Tamoxifen-like drug suggests new ways to selectively block estrogen
The ability of an experimental drug known as GW5638 to change the shape of the estrogen receptor is helping researchers understand why drugs like tamoxifen and raloxifene behave the way they do, simulating the effects of estrogen in some tissues and blocking it in others. The finding indicates that this little-known drug may play an important role in preventing, as well as treating, breast cancer...Selectively blocking inflammatory signals may protect mice from MS
A new way to preserve the cells that surround and protect nerves could lead to new treatments for demyelinating diseases such a multiple sclerosis, a research team reports in the May 10, 2006, issue of the Journal of Neuroscience. The approach grew out of a novel explanation, quickly gaining followers, for the mechanism of nerve damage caused by multiple sclerosis. Instead of concentratin...Cells selectively absorb short nanotubes
DNA-wrapped single-walled carbon nanotubes (SWCNTs) shorter than about 200 nanometers readily enter into human lung cells and so may pose an increased risk to health, according to scientists at the National Institute of Standards and Technology (NIST). The results of their laboratory studies appear in an upcoming issue of Advanced Materials.* Eyed for uses ranging from electronic display...Wiping Out Memories Selectively, is Possible Now
It could be possible to wipe out memories selectively from the human brain. Researchers are now emboldened on this front, as they have been able// to wipe out a single specific memory from brains of rats using a drug, leaving all other recollections intact. If that experiment can be successfully replicated in the case of human beings, it could be possible to help relieve sufferers of...