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secrete in Medical News

Human cells secrete cancer-killing protein, UK study finds

Human cells are able to secrete a cancer-killing protein, scientists at the University of Kentucky's Markey Cancer Center have found. Researchers led by Vivek Rangnekar, UK professor of radiation medicine, have determined that the tumor-suppressor protein Par-4, initially thought to be active o...

Researchers Make Stem Cells That Secrete Insulin

Mouse study suggests it could help control diabetes in humans WEDNESDAY, Feb. 20 (HealthDay News) -- Scientists have found a way to convert human embryonic stem (ES) cells into cells that release insulin in response to glucose and ease a diabetes-like condition in mice, a new study sa...

Genes key to staph disease severity, drug resistance found hitchhiking together

... as methicillin. The studies were directed by NIAID senior investigator Michael Otto, Ph.D. In 2007, he and his colleagues found that staphylococci secrete toxins of the phenol-soluble modulin (PSM) family that are primarily responsible for attracting and killing human white blood cells called neutrophils...

DNA-damaged cells communicate with neighbors to let them know they're in trouble

...ammatory process without hampering the activity of p53, which is essential to prevent cancer. It also explains why cancerous tumors are still able to secrete inflammatory signals when p53 has mutated and lost its tumor suppressing capabilities. "Inflammation is a hallmark symptom of cancer," said Rodie...

Lab Study Finds Protein That May Inhibit Cancer Spread

...ns by secreting certain proteins that encourage tumor growth and attract feeder blood vessels. In the new study, they found that non-metastatic tumors secrete a protein called prosaposin that inhibits metastasis by promoting production of factors that block the growth of blood vessels, according to a news re...

Potent metastasis inhibitor identified

...by secreting certain proteins that encourage tumor growth and attract feeder blood vessels. Now, he and his colleagues show that non-metastatic tumors secrete a protein called prosaposin -- which inhibits metastasis by causing production of factors that block the growth of blood vessels. Cells from locali...
secrete in Medical Technology

Lexicon's Drug Candidate LX1032 for Carcinoid Syndrome Receives Orphan Drug Designation From EMEA

...inoid syndrome is a chronic condition caused by metastatic neuroendocrine tumors that usually originate from the gastrointestinal tract. These tumors secrete large amounts of serotonin, which can cause a variety of symptoms including severe diarrhea and abdominal discomfort. Patients with carcinoid syndrom...

CEL SCI Collaborators Demonstrate Novel L.E.A.P.S. Vaccines Immunize Mice Against Tuberculosis Antigens and Suggest Potential to Treat Swine and Other Influenzas

...owed that CEL-SCI's L.E.A.P.S. vaccines can activate and cause human immature dendritic cells from blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell mediated and antibody immune response. These results were obtained fo...

Osprey Pharmaceuticals U.S.A., Inc. Initiates Phase Ib Clinical Trial in IgA Nephropathy

...the most common primary cause of kidney disease and occurs as a result of the deposition of Immunoglobulin A in the kidney. The injured kidney tissues secrete a variety of inflammatory mediators including CCL2. CCL2 in the tissue causes CCR2-expressing leukocytes to become activated and to migrate into the k...

Lexicon Presents Clinical Data on LX1032 for Carcinoid Syndrome at European Neuroendocrine Tumor Society Meeting

...me is a chronic condition that is the result of metastatic neuroendocrine tumors that usually originate from the gastrointestinal tract. These tumors secrete large amounts of serotonin, which can cause a variety of symptoms including severe diarrhea and abdominal discomfort. LX1032 acts to reduce serotonin...

New Study First to Confirm Sandostatin LAR(R) Depot Controls Tumor Growth in Patients With Rare Gastrointestinal Tumors

...Ts with the primary tumor within the midgut, were without curative therapeutic options and had tumors that were functionally active (i.e., tumors that secrete various hormones and bioactive amines, causing symptoms such as diarrhea or flushing) or inactive. The study was sponsored by Novartis. The safet...

Napo Announces Positive Clinical Data Indicating Crofelemer, Could Effectively Treat Cholera

...rapy, the water loss associated with severe cholera results in death for about half of affected individuals. The cholera toxin causes the intestine to secrete watery fluid in volumes far exceeding the intestinal absorptive capacity. Current standard-of-care therapy focuses on rehydration therapy, either intr...
secrete in Medical Products

Follicle-Stimulating Hormone (FSH) Enzyme Immunoassay Test Kit

Description:...Stimulating Hormone (FSH) is intimately involved in the control of the growth and reproductive activities of the gonadal tissues, which synthesize and secrete male and female sex hormones. The levels of circulating FSH is controlled by these sex hormones through a negative feedback relationship. The FSH Qu...
Company:Diagnostic Automation, Inc.
secrete in Medical Dictionary

VIPoma

... VIPoma causes cells in the pancreas to produce high levels of a hormone called ... INTRODUCTION VIPomas are rare neuroendocrine tumors that secrete vasoactive ... Radiofrequency Ablation Has a Valuable Therapeutic Role in Metastatic VIPoma . ... VIPoma ... VIPoma is a very rare type of c...

Urinary casts

...inary casts . Definition: Tubules in the kidneys secrete proteins. ... Urinary casts - Our Lady Of ...inary casts . Definition. Tubules in the kidneys secrete proteins. ... ... out to form little cylindric...inary casts . Definition: Tubules in the kidneys secrete proteins. ... Urinary Casts . Definition. ...

TSH

... TSH stimulates the thyroid gland to secrete the hormones thyroxine (T4) and ... The β (beta) subunit (TSHB) is unique to TSH , and therefore determines its function. ... Describes how t...

Stomach acid test

...To test the ability of cells in the stomach to secrete acid , gastrin may be ... Medical Encyclope...To test the ability of cells in the stomach to secrete acid , gastrin may be ... Decreased levels of ..... test the ability of cells in the stomach to secrete acid , ... The stomach acid test is use...

Squamous cell cancer

... organization. ... While squamous cell carcinomas and other skin cancers are almost always curable ... Squamous cell lung cancer may secrete a substance that may cause abnormalities ... Squamous cell lung cancer usually is diagnosed after the disease has spread. ... If you have ...

Sebaceous glands

... Sebaceous glands are microscopic glands in the skin which secrete an oily matter, called sebum, in the hair follicles to lubricate the ski...fitness, and lifestyle destination. Sebaceous ... Sebaceous glands secrete oil into the hair follicle. ... So, basically, sebaceous glands are s...
secrete in Biological News

Malignant melanoma cells secrete protein required for embryo formation

A Northwestern University research group has discovered that aggressive melanoma cells secrete Nodal, a protein that is critical to proper embryo formation. An article describing this research was published today in the advanced online issue of the journal Nature Medicine. The researchers ident...

A crystal ball for brain cancer?

...whose tumors returned. Explaining what the team saw requires an understanding of how the tumor creates an independent blood supply. Cancer cells secrete a growth factor called VEGF that spurs the growth of new blood vessels to supply the tumor with oxygen and nutrients. Avastin blocks VEGF, essentiall...

American Chemical Society's Weekly Presspac -- June 17, 2009

...lizes genetically modifiable aspects of diatom biology, offering the prospect of "milking" diatoms for sustainable energy by altering them to actively secrete oil products," the scientists say. "Secretion by and milking of diatoms may provide a way around the puzzle of how to make algae that both grow quickl...

Powe Award supports research on how enzymes enable the pathogenicity of 2 human disease organisms

...The level of free iron in humans is lower than the required concentration for these pathogens to survive. To overcome this limitation, these organisms secrete molecules called siderophores to obtain iron from the host. The iron-siderophore complex is then taken by the microbes, increasing the concentration o...

Studies shed light on collapse of coral reefs

...y animals, polyps that exist as genetically identical individuals, and can eat, defend themselves and kill plankton for food. In the process they also secrete calcium carbonate that becomes the basis for an external skeleton on which they sit. These calcified deposits can grow to enormous sizes over long per...

Cocaine: Perceived as a reward by the brain?

... of the drug the person consumed in the past," explained Dr. Leyton. The more cocaine someone has used in his or her lifetime, the more the brain will secrete dopamine during subsequent cocaine use. "It's possible therefore that the intensity of the reward-circuit response is related to increased susceptibil...
secrete in Biological Technology

Lexicon Initiates Phase 2 Clinical Trial of LX1032 in Patients With Carcinoid Syndrome

...inoid syndrome is a chronic condition caused by metastatic neuroendocrine tumors that usually originate from the gastrointestinal tract. These tumors secrete large amounts of serotonin, which can cause a variety of symptoms including severe diarrhea and abdominal discomfort. Patients with carcinoid syndrom...

CEL-SCI Files Patent Application to Support Company's Treatment for More Virulent Strain of H1N1 Swine and Other Influenza Viruses

...h NFID meeting in Baltimore showed that CEL-SCI's L.E.A.P.S. vaccines can activate and cause human blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell mediated and antibody immune response. These results were obtained fo...

Results From Neurotech's NT-501 Phase 2 Retinitis Pigmentosa Studies Demonstrate Consistent Biological Effect on Photoreceptors

...implant that consists of human cells that have been genetically modified to secrete ciliary neurotrophic factor (CNTF). CNTF, a growth factor capable of rescui...oduct, NT-501, consists of encapsulated human cells genetically modified to secrete ciliary neurotrophic factor (CNTF). CNTF is a growth factor capable of resc...

CEL-SCI Presents Data at Prestigious Medical Conference Demonstrating That Its L.E.A.P.S. Technology Stimulates Maturation of Human Blood Cells Into Dendritic Cells Suggesting Potential for Prevention and Treatment of Infectious Disease

...and Pharmacy and colleagues showed that CEL-SCI's L.E.A.P.S. vaccines can activate and cause human blood monocyte cells to become dendritic cells that secrete the IL-12 cytokine. The dendritic cells that result initiate a protective cell mediated and antibody immune response. These results were obtained fo...

Histogen Aesthetics Launches ReGenica Rejuvenation System

...in controlled bioreactors that maintain an embryonic-like environment, including low oxygen and low gravity conditions. During this process, the cells secrete growth factors such as Keratinocyte Growth Factor and Vascular Endothelial Growth Factor, and soluble extracellular matrix proteins such as collagens,...

Life sticks: UC San Diego bioengineer's sticky insights published in journal Science

... function are leg bones and breast acini. Breast acini are hollow spherical objects at the ends of breast ducts that are made of a layer of cells that secrete milk proteins. Breast acini form hollow spheres, according to Engler, because this form maximizes the surface to volume ratio. When pressure builds up...
secrete in Biological Definition

Antigen

...(CD4 + ). Those that are specific for them, get activated, so they start to secrete cytokines . The cytokines then activate cytotoxic lymphocytes T (CTL), an...ity molecules . If cytotoxic CD8 + T cells recognize them, they begin to secrete different toxins that cause the lysis or apoptosis of the infected ce...

Apoptosis

...tive apoptosis, sculpts developing tissues in vertebrates. During vertebrate embryo development, structures called the notochord and the floor plate secrete a gradient of the signaling molecule Sonic hedgehog (Shh), and it is this gradient that directs cells to form patterns in the embryonic neural tube:...

B cell

...roducing antibodies. There are two types of B cells: Plasma B cells secrete antibodies which effect the destruction of antigens by binding to them ...the ELISPOT technique, which can determine the percentage of B cells that secrete any particular antibody. B cells are characterised immunohistochemically ...

Cancer

...cals called carcinogens and free radicals are known to cause mutations. Chronic inflammation may induce malignancy, as neutrophil granulocytes secrete free radicals. Mutations can also be inherited. Inheriting certain mutations in the BRCA1 gene renders a woman much more likely to develop breast...

Digestion

...re are at least four hormones that aid and regulate the digestive system: Gastrin - is in the stomach and stimulates the gastric glands to secrete pepsinogen and hydrochloric acid . Secretion of gastrin is stimulated by food arriving in stomach. The secretion is inhibited by low pH . Sec...

Helper T cell

... Once bound to an antigen, the T H cell proliferates and differentiates into activated T H cells and memory T H cells. Activated T H cells secrete cytokines , proteins or peptides that stimulate other lymphocytes ; the most common is interleukin-2 (IL-2), which is a potent T cell growth f...
secrete in Biological Dictionary

Testes

...ne. ... Gray, Henry. 1918. Anatomy of the Human Body. XI. Splanchnology. 3c. The ... 1143, 1144, 1145)—The testes are two glandular organs, which secrete the semen; ... Cryptorchidism is the absence of one or both testes from the scrotum. ... However, most testes descend by the first year of life...

Seminal vesicles

...and above. ... Each seminal vesicle consists of a single tube, coiled upon itself, and giving ... either of two elongated saclike glands that secrete their fluid contents into the ejaculatory ducts of some male mammals. The two seminal vesicles contribute approximately 60 percent of the fluids pas...

Salivary glands

... The salivary glands in mammals are exocrine glands , glands with ducts, that produce saliva. They also secrete amylase, an enzyme that breaks down starch into glucose. In other organisms such as insects, salivary glands are... Salivary glands produ...

Root cap

... the root cap is the zone of division, and above that is the zone of elongation. ... In the outer cells of the root cap , the golgi bodies secrete a slimy substance ... The root cap arises from the cells in this zone. ... Nature's Way Ginger Root 180 Caps and a full online catalog of...

Plasma cells

...alemma) is the ... 3D structures of proteins associated with plasma membrane of eukaryotic cells ... differentiate into plasma cells that secrete these soluble BCRs, which we now call antibodies. ... of clones of plasma cells secreting antibodies against the ... Protein produced by a ...

Pineal gland

... The pineal gland consists mainly of pinealocytes, but four other cell. Cell (biology) ... main cell s of the pineal gland . They produce and secrete melatonin. ... Eye of the Pineal Gland " ... The Pineal Gland is a small organ shaped like a pine cone (hence its name) ... Greeks believ...
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