Engineers use blood's hydrodynamics to manipulate stem, cancer cells
...tish Journal of Haematology paper, King and colleagues show they can take the process a step further by implanting the device in a living rat with the selectin
coating remaining active for 1-2 hours. When the tube was removed, King found hed indeed captured cells straight out of the bloodstream, including con...
MIT works toward novel therapeutic device
...shed by the American Chemical Society.
In the body, P-selectin and other selectin
proteins regulate cell rolling in blood vessels. When P-selectin is present...lanted into the blood stream or appended as a shunt. In addition to PEG and selectin
molecules, the device would also include a therapeutic agent. Such an agent...
selectin in Biological News
Cancer-killing invention also harvests stem cells
... back into the bloodstream. He also realized that selectin
is the adhesive mechanism by which bone marrow ste...ells
Because bone marrow stem cells stick to selectin
surfaces more strongly than other cells, King's gr...luidics, or fluid flow properties, and specialized selectin
Killing Cancer Cells
selectin in Biological Technology