While you were sleeping

... at work, much like in heart attack sufferers whose initial attack makes them more protected from subsequent attacks. "The brain could be basically resetting its bioenergetics to make itself more resistant to lack of oxygen," Professor Rae said. "It may be a compensatory mechanism to keep you alive, we just...

Passlogix Introduces Industry's Fastest Sign-On to Kiosks with New Enhancements to v-GO Session Manager

... must share account IDs; integrate v-GO with identity management systems to enable the automated provisioning of credentials to v-GO; and automate the resetting of Windows logon passwords. About Passlogix Passlogix, Inc., is the developer of the v-GO Access Accelerator Suite, the leading solution set for ...

Switch to Daylight Savings Time Will Launch First Annual Sedation Dentistry Safety Week Hosted by DOCS Education

...B) February 25, 2009 -- For nearly 10,000 specially trained dentists and their staffs, this year's switch to daylight savings time will mean more than resetting their clocks and checking their smoke alarms. These dentists will use the occasion to participate in the first annual Sedation Dentistry Safety We...

Green Valley Spa Now Offers hCG Weight Loss Therapy

...oad Dr. Simeons' complete study from the spa's Website, at no cost to them. "We opened this spa over two decades ago in concert with a program about resetting your fat thermostat," explains Green Valley's co-owner, Alan Coombs. "We're thrilled to have come full circle to a proven, safe and permanent solution...

'Food Clock' May Override Master Sleep Clock in Times of Duress

...Saper pointed out that while a time zone shift of 11 hours typically burdens our master light-dark clock with a week of difficult jetlag adjustment -- resetting just in time for the trip back home -- careful manipulation of a food clock could potentially render the shift painless and immediate. "The punch l...

Online 'Epidemic' Gives Clues to Bird Flu Spread

... contagious nature of the disease; the inability to seal off a section of the game world effectively; and player resistance to quarantine measures. resetting the game proved to be only way to halt the epidemic. Computer programs specifically designed to model infectious disease outbreaks are an important...

Targeting the Adrenal Gland Could Be Key Against Heart Failure

...tors working again and also found that the beta adrenergic receptors on the heart worked better as well. “We’ve shown that in the adrenal gland, resetting the alpha adrenergic receptors by inhibiting GRK2 causes more normal regulation and the proper feedback control, and catecholamines are lowered,” expl...

Biomarkers Found Harmful For Human Lupus

...patients have activated B cells that cause antibody production and kidney disease, but we don't know why,' he said. But he is continuing to pursue resetting part of the epigenetic code as a way to improve lupus treatment. 'We demonstrated that the response to bacterial and viral byproducts induce B-cel...

resetting in Medical Technology

Clinical Trial Results on the Sleep-Promoting Effects of Vanda Pharmaceuticals' Circadian Regulator Tasimelteon (VEC-162) Published in The Lancet

...." Results are reported from two clinical trials that demonstrate the sleep-promoting effects of tasimelteon, a novel circadian regulator that acts by resetting the body clock. The internal body clock is a complex molecular machinery that governs the rhythm of many body functions, the most well described of w...

Semafore's PI3 Kinase Inhibitor SF1126 is a Vascular Targeted Conjugate in Phase I Clinical Trials in Solid Tumors and Multiple Myeloma

...py agents is thought to be the activation of the PI3K/PTEN pathway. As a result, it is thought that inhibiting this pathway via SF1126 could cause the resetting of sensitivity to approved agents and exhibit synergistic anticancer effects. About Semafore Semafore is a clinical stage drug discovery and devel...

Semafore's SF1126 Exhibits Antitumor and Antiangiogenic Activity

... agents is thought to be the activation of the PI3K/PTEN pathway. As a result, it is thought that inhibiting this pathway, via SF1126, could cause the resetting of sensitivity to approved agents and exhibit synergistic anticancer effects. SF1126 is currently in multiple phase I trials in cancer patients. Abo...

Semafore's PI3 Kinase Inhibitor SF1126 is Active Against Tumor and Tumor Cells and Synergizes with Standard Chemotherapy Agents

... agents is thought to be the activation of the PI3K/PTEN pathway. As a result, it is thought that inhibiting this pathway, via SF1126, could cause the resetting of sensitivity to approved agents and exhibit synergistic anticancer effects. About Semafore Semafore is a clinical stage drug discovery and develop...

resetting in Biological News

Leading cause of death in 'preemies' might be controlled by resetting a molecular switch

Washington, D.C. -- Blocking signals from a key molecular receptor that normally switches on the intestines immune response but instead becomes too intense in the presence of stress and toxins may help reverse necrotizing enterocolitis (NEC), a leading cause of death in premature newborns, accor...

Travelers can avoid jet lag by resetting their body clocks

A simple, at-home treatment -- a single light box and the over-the-counter drug melatonin -- allows travelers to avoid jet lag by resetting their circadian body clock before crossing several time zones, according to new research being published in The Endocrine Society's Journal of Clinical Endocri...

A resetting signal keeps circadian rhythm on track in Drosophila fruit flies

A Brandeis University study published this week in Nature shows for the first time that a molecular signal maintains coherence among brain clock cells that regulate daily activity of Drosophila melanogaster (fruit flies). The two key groups of neurons control morning and evening activity and are ma...

How your body clock avoids hitting the snooze button

...al and Chemical Sciences study the circadian clocks of Drosophila, a type of fruit fly. Writing in the journal Current Biology , they report that the resetting process is governed by three factors, called Cryptochrome, Jetlag and Timeless. The team's findings suggest that the light responses of circadian c...

Gene that makes people 'early to bed and early to rise' demystified

...n studies of mice carrying the human FASPS gene, the researchers found that the mutant version of the Period 2 (Per2) clock gene--which is crucial for resetting the body's central clock in response to light--cannot be chemically modified by another enzyme that controls it. That failure leads to a reduction in ...

Novel connection found between biological clock and cancer

...pathway that begins when DNA is damaged and results in a temporary stoppage of cell division until the damage is fixed. The researchers found that the resetting effect of DNA damage requires the period-4 clock protein, and that period-4 is the homolog, the Neurospora version, of the mammalian checkpoint kinase...

The circadian clock: Understanding nature's timepiece

...them so they remain alert, working optimally and making the right decisions." Antle also hopes to experiment further with a technique that involves resetting the circadian clock by altering serotonin levels, the same neurotransmitter that the anti-depressant Prozac targets. He says it could one day be possi...

After a time-shift, mixed signals from the circadian clock

...roup of cells, exhibited oscillations in activity that corresponded to slow resetting of the clock in response to the shifted light schedule, while another part ...f cells, exhibited a distinct pattern of activity that corresponded to fast resetting of the clock. Perhaps contributing to the different behavior of the two ...

resetting in Biological Technology

New Study Reports Improved Patient Outcomes for Breast Cancer Patients

... follow-up data that shows a local recurrence rate of 2 percent as compared to the national norm of 4-9 percent. "This study basically suggests a resetting of the bar on how to do lumpectomies and what patients can expect if it is done this way," said Henry Mayo's Breast Center Medical Director Gregory Se...

ev3 Inc. Reports 2008 First Quarter Financial Results and Revised 2008 Guidance

...ation of our endovascular procedures. I believe these initiatives will in turn drive growth and shareholder value." Palmisano commented further, "In resetting our guidance, we took into account the factors that could affect our business in 2008, including the performance of our U.S. atherectomy business, whi...

Semafore to Present at BIO CEO & Investor Conference

... agents is thought to be the activation of the PI3K/PTEN pathway. As a result, it is thought that inhibiting this pathway, via SF1126, could cause the resetting of sensitivity to approved agents and exhibit synergistic anticancer effects. About Semafore Semafore is a clinical stage drug discovery and devel...

Can we prevent Web 2.0 from being a bubble?

...et of individuals has significantly raised the barrier to staying power. Businesses will be proved and disproved in the market, constantly setting and resetting business value, making over inflation more difficult. This, we can hope, will invigorate entrepreneurs to start companies that test new ideas in th...

Simultaneous Determination of Residues of Approximately 100 Pesticides and Metabolites in Fruit and Vegetables by LC/MS/MS

...ometric detection. As shown in Figure 4 (and in the demo files given on the CD), such periods are unnecessary here, avoiding the resetting of switching times with new columns, other pumps etc. An example of a real sample with incurred residues is given in Figure 5, which shows ...