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New polysaccharide may help combat multidrug resistance in cancer

In a recent study published in the Journal of Biological Chemistry, scientists report that a molecule previously thought to play a purely structural and inert role in cells is actually involved in multidrug resistance in cancer. Using antagonists for this molecule, the researchers were able to sensitize drug resistant breast cancer cells to chemotherapeutic drug treatment. The research ap...

Fluoride poisoning in China due to clay, not coal

Millions of people in southwest China suffer from potentially-crippling fluoride poisoning because they burn a mixture of clay and coal, say researchers. Because of this belief, last year, the...

Mice lacking social memory molecule take bullying in stride

The social avoidance that normally develops when a mouse repeatedly experiences defeat by a dominant animal disappears when it lacks a gene for a memory molecule in a brain circuit for social learning, scientists funded by the National Institutes of Health's (NIH) National Institute of Mental Health (NIMH) have discovered. Mice engineered to lack this memory molecule continued to welcome strange...

Salk researchers make fast strides towards understanding how our body controls walking

Researchers at the Salk Institute for Biological Studies have identified an important circuit in the spinal cord that controls the speed with which our leg muscles contract and relax. Their findings mark an important milestone in understanding the neural circuitry that coordinates walking movements - one of the main obstacles in developing new treatments for spinal cord injuries. "Knowing...

Microscopic passengers to hitch ride on space shuttle

When space shuttle Atlantis rockets into space later this week, it will take along three kinds of microbes so scientists can study how their genetic responses and their ability to cause disease change. The 'Microbe' experiment, part of the STS-115 space shuttle mission scheduled for launch Aug. 27, will study three common microorganisms -- Salmonella typhimurium, Pseudomonas aeruginosa...

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Reacti-Bind Maleic Anhydride Activated Polystyrene 96-Well plates from Pierce Biotechnology, Inc.

Description:Features Open up new opportunities in ELISA development...
Company:Pierce Biotechnology, Inc.

Acridine Orange hemi(zinc chloride) salt from Sigma-Aldrich

Description:Application: Acridine orange has been used as a fluorescent stain for nucleic acids in agarose and polyacrylamide gels. Acridine orange at a concentration of 120 μM will detect purified DNA in gels with a sensitivity of 25-50 ng per band. It has also been used extensively for cell staining of DNA in apoptosis studies. Special grade: for molecular biology...
Company:Sigma-Aldrich

4',6-diamidino-2-phenylindole, dihydrochloride (DAPI) from Molecular Probes (Invitrogen)

Description:...
Company:Molecular Probes (Invitrogen)

4',6-Diamidino-2-phenylindole dihydrochloride (DAPI) from Sigma-Aldrich

Description:Cell permeable fluorescent minor groove-binding probe for DNA. Binds to the minor groove of double-stranded DNA (preferentially to AT rich DNA), forming a stable complex which fluoresces approximately 20 times greater than DAPI alone. DAPI is several times more sensitive than ethidium bromide for staining DNA in agarose gels. It may be used for photofootprinting of DNA, to detect annealed probe...
Company:Sigma-Aldrich

4',6-Diamidino-2-phenylindole, dihydrochloride (DAPI) from Pierce Biotechnology, Inc.

Description:4',6-Diamidino-2-phenylindole, dihydrochloride (DAPI)...
Company:Pierce Biotechnology, Inc.

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Detect Released Oligosaccharides Using the Eagle Eye II Still Video Imaging System

IIStill Video Imaging System Department of Biology, Delaware State University, Dover, DE II still video system andthe Glyko FAC...

Characterization of Protein Oligosaccharides Using MSn

Andrew S.Weiskopf and Paul Vouros, Northeastern University, Boston, MA David J. Harvey, University of Oxford, Oxford, UK The data presented here can be acquired using the Thermo Finnigan LCQ Series of ion trap mass spectrometers. Introduct...

Femtogram Sensitivity of the Antipsychotic Drugs Raclopride and Ritanserin Using a Varian 1200L LC/MS/MS

Varian, Inc. These two compounds were used to demonstrate low-level sensitivity of...

Strategies to Identify and Confirm Phase I Metabolites of Glyburide Using the 4000 Q TRAP System

In this application note, several different metabolite identification approaches are evaluated for their merits. A comprehensive examination of four Information Dependent Acquisition (IDA) survey modes was performed to illustrate data quality and types of metabolites found. A significant number of metabolites were found with each mode of operat...

Pacific Cycle rides full speed into RFID

The company, which owns such traditional brands as Schwin...

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Polysaccharide

. joined together by glycosidic linkages. They are therefore very large, often branched, molecule...

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Polysaccharides

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Polysaccharide

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Periderm

and <a href="/ ?q=/ Biolo...

Monosaccharides

are simple sugars, having 3 to 7 carbon...

Disaccharides

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Are cancer patients being taken for a ride?

One issue that always raises many uncomfortable questions and more troubling answers is that of drug trials. Drug testing has always been an ethical issue and has kindled a lot of heated arguments for and against it. Recent studies have revealed that cancer victims suffer the most when it comes to drug testing when sometimes very toxic new anti cancer drugs are tested on unsuspecting vict...

Roller coaster takes brain for a big ride!!

Riding roller coasters may increase the risk of developing potentially harmful blood clots on the brain's surface. The Neurological center reported a case of 25 year old healthy male who developed blood clots on the brains surface, known as subdural haematomas, after riding several roller coasters. The symptoms of blood clot includes difficulty in walking, vomiting, changes in m...

Fluoride Found Effective in Osteoporosis

Fluoride, in combination with calcium and vitamin D, increases bone mass and lowers the risk of backbone fractures associated with osteoporosis, researchers report. Fluoride is known to stimulate new bone formation, but concerns about its safety have limited its use in the elderly, according to Dr. Craig D. Rubin from University of Texas Southwestern Medical Center at Dallas, and others w...

Triglycerides Linked To Stroke Risk

Researchers have linked high levels of blood fats called triglycerides to an increased risk of stroke. The findings should encourage physicians to pay closer attention to triglyceride levels.// More effective screening and detection of high blood triglycerides and treatments to modify this stroke risk factor could further reduce the stroke burdens. Doctors have learned that drugs that...

Fluoride proves effective against fractures

Sustained-release sodium fluoride in combination with calcium citrate and vitamin D can safely reduce the risk of fractures and increase spinal bone mass in older women with osteoporosis,// a recent study from the University of Texas Southwestern Medical Center concluded. Our study showed that this combination of therapy safely reduces the risk for fractures by stimulating new bone for...

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Trident Hemispherical

Description:Trident Hemispherical Acetabular Shells are a true hemispherical shape designed to achieve press-fit fixation by under-reaming the acetabulum....
Company:Stryker Corporation

Triglyceride (GPO)

Description:For the quantitative determination of triglycerides in serum. Linearity: 1000 mg/dl....
Company:Horizon Diagnostics, Inc.

Triglycerides Liquid Reagent

Description:Intended for the quantitative determination of triglycerides in serum or plasma. Reaction: endpoint, reaction is complete in five minutes at 37C. Wavelength: 540 nm. Linearity: 1000 mg/dL (11.3 mmol/L). Two vials, liquid reagents....
Company:Hemagen Diagnostics, Inc.

Triglycerides GPO Reagent

Description:Intended for the quantitative determination of triglycerides in serum or plasma. Reaction: endpoint. Wavelength: 520 nm. Linearity: 1000 mg/dL (11.3 mmol/L). Single vial, dry powder reagent....
Company:Hemagen Diagnostics, Inc.

Triglyceride (INT)

Description:Storage temperature: 2 - 8C, linearity: 0 - 700 mg/dL, expected values: 30 - 780 mg/dL. Available with calibrator and number of tests 110....
Company:Cima Scientific

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Lexicon Develops Antibodies That Lower Triglycerides and Cholesterol as Potential New Therapy for Heart Disease

- Publication of New Cardiovascular Target from Lexicon's GeneticResearch - THE WOODLANDS, Texas, July 02, 2007 /PRNewswire-FirstCall/ --Lexicon Pharmaceuticals, Inc. today reported results frompreclinical research demonstrating that antibodies directed to apotential new target, angiopoietin-like protein 4 (ANGPTL4),rapidly lower triglycerides and cholesterol. Research suggests thata mon...

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Triglyceride level

High of 150 or lower is con...

Mucopolysaccharides

Reviewed By : Michael C. Milone, M.D.,...

Debridement

that contain non-living (necrotic) <a href="/ ?q=/ Medicine-Dictionary/ ti...

Chloride

Alternative Names:<B...

Acid mucopolysaccharides

Full ar...