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syndromes in Medical News

Pharmion and MethylGene Present Favorable Clinical Data From Combination MGCD0103/Vidaza(R) Study in Myelodysplastic Syndromes and Acute Myelogenous Leukemia at The 49th American Society of Hematology (ASH) Meeting

* Recommended Phase II Dose of MGCD0103 Determined as 90 mg * 53% of Patients Treated with 90 mg Dose Achieved a Clinical Response * Patients with Responses Experienced a 66% Reduction in the Risk of Death Compared to Non-responders ATLANTA, Dec. 10 /PRNewswire-...

Eisai Will Initiate First Head-to-Head Study Comparing Dacogen(R) (decitabine for injection) and Vidaza(R) (azacitidine) in Patients with Myelodysplastic Syndromes

Randomized Comparator Study to Evaluate Efficacy of Commercially Available Hypomethylating Agents WOODCLIFF LAKE, N.J., Dec. 2 /PRNewswire/ -- Eisai Corporation of North America today announced that it plans to initiate the first clinical trial evaluating the activity of Dacogen(R) (deci...

Clopidogrel reloading worthwhile in acute coronary syndromes

CHICAGO, Ill. (April 1, 2008) Many patients who come to the cardiac catheterization laboratory for percutaneous coronary intervention (PCI) are already taking 75mg of clopidogrel daily to prevent unwanted blood clotting. Even so, an additional 600-mg reloading dose of clopidogrel significantly im...

Treating depression may improve recovery of heart rate variability following coronary syndromes

Patients with depression appear to have an impaired ability to recover their heart rate variability following acute coronary syndromes such as heart attack, a factor that could increase their risk of coronary death, according to a report in the September issue of Archives of General Psychiatry, on...

Diabetes appears to increase risk of death for patients with acute coronary syndromes

Individuals with diabetes and acute coronary syndromes (ACS) such as a heart attack or unstable angina have an increased risk of death at 30 days and one year after ACS, compared with ACS patients without diabetes, according to a study in the August 15 issue of JAMA. The presence of elevated bl...

Carnegie Mellon develops innovative method to detect genetic causes of complex diseases

...ists at Carnegie Mellon University have developed an analytical technique to detect the multiple genetic variations that contribute to complex disease syndromes such as diabetes, asthma and cancer, which are characterized by multiple clinical and molecular traits. Rather than searching one at a time for gene...
syndromes in Medical Technology

FDA Accepts sNDA for Alternative Dosing Regimen for Dacogen(R) (decitabine for injection) to Treat Patients with Myelodysplastic Syndromes (MDS)

WOODCLIFF LAKE, N.J., July 8 /PRNewswire/ -- Eisai Corporation of North America today announced that the U.S. Food and Drug Administration (FDA) has accepted for review the company's supplemental new drug application (sNDA) for an alternative five-day dosing regimen for Dacogen(R) (decitabine for ...

Vion Pharmaceuticals Announces Presentation of Data of Cloretazine(R) (VNP40101M) in Elderly Patients with High-Risk Myelodysplastic Syndromes at the EHA Annual Meeting

NEW HAVEN, Conn., June 13 /PRNewswire-FirstCall/ -- VION PHARMACEUTICALS, INC. (Nasdaq: VION ) today announced that data from a previously conducted Phase II trial of its lead anticancer agent Cloretazine(R) (VNP40101M) in elderly patients with acute myelogenous leukemia (AML) and high-risk m...

Pharmion Submits European Marketing Authorization Application (MAA) for Vidaza(R) in Patients with Higher-Risk Myelodysplastic Syndromes (MDS)

- MAA submission based on data from largest Phase 3 study conducted in MDS - Vidaza therapy confers highly significant 9.4 month median overall survival advantage compared to conventional care regimens - Two year overall survival rate of 50.8% for Vidaza compared to 26.2% for ...

Vidaza Significantly Extends Overall Survival by 74% in Phase 3 Trial in Myelodysplastic Syndromes (MDS)

Two year survival rate of 50.8 percent for Vidaza versus 26.2 for conventional care regimens 9.4 months median survival benefit for patients on Vidaza compared to conventional care regimens Only agent to demonstrate survival benefit in MDS compa...

Eisai Provides Preliminary Efficacy Update On EORTC Phase III Trial of Dacogen(R) Versus Supportive Care in Patients With Myelodysplastic Syndromes

Submission of Five-Day Dosing Regimen sNDA Targeted for Fiscal Year-end 2008 WOODCLIFF LAKE, N.J., July 1, 2008 /PRNewswire/ -- Eisai Corporation of North America today announced the preliminary efficacy data from a trial initiated in 2002 comparing Dacogen(R) ...

SuperGen Comments on Preliminary Efficacy Update on EORTC Phase 3 Trial of Dacogen(R) Versus Supportive Care in Patients With Myelodysplastic Syndromes

Reiterates 2008 Annual Financial Guidance DUBLIN, Calif., July 1 /PRNewswire-FirstCall/ -- SuperGen Inc. (Nasdaq: SUPG), a pharmaceutical company dedicated to the discovery, rapid development and commercialization of therapies for solid tumors and hematological malignancies, tod...
syndromes in Medical Products

Total PSA IRMA Test

Description:...urethral glands, breast cancer tissues, breast fluids, amniotic fluid and other [7]. Urinary PSA has also been measured in women with hyperandrogenic syndromes such as polycystic ovarian syndrome [8]. Vessella RL. Clin Chem 39:2035, 1993. Papsidero LD, et al. Cancer Res 40:2428, 1980. Kuriyama...
Company:Diagnostic Systems Laboratories, Inc.

Total PSA ELISA Test

Description:...urethral glands, breast cancer tissues, breast fluids, amniotic fluid and other [7]. Urinary PSA has also been measured in women with hyperandrogenic syndromes such as polycystic ovarian syndrome [8]. Vessella RL. Clin Chem 39:2035, 1993. Papsidero LD, et al. Cancer Res 40:2428, 1980. Kuriyama...
Company:Diagnostic Systems Laboratories, Inc.

Surgical Recall, 4th Ed.

Features:...iographs More useful mnemonics and other memory aids than ever before New chapters on Ward and Clinical Procedures, Respiratory Care, and Surgical syndromes All Chapters revised with the most up-to-date surgical information With Skyscape's patented smARTlink™ technology, SurgRecall4™ can easi...
Company:Skyscape, Inc.

Pediatric ThermoWrap™

Features:...nables true normothermia (36.5° - 37.5°) Controls induced hypothermia and precise rewarming Eliminates temperature-related perioperative syndromes One-piece garment that facilitates wrapping of individual parts of the body Biocompatible Latex-free Anti-static Secured through preattached...
Company:MTRE Advanced Technologies Ltd.

ELPHA 4 Conti

Features:...to enhance in treatment for individual requirements. As something unique ELPHA 4 Conti offers symptomatic management of acute, chronic and cyclic pain syndromes with a dedicated pain relief programme of the pelvic floor and other muscle related pain with the use of surface electrodes. ...
Company:Danmeter
syndromes in Medical Definition

Cachexia

...n-, Interferon gamma (IFNɣ), and Interleukin 6 (IL-6), as well as the tumor secreted proteolysis inducing factor (PIF). Related malnutrition syndromes are kwashiorkor and marasmus , although these do not always have an underlying causative illness; they are most often symptomatic of severe malnut...

Central tolerance

... of the autoreactive cell) [4] Division to a regulatory lineage Genetic defects in these processes lead to autoimmunity, such as in the human syndromes APS-1 and IPEX . References ^ http://www-immuno.path.cam.ac.uk/~immuno/part1/lec11/lec11_97.html ^ Sprent J, Kishimoto...

Hematopathology

... Cells The major disease of hematopoietic cells fall into several categories, which include chronic myeloproliferative disease , myelodysplastic syndromes , leukemias , lymphomas , plasma cell neoplasms , and histiocytic and mast cell neoplasms. Hematopathologists from all over the world have agreed...

Muscle atrophy

... syndrome that is a co-morbidity of cancer and Congestive Heart Failure ; Chronic Obstructive Pulmonary Disease ; burns, liver failure, etc. Other syndromes or conditions which can induce skeletal muscle atrophy are congestive heart disease and liver disease. Other muscles diseases, distinct from ...

Ramón Carrillo

... same period, Carrillo attained valuable results investigating the brain herniations protruding into blood cysterns (cysternal herniations) and the syndromes occurring after a closed brain traumatism or contussion (postcommotional syndromes); he discovered the " Carrillo's disease " or epidemic acute papil...
syndromes in Medical Dictionary

Colorectal polyps

...or rectum. ... single or many polyps , and they become ... 1 Colorectal polyp . 1.1 Inherited polyposis syndromes. 1.2 Non-inherited polyposis syndromes ... Main article: Colorectal polyp . Colon polyps are uncommonly ... ...

Vulvodynia

...aign Brochure ... Vulvodynia ... Vulvodynia : towards understanding a pain syndrome. Proceedings ... Vulvodynia refers to a group of pain syndromes affecting the vulva — the outer ... Vulvodynia , as with most chronic pain conditions, can have a profound impact on ... Up-to-the-minute n...

Vitamin B

...ay. Thiamin (thiamine), vitamin B1 ... Vitamin B supplements have been used to treat leg ... B Vitamin deficiency and neuropsychiatric syndromes in alcohol misuse. ... Vitamin Express offers high-quality health supplements at discounted prices, along with ... Vitamin A. Vitamin B . ...

Viral arthritis

... arthritis . Ytterberg SR. Division of Rheumatology, Mayo Clinic, Rochester, MN 55905, USA. ... Identifying viral infections related to rheumatic syndromes ... Viral arthritis . Calabrese LH, Naides SJ. ... and other common forms of viral arthritis , such as that caused by parvovirus B19. ... ...

Venous insufficiency

... in your leg veins are ... Families > Vascular Conditions, Tests, Treatments > Chronic Venous Insufficiency ... Venous insufficiency syndromes are caused by valvular incompetence in the ... Deep venous insufficiency occurs when the valves of the deep veins are damaged ... Venous in...

Tics

...king, eye ... In this section, several complex motor phenomena are defined, including tics , compulsions, stereotypies, mannerisms, and habits. syndromes that have a sense of ... A description of the tics of Tourette's Syndrome. ... Click here to skip more descriptions, and go straight to a list o...
syndromes in Biological News

Gene for immune deficiency syndromes found

A newly discovered gene mutation may account for many cases of immune deficiency, in particular two syndromes known as immunoglobulin A (IgA) deficiency and Common Variable Immunodeficiency (CVID), report researchers in the July issue of Nature Genetics. The discovery may lead to a new diagnostic t...

Scientists track impact of DNA damage in the developing brain

...ins of neurological disease. The research also reflects growing scientific interest in damage to single strands of DNA. "A variety of human disease syndromes result from problems in the DNA-repair system," explained McKinnon, the paper's senior author. DNA is the double-stranded molecule found in nearly ...

Further gene mutations linked to autism risk

...rols. The findings are published June 26 in the open-access journal PLoS Genetics . Autism spectrum disorders (ASDs) are common neurodevelopmental syndromes with a strong genetic component. ASDs are characterized by disturbances in social behavior, impaired verbal and nonverbal communication, repetitive be...

'Coral Disease Handbook: Guidelines for Assessment, Monitoring and Management'

...tudying the ecology, and mitigating the damage, of coral diseases. Accompanying the book is a set of identification cards for identifying diseases and syndromes known globally. Designed for reef managers by international experts in coral disease, the Handbook outlines procedures for describing indicators, ...

Peter Baumann named Howard Hughes Medical Institute Early Career Scientist

... from becoming too short, Dr. Baumann's research team hopes to lay the foundation for the development of treatments for cancer as well as degenerative syndromes such as dyskeratosis congenita and aplastic anemia. Dr. Baumann leads an eight-person team at the Stowers Institute composed of postdoctoral resea...

New edition available for essential virology reference

...ck Hayden of the University of Virginia Health System. Clinical Virology is divided into two major sections. The first addresses infections and syndromes related to particular organ systems, as well as the fundamentals of modern medical virology, including immune responses and vaccinology, diagnostics, ...
syndromes in Biological Technology

EMEA Accepts for Review Vidaza(R) Marketing Authorization Application for Higher-Risk Myelodysplastic Syndromes

Application to be reviewed under European Accelerated Assessment Procedure BOULDER, Colo., Feb. 7 /PRNewswire-FirstCall/ -- Pharmion Corporation (Nasdaq: PHRM ) today announced that the European Medicines Agency (EMEA) has accepted for review the Company's Marketing Authorization Application (...

Pharmion's Oral Azacitidine Granted Fast Track Status for Myelodysplastic Syndromes

BOULDER, Colo., Aug. 29 /PRNewswire-FirstCall/ -- Pharmion Corporation (Nasdaq: PHRM ) today announced that the U.S. Food and Drug Administration (FDA) has granted Fast Track designation for oral Azacitidine in the treatment of Myelodysplastic Syndromes (MDS). Fast Track programs are designe...

Multiple Types of Heart Attacks Reduced by Prasugrel in TRITON-TIMI 38 Trial

...study and showed that patients with acute coronary syndromes (ACS) undergoing percutaneous coronary interventio... and fatal bleeding.(5) About Acute Coronary syndromes Acute coronary syndromes (ACS), which includes heart attack and unstable an...

NeurogesX Receives European Commission Approval for Qutenza(TM)

...ation, diabetes, life expectancy for HIV-positive individuals, and heightened awareness among the medical community. Peripheral neuropathic pain syndromes can be difficult to treat and current treatment options may be limited by the need for frequent dosing and undesirable systemic side effects. Ab...

Ambry Genetics Announces the Addition of Array CGH Services Through Partnership With Baylor College of Medicine

...gonucleotide arrays through a partnership with Baylor College of Medicine . Large chromosomal abnormalities that are associated with over 270 genetic syndromes can be easily identified via analysis of each 105K whole genome and mitochondrial array. The partnership with Baylor College of Medicine equips Ambr...

NeurogesX Presents Two Posters at 61st Annual American Academy of Neurology Annual Meeting

... population, diabetes, life expectancy for HIV-positive individuals, and heightened awareness among the medical community. Peripheral neuropathic pain syndromes can be difficult to treat and current treatment options are often limited by poor tolerability, the need for titration, and administration of multiple...
syndromes in Biological Definition

Cancer

...rgically, if possible. Heredity Most forms of cancer are "sporadic", and have no basis in heredity. There are, however, a number of recognised syndromes of cancer with a hereditary component. Examples are: breast cancer and ovarian cancer in female carriers of BRCA1 tumors of various end...

Insulin

...5 Signal transduction 6 The brain and hypoglycemia 7 Diseases and syndromes caused by an insulin disturbance 8 Insulin as a medication 8.1 ...) external insulin (usually injected subcutaneously) Diseases and syndromes caused by an insulin disturbance There are several conditions in which in...
syndromes in Biological Dictionary

Motor neuron

...s ( flexor muscles) neurons ( flexor muscles) ... UPPER MOTOR NEURON SYNDROME DAMAGE TO ... Historical Aspects of Lower Motor Neuron syndromes ... Benign, focal motor neuron disorders, such as monomelic amyotrophy, were subsequently reported. ... Sporadic motor neuron disorders wit...
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(Date:4/18/2014)... University psychologists have made a brain-related discovery that ... disorders. , This discovery opens up the possibility ... suppress a specific brain activity that the researchers ... The Journal of Neuroscience has just ... McDonald, an associate professor of psychology and his ...
(Date:4/17/2014)... non-cancerous prostate tissue may have nearly twice the risk ... inflammation, according to results of a new study led ... , The link between persistent inflammation and cancer was ... those with a Gleason score between 7 and ... and rapidly growing prostate cancers. , "What we,ve shown ...
(Date:4/17/2014)... April issue of Experimental Biology and Medicine ... Rex Gaskins and Paul Kenis in the Institute ... the University of Illinois Urbana-Champaign describe their recent ... underlie a variety of cell functions including energy ... crucial roles in regulating normal cellular behavior, redox ...
(Date:4/17/2014)... A Northwestern University synthetic biology team has created ... create programmable therapeutics that could travel the body ... disease. , Engineering cell-based, biological devices that monitor ... in clinical synthetic biology. However, no existing technology ... a patient,s physiological state and respond in a ...
(Date:4/17/2014)... IL, April 17, 2014-- Colic affects about one in ... for numerous pediatric visits during the first several months ... colic symptoms was showing promise; however, the April 1, ... (BMJ2014;348:g2107; Sung, Valerie) reported on a study, "Probiotics and ... L reuteri for infant colic did ...
Breaking Medicine News(10 mins):Health News:Scientists discover brain's anti-distraction system 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 2Health News:Chronic inflammation linked to 'high-grade' prostate cancer 3Health News:Live cell imaging reveals distinct alterations of subcellular glutathione potentials 2Health News:Building 'smart' cell-based therapies 2Health News:New study says probiotic use for infant colic is not effective in reducing symptoms 2
(Date:4/18/2014)... Seeds that sprout as soon as they,re planted may ... to be more careful. In the wild, a plant whose ... would risk disaster. More than just an insurance policy against ... seed dormancy has long-term advantages too: Plants whose seeds ... to more species, finds in a team of researchers working ...
(Date:4/17/2014)... densely forested and most densely populated quadrant of the ... values and practices. Disturbances associated with those needs, such ... have set the stage for management issues of considerable ... The report Five anthropogenic factors that will radically ... United States was published recently by the ...
(Date:4/17/2014)... Suddenly there was a word for chili peppers. Information ... along with a study of the appearance of words ... understand where jalapeos were domesticated and highlight the value ... (Kraig Kraft et al.) of nine papers presented in ... the National Academy of Sciences on plant and ...
Breaking Biology News(10 mins):Plants with dormant seeds give rise to more species 2Five anthropogenic factors that will radically alter northern forests in 50 years 2Five anthropogenic factors that will radically alter northern forests in 50 years 3Chickens to chili peppers 2Chickens to chili peppers 3
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