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sarcomas in Medical News

Green Tea, Mushroom Extract Combo Slows Sarcomas

2 Chinese studies show cancer treatment extended survival time in mice TUESDAY, April 8 (HealthDay News) -- A combination of the active ingredients in reishi mushrooms and green tea inhibited the growth of tumors and extended survival time of mice with sarcomas, two Chinese studies sho...

Disparities among patients with extremity soft-tissue sarcomas

A new study reveals significant racial and ethnic differences in the treatment and survival of patients with soft-tissue sarcomas, a rare but dangerous cancer that begins in muscle, fat, blood vessels or other supporting tissue of the body. The findings are published in the March 1, 2008, issue of...

Risk Of Soft Tissue Sarcomas In Hereditary Retinoblastoma Survivors

A study by Ruth A. Kleinerman and his colleagues quantifies the risk of hereditary retinoblastoma survivors developing specific subtypes of soft tissue sarcomas and finds that// this risk persists for decades after the original retinoblastoma diagnosis. The findings published in the January 3 ...

Dignitaries Come Together to Honor Participants in the Team Sarcoma Initiative

...a is a cancer of the connective tissues, such as nerves, muscles and bones. sarcomas account for 15-20% of childhood cancer diagnoses and about 1% of adult canc...es. They are often misdiagnosed and resistant to current treatments. Though sarcomas are rare, they affect hundreds of thousands of people worldwide. Patie...

Women underrepresented in most cancer research

... Non-sex-specific cancers included hematologic (blood-related), gastrointestinal, urinary, lung, nervous system, and head and neck cancers, as well as sarcomas (connective tissuerelated). On average, women constituted 38.8 percent of patients enrolled in a study. Women made up a significantly lower propor...

Women under-represented in most cancer research

... Non-sex-specific cancers included hematologic (blood-related), gastrointestinal, urinary, lung, nervous system, and head and neck cancers, as well as sarcomas (connective tissuerelated). On average, women constituted 38.8 percent of patients enrolled in a study. Women made up a significantly lower propor...

Rexin-G Controls Tumor Growth and Improves Survival in Chemotherapy-Resistant Sarcoma and Osteosarcoma: Phase I/II and Phase II Studies, ASCO 2009

...rmatory trial in the U.S. The Phase I/II study evaluating the safety and efficacy of Rexin-G in chemotherapy-resistant metastatic bone and soft tissue sarcomas (ASCO Annual Meeting 2009, #10513) demonstrated that Rexin-G was well-tolerated with no dose-limiting toxicity. Moreover, Rexin-G exhibited dose-depen...

The Children's Hospital of Philadelphia Recognized as a 'Fertile Hope Center of Excellence'

...ited States. Its large basic and clinical research programs are particularly strong in pediatric neuro-oncology, neuroblastoma, leukemia and lymphoma, sarcomas and cancer survivorship. Of all pediatric institutions, Children's Hospital enrolls the most patients in national clinical trials, working in close co...

Novartis Oncology Launches GIST Alliance™ for Healthcare Professionals Treating Gastrointestinal Stromal Tumors

...orted each year in the United States (1, 2). Approximately 2,500 of these cases are metastatic at diagnosis (3). GISTs are soft tissue sarcomas. sarcomas are difficult to differentiate from other malignancies when they are found within organs; thus, they are frequently misdiagnosed and highly underrepor...

How chemotherapy drugs block blood vessel growth, slow cancer spread

...bicin (Adriamycin), daunorubicin, epirubicin, idarubicin have been used for four decades to treat many types of cancer, including leukemia, lymphoma, sarcomas and carcinomas, The standard method of administration had been to use the highest tolerable dose every few weeks to kill all rapidly growing cells by ...
sarcomas in Medical Technology

New Cancer Treatment Stops Aggressive Sarcomas

NASHVILLE, Tenn., Feb. 25 /PRNewswire/ -- After all standard treatments had failed, a new cancer treatment has stopped the growth of aggressive sarcomas in two recent patients. These results are similar to the new protocol's previous success against several cancers, including melanoma, pancreatic,...

Keryx Biopharmaceuticals, Inc. Announces Positive Preliminary Phase 2 Data on KRX-0401 in Patients with Chemo-Insensitive Rare Sarcoma

...linical activity of KRX-0401 (perifosine) in patients with refractory, rare sarcomas was presented on Saturday, November 3, 2007 at the Annual Meeting of the Co...sine is being evaluated in patients with chondrosarcoma, alveolar soft part sarcomas and extra-skeletal myxoid chondrosarcomas. Patients are being treated with ...

Roche Announces Positive Results in Solid Tumors Using Human Monoclonal Antibody Against IGF-1R (R1507)

...erts. SARC is unique as a clinical trial organization in that its trials at the inception include pediatric and medical patients with sarcoma, because sarcomas affect people of all ages. SARC is a 501c3, non-profit organization that is headquartered in Ann Arbor, Michigan. ...

Positive Results Prompt US National Cancer Institute to Make Gleevec Available To Patients in Post-Surgical Gist Study

...ults will be presented at a forthcoming scientific meeting. Gastrointestinal stromal tumors (GIST) belong to a group of cancers known as soft tissue sarcomas that usually arise from the intestinal tract, with the most common site being the stomach followed by the small intestine. The incidence of GIST is es...

Positive Results Prompt US National Cancer Institute to Make Glivec Available to Patients in Post-Surgical GIST Study

...ults will be presented at a forthcoming scientific meeting. Gastrointestinal stromal tumors (GIST) belong to a group of cancers known as soft tissue sarcomas that usually arise from the intestinal tract, with the most common site being the stomach and followed by the small intestine. The incidence of GIST i...

Clinical Data on ARIAD's Novel mTOR Inhibitor, AP23573, To Be Presented at the ASCO Annual Meeting

...gent AP23573 in patients with soft-tissue and bone sarcomas and initial results from the Phase 2 trial of sing...nitiating our Phase 3 clinical trial in metastatic sarcomas during the third quarter of this year." The s...iation of our Phase 3 clinical trial in metastatic sarcomas in the third quarter of 2007. Forward-looking stat...

AEterna Zentaris Partner Keryx Presents Phase 1 and Phase 2 Results for Anti-Cancer Compound Perifosine at ASCO Meeting

... novel oral alkylphospholipid that targets the PI3K pathway upstream from mTOR by inhibiting the phosphorylation of Akt. Perifosine's activity against sarcomas has now been evaluated in 145 patients enrolled in one of three Phase 1 trials or four Phase 2 trials. Five of these trials have been published. ...

Hyperthermia Plus Chemotherapy Nearly Doubles Disease-Free Survival Compared to Chemotherapy Alone for Sarcoma Cancer Patients

...mpared to patients who received chemotherapy alone. The patients enrolled in this clinical study were very ill, with high-grade (II/III) soft tissue sarcomas and were at significant risk of local failure and metastasis. The patients were randomly assigned to receive either chemotherapy alone or chemotherapy...
sarcomas in Medical Dictionary

Tissue

...efront of the diagnosis and treatment of adult sarcomas of soft tissue , which may arise from any support...... Preoperative irradiation for soft tissue sarcomas of the trunk and extremities in adults. ... saving...loyment opportunities at CTS ... Soft tissue sarcomas are a disease of adulthood, occurring most commo...

Soft tissue

...coma. Get More Information ... Soft tissue sarcomas are malignant (cancerous) tumors that can develop ...mbryonal rhabdomyosarcoma Many soft tissue sarcomas are quite fleshy in appearance. ... The tumor is...ft tissue it resembles. ... Soft tissue sarcomas are cancerous tumors that grow in muscles, fat, jo...

Sarcoma

... tissue. Providing information about, and specialized treatment for, sarcomas and other musculoskeletal tumors. Sarcoma | Cancer.Net - The America...sarcoma is of great concern. ... Includes both soft tissue and bone sarcomas . ... Sarcoma is a cancer of the bony skeleton (ie. the skull, verteb...

Rhabdomyosarcoma

...e extremities composed of anaplastic muscle Describes the fast-growing, highly malignant tumor which accounts for over half of the soft tissue sarcomas in children. Detailed information on rhabdomyosarcoma , including causes, stages, symptoms, diagnosis, and treatment ... Rhabdomyosarcoma is ...

Mammary

...milk ... Based on the development of mammary glands in mouse models, researchers at the ... Pet links,canine cancer feline mammary tumors sarcomas osteosarcoma,dog,cat ... Ninety-nine female dogs with mammary gland carcinomas, no previous therapy, an ... Disorders of the mammary glands...

Leiomyosarcoma

...ody. ... Leiomyosarcoma accounts for 7 to 11 percent of all soft tissue sarcomas among ... Dr. Michael J. Weaver and Dr. John A. Abraham explain the pre...hat it is, causes, symptoms, diagnosis and treatment. Because uterine sarcomas are so rare, it is important for women diagnosed with these types of cance...

Larynx

...f the Larynx : Grand Rounds presentation from the Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine. sarcomas of the Larynx : Grand Rounds presentation from the Bobby R. Alford Department of Otolaryngology-Head and Neck Surgery, Baylor College of Medicine. ...
sarcomas in Biological News

Immunotherapy in high-risk pediatric sarcomas shows promising response

PHILADELPHIA Based on a pilot study in children with sarcoma, researchers at the National Institutes of Health (NIH) believe that immunotherapy could prove beneficial in treating high-risk forms of this cancer. The researchers tested a novel dendritic vaccine as well as a standard flu vaccine...

Study examines risk of soft tissue sarcomas in hereditary retinoblastoma survivors

A study in the January 3 issue of the Journal of the National Cancer Institute quantifies the risk of hereditary retinoblastoma survivors developing specific subtypes of soft tissue sarcomas and finds that this risk persists for decades after the original retinoblastoma diagnosis. The findings em...

GUMC discovery highlights new direction for drug discovery

...for other disorders caused by the interaction between two proteins, and may be especially useful in cancers caused by translocations of genes, such as sarcomas and leukemias, the researchers say. Agents in use now that work against fusion proteins inhibit a single protein to stop intrinsic enzymatic activity;...

Positron emission tomography superior to standard evaluation tools in measuring treatment response

...ter way to predict response so patients would not have to undergo unnecessary treatment or be removed from therapies that were working. Since operable sarcomas are treated before surgery with chemotherapy and radiation, it was the ideal cancer in which to compare PET scanning to CT. CT and MRI scans provi...

Study proposes new theory of how viruses may contribute to cancer

...t. 24 issue of PLoS ONE. Infection with viruses has been linked to many human cancers, including some forms of Hodgkins and non-Hodgkins lymphomas, sarcomas and cancers of the throat and liver. Over the years, scientists have proposed a number of mechanisms to explain this link. One commonly held belief is...

Dealing deadly cancers a knockout punch

...ation, Reolysin®, is active against numerous cancers, including intractable sarcomas and melanomas. Recent studies also indicate that Reolysin works syner...I trial to evaluate intravenous administration of Reolysin in patients with sarcomas that have metastasized to the lung. For patients with deadly soft tissue sa...

Reactivated gene shrinks tumors

...In lymphomas, or cancers of the white blood cells, the cancer cells underwent apoptosis within 1 or 2 days of the p53 reactivation. In contrast, sarcomas (which affect connective tissues) did not undergo apoptosis but went into a state of senescence, or no growth. Those tumors took longer to shrink but ...

New way of tracking muscle damage from radiation

...hese changes at such an early stage may help clinicians predict which patients need an intervention to prevent late damage," Krasin said. Soft tissue sarcomas are cancers that arise in muscles, fat, blood vessels and other soft tissues. Ewing sarcoma is a cancer that arises in the bone or soft tissue, usuall...
sarcomas in Biological Technology

Oncolytics Biotech Inc. Collaborators Present Reovirus Research for Pediatric Sarcomas at AACR Annual Meeting

CALGARY, April 15 /PRNewswire-FirstCall/ - Oncolytics Biotech Inc. (TSX: ONC, NASDAQ: ONCY) announced that a poster presentation by Dr. Anders Kolb of the Nemours Center for Childhood Cancer Research entitled "Radiation in Combination with Reolysin for Pediatric Sarcomas" was presented today a...

FDA Grants Epeius Biotechnologies' Rexin-G a Third Orphan Drug Designation, This Time for the Treatment of Soft Tissue Sarcomas

SAN MARINO, Calif., July 9 /PRNewswire/ -- Epeius Biotechnologies Corporation today announced that Rexin-G has been granted Orphan Drug Designation by the U.S. Food and Drug Administration (FDA) for the treatment of all soft tissue sarcomas. This latest approval is the third clinical indicatio...

Oncolytics Biotech(R) Inc. Collaborators Present Positive Phase II Sarcoma Trial Results at ASCO Annual Meeting

...rim results of a Phase II study of intravenous REOLYSIN(R) in patients with sarcomas metastatic to the lung were presented May 30, 2009 at the American Society ...(Wild-type Reovirus) in the Treatment of Patients with Bone and Soft Tissue sarcomas Metastatic to the Lung" was delivered by Dr. Monica Mita, the study princip...

Oncolytics Biotech(R) Inc.'s Research Collaborators to Present Data on REOLYSIN(R) Clinical Trials at ASCO Conference

... presentation entitled "A Phase II Study of Intravenous (IV) Wild-Type Reovirus in the Treatment of Patients with Bone and Soft Tissue sarcomas Metastatic to the Lung." - Dr. Johann de Bono and colleagues are scheduled to deliver a poster presentation entitled "A Phase I Study o...

Oncolytics(R) Biotech Inc. Completes Patient Enrolment in U.S. Phase 2 Sarcoma Study

...uate the intravenous administration of REOLYSIN(R) in patients with various sarcomas that have metastasized to the lung. A total of 52 patients have been enroll...f intravenous, multiple dose REOLYSIN in patients with bone and soft tissue sarcomas metastatic to the lung. REOLYSIN is delivered intravenously to patients at ...

Oncolytics Biotech(R) Inc. Reports Highlights and Financial Results for 2008

...endpoint in our US multicentre, Phase 2 clinical trial to evaluate the intravenous administration of REOLYSIN in patients with various sarcomas that had metastasized to the lung. We reported that of 33 patients evaluable for response, five had stable disease for more than six m...

Oncolytics Biotech Inc.'s REOLYSIN(R) Exceeds Primary Statistical Endpoint in U.S. Phase 2 Sarcoma Study

...nistration of REOLYSIN(R) in patients with various sarcomas that have metastasized to the lung. "The propo...hat late-stage clinical trials are justified." sarcomas are malignant tumors growing from connective tissu... REOLYSIN(R) in patients with bone and soft tissue sarcomas metastatic to the lung. REOLYSIN(R) is delivered i...

Oncolytics Biotech Inc. Investigators Present Interim U.S. REOLYSIN(R) Phase II Sarcoma Trial Data

...an oral presentation covering the interim results of a U.S. Phase II trial investigating intravenous REOLYSIN(R) in patients with bone and soft tissue sarcomas metastatic to the lung is being delivered today by Dr. Monica Mita of the Institute of Drug Development (IDD), the Cancer Therapy and Research Center ...

Oncolytics Biotech Inc. Collaborators to Present REOLYSIN(R) Clinical Trial

...ral presentations, both entitled "A Phase II Study of Intravenous Reolysin (Wild Type Reovirus) in the Treatment of Patients with Bone and Soft Tissue sarcomas Metastatic to the Lung" at the Chemotherapy Foundation Symposium XXVI, being held in New York from November 4-8, 2008 and also at the Connective Tissu...

Gleevec Receives FDA Priority Review as First Therapy to Reduce Recurrence of Gastrointestinal Stromal Tumors After Surgery

...al stromal tumors (GIST) Gastrointestinal stromal tumors (GIST) belong to a group of cancers known as soft tissue sarcomas. They are the most common sarcomas and can be found most often in the stomach and small intestine. The incidence of GIST is estimated to be 4,500 - 6,000 new cases per year in the US (1...
sarcomas in Biological Definition

Cancer

...rom most frequently occurring to least: neuroblastoma , leukemia , central nervous system, retinoblastoma , Wilms' tumor , germ cell, soft tissue sarcomas , hepatic, lymphomas (such as Hodgkin's disease ), epithelial. Diagnosing cancer Biopsy A biopsy leads to the definitive diagnosis of ...
sarcomas in Biological Dictionary

Tissue

... ... A sarcoma is a type of cancer that develops from certain tissues , such as bone or muscle. ... This document concentrates on soft tissue sarcomas in adults. ... Epithelial tissue covers the whole surface of the body. ... This tissue is specialised to form the covering or lining of all int...
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