Antiretroviral therapy may prevent excess risk of some cancers in people with HIV
In people infected with human immunodeficiency virus (HIV), highly active antiretroviral therapy (HAART) may prevent most excess cases of Kaposi sarcoma and non-Hodgkin lymphoma, according to a new study in the March 16 issue of the Journal of the National Cancer Institute. Studies of people with acquired immunodeficiency syndrome (AIDS) have reported increased risks of several cancers, in...Study reveals candidate targets for anti-retroviral therapeutics
The increased frequency of drug resistance in isolates of the AIDS virus, HIV, makes identification of new antiviral targets an urgent necessity. Host genes required to support the replication of HIV are a potential source of such novel targets, but relatively few appropriate target genes have been identified in animal cells thus far. A new study, conducted by Dr. Suzanne Sandmeyer and colleagues...Chimp genome reveals a retroviral invasion
It's been known for a long time that only 2% -- 3% of human DNA codes for proteins. Much of the rest of our genomes -- often referred to as junk DNA -- consists of retroelements: genomic elements that are transcribed into RNA, reverse-transcribed into DNA, and then reinserted into a new spot in the genome. Human endogenous retroviruses make up one class of these retroelements. Retroviruses can in...Antiretroviral Therapy May Prevent HIV Transmission From Breastfeeding Mothers To Infants
Two new studies support the hypothesis that combination antiretroviral drug therapy may reduce the risk of mother-to-child HIV transmission through breastfeeding, findings that could have significant implications in the developing world. Researchers in the first study found mothers pass antiretroviral medications on to their breastfeeding infants in concentrations high enough to prevent in...Retroviral resistance gene found
Dr. Stephen Goff and colleagues have identified a novel retroviral resistance gene, called FEZ1, that can mediate a potent resistance to murine leukemia virus, as well as HIV-1, in cell culture. The researchers found that the high level of FEZ1 expression in a specific laboratory rat cell line caused a significant block to retroviral infection ?retroviruses were able to enter the host cells and s...Functional Cloning Using ViraPort Retroviral cDNA Expression Libraries
Retroviral libraries with high-titer efficiency and larger insertpotential ViraPort Retroviral cDNA Expression Libraries Katherine Felts Kim Zaharee Latha Sundar JamieLimjoco Anna Waesche Peter Vaillancourt Stratagene We introduce a set of human cDNA expression li...pFB-ERV: Retroviral Delivery of the Ecdysone Receptor Proteins
Faster, easier screening for difficult transfections when using thecomplete control kit Stratagene We describe the vector pFB-ERV, an MMLV-based replication-defectiveretroviral vector for delivery of the ecdysone receptor proteins RXR and VgEcR.In stable cell lines infected with an estima...High-Titer Retroviral Vectors for Gene Delivery
High-TiterRetroviral Vectors for Gene Delivery Stratagene The high-titer retroviral vectors pFB and pFB-Neo can be used with anyMoloney Murine L...HIV Mortality declining in India due to Generic Antiretroviral therapy drugs
Infectious Diseases Society of America (IDSA), has reported that the survival rate of patients infected with HIV has risen dramatically due to availability of affordable generic drugs in India. //India has the second highest number of patients with HIV positive next to South Africa. In India due to availability of cheap generic drugs which has reduced the cost of Anti-retroviral therapy (ART) dru...CMSI produces Low cost Anti-retroviral drugs in India
Comprehensive Medical Services India (CMSI) has produced two Anti-retrovirals which can be used in the treatment of HIV/AIDS. The two drugs Nevirapine and Zidovudine is produced by CMSI in its // manufacturing unit in Chennai, India. These two drugs were officially released by Sebastian Ouseperamppil, Director-general, Catholic Health Association. A new microbiology department which could maintai...Five AIDS Patients To Receive Experimental Anti-retroviral Drugs
A group of five AIDS victims who have been trying to gain special access to the much sought unapproved anti- HIV drugs (TMC 114 and TMC 125) can now rejoice as the Health Canada // has now issued the medication in what can be considered as a rare clinical trial. Dr. Montaner, an AIDS drugs specialist with the B.C. Centre for Excellence in HIV/AIDS at St. Paul's Hospital has been trying...Anti-retroviral drug conserving trial halted
The National Institute of Health has asked to stop SMART trial (Strategies for Management of Anti-retroviral Therapy) which is a trial on AIDS patients who are undergoing Anti-retroviral //therapy which recommends patients to have the drugs only when it is required contrasting to routine therapy which requires daily intake of these drugs. The drug-conserving trial which is aimed at re...More effective Antiretroviral HIV drug combination
Professor Joel Gallant and his team from Johns Hopkins University School of Medicine as reported in the Journal The New England Journal of Medicine // that Antiretroviral combination drug of Tenofovir, Emtricitabine and Efavirenz is found to be effective in controlling HIV load compared to most widely used drug combination Zidovudine, Lamivudine and Efavirenz. The clinical trial calle...Nelfinavir, Antiretroviral Level, HPLC
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...Saquinavir Antiretroviral Serum Level, HPLC
Description:ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' clients include more than half of the nation's university teaching hospitals and children's hospitals, maj...