Enzyme shown to help protect genomic stability
Genomes throughout the animal kingdom and beyond are characterized by extensive segments that are inactive, lengthy stretches of DNA containing multiple genes that are closed to gene transcription. Scientists believe one reason for this broad gene silencing is the vital need for genomic stability, for protection against unwanted recombinations of genetic material or other disruptions of the genom...A bug's life: Exceptional genomic stability yet rapid protein evolution in a carpenter ant mutualist
The recent surge in the number of microbial genome sequences available to the scientific community is allowing researchers to address interesting ecological questions and to observe how various genomic, evolutionary, and ecological forces interact to define an organism's role in the environment. Today, Dr. Jennifer Wernegreen's group from the Marine Biological Laboratory presents new data that su...'Signature' of chromosome instability predicts cancer outcomes
Microscopic examination of tumor specimens cannot always predict a cancer's aggressiveness, leading to increased interest in molecular approaches to diagnosis. Now, researchers in the Children's Hospital Informatics Program (CHIP) at the Harvard-MIT Division of Health Sciences and Technology report that a genetic profile indicating chromosomal instability -- an increased tendency to develop chrom...Stability of mRNA/DNA and DNA/DNA duplexes modulates mRNA transcription
The distribution of the four nucleotides along the DNA sequence encodes the genetic information in living systems. However, do nucleic acids possess other attributes that contribute to their biological functions? Recent work of a team led by Stoyno Stoynov, working at the Bulgarian Academy of Sciences, suggests that thermodynamic stability of DNA/DNA and RNA/DNA duplexes influences mRNA transcrip...Keeping the body in sync -- The stability of cellular clocks
A study in Switzerland uses the tools of physics to show how our circadian clocks manage to keep accurate time in the noisy cellular environment. In an article appearing March 13 in the journal Molecular Systems Biology, researchers from the Ecole Polytechnique Federale de Lausanne demonstrate that the stability of cellular oscillators depends on specific biochemical processes, reflecting...Chemical Stability of Disposables
Disposables such as Eppendorf Tubes and pipette tips are frequently exposed to chemical reactions and they must withstand the various kinds of stress and strain encountered in everyday laboratory work (such as centrifuging and autoclaving). The stability level of these products is largely determined by the materials fr...Chemical Stability of the Brinkmann Bottletop Dispenser and the Brinkmann Bottletop Buret
Bottletop Dispenser and the Brinkmann Bottletop Buret Bottletop dispensers are used in the lab for dispensing a wide range of different solvents from glass or stainless steel containers. These dispensers have to meet various requirements. For example, they must not give...New study reveals potential instability in stem cells
A new study in the magazine claims that human embryonic stem cells, one of the few cel...Bio-Anchor® Shoulder Instability Repair System
Description:The Bio-Anchor implant is molded from Poly (L-Lactic Acid) material which has a long-term absorption rate to insure secure fixation throughout the healing process. The Bio-Anchor nearly eliminates implant removal complications because it is absorbed into the tissue or can easily be over-drilled. The ribbed, press-fit anchor design allows for accurate placement and comes pre-threaded with a sing...Microsatellite Instability (MSI) for Hereditary Nonpolyposis Colorectal Cancer
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...