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'Exercise pill' switches on gene that tells cells to burn fat

By giving ordinary adult mice a drug - a synthetic designed to mimic fat - Salk Institute scientist Dr. Ronald M. Evans is now able to chemically switch on PPAR-d, the master regulator that controls the ability of cells to burn fat. Even when the mice are not active, turning on the chemical switch activates the same fat-burning process that occurs during exercise. The resulting shift in energy b...

Switching to new anti-bacterial targets: Riboswitches

The recently emerged field of bacterial riboswitches may be a good hunting ground for effective targets against bacterial infection, according to a report by Yale researchers in the journal Chemistry and Biology. Rona...

Nano machine switches between biological and silicon worlds

"Frankly, some researchers didn't think what we were attempting was possible," says Dr Keith Firman, at Portsmouth University and Mol-Switch project coordinator, funded under the European Commission's Future and Emerging Technologies initiative. "However, we got our molecular switch to work." The upshot is that the Mol-Switch project was far more successful than expected. The team's switch...

Flick of a protein switches immune response

A single protein can turn on and off a key component of the immune system by changing partners in an elegant genomic dance, said researchers at the University of Southern California and Harvard Medical School. Because autoimmune diseases ?such as arthritis, allergies and dozens of other illnesses ?begin when the body's defenses respond at the wrong time or place, the on-off mechanism for...

Light-sensitive photoswitches could restore sight to those with macular degeneration

A research center newly created by the University of California, Berkeley, and Lawrence Berkeley National Laboratory (LBNL) aims to put light-sensitive switches in the body's cells that can be flipped on and off as easily as a remote control operates a TV. Optical switches like these could trigger a chemical reaction, initiate a muscle contraction, activate a drug or stimulate a nerve cell...

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Unusual Tumor-Suppressor Gene Switches Off in Lung Cancer

Researchers at Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, have found a tumor suppressor gene that could be of vital significance in the development of head and neck cancers as well as lung cancer. //Their study shows that activating this particular gene could slow up the development of the aforementioned ca...

Nanotechnology at its best: Nanomotors And Mechanical Nanoswitches

Physics has been coupled and nanotechnology is spreading its wings to medicine and pharmaceuticals.// Julius Springer Prize for Applied Physics for 2006 will be awarded to Dr. Viola Vogel for her creative and pioneering work on bionanotechnology exploring single molecule mechanics and nanomotors for technical applications. Engineering principles of biological nanosystems f...

Breast Cancer Treatment Switches to more Modern Therapy

Post Menopausal women with early breast cancer who have been receiving the 30-year-old tamoxifen treatment can now change to a more modern therapy with the drug, Arimidex// under a new European licence granted to drug firm AstraZeneca. The company AstraZeneca has stated that Arimidex, an aromatase inhibitor, will be made available to women who have already received a partial course of t...

Master Switches Found for Adult Blood Stem Cells

Johns Hopkins Kimmel Cancer Center scientists have found a set of "master switches" that keep adult blood-forming stem cells in their primitive state//. Unlocking the switches' code may one day enable scientists to grow new blood cells for transplant into patients with cancer and other bone marrow disorders. The scientists located the control switches not at the gene level, but farther...

Research Studies on Molecular Switches of Gene

A single molecular on switch triggers gene activity that cause effects ranging from learning and memory capabilities to glucose production in the liver was discovered by scientists of St.Jude Childrens Research hospital . The on switch, a protein called CREB, is a transcription factora molecule that binds to a section of DNA near a gene and triggers that gene to make the specific p...
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(Date:8/20/2008)... NEWTON, Mass., Aug. 20 /PRNewswire/ -- Questex M...o-business media company and owner of,American Spa... and the,International Beauty Shows, the Internati...) and the SPATEC appointment events today announce...stry portals SpaTrade (, http://www.SpaTrade.com ...
(Date:8/20/2008)... Survey Report Is Available at http://ww...Newswire/ -- A new survey released today,documents...re leveraging,health information technology (HIT) ...The survey results highlight the need for many HIT...dization and,interoperability to optimize clinical...
(Date:8/20/2008)...use postponed reproductive onset in teen, adult fe...EDNESDAY, Aug. 20 (HealthDay News) -- Alcoholism i...ccording to a study that compared women,s and men,... age when they had their first child. , The re...ian twins born between 1893-1964 (3,634 female and...
Breaking Medicine News(10 mins):Health News:Cytiva's one45 Software Rebrands Healthcare Education Administration Products 2Health News:Cytiva's one45 Software Rebrands Healthcare Education Administration Products 3Health News:Cytiva's one45 Software Rebrands Healthcare Education Administration Products 4Health News:Questex Acquires Leading Spa Industry Portal and Spa Executive Business Networking Site and Events 2Health News:Questex Acquires Leading Spa Industry Portal and Spa Executive Business Networking Site and Events 3Health News:New Health IT Survey for Care Management Services Shows Opportunities for Integration, Standardization and Innovation 2Health News:New Health IT Survey for Care Management Services Shows Opportunities for Integration, Standardization and Innovation 3Health News:Women's Alcohol Use Tied to Delayed Childbearing 2
(Date:8/20/2008)...g (MRI) isn,t just for capturing detailed images o...ents and technology developed by Carnegie Mellon U...o visualize with "exquisite" specificity cell po...ity to non-invasively locate and track cells, such...reatment of cancer, inflammation, and autoimmune d...
(Date:8/20/2008)...d with Additional Funding by Syncom Venture Partn...uding Lockheed Martin, GE Security, Baker Capit...swire/ -- Clear(R), the fast pass for airport,secu.... Led by new investor,Spark Capital, this round al...ers, and existing investors Lockheed Martin, GE Se...
(Date:8/20/2008)...odeine may be risky for some,breastfeeding mother...estern Ontario, and the Hospital for Sick Children...ren published research in the journal, Clinical P...e codeine used in some pain relief drugs can actua...s when ingested by some breastfeeding mothers. , ...
(Date:8/20/2008)...t an interdisciplinary and coordinated research ag...ce and influencing policy, a group of experts has ...g of how mercury moves through the marine ecosyste...th,s Toxic Metals Research Program convened the gr...tors, and public health experts in November 2006 t...
Breaking Biology News(10 mins):Carnegie Mellon MRI technology that non-invasively locates, quantifies specific cells in the body 2Carnegie Mellon MRI technology that non-invasively locates, quantifies specific cells in the body 3Clear(R) Secures $44.4 Million in Venture Funding 2Clear(R) Secures $44.4 Million in Venture Funding 3Codeine not safe for all breastfeeding moms and their babies 2Dartmouth workshop sets research agenda for environmental mercury 2Perot Systems and ChinaSoft to Pursue Chinese Healthcare Opportunities 14594 1Perot Systems and ChinaSoft to Pursue Chinese Healthcare Opportunities 14594 2Springer to publish new journal focusing on ethical issues in neuroscience 14592 1Springer to publish new journal focusing on ethical issues in neuroscience 14592 2Uric acid may provide early clues to diabetic kidney disease 14589 1Uric acid may provide early clues to diabetic kidney disease 14589 2Cystic Fibrosis Foundation announces 245 million initiative to enhance care for adults with CF 14586 1Cystic Fibrosis Foundation announces 245 million initiative to enhance care for adults with CF 14586 2
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