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serotypes in Medical News

PATH Malaria Vaccine Initiative and Crucell to test new malaria vaccine approach

...rotective against malaria in controlled challenge studies and field studies. Using Crucell's AdVac technology with two different vectorsthe adenovirus serotypes Ad35 and Ad26 as delivery mechanisms, this approach seeks to elicit a protective immune response obtained from delivering the CSP. The safety, immunog...

Wyeth's Prevenar 13* Receives First Approval

...d 23F) are included in Prevenar and six additional serotypes (1, 3, 5, 6A, 7F and 19A) associated with the grea... help protect them from the six additional disease serotypes included in Prevenar 13 Valent. Children aged 7 m...13 may not provide 100% protection against vaccine serotypes or protect against nonvaccine serotypes. ...

EU awards $4 million for pneumonia research

...while vaccination reduces spreading of these seven serotypes it has unfortunately led to appearance of uncommon...rmany and United States for example, the prevalent serotypes are different to those serotypes commonly found in India, which complicates worldwi...

FDA Grants Priority Review Status to Prevnar 13 Marketing Application

... designed to protect against the 13 most prevalent serotypes associated with pneumococcal disease -- COLL...al disease (IPD) and otitis media caused by the 13 serotypes included in the investigational vaccine in childre...ged two months through five years. Seven of these serotypes (4, 6B, 9V, 14, 18C, 19F and 23F) are included in ...

Wyeth Submits Marketing Application to FDA for its 13-Valent Vaccine for the Prevention of Pneumococcal Disease in Infants and Toddlers

... designed to protect against the 13 most prevalent serotypes associated with pneumococcal disease - COLLEG... designed to protect against the 13 most prevalent serotypes associated with pneumococcal disease (PD), the lea...ccine-preventable death worldwide. Seven of these serotypes (4, 6B, 9V, 14, 18C, 19F and 23F) are included in ...

Complete Genomes of All Known Human Rhinoviruses are Published

...l serotypes. The extraordinary genetic diversity of circulating rhinovirus serotypes has prevented the production of a universal vaccine for the common cold. A...thors also saw a high rate of diversity among field samples of the same HRV serotypes in the same geographic area over a short time period, suggesting that rhino...

Genetic Code of Common Cold Cracked

...for a single drug that would be effective against many rhinoviruses, Palmenberg and Liggett agreed. "Drugs have the probability of taking out multiple serotypes at one time," Palmenberg said. Who would develop such a drug? "The most likely scenario is that a small biotechnology company would begin the work,...

New test may help to ensure that dengue vaccines do no harm

...mans, has evolved into four related but independent classes of virus called serotypes (DENV-1, DENV-2, DENV-3 and DENV-4). The frightening aspect of the disease ...t any dengue vaccine must raise protective immunity against all four dengue serotypes simultaneously and equally, and several vaccine candidates have generated u...

Was it the chicken salad or the swim?

...increased risk of Salmonella infection associated with chicken or egg consumption, perhaps because of the limited prevalence of certain Salmonella serotypes in the study area. They also found no association between E. coli O157 infections and ground beef consumption; they speculated that this might relat...

Meningitis Vaccine Seems to Work Like a Charm

...mprehensive study looking at a number of different serotypes [groupings of bacteria within a family] and all ag...rchers also found declines in antibiotic-resistant serotypes not specifically targeted by the vaccine. "Ther...all increases in the rates of meningitis caused by serotypes that are not included in the vaccine," Bennett not...
serotypes in Medical Technology

Intercell Starts a Phase I Clinical Trial for a New Streptococcus pneumoniae Vaccine

...er von Gabain. Although vaccines against Streptococcus pneumoniae are available, they cover only a restricted number of the more than 90 known serotypes and it is essential to pursue new vaccines for distribution in countries with the highest medical need for an effective vaccine against the pathogen. ...

Sanofi Pasteur Dengue Vaccine Enters Pediatric Efficacy Clinical Study

...mmunization with three doses of Sanofi Pasteur's tetravalent dengue vaccine candidate generated a sero-neutralizing antibody response against all four serotypes of the virus responsible for dengue fever in 100 percent of adults who participated in the trial(1). The Sanofi Pasteur dengue vaccine research progra...

Wyeth Submits European Marketing Authorization Application for its 13-Valent Vaccine for the Prevention of Pneumococcal Disease in Infants and Young Children

... PCV13 includes the 13 most prevalent pneumococcal serotypes associated with serious PD. Seven of these (4, 6B... in infants and young children. The six additional serotypes (1, 3, 5, 6A, 7F and 19A) are associated with the ...udies have demonstrated that, for the pneumococcal serotypes common to both vaccines, the immunogenicity of PCV...

U.S. Navy and U.S. Army to Develop Dengue DNA Vaccine Formulated With Vical's Vaxfectin(R) Adjuvant

...ue vaccine containing prM and E genes for all four serotypes of dengue, and formulated with the Vaxfectin(R) ad...cine developed neutralizing antibodies to all four serotypes of dengue one month after the second injection (Da...d. Dengue fever can be caused by any one of four serotypes of dengue virus: DEN-1, DEN-2, DEN-3 and DEN-4. Th...

Rapid Test for Pathogens Developed By K-State Researchers Could Be Used to Detect Diseases Used By Bioterrorists

...an detect as many as 557 genes, making it possible for them to screen for 40 different species of bacteria, 1,200 serotypes of Salmonella, five common serotypes of E. coli, and resistance to the 45 most common antibiotics used to treat human and animal illnesses caused by these pathogens. When a sample is su...

Wyeth Applauds Six Countries Across Europe, and the Middle East, That Recently Announced the Inclusion of the 7-Valent Pneumococcal Conjugate Vaccine (PCV7) in Their Immunization Schedules

...AR is the first and only pneumococcal conjugate vaccine approved to help protect infants and young children against pneumococcal disease caused by the serotypes included in the vaccine(7). References available on request. Wyeth Wyeth is one of the world's largest research-driven pharmaceutical and health...

Wyeth Receives FDA Fast Track Designation for its 13-valent Pneumococcal Conjugate Vaccine for Infants and Toddlers

...umococcal disease (IPD) and otitis media caused by serotypes included in the vaccine. The vaccine includes six new serotypes (1, 3, 5, 6A, 7F and 19A) in addition to the seven...not provide 100 percent protection against vaccine serotypes or protect against nonvaccine serotypes. Wyeth P...

New Data Published in The Lancet Show GSK's ROTARIX(R) Offers Protection Against the Most Common Circulating Rotavirus Types

... derived from the most common human rotavirus strain with the goal of offering protection against the most commonly circulating and emerging rotavirus serotypes by mimicking the protective effects of natural human rotavirus infection," said David I. Bernstein, MD, MA, Director, Infectious Diseases; Gamble Prog...

DOR BioPharma Announces Publication Describing Results of Its Multivalent Botulinum Toxin Vaccine BT-VACC

...n components of the natural toxin) of three of the serotypes of botulinum toxin that cause almost all instances of human disease, namely serotypes A, B, and E, can be combined and delivered via nas... or intranasal vaccine against the three botulinum serotypes that are of greatest concern to human health. Seco...

DOR BioPharma Announces Issuance of European Patent for Its Oral Multivalent Botulinum Toxin Vaccine BT-VACC

... a component of what is known as the heavy chain of each of the A, B, and E serotypes of botulinum toxin. The heavy chain component lacks the region of the toxin... available is an experimental vaccine based on inactivation of a mixture of serotypes of the natural toxins that is given by injection, is not licensed by the FD...
serotypes in Medical Products

ImmunoCard STAT!® EHEC Rapid Test

Description:...hagic Escherichia coli in human specimens. The test is performed on McConkey broth overnight enrichment of fecal specimens and detects all Toxigenic serotypes with 92% sensitivity and 100% specificity. The separate result for Toxin 1 and 2 is useful as the latter is associated to more severe clinical symp...
Company:Meridian Bioscience, Inc.
serotypes in Medical Dictionary

Parainfluenza virus

... Human parainfluenza viruses (HPIVs) are a group of four distinct serotypes of single-stranded RNA viruses belonging to the paramyxovirus family. Clinical features: Human parainfluenza viruses (HPIVs) are second to re...

Parainfluenza

... Human parainfluenza viruses (HPIVs) are a group of four distinct serotypes of single-stranded RNA viruses belonging to the paramyxovirus family. Parainfluenza information including symptoms, diagnosis, misdiagnosis, tre...

Dengue

... Dengue fever and dengue hemorrhagic fever (DHF) are acute febrile diseases, found in the tropics, and caused by four closely related virus serotypes of the genus Flavivirus, family Flaviviridae. It is also known as breakbone... Dengue shock syndrome (DSS), also mistakenly referred to as de...

Breakbone Fever

...ngue fever and dengue hemorrhagic fever (DHF) are acute febrile diseases, found in the tropics, and caused by four closely related virus serotypes of the genus Flavivirus, family Flaviviridae. It is also known as breakbone ... Communicable Disease Fact Sheet, dengue fever ... "Dengue Fe...

Adenovirus

...ldren get it several times ... There are over 50 different Adenovirus serotypes in humans, and they are ... Adenovirus infections often show up as conj...genicity in rodents and in tissue culture ... There are 42 adenovirus serotypes with five new types awaiting classification. ... ...

Adenoviruses

... (90–100 nm), nonenveloped (naked) icosahedral viruses composed of a nucleocapsid and a double-stranded linear DNA genome. There are over 52 different serotypes in humans, which are responsible... Features virus information, symptoms, diagnosis, prevention, and treatment. ... Enteric adenoviruses 40 an...
serotypes in Biological News

New vaccine developed for preventing 'uncommon cold' virus

... with a wide spectrum of illnesses including conjunctivitis, upper respiratory infections, pneumonia and gastrointestinal disease. More than 50 unique serotypes of the virus have been identified, with even more expected to be isolated. Adenovirus outbreaks are difficult to control because the virus can live...

Rapid test for pathogens developed by K-State researchers

... it possible for them to screen for 40 different species of bacteria, 1,200 serotypes of Salmonella , five common serotypes of E. coli , and resistance to the 45 most common antibiotics used to trea...

Tips from the Journals of the American Society for Microbiology

...er. 2008. A tetravalent dengue virus vaccine based on a complex adenovirus vector provides significant protection in rhesus monkeys against all four serotypes of dengue virus. Journal of Virology , 82. 14: 6927-6934.) ...

UC Davis researchers discover how HIV turns food-poisoning into lethal infection

...ents with acquired immune deficiency syndrome (AIDS) in sub-Saharan Africa has led to a dramatic increase in the frequency of non-typhoidal Salmonella serotypes (NTS), the strains of the bacteria that cause acute food-borne disease world wide. Normally, this infection is limited to the intestine, causing gastr...

AIBS to cohost symposium on evolution, disease and human health

...whether widespread use in humans of conjugate vaccines, against a subset of serotypes will result in increased carriage of nonvaccine serotypes (serotype replacement), and if so, what the public health consequences will...

New recommendations against a major opportunistic infection -- cryptococcosis

...gical malignancy (such as lymphoma or chronic leukaemia) in which cryptococcosis is the most serious. The study also demonstrates that between the two serotypes of C. neoformans present in France (A and D), serotype A is associated with a more severe presentation and evolution of the disease. Finally, the pati...

Experimental vaccine protects mice against deadly 1918 flu virus

...onoclonal antibodies that may be used as an antiviral treatment, according to Dr. Nabel. "This technique would be very useful in defining evolving serotypes of flu viruses like H5N1 to develop immune sera and neutralizing monoclonal antibodies that may help to contain pandemic flu," says Dr. Nabel. Th...

Gene therapy for hereditary lung disease advances

...ther the alpha-1 gene had begun to express protein. "As the authors conclude, the results set up the more interesting approach of using other AAV serotypes more suited for muscle delivery as an alternative with the same transgene in the next trial," said Richard J. Samulski, a professor of pharmacology an...

UGA study explains peaks and troughs of dengue epidemics

...gy. "So, for example, one year serotype three is 60 percent of the cases and the next year serotype two is dominant and so on. Epidemics of individual serotypes recur every eight to 10 years, but, at the same time, if you look at all the data together, you see about an average three-year cycle with some season...

Outsmarting the smartie bug

...nd its interaction with our immune system and some serotypes are more likely to be associated with disease." ...will protect children from many of the most common serotypes but monitoring is needed to check whether other serotypes start to cause some disease. It is known that pneu...
serotypes in Biological Technology

New Phase 3 Data Continue to Indicate that Wyeth's Investigational 13-valent Vaccine Has the Potential to Broaden Coverage Against Pneumococcal Disease

... to provide coverage against the 13 most prevalent serotypes associated with pneumococcal disease (PD), the lea...nd the world." Prevenar 13 includes the seven serotypes (4, 6B, 9V, 14, 18C, 19F and 23F) in Prevenar* (Pn...fants and young children as well as six additional serotypes (1, 3, 5, 6A, 7F and 19A) associated with the grea...

Avian Adenovirus Genotyping Diagnostic Service

...ning the type-specific neutralizing epitopes. Due to this interaction with the immune system, the sequence identity between loop regions of different serotypes is low. Using these properties of the virus, it is possible to group together different Fowl Adenovirus strains in 5 (A-E) Genogroups based on the...

Major Adult Vaccine Clinical Trial for Pneumonia Prevention Begins

...nd otitis media caused by Streptococcus pneumoniae serotypes 4, 6B, 9V, 14, 18C, 19F and 23F. The study vaccine includes six serotypes (1, 3, 5, 6A, 7F and 19A), in addition to the seven serotypes included in PREVENAR. The 13-valent pneumococcal c...

South Africa Begins Introduction of PREVENAR into Childhood Immunization Program

...ne which helps protect infants and young children against the seven vaccine serotypes causing the majority of pneumococcal disease worldwide. The South African g...o its use. PREVENAR does not provide 100 percent protection against vaccine serotypes or protect against nonvaccine serotypes. Wyeth Pharmaceuticals Wyeth Ph...

Cyprus and Ireland Add Wyeth's 7-Valent Pneumococcal Conjugate Vaccine (PCV7) to Their National Immunisation Schedules

...and debilitating pneumococcal infections caused by serotypes contained in the vaccine. This includes facilitati...hildren against pneumococcal disease caused by the serotypes included in the vaccine.(7) Wyeth Wyeth is one...e pneumococcal disease Due to any of the seven serotypes present in PCV-7: children In England and Wal...

Maxygen Licenses Dengue Vaccine Technology to sanofi pasteur

...on is currently at risk of dengue infection.(2) To date, efforts to develop a dengue vaccine have been challenged by the existence of four different serotypes of dengue virus, all of which are responsible for the severe form of the disease called Dengue Hemorrhagic Fever. To overcome this challenge, Maxygen ...

Single-cell RT-PCR Analysis of Paramecium Primaurelia with the Eppendorf cMaster RTplusPCR System

...maurelia. G and D label the RT-PCR products of the serotypes G and D. M: 100 bp ladder. ...d D mark the RT-PCR products of the serotypes G and D, and * marks the genomic control ...TplusPCR system, the transcripts of the serotypes D and G were clearly detectable using the one-step...
serotypes in Biological Products

Goat Anti-Salmonella, CSA-1 Polyclonal Antibody, Unconjugated from KPL

Description:...m a serum pool of goats immunized with different strains of Salmonella. This antibody is broadly reactive to Salmonella and recognizes all Salmonella serotypes from ATCC. It has excellent specificity for Group B and D Salmonella based upon the Kaufmann-White scheme. Product is in lyophilized form. Each lot...
Company:KPL
serotypes in Biological Dictionary

Transcapsidation

...... dressing the virion: the transcapsidation of adeno-associated virus serotypes ... This transcapsidation approach consisted of the transfection of pai...... dressing the virion: the transcapsidation of adeno-associated virus serotypes ... This transcapsidation approach consisted of the transfection of pai...

Dengue fever

... Dengue fever and dengue hemorrhagic fever (DHF) are acute febrile diseases, found in the tropics, and caused by four closely related virus serotypes of the genus Flavivirus, family Flaviviridae. It is also known as breakbone... Get the facts on dengue fever causes (virus transmitted by i...

Antigens

...urally these antigens are characterized by a few ... T cells do not recognize polysaccharide or nucleic acid antigens . ... Many different serotypes have one or more of their O or H antigens in common. ... destroys flagellar and fimbrial antigens , while alcohol detaches the flagella. ... Def...
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