MetaChip provides quick, efficient toxicity screening of potential drugs
A large, multisite trial designed to examine the safety and preliminary effectiveness of two candidate topical microbicides to prevent HIV infection has opened to volunteer enrollment. The trial, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, represents a partnership among various research institutions in Africa and the U...Boosting HIV screening can increase survival and is cost effective
Expanded HIV screening can increase patient life span, prevent the spread of the disease, and is cost effective, researchers at Yale, Harvard and the Massachusetts General Hospital report in the February 10 issue of the New England Journal of Medicine (NEJM). The study's findings are part of a two-paper series in NEJM on the value of expanded HIV screening in the United States. The Yale/H...Researchers develop assay that could be applied to drug screening
Using state of the art imaging technology a team from Yale School of Medicine has glimpsed one of the cell's most important 'nano-machines' in action. The work, performed in collaboration with English and French scientists, provides new insight into the machinery cells use to internalize cell surface receptors. All cells traffic protein cargos across their outer membrane, and one of the mo...NIH creates nationwide network of molecular libraries screening centers
The National Institutes of Health (NIH) today announced it is awarding $88.9 million in grants to nine institutions over three years to establish a collaborative research network that will use high-tech screening methods to identify small molecules that can be used as research tools. Small molecules have great potential to help scientists in their efforts to learn more about key biological proces...UT Southwestern researchers develop screening test for cells that activate immune system
UT Southwestern Medical Center researchers are the first to create a large-scale, cell-based screening method that identifies which compounds activate immune-response cells that hold promise for future cancer-fighting vaccines. The new screening technique can scan thousands and even millions of compounds to identify those that activate dendritic cells, which are on constant recon patrol th...Equine TNF alpha ELISA development Kit, Screening Set from Endogen
Description:Endogens Screening Sets contain the basic components and protocol required to develop five colorimetric sandwich ELISA plates for quantitation of a specific protein in 100 l/well of cell culture supernate. Every Screening Set contains Coating and Detection Antibodies, Recombinant Standard (5 individual standards), Streptavidin-HRP, TMB Substrate Solution (one-step) and Stop Solution. Each standar...Fragment-based Screening Services from ActiveSight
Description:ActiveSight, the leading provider of X-ray crystallography services for structure-based drug design, offers fragment-based screening services to its pharmaceutical and biotechnology clients. Fragment-based screening involves the binding of drug-like fragments to the active sites of crystallized protein drug targets, allowing scientists to develop novel, high-affinity inhibitors. Relying on state-...Phage Display cDNA Library Screening Kit from Spring Bioscience
Description:Spring offers a large collection of phage display libraries, human adult tissues, fetal tissuea, cell lines, and mouse tissues. All cDNA libraries are constructed in pHD9 vector. The size of cDNA inserts has been verified to be from 200bp to 1000bp by gel electrophoresis of DNA prepared from the amplified libraries....cAMP[125I] Direct SPA Screening Biotrak Assay from GE Healthcare, formerly Amersham Biosciences
Description:cAMP - [125I] Direct SPA Screening Assay, 5 x 96 wells. SPA.Includes lysis reagents that eliminate lengthy sample extraction procedures and allow direct cAMP measurement (optional use).Range: 1.32-84.28 ng/ml (4-256 pmol/ml).Sensitivity: 0.65 ng/ml (2 pmol/ml).Overnight protocol.Store at 2-8 C. Category: Drug Screening & Cellular Assays, Assays . Specific Shipment: USDA Animal Content....CaspSCREEN Caspase Screening Kit from BioVision
Description:Detects caspase activation by flow cytometry....Innovative Tissue Array Technology for High-Throughput Screening of Gene Expression
Stratagene tissue arrayslides offer further refinement of tissue array technology through optimizedtissue fixation and processing procedures that preserve tissue morphology,antigenicity of pr...Screening of Beer-Spoilage Bacteria Using the LightCycler PCR Workflow System
The new LightCycler foodproof Beer Screening Kit (dedicatedto the detection of beer-spoilage bacteria on theLightCycler Instrument) in combination with the MagNAPure LC DNA III Kit (for the automated isolation of bacterialDNA on the MagNA Pure LC Instrument) offersbr...LightCycler foodproof Beer Screening Kit
Breweries make continuous efforts to ensure the highestquality of their goods. To guarantee the consistency ofproduct quality, the different stages of beer production...Need for Colon cancer screening
Colon cancer should be screened periodically once in 5 years in older people (above 50).The usual test is the fecal occult blood test (FOBT) which looks for traces of blood shed by a tumour, or the sigmoidoscopy - an examination of the lower colon. According to researchers at the Finland Affairs Medical Centre in the US, death rate from colon cancer has been decreased due to the routine screening...DNA biochip for genetic screening
A scientist from the University of Houston has developed a chemical process for building a device that could help doctors predict a patient’s response to drugs or screen patients for thousands of genetic mutations and diseases, all with one simple lab test. The DNA chip is similar to a computer chip but imbedded with DNA molecules instead of electronic circuitry. It is designed to pro...Breast screening among diabetic women
Breast cancer should be detected in early stages in order to prevent it from advancing. Women who have diabetes should go for a mammogram as a routine check up, thereby enabling a thourough screening of breast cancer. //According to a new study there has been decreased detection of breast cancer and henceforth brest screening should be implemented. Researchers at the University of Texas...Screening device for ovarian cancer
According to researchers, a new technique for detecting ovarian cancer at an early stage is demonstrating its potential. Researchers in the US are using cutting-edge technology called proteomics //to differentiate healthy from diseased tissue. Proteomics involves creating a 'fingerprint' of tissue, based upon detecting and analysing the different protein molecules it contains. We already know tha...Fast screening for macular degeneration
According to a new study, researchers are investigating a new technique for mapping the back of the retina and screening for the onset of blindness. Age-related macular degeneration (AMD) is the leading cause of blindness in older people. //A team at the University of Utah now report on a technical advance that could be developed into a rapid screen for AMD among people at risk.They could then be...QuickScreen Pro Multi Drug Screening Test
Description:The QuickScreen Pro Multi Drug Screening Test is a rapid, self-timing, qualitative immunoassay forthe detection of drugs of abuse in urine....Bio-Rad Helix EIA Lupus Screening Kit
Description:The ANA and ENA assays can be used to screen out patients negative for antinuclear antibodies, which are associated with various systemic rheumatic diseases such as Systemic lupus erythematosus (Lupus), Sjgren's syndrome, mixed connective tissue disease, progressive systemic sclerosis, scleroderma, polymyositis, dermatomyositis, and Raynaud's phenomenon. They can also be used in conjunction with...Autoimmunity Screening Panel 1
Description:The ImmunoDOT Autoimmunity Screening Panel 1 is an enzyme immunoassay (EIA) test for screening and detectionof autoantibodies against various specific nuclear antigens (ANA, DNA, SS-A/SS-B, RNP/Sm) in serum, and is usedas an aid in the diagnosis of systemic lupus erythematosus (SLE), mixed connective tissue disease (MCTD), andSjgren's syndrome....RELISA ENA Single Well Screening Kit
Description:The RELISA ENA Single Well Screening Kit is designed to screen patient samples for six of the most common autoantibodies. Each microtiter well is coated with Sm, RNP, SS-A, SS-B, Scl-70 and Jo-1 autoantigens. This allows the laboratory to cost effectively screen out the ENA negative patient samples prior to determining the ENA specificity on any of the company's other RELISA ENA Test Systems. The...West Nile Virus Screening and Diagnostics Technology Emerges In Step with North American Outbreak
WNVis a positive single-stranded RNA flavivirus of about 11 kb. It primarily infe...CombinatoRx to Present Combination High Throughput Screening (cHTS) Data at Upcoming AACR Meeting
CAMBRIDGE, Mass.--(BUSINESS WIRE)--Apr 12, 2007 - CombinatoRx,Incorporated (NASDAQ: CRXX), today announced that posters relatedto its oncology research efforts will be presented at the 98thAnnual Meeting of the American Association for Cancer Research,April 14-18, 2007 in Los Angeles, CA. "Systematic Screening of Targeted Chemical Combinations forCancer Therapy", Heilbut, et.al. (Abstract...