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Sleepiness in Medical News

Cephalon Announces the Availability of NUVIGIL for the Treatment of Excessive Sleepiness Associated with Treated Obstructive Sleep Apnea, Shift Work Disorder and Narcolepsy

NUVIGIL Launch Enhanced by Robust Patient Access Programs FRAZER, Pa., June 1 /PRNewswire-FirstCall/ -- Cephalon, Inc. (Nasdaq: CEPH ) today announced that NUVIGIL(R) (armodafinil) Tablets [C-IV], a longer-lasting formulation of modafinil, is now available. NUVIGIL is indicated to improve ...

Study finds that using wakefulness tests to detect daytime sleepiness in drivers may be unreliable

Westchester, Ill. A study in the Feb. 15 issue of the Journal of Clinical Sleep Medicine shows that a 40 minute protocol for the Maintenance of Wakefulness Test (MWT40) is superior to a 20-minute protocol (MWT20) at detecting excessive daytime sleepiness (EDS) in adults who may be unable to main...

Vanda Pharmaceuticals' VSF-173 Excessive Sleepiness Phase II Clinical Trial Suggests Wake-Promoting Properties

ROCKVILLE, Md., Oct. 30 /PRNewswire-FirstCall/ -- Vanda Pharmaceuticals Inc. (Nasdaq: VNDA ), a biopharmaceutical company focused on the development and commercialization of clinical-stage product candidates for central nervous system disorders, today announced top-line results from the Compa...

New tool to assess excessive daytime sleepiness in adolescents published in JCSM

WESTCHESTER, Ill. A study published in the October 15 issue of the Journal of Clinical Sleep Medicine (JCSM) features the Cleveland Adolescent Sleepiness Questionnaire (CASQ), a new self-completed instrument to measure excessive daytime sleepiness in adolescents. The study, led by James C. Sp...

Changes in narcoleptics' skin, core body temperatures affect their vigilance and sleepiness

WESTCHESTER, Ill. In healthy people, both sleepiness and vigilance show a relationship with core body temperature and skin temperature. When core body temperature is high during the daytime, skin temperature is low, which translates into optimal vigilance. Conversely, when core body temperature...

Evotec Reports Positive Top-Line Results in Phase II Study With EVT 201 in Elderly Insomniacs With Daytime Sleepiness

Statistical Significance in Primary and Key Secondary Endpoints at Both Doses Data Confirm Robust Sleep Onset and Sleep Maintenance Effects Seen in the First Phase II Study in the Adult Population HAMBURG, Germany and OXFORD, England, October 16 /PRNewswire-FirstCall/ -- Evotec AG (Frankfurt...

Study: Modafinil is effective in treating excessive sleepiness

WESTCHESTER, Ill. A study published in the October 15 issue of the Journal of Clinical Sleep Medicine (JCSM) finds that modafinil is well-tolerated in the treatment of excessive sleepiness associated with disorders of sleep and wakefulness such as shift work sleep disorder, obstructive sleep apn...

Mystery Behind Sleepiness After the Meal Revealed

According to research taking a siesta after a heart meal is quite natural, as scientists have discovered that the brain cells stop producing signals after a meal//. This new discovery could pave way for treating obesity and eating disorders as well as understanding levels of consciousness. ...

Self-Applied Acupressure May Reduce Sleepiness And Increase Alertness During Class Hours

Whether it's triggered by the monotone of an instructor or insufficient rest the night before, students at all ages and grade levels sometimes have trouble staying awake in class. Researchers have now found a way to combat the sleepiness // and to keep students awake during class, and it doesn't ha...

The Link Between Eye Disease And Sleepiness

Recent research shows that people who have optic nerve damage are at increased risk for sleep disorder.// The study involved 25 people with visual impairment. The participants had their sleep-wakefulness cycles followed for 14 days, and their results were compared with those of 12 young subject...
Sleepiness in Medical Technology

Cephalon Submits NUVIGIL Supplemental New Drug Application for the Treatment of Excessive Sleepiness Associated with Jet Lag Disorder

FRAZER, Pa., June 30 /PRNewswire-FirstCall/ -- Cephalon, Inc. (Nasdaq: CEPH ) today announced that it has submitted a supplemental New Drug Application (sNDA) to the U.S. Food and Drug Administration (FDA) requesting approval of NUVIGIL(R) (armodafinil) Tablets [C-IV] for the indication of impro...

Jazz Pharmaceuticals and UCB Announce Second Phase III Study of Sodium Oxybate in Patients With Fibromyalgia Meets Primary Endpoints

... is the active ingredient in XYREM(R), approved by the FDA and marketed by Jazz Pharmaceuticals in the U.S. for the treatment of excessive daytime sleepiness and cataplexy (the sudden loss of muscle tone) in adult patients with narcolepsy. The American Academy of Sleep Medicine recommends sodium oxy...

Data Suggest Sodium Oxybate Significantly Improves Pain and the Core Symptoms of Fibromyalgia

...action with GABA(B) and GHB receptors. Sodium oxybate is the active ingredient in XYREM(R), approved by the FDA for the treatment of excessive daytime sleepiness (EDS) and cataplexy (the sudden loss of muscle tone) in adult patients with narcolepsy. The American Academy of Sleep Medicine recommends sodium oxyba...

Addrenex Pharmaceuticals Expands Product Pipeline by Licensing New Drug to Treat Narcolepsy

...l potential benefits over currently marketed drugs for narcolepsy, according to Khayrallah. ADX-N05 has shown the potential to treat excessive daytime sleepiness as well the associated symptom of cataplexy, an abrupt and temporary episode of weakness that can result in collapse. ADX-N05 also exhibited the poten...

Cephalon Announces Positive Results from a Phase Three Study of NUVIGIL in Jet Lag Disorder

...ial of NUVIGIL(R) (armodafinil) Tablets [C-IV] as a treatment for excessive sleepiness associated with jet lag disorder. Based on these findings, Cephalon(R) wil...efficacy and safety of NUVIGIL as a potential treatment for acute excessive sleepiness associated with jet lag disorder were evaluated over the course of three da...

Cephalon Announces Positive Results From a Phase Two Study of NUVIGIL in Bipolar Depression

...NUVIGIL, the longer-lasting isomer of modafinil, in the third quarter of 2009. NUVIGIL is indicated to improve wakefulness in patients with excessive sleepiness associated with treated obstructive sleep apnea (OSA), shift work sleep disorder, also known as shift work disorder (SWD), and narcolepsy. NUVIGIL is...

Jazz Pharmaceuticals, Inc. Completes Enrollment in Second of Two Phase III Clinical Trials of Sodium Oxybate to Treat Fibromyalgia

...action with GABA(B) and GHB receptors. Sodium oxybate is the active ingredient in XYREM(R), approved by the FDA for the treatment of excessive daytime sleepiness (EDS) and cataplexy (the sudden loss of muscle tone) in adult patients with narcolepsy. The American Academy of Sleep Medicine recommends sodium oxyb...

Jazz Pharmaceuticals and UCB Announce Positive Phase III Results for Sodium Oxybate (JZP-6) in Fibromyalgia

...action with GABA(B) and GHB receptors. Sodium oxybate is the active ingredient in XYREM(R), approved by the FDA for the treatment of excessive daytime sleepiness (EDS) and cataplexy (the sudden loss of muscle tone) in adult patients with narcolepsy. The American Academy of Sleep Medicine recommends sodium oxyba...

Jazz Pharmaceuticals, Inc. Announces Final Patient Has Completed Phase III Clinical Trial of Sodium Oxybate to Treat Fibromyalgia

...ials. Sodium oxybate is the active ingredient in Xyrem(R), a Jazz Pharmaceuticals product approved by the FDA for the treatment of excessive daytime sleepiness and cataplexy (the sudden loss of muscle tone) in patients with narcolepsy. Sodium oxybate has not been approved for the treatment of fibromyalgia. ...

Phase III Data Show Vanda Pharmaceuticals' Tasimelteon (VEC-162) Significantly Improves Sleep in Patients with Chronic Insomnia

..., which is currently in Phase III for chronic primary insomnia. Vanda's third product candidate, VSF-173, is a compound for the treatment of excessive sleepiness in Phase II. For more on Vanda Pharmaceuticals Inc., please visit http://www.vandapharma.com . Cautionary Note Regarding Forward-Looking Statements...
Sleepiness in Medical Dictionary

Narcolepsy

...he condition is characterized by excessive daytime sleepiness (EDS) in which a person experiences extreme fatig..... the symptoms of narcolepsy ? Excessive daytime sleepiness ... Narcolepsy (NAR-ko-lep-see) is a disorde...rcolepsy affects less than one percent of men ... sleepiness in narcolepsy is not the result of ... cause of ...

Hypnotics

...oscopic and colossal, and ... Hypnotics (sleeping tablets) are widely prescribed for insomnia, or difficulty in getting to ... Hypnotics cause sleepiness and are used as a short term ... Hypnotics and anxiolytics should therefore be reserved for short courses to ... Hypnotics and anxiolytics may...

Hypnosis

...es usually induced by a procedure known as a hypnotic induction, which is commonly composed of a series of repetitive instructions of relaxation and sleepiness .... Promotes accelerated human change technologies including hypnosis , neural linguistic programming (NLP), and huna. Includes hypnosis FAQ. ...

Hypnotic

...es usually induced by a procedure known as a hypnotic induction, which is commonly composed of a series of repetitive instructions of relaxation and sleepiness .... hypnotic adj. Of or relating to hypnosis. Of or relating to hypnotism. Inducing or tending to induce sleep; soporific: read the bedtime sto...

Drowsiness

...and tests, as well as links to related news and features. Drowsiness - Overview, Drowsiness refers to feeling abnormally sleepy during the ... sleepiness - during the day; Hypersomnia; Somnolence. Definition of Drowsiness : ... Compare Cheap Prices for Drowsiness at NexTag.com. Find Great Bargain...

Cocaine withdrawal

...thdrawal symptoms affect people accustomed to regular cocaine use who either ... Cocaine withdrawal is the fatigue, anxiety, agitation or sleepiness experienced ... People experiencing cocaine withdrawal often attempt to self-medicate with ... Crack cocaine withdrawal information provid...
Sleepiness in Biological News

First biomarker for human sleepiness identified in fruit flies

Scientists have identified the first biochemical marker linked to sleep loss, an enzyme in saliva known as amylase, which increases in activity when sleep deprivation is prolonged. Researchers hope to make amylase the first of a panel of biomarkers that will aid diagnosis and treatment of sleep d...

Genetic study confirms the immune system's role in narcolepsy

... protein's abnormal activity and prevent the onset of the disorder," says Dr. Mignot. Current treatments such as stimulant drugs for combating daytime sleepiness and antidepressants for cataplexy are only able to control symptoms, and do not address the underlying loss of hypocretin cells. It is important t...

Journal Sleep: Insomniacs are more likely to report a family history of the sleep disorder

...nt sleep problem reported in first-degree relatives, followed by sleep apnea (4.6 percent), restless legs syndrome (2.6 percent) and excessive daytime sleepiness (2.4 percent). The subjects mother (19.7 percent) was the most frequently afflicted first-degree relative with insomnia, followed by sister (11.1 per...

Extended wakefulness, combined with alcohol, severely impairs driving performance

...han did a BAC of 0.05 percent in a rested state. In addition to alcohol, sleepiness also increases the risk of road crashes. It is estimated that 15 to 30 per...ugh there are conclusive data regarding the separate effects of alcohol and sleepiness on driving, in real-life situations it is common for these two conditions t...

Alcohol and sleep restriction can affect young men's alertness and driving performance

...tion increased significantly when sleep restriction was combined with the higher dose alcohol. This combination also resulted in a greater subjective sleepiness and negative driving performance ratings compared to control or sleep restriction alone. The ability to keep the car in the middle of the lane is c...

Longer treatment benefits sleep apnea patients

...ted for daytime symptoms such as excessive daytime sleepiness using two widely accepted assessment tools, and fo...n Hours of CPAP Use and Achieving Normal Levels of sleepiness and Daily Functioning," is published in the June i...night. The researchers found that although daytime sleepiness could be improved after 4 hours to 6 hours a night...

Individual differences in a clock gene predict decline of performance during sleep deprivation

... out that this early-morning period corresponds to stretches of time when shift workers struggle to stay awake, during which many accidents related to sleepiness occur. But the scientists also emphasize that the new research was conducted in the laboratory, and whether forms of the PERIOD3 gene also predict ind...

Insomnia drug can improve brain function

...at the positive effect was due to zolpidem. "This phenomenon was so reproducible that caregivers used to give her up to three tablets each day without sleepiness as 'side effect,'" the authors state. The researchers systematically assessed the effect of zolpidem on motor and cognitive function and explore...

Sleep disturbances affect classroom performance

... restless, aching legs when trying to fall asleep, difficulty concentrating during the day, snoring every night, a hard time waking up in the morning, sleepiness during the day, and falling asleep in class. "While a series of previously-conducted studies all found that adolescents reporting inadequate slee...

Negative effects of caffeine are stronger on daytime sleep than on nocturnal sleep

...y it should be awake at this time of day," explains Dr. Carrier. "We often use coffee and other sources of caffeine during the nighttime to counteract sleepiness generated by sleep deprivation, jet lag, and shift-work. However, this habit may have important effects when you then try to recuperate during daytime...
Sleepiness in Biological Technology

SEP Signs REGURIN(R) Deal

...erheitsrelevante Leistungen. Geriatrie Forschung 7 (2): 77-83 (1997) [18] Staskin DR, Harnett MD: Effect of trospium chloride on somnolence and sleepiness in patients with overactive bladder. Current Urology Reports 5: 423-426 (2004) [19] Pietzko A, Dimpfel W, Schwantes U, Topfmeister P: Influence...

SleepQuest Tireless in Pursuit of Good Sleep

...nal Commission on Sleep Disorders indicate that nearly half of all Americans have difficulty sleeping. At the same time, the consequences of daytime sleepiness are frequently in the news. SleepQuest is often invited to speak at large corporations, such as UPS and Amgen, to explain the impact poor sleep can ha...

Vanda Pharmaceuticals to Present at the Bank of America 2008 Healthcare Conference

..., which is currently in Phase III for chronic primary insomnia. Vanda's third product candidate, VSF-173, is a compound for the treatment of excessive sleepiness in Phase II. For more on Vanda Pharmaceuticals Inc., please visit http://www.vandapharma.com . ...

SleepQuest Raises Awareness of Sleep Disorders

...ording to the National Sleep Foundation's Sleep in America poll, Americans are often sleepy at work, drive drowsy, and lose interest in sex because of sleepiness due to working an average 9.5 hours per day and another 4.5 hours per week at home. Many may also suffer from Obstructive Sleep Apnea (OSA) and other ...

Vanda Pharmaceuticals Reports Fourth Quarter and Full Year 2007 Results

...isorders, which is currently in Phase III for chronic insomnia. Vanda's third product candidate, VSF-173, is a compound for the treatment of excessive sleepiness in Phase II. For more on Vanda Pharmaceuticals Inc., please visit http://www.vandapharma.com . NOTE REGARDING FORWARD-LOOKING STATEMENTS This rel...

In response to a New England Journal of Medicine article published yesterday and subsequent media coverage, Eli Lilly and Company issued the following statement:

...ng. Patients taking Cymbalta may experience dizziness or fainting upon standing. The most common side effects of Cymbalta include nausea, dry mouth, sleepiness and constipation. This is not a complete list of side effects. For full Patient Information, visit http://www.cymbalta.com . For full Prescribing...
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