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Scientists seek answers on what activates deadly anthrax spores

Scientists at Wake Forest University Baptist Medical Center and three other institutions are setting out to find what activates the spores in anthrax, the deadly bacterial infection that is back in the news. "A key aspect of anthrax spore biology concerns the germination process through which the dormant spore becomes a reproductive, disease-causing bacterium," explained Al Claiborne, Ph.D...

UCLA scientists transform HIV into cancer-seeking missile

Camouflaging an impotent AIDS virus in new clothes enables it to hunt down metastasized melanoma cells in living mice, reports a UCLA AIDS Institute study in the Feb. 13 online edition of Nature Medicine. The scientists added the protein that makes fireflies glow to the virus in order to track its journey from the bloodstream to new tumors in the animals' lungs. "For the past 20 years, ge...

Researchers seek to discover what really happens when a virus enters the body

A well-respected researcher who is now a chief of an immunology laboratory of the National Institutes of Health (NIH) has rocked the boat in the past few years for the experts in the understanding of the autoimmune system. NIH's Polly Matzinger has developed the "danger model," suggesting that the immune system is more concerned with damage detected on the basis of a biological cell's deat...

Hide and seek: Researchers discover a new way for infectious bacteria to enter cells

French scientists have learned how bacterium, found in soil and water, can be transmitted to humans via undercooked and unpasteur...

Retina adapts to seek the unexpected, ignore the commonplace

Researchers at Harvard University have found evidence that the retina actively seeks novel features in the visual environment, dynamically adjusting its processing in order to seek the unusual while ignoring the commonplace. The scientists report in this week's issue of the journal Nature on their finding that this principle of novelty-detection operates in many visual environments. "Appar...

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Doyle seeks $30M for e-medical record adoption

But will that level of commitment be enough? Doyle, speaking at the east clinic of <a href="http://www.deancare....

The development of a CXCR2 chemokine receptorbinding assay using the LEADseeker Multimodality Imaging System

CXCR2 • GPCR • receptor binding assay • LEADseeker • SPA Imaging Beads Chemo-attractant cytokines (chemokines) are low molecular weight, pro-inflammatory cytokines with potent leukocyte activation and/or chemotactic activity (1). Chemokines are classified into four families (CXC, CC, C, and CX...

Performance of the AMARA HitHunter Chemiluminescence Kinase Assay with the LEADseeker Multimodality Imaging System

AMARA • kinase assay • LEADseeker • chemiluminescence It is predicted that at least 500 kinase and phosphatase enzymes exist, their activities having wide-ranging regulatory responses. Many kinases are part of a signaling cascade in disease pathways such as inflammation and cancer, so identifying modulators of kinase...

The development of a melanocortin MC4 receptor binding assay using the LEADseeker Multimodality Imaging System

Melanocortin • receptor binding assay • LEADseeker • SPA Imaging Beads Pro-melanocortins are present in high levels in the pituitary and are processed into three major peptide hormone fragments: adrenocorticotrophin (ACTH), the melanocyte stimulating hormones, and β-endorphin. The various melanocyte stimulat...

The development of a melanocortin MC5 receptor binding assay using the LEADseeker Multimodality Imaging System

Melanocortin • receptor binding assay • LEADseeker • SPA Imaging Beads Pro-melanocortins are present in high levels in the pituitary and are processed into three major peptide hormone fragments: adrenocorticotrophin (ACTH), the melanocyte stimulating hormones, and β-endorphin. The various melanocyte stimulat...

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More People Seeking Treatment for Depression

Major depression, the leading cause of disability in the United States, affects more than 9 million adults in a given year.Despite advances in treatment options and educational efforts,// depression has been described as underdiagnosed and poorly treated in the US. In fact, a recent study stressed that as many as 8 million Americans with serious mental illness fail to receive adequate tre...

Consumer group seeks Sibutramine ban

A consumer group has petitioned the Food and Drug Administration to ban the prescription diet drug sibutramine. Public Citizen says the drug, sold as Meridia, is associated with 29 deaths, including 19 from// cardiovascular causes such as heart attacks. But obesity experts say it's difficult to determine if people died because of Meridia or because they were obese, which put them at incre...

Diabetics To Seek Mental Counseling To Cope With Stress

Diabetics should make it a point to seek mental counseling. Experts say diabetics under mental distress raise their risk for heart disease // because of unhealthy habits they implement to deal with the stress. The study, which sampled 4,241 diabetics, showed nearly 13 percent of respondents experience psychological symptoms such as stress, depression, anxiety or other emotional problems....

Women may not seek help for pelvic floor disorders

A survey done by the Temple University School of Medicine reported that women who suffer from one or more // pelvic floor disorders often do not report their discomfort or seek medical help. The survey also reports that eventually when they do report to their medical practitioner the problem becomes often complicated and of urogynecological nature. Pelvic floor disorder is a range of d...

People seek reassurance in facemasks following threats of bird flu epidemic

Although there has been an incredible and alarming rise in human cases of bird flu, causing increasing fear of a global pandemic, there seems to be a strong resolve in the scientific community to combat this impending and much // dreaded pandemic. Concern about bird flu has risen since October 5 when scientists from the U.S. Army and the Centers for Disease Control and Prevention repo...

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Neoprobe Phase 2 Lymphoseek Trial Meets Primary Endpoint

DUBLIN, Ohio--(BUSINESS WIRE)--Jun 20, 2007 - Neoprobe Corporation(OTCBB:NEOP), a diversified developer of innovative oncology andcardiovascular surgical and diagnostic products, today announcedpositive preliminary results from a multicenter Phase 2 clinicalstudy of its lead clinical candidate, Lymphoseek(R) (TechnetiumTc99m DTPA-mannosyl-dextran). Lymphoseek is a proprietaryradioactive tar...

Waismann Method Survey Reveals 65 Percent of Women Seeking Opiate Dependency Treatment Are Mothers

BEVERLY HILLS, Calif.--(BUSINESS WIRE)--May 10, 2007 - According toThe Waismann Method 2006 Opiate Dependency Survey 65 percent offemale respondents seeking treatment for opiate dependency have oneor more children. Painkillers such as Vicodin, OxyContin, Percocetand Fentanyl were among the drugs cited. In addition, 35 percent ofthe mothers who reported a dependency said they suffered fromde...