands of synthetically produced, commercially available DNA (known as oligonucleotides) and using an adaptation of polymerase chain reaction (PCR), known as polymerase cycle...

New England Peptide Implements Quality Management System, Prepares for ISO 9001: 2008 Registration

... NEP will integrate the quality system with its PepTrend© knowledge base software. PepTrend facilitates the design, synthesis, and production of synthetically made peptides by incorporating data harnessed though each peptide production run with decades worth of proven peptide chemistry knowledge and trends. ...

Replikins Oral Vaccine Synthesized in 7 Days Protects 91% of Shrimp Against a Lethal Virus

...ine effectiveness reduced or lost because the target changed due to mutation. In contrast, the replikins vaccine found effective here was manufactured synthetically in 7 days. Viruses lethal to shrimp have been responsible for large losses to aquaculture worldwide. Replikins is forming a division to focus on the...

Venter Institute Scientists Create First Synthetic Bacterial Genome

...elopment of a synthetic genome by their work in assembling the 5,386 base pair bacteriophage FX174 (phi X). They did so using short, single strands of synthetically produced, commercially available DNA (known as oligonucleotides) and using an adaptation of polymerase chain reaction (PCR), known as polymerase cycle...

Quintessence Secures Financing

...ciences enable a more effective means of constructing proteins integral for drug research from their individual amino acids. They allow proteins to be synthetically built, eliminating the need for the more traditional and expensive method of formulating these proteins. Quintessence Biosciences will assist other re...

synthetically in Biological Definition

Peptide

...from proteins , which are also long chains of amino acids, by virtue of their size. Traditionally, those peptide chains that are short enough to make synthetically from the constituent amino acids are called peptides rather than proteins. The dividing line is at approximately 50 amino acids in length, since nat...

Peptide

...from proteins , which are also long chains of amino acids, by virtue of their size. Traditionally, those peptide chains that are short enough to make synthetically from the constituent amino acids are called peptides rather than proteins. The dividing line is at approximately 50 amino acids in length, since nat...