Powe Award supports research on how enzymes enable the pathogenicity of 2 human disease organisms
Using modern biology techniques, Sobrado's group is the first in the world to obtain recombinant functional siderophore hydroxylases from M. smegmatis
(a model organism of M. tuberculosis ) and A. fumigatus . "We have been able to obtain highly active enzymes with FAD bound; this will allow us to...
NHGRI aims to make DNA sequencing faster, more cost effective
...lpha-hemolysin or artificial pores in inorganic materials. This team will use protein-engineering to tailor an alternative protein pore, Mycobacterium smegmatis
porin A (MspA), for nanopore sequencing.
"$100,000 Genome" Grants
NHGRI's "Near-Term Development for Genome Sequencing" grants will support re...
Pitt phage hunter takes on tuberculosis
...issue of Cell, Hatfull and Jacobs described how M. smegmatis
forms a drug-resistant coating called a biofilm. ...he researchers made this discovery by infecting M. smegmatis
with a bacteriophage nicknamed the "Bronx Bomber,"...this occurred because the phage had disrupted a M. smegmatis
gene called groEL1-which has a nearly identical co...