Powe Award supports research on how enzymes enable the pathogenicity of 2 human disease organisms
... us." Using modern biology techniques, Sobrado's group is the first in the world to obtain recombinant functional siderophore hydroxylases from M. smegmatis (a model organism of M. tuberculosis ) and A. fumigatus . "We have been able to obtain highly active enzymes with FAD bound; this will allow us to...NHGRI aims to make DNA sequencing faster, more cost effective
...lpha-hemolysin or artificial pores in inorganic materials. This team will use protein-engineering to tailor an alternative protein pore, Mycobacterium smegmatis porin A (MspA), for nanopore sequencing. "$100,000 Genome" Grants NHGRI's "Near-Term Development for Genome Sequencing" grants will support re...Pitt phage hunter takes on tuberculosis
...issue of Cell, Hatfull and Jacobs described how M. smegmatis forms a drug-resistant coating called a biofilm. ...he researchers made this discovery by infecting M. smegmatis with a bacteriophage nicknamed the "Bronx Bomber,"...this occurred because the phage had disrupted a M. smegmatis gene called groEL1-which has a nearly identical co...