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subgroups in Medical News

Living in U.S. May Raise Hispanics' Cancer Risk

...t. Living the American lifestyle is probably to blame, say researchers from the University of Miami Miller School of Medicine. Of three Hispanic subgroups they studied -- Puerto Ricans, Mexicans and Cubans -- Puerto Ricans had the highest cancer rates and Mexicans the lowest. The risk of cancer among Cub...

Advanced targeted therapies effective as first-line treatment for lung cancer

...egative subgroup was shorter than that of the mutation-positive group (with a median of 2.1 vs. 8.4 months). There was no difference between these two subgroups in the chemotherapy group. "Gefitinib did not improve overall survival over the standard chemotherapy," said Jin S. Lee, M.D. of the National Cance...

MULTAQ(R) (dronedarone) for Atrial Fibrillation or Atrial Flutter Now Available in the United States

...om any cause by 24% (p<0.001) when compared to placebo, meeting the study's primary endpoint. This reduction was generally consistent across study subgroups based on baseline characteristics or medications. Patients taking MULTAQ had higher rates of diarrhea, nausea, bradycardia, QT-interval prolongation a...

Sunitinib Benefit Explored in Poor-Prognosis Kidney Cancer

...itute and Harvard Medical School in Boston, and Dr. Toni K. Choueiri of Dana-Farber and Harvard. "Thus, claiming sunitinib as a 'standard' in these subgroups remains controversial. An oncologist might not have access to such trials in practice, however, and based on available information the use of sunitini...

Brain Imaging (MRI/PET) and Measurements of Proteins in Spinal Fluid May Improve Alzheimer's Prediction and Diagnosis

... healthy, 111 MCI, 60 Alzheimer's). Using the automated approach, rCMglc was measured by PET in 32 brain regions. Participants were divided into seven subgroups across normal, MCI, and AD categories, based upon their initial diagnosis and results of subsequent memory and thinking tests up to 3 years after the ...

New lung cancer staging system revealed

...ith NSCLC through the addition of many new patient subgroups and reclassification of some previous subgroups. ... The extensive data resulted in the addition of subgroups and the reclassification of select patient subgroups based on patient prognosis or overall survival rat...

FDA Approves Multaq(R) for Patients with Atrial Fibrillation or Atrial Flutter

...om any cause by 24% (p<0.001) when compared to placebo, meeting the study's primary endpoint. This reduction was generally consistent across study subgroups based on baseline characteristics or medications. Patients taking Multaq(R) had higher rates of diarrhea, nausea, bradycardia, QT-interval prolongatio...

Metabolic factors may play a role in risk for breast cancer

...bolism is tied to features of the metabolic syndrome. "Though estrogens are produced in adipose tissues, just how these are metabolized in various subgroups of women needs better study," he said. "In addition, the hyper-inflammatory state of obesity and the metabolic syndrome need to be better described re...

MDOUTLOOK(R) Quick Polls Report on Clinical Integration of Key Oncology Developments Following ASCO 2009

... meeting of the American Society of Clinical Oncology (ASCO) in Orlando, Florida. Based on patient volume, clinical focus and other criteria, specific subgroups of MDOUTLOOK's global database of 43,000 cancer treaters were selected for participation in one of the following Quick Polls: integration of hot topic...

Aerobically unfit young adults on road to diabetes in middle age

...omen and young African Americans are less aerobically fit than men and white adults in the same age group, placing a larger number of these population subgroups at risk for diabetes. "These young adults are setting the stage for chronic disease in middle age by not being physically active and fit," said Me...
subgroups in Medical Technology

Responses After Completion of Therapy Increase Pixantrone Complete Remission (CR)/Unconfirmed Complete Remission (CRu) Rate to 24% and Overall Response Rate (ORR) to 40% Compared to 7% and 14% for Comparator Agents in Phase III EXTEND Trial in 3rd Line Th

...XTEND (PIX 301) clinical trial data enhances previously reported superior response rates for pixantrone over comparator including in high risk patient subgroups Additional Clinical Studies Also Highlighted at Pan Pacific Conference Randomized phase III; PIX 302-Pixantrone plus ritux...

Micromet's Blinatumomab Achieves Primary Endpoint in Phase 2 Study with Acute Lymphoblastic Leukemia Patients

... patients have shown an MRD response, thus qualifying the trial as having met its primary endpoint before the completion of the study. Patients in all subgroups responded to treatment with blinatumomab, including bcr-abl positive patients after failure of treatment with bcr-abl inhibitors, and patients with t(...

Optimer Pharmaceuticals Presents Results From Fidaxomicin Phase 3 Study for the Treatment of Clostridium difficile Infection

...atient status (in-patient/out-patient), age (under/over 65) and strain type (BI/NAP1/027). Most notably, fidaxomicin showed a reduction across several subgroups in recurrence rates compared to Vancocin in both out-patient and in-patient settings, as well as in patients both over and under the age of 65. The r...

Autism Studies Presented at Mid-Atlantic Research Consortium Meeting

...ssociate director of the IDDRC at Children's Hospital. "Researchers ultimately must subclassify patients based on genetics and behavior, then focus on subgroups of ASDs in animal models. Scientists will then translate those findings into therapies personalized to a child's specific subtype of autistic disorder...

InspireMD Announces the Enrollment of the 1st Patient in the MGuard iMOS Registry, the Registry Will Enroll 1000 Patients

...d: "The iMOS registry is very important for us in order to understand the clinical performance of MGuard(TM) and to be able to analyze special patient subgroups and modes of use of the MGuard(TM). Currently the MGuard(TM) is mostly used in AMI, SVG, and thrombus containing lesions. We hope that the iMOS regist...

Clinical Data Reinforce Safety and Efficacy of Boston Scientific's Two Drug- Eluting Stent Platforms

... included 892 patients randomized to the PROMUS (XIENCE V) Stent and 410 patients treated with the TAXUS Stent. While overall pooled results and some subgroups at two years favored the PROMUS (XIENCE V) Stent for rates of Major Adverse Cardiac Events (MACE), the MACE results in patients with diabetes favored ...

DaVita Abstracts Accepted Into National Kidney Foundation's 2009 Spring Symposium

...: Mark A. Livingston DaVita Inc., Warren, MI -- Title: Mortality of 5-Year Time-Averaged Low Serum Calcium <8.5 mg/dL in subgroups of Hemodialysis (HD) Patients Authors: Jessica E Miller(1), Elani Streja(1), Csaba P Kovesdy(2), David Van Wyck(3), Allen R. Nissen...

FDA Submission of B-R-A-H-M-S MR-proANP Kryptor

... highly useful marker for diagnosing congestive heart failure. Furthermore it provides additional information especially in diagnostically challenging subgroups such as obesity, higher age or renal dysfunction compared to routinely used markers. First presented at the 2008 ESC Congress and subsequently ...

New PRO2000 HIV-Prevention Findings Important Milestone on Path Toward Development of Effective Vaginal Microbicide

...is not statistically significant, the data is highly supportive. Additionally, the protective effect of PRO2000 is corroborated by analysis of various subgroups of women within the study. To bolster these results additional trials must be run to generate confirming data. Fortunately, another study of PR...

Dacogen(R) (decitabine for injection) Data Presented on a Phase II Clinical Trial in Elderly Patients with Acute Myeloid Leukemia (AML)

... patients and CR with incomplete blood count recovery (CRi) in 2 percent. The median time to response was three months, and responses were seen in all subgroups of patients, including patients with the poorest prognoses. Additionally, 44 percent of patients maintained stable disease during a median five cycle...
subgroups in Biological News

New HIV study identifies high-risk subgroups of adolescents

A new study from the Bradley Hasbro Children’s Research Center and Brown Medical School unveils profiles of adolescents at the greatest risk for HIV. Amongst a group of high-risk teens, researchers found that those at highest risk for the disease (those who engaged in the most unprotected sex acts)...

Race/ethnicity, family income and education associated with sugar consumption

...eening, genetic testing and family history of cancer. A limited number of questions about diet were included to allow characterization of the diets of subgroups of the population in terms of cup equivalents of fruits and vegetables, teaspoons of added sugar, grams of fiber, dairy servings, and calcium intake. ...

Gene expression findings a step toward better classification and treatment of juvenile arthritis

...t form was more complicated, or if there were more subgroups than originally thought. They included children wi...s of gene expression that indicated at least three subgroups of polyarthritis. There was an older subgroup (ave... frequently have a positive ANA, than to the other subgroups of polyarticular JIA. Dr. Colbert says the new ...

Publication sets guidelines across cancer therapies: Ensuring the best in patient management

...o critical imaging procedures to ensure that patients get the right treatment early on in their cancer." Most anticancer drugs are effective only in subgroups of patients, and many of the various techniques developed to monitor tumor response to these drugs have proven to be inadequate. "FDG PET imaging, on ...

USC researchers identify gene variant associated with both autism and gastrointestinal dysfunction

...s are likely to result in different types of autism features, Levitt says. "We believe that there are other genes that will help identify different subgroups of individuals who have autism spectrum disorder," he says. "We also believe that there needs to be research looking at whether the children with co-o...

Snails and humans use same genes to tell right from left

...ch is evidence of a conserved pathway," Patel said. Genes similar to nodal have been found throughout the so-called deuterostomes, one of the three subgroups of bilateral animals that includes not only vertebrates, but also sea urchins and sea squirts. But the most common lab animals, fruit flies and nem...

Blood 'fingerprints' for cancer

... surgery, and the ability to forecast disease recurrence. The new technique will also be useful to pharmacological companies in identifying population subgroups who are responsive to drugs that have failed in phase III clinical trials. ...

Researchers study facial structures, brain abnormalities to reveal formula for detection of autism

...ures of autistic children to those of non-autistic children; no one has ever done that." Duan's facial and brain imaging work will focus on two ASD subgroups hypothetically identified by Judith Miles, the William and Nancy Thompson Endowed Chair in Child Health at the Thompson Center. She has observed and d...

Study identifies trends of vitamin B6 status in US population sample

...tion Research Center on Aging at Tufts University. "We also identified four subgroups where this trend seemed most prominent: women of reproductive age, especial...dy raises is whether, due to aging, genetics, or exposures, some population subgroups need supplements to achieve the current biochemical definition of adequate ...

New insights into the diversity of Creutzfeldt-Jakob disease agents

...d France have identified four separate biochemical subgroups in a selection of cases of Creutzfeldt-Jakob disea...access journal PLoS Pathogens, suggests that these subgroups could represent distinct prion strains in what is ...authors identified four distinct biochemical PrPSc subgroups in 41 sCJD cases. These...
subgroups in Biological Technology

Large-scale genetic study sheds new light on lung cancer

...in the disease, and described patterns of genetic mutations among different subgroups of lung cancer patients, including smokers and never-smokers. More than ...earchers also analyzed the patterns of genetic changes seen among different subgroups of lung adenocarcinoma patients, including smokers. About 90 percent of ...

ProMetic announces Octapharma publication of PRDT'S prion removal resin in Octaplas(R) manufacturing process at 30th International Congress of the International Society for Blood Transfusion meeting in Macao SAR, China

...nd animals. The 2006 National CJD Surveillance Unit report concluded that "the incidence of vCJD may increase again, particularly if different genetic subgroups are found but with longer incubation periods". Abnormal prion proteins are an essential component of vCJD infectivity and may be the only component. T...

Favrille Announces Results from Phase 3 Registration Trial of Specifid in Patients with Follicular B-Cell Non-Hodgkin's Lymphoma

...pecifid plus Leukine(R) (sargramostim, GM-CSF) following Rituxan, compared to the control arm, placebo plus Leukine following Rituxan. Analysis of all subgroups also did not show any significant differences in primary or secondary endpoints when adjusted for prognostic factors. The safety profile was compara...

ProMetic to obtain controlling stake in Pathogen Removal and Diagnostic Technologies Inc.

...nd animals. The 2006 National CJD Surveillance Unit report concluded that "the incidence of vCJD may increase again, particularly if different genetic subgroups are found but with longer incubation periods". Abnormal prion proteins are an essential component of vCJD infectivity and may be the only component. T...

On the trail of rogue genetically modified pathogens

...d viruses. The tool clusters the artificial vector sequences into different subgroups based on shared sequence; these shared sequences were then compared with th...presence of natural sequences using a microarray. Further tests showed that subgroups of candidate DNA signatures are far more likely to match unseen artificial ...

Ortho Biotech Statement On JAMA Publication Regarding Erythropoiesis-Stimulating Agents

...database of more than 15,000 patients treated in various clinical studies, which should inform the benefit:risk profile of ESAs by identifying patient subgroups that would benefit from further study. VTEs Vascular thrombotic events (VTEs) are a well-recognized risk of ESA treatment and are prominently refl...

ProMetic announces scale-up of prion removal resin in plasma product for biopharmaceutical use

... a minimum and the 2006 National CJD Surveillance Unit report stated that "the incidence of vCJD may increase again, particularly if different genetic subgroups are found but with longer incubation periods". About ProMetic Life Sciences Inc. ProMetic Life Sciences Inc. ("ProMetic") (http://www.prometic.co...

The Lancet Publishes Vasogen's ACCLAIM Results

...hile the ACCLAIM study did not meet its primary endpoint for the intent-to treat-population, this primary endpoint was met for two large pre-specified subgroups of patients. In the trial, Celacade was shown to significantly reduce the risk of death or cardiovascular hospitalization by 39% in the subgroup of 68...

ProMetic and MacoPharma announce successful completion of P-Capt(R) prion reduction filter clinical studies

... a minimum and the 2006 National CJD Surveillance Unit report stated that "the incidence of vCJD may increase again, particularly if different genetic subgroups are found but with longer incubation periods". About ProMetic Life Sciences Inc. ProMetic Life Sciences Inc. ("ProMetic") (http://www.prometic.co...

Vasogen and Grupo Ferrer Announce Initial Roll-out of Celacade - New Therapy for Chronic Heart Failure

...he international ACCLAIM trial, Celacade was shown to significantly reduce the risk of death or cardiovascular hospitalizations in large pre-specified subgroups of patients with chronic heart failure, including NYHA Class II patients, where risk was reduced by 39%, and NYHA Class II to IV patients with no prio...
subgroups in Biological Dictionary

Transcapsidation

... This transcapsidation approach consisted of the transfection of pairwise ... Transcapsidation between subgroups A and B generated reduced the viral titer at ... Alert me to new issues of the journal. Download to citation manager. Reprints and ... This transc...

G1 phase

...h a G1 phase amount of DNA. ... (10 , 11) also showed that cyclin B1 accumulated at the G1 phase in human leukemic cell lines. ... sort subgroups in the G1 phase , the cells were first labeled ... G1 phase is the first gap (G) between the activity of cell division in mitosis .....

Deuterostome

...series. Evaluating hypotheses of deuterostome phylogeny and chordate evolution with new ... evolutionary relationships among deuterostome subgroups by obtaining nearly ... The deuterostome phyla include Echinodermata, Hemichordata and Chordata. ... Most previous hypotheses of deuterostome ...
Other Tags
(Date:4/17/2014)... April 17, 2014 EcoHealth Alliance, a nonprofit organization ... published a comprehensive review today examining the current state ... The review calls for improved global surveillance strategies to ... recent outbreak of Ebola in West Africa that has ... of Guinea and Liberia. According to the World ...
(Date:4/17/2014)... NEW YORK (17 April 2014) Population Council scientists and ... is safe, stable, and can prevent the transmission of ... and rectum in animals: HIV, herpes simplex virus 2 ... provides the first data that the gel is effective ... of efficacy in the vagina against all three viruses ...
(Date:4/17/2014)... is less than 40 years away from a food ... governments, according to a top scientist at the U.S. ... human history, food production will be limited on a ... energy," said Dr. Fred Davies, senior science advisor for ... become as politically destabilizing by 2050 as energy issues ...
(Date:4/17/2014)... Johnston, whose work has transformed cancer care in Northern ... European Academy of Cancer Sciences., The Academy, which was ... highly distinguished oncologists and cancer researchers which aims to ... Europe. , Professor Johnston, whose leadership has seen cancer ... of the UK league table to near the top, ...
(Date:4/16/2014)... , PHOENIX, Ariz. April 15, 2014 The ... Arizona philanthropists at their annual Founders Dinner for their ... cancer. The event took place March 28 in Scottsdale. ... & Catherine Ivy Foundation, received TGen,s John S. McCain ...
Breaking Medicine News(10 mins):Health News:Re-emergence of Ebola focuses need for global surveillance strategies 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 3Health News:Animal study provides first evidence that gel can prevent multiple virus transmission in vagina/rectum 2Health News:Food shortages could be most critical world issue by mid-century 2Health News:TGen honors Catherine Ivy and Craig Jackson with Leadership; Collaborative Spirit awards 2
(Date:4/17/2014)... A drug under clinical trials to treat tuberculosis could ... that act against various bacteria, fungal infections and parasites, ... of Illinois chemists and collaborators. , Led by U. ... the different ways the drug SQ109 attacks the tuberculosis ... other pathogens from yeast to malaria and how ...
(Date:4/17/2014)... 2014. Kessler Foundation has been named awardee of ... Department of Defense Spinal Cord Injury Research Program. ... the randomized, double-blinded, controlled, multi-site clinical trial, which ... strength after spinal cord injury. Dr. Forrest is ... at Kessler Foundation. Two additional sites will participate ...
(Date:4/17/2014)... Down syndrome - or trisomy 21 - is the ... from a chromosomal abnormality where cells of affected individuals ... the human genome). A study conducted by Stylianos Antonarakis ... and Development at the University of Geneva (UNIGE) Faculty ... on how the extra chromosome 21 upsets the equilibrium ...
Breaking Biology News(10 mins):Multitarget TB drug could treat other diseases, evade resistance 2Kessler Foundation awarded Department of Defense grant for spinal cord injury research 2Trisomy 21: How an extra little chromosome throws the entire genome off balance 2Trisomy 21: How an extra little chromosome throws the entire genome off balance 3
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