Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
For patients with high-risk breast cancer treated with radical mastectomy and adjuvant chemotherapy, the addition of radiation therapy leads to better survival outcomes with few long-term toxic effects, according to a 20-year follow-up of a randomized trial, which appears in the January 19 issue of the Journal of the National Cancer Institute. The British Columbia randomized radiation the...Opposing fat metabolism pathways triggered by a single gene
Regulating metabolism of fat is an important challenge for any animal, from nematodes to humans. Central players in the regulatory network are the nuclear hormone receptors (NHRs), which are transcription factors that turn on or off a set of target genes when bound by specific lipid molecules. In the premier open-access journal PLoS Biology, Keith Yamamoto and colleagues show that the nuclear hor...Single stem cells from bone heal a broken heart
Myocardial infarction results in irreversible damage to the heart that can cause congestive heart failure. The lasting damage results from the limited ability of the myocardium to regenerate and self-repair. Douglas Losordo and colleagues from Tufts University now document the existence of a previously unrecognized subset of human bone marrow–derived stem cells with therapeutic potency for myocar...Basis for DNA ejection from single phage particles
Studying phage, a primitive class of virus that infects bacteria by injecting its genomic DNA into host cells, researchers have gained insight into the driving force behind this poorly understood injection process, which has been proposed in the past to occur through the release of pressure accumulated within the viral particle itself. Almost all phages (also known as bacteriophages) are f...Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics
A team of scientists led by biophysicist Stuart Lindsay from the Biodesign Institute at Arizona State University has created the first reproducible single molecule negative differential resistor ?and in the process has developed a groundbreaking experimental technique that provides a “roadmap?for designing single-molecule devices based on biochemistry. The findings were presented Feb. 18...DSQ II Single Quadrupole GC/MS from Thermo Scientific
Description:The DSQ II (Dual-Stage Quadrupole) Thermo Scientific (Part of Thermo Fisher Scientific) the world leader in analytical instrumentation, introduces the latest product innovation for laboratory GC/MS the DSQ II. Based on the proven reliability and performance platform of Thermo's DSQ and PolarisQ GC/MS systems, the DSQ II incorporates the new DynaMax XR ion detection system and the DuraBrite ion...EZ-Spread Plating Beads, Single Tubes from Genlantis
Description:EZ-Spread Plating Beads No need for glass rods and potentially hazardous ethanol flaming More uniform spreading and more colonies Two choices of ready-to-use sterile packaging: dispenser bottle for spreading 100 plates or single-use tubes for 50 plating Fastest and easiest way to spread cells on multiple plat...Normal Human Serum-Single Donor from Innovative Research
Description:Normal Human Serum-Single Donor • Human serum is obtained from normal human donors who are found to be negative by a test for Human Immunodeficiency Virus Antigen (s) (HIV-1Ag), Antibodies to Human Immunodeficiency Virus (Anti-HIV 1/2), Hepatitis C Virus (HCV), and Nonreactive for Hepatitis B Surface Antigen (HbsAg) and Non-reactive by a screening test for syphilis. Serum is collected from a...IHC SELECT® DAB KIT SINGLE SPECIES-RAT 150 TESTS from CHEMICON
Description:The IHC Select Immunoperoxidase Secondary Detection System uses biotin-avidin-HRP complexed antibodies to detect rat or goat IgG in the Primary Antibody. The primary antibody binds to specific antigens present in the specimen. Any excess antibody is removed by washing. Next, the Secondary Antibody Reagent (conjugated to biotin) is added and will react with the primary antibody present on the tiss...dotLab System, Single Pump from Axela Biosensors
Description:The dotLab System brings together two mature, well-understood technologies: grating-based light diffraction and immobilized capture surfaces. This combination produces a sensitive and very simple technique for the detection of molecular binding events without the use of fluorescent labels. Protein-specific capture molecules are immobilized on the dotLab Sensor surface in eight distinct l...Purified Single-Stranded M13 DNA for Automated Sequencing
A streamlined and reliable method to obtain high-quality single-strandedDNA Stratagene M13 DNA purification kit allowseasy, quick, and reliable purification of bacteriophage single-stranded DNA. Theyield of single-stranded DNA recovered from phage lysa...Detect Single Nucleotide Sequence Changes with Mx4000 Molecular Beacon Allelic Discrimination Kits
Allelic discrimination kits with excellent specificity, sensitivity, andassay throughput Stratagene Because of their unique hairpin conformation, molecular beacon probes canrecognize single base differences, making them ideal for mutation detection andallelic discrimination. Base...Genotyping Single Nucleotide Polymorphisms with Molecular Beacons
Stratagenes custom molecular beacon synthesis assists in detecting SNPsquickly and easily University of Colorado Health Sciences Center, Denver, Colorado to detect a single nucleotide polymorphism (SNP) in a region of c...XL10-Gold Cells Supplied in New Single-Reaction Format
solopack Gold cells reduce the time and effort needed fortransformationswithout compromise! Anna Waesche Jonathan Goodwin Amy Duncan BruceJerpseth Alan Greener Stratagene strain* in an easy-to-use, single-reaction format thatyield th...Fluorescence-Based Single-Tube Assays to Rapidly Detect Human Gene Mutations
Xiuyuan Hu Beti Belachew Lingyu Chen HaoqiangHuang Jason Zhang Stratagene can distinguish human DNA specimens that differ by a few nucleotides or only asingle nucl...Single gene analysis for diagnosis of a range of blood disorders
A single mutation that causes a number of blood disorders ahs been found out .This may lead to a more accurate diagnosis//, according to a new study. Researchers were able to develop a diagnostic test, which could pinpoint a gene mutation found in most patients with myeloproliferative blood disorders. These disorders are characterized by an overproduction of blood cells and can cause hem...Single drug for bipolar disorder
Researchers have pointed out that on a short term a single drug may be used to treat both the phases of bipolar disorder //. Bipolar disorder is a psychotic disorder characterized by successive feelings of elation and depression. Also known as manic-depressive illness that affects 3 to 4 5 of the global adult population. This is a chronic condition and most of the sufferers have multi...Treating Testicular Cancer With A Single Dose Of Chemotherapy
Researchers now say that a one-day treatment with the anticancer drug carboplatin is as effective// and less toxic than three weeks radiation therapy for a type of testicular cancer, according to results of a recent study. For the last 50 years standard care for stage 1 seminoma—a cancer of the testes—has been surgical removal of the cancerous testicle (hemi-castration) followed by thr...Decreasing Multiple Births By Single Embryo Transfers
Researchers say women opting to undergo a single embryo transfer instead of a double embryo transfer during in vitro fertilization can decrease the chance of multiple births without substantially lowering live births, // according to a new study. Researchers studied 661 women younger than 36 and compared the two approaches of in vitro fertilization. They also evaluated pregnancy rates re...Successful creation of human embryos from a single parent for the first time
Parthenogenesis refers to reproduction by the development of an unfertilized egg or development of eggs from females without fertilization by spermatozoa. Sounds interesting right? Hang// On! This is not all. Scientists have been successful in creating so-called parthenotes, early-stage embryos that are made from a single egg, without the need for sperm. The researchers have so far create...Single Tantalum Clip (50 Style)
Description:For use with E5381 600 Circling Band (40 style)....Single Plate Molteno Implant (S1)
Description:Long-term biocompatibility is established. Provides a robust and durable drainage system. Preplaced suture holes ensure correct positioning on the globe. Pressure Ridge Molteno Implants have a subsidiary ridge which, when covered by Tenons tissue, acts as a Pressure sensitive biological valve, limiting postoperative hypotony. The range of implants allows the surgeon to choose the drainage area ac...Pressure Ridge Single Plate Molteno Implant (D1)
Description:Long-term biocompatibility is established. Provides a robust and durable drainage system. Preplaced suture holes ensure correct positioning on the globe. Pressure Ridge Molteno Implants have a subsidiary ridge which, when covered by Tenons tissue, acts as a Pressure sensitive biological valve, limiting postoperative hypotony. The range of implants allows the surgeon to choose the drainage area ac...