Compounds that trigger beta cell replication identified by JDRF funded researchers
February 25, 2009, New York, NY Researchers at the Genomics Institute of the Novartis Research Foundation (GNF) have identified a set of compounds that can trigger the proliferation of insulin-producing cells in the pancreas, using sophisticated high-throughput screening techniques.
Health and Pension Benefits Provider Turns to Xiotech's TimeScale Replication Services to Protect Critical Data
Hosted Service Provides Cost-Effective, Highly Available and Secure Data
for United Mine Workers of America Health and Retirement Funds
EDEN PRAIRIE, Minn., Sept. 25 /PRNewswire/ -- Xiotech Corporation today
announced that the United Mine Workers of America (UMWA) Health and
Children's Hospital Boston Deploys AutoVirt Solution to Increase Speed and Efficiency of Windows Data Replication
AutoClone Software Reduces Data Migration Window from 12 Days to 27 Hours
Nashua, N.H., May 19 /PRNewswire/ -- AutoVirt(TM), Inc., the leading provider of Windows file server virtualization solutions, today announced that Children's Hospital Boston, an internationally renowned center for med...
Burnham researchers illuminate mechanisms that regulate DNA damage control and replication
LA JOLLA, Calif., January 5, 2008Scientists at Burnham Institute for Medical Research (Burnham) have demonstrated important new roles for the protein kinase complex Cdc7/Dbf4 or Cdc7/Drf1 (Ddk) in monitoring damage control during DNA replication
and reinitiating replication
following DNA repair. S...
New Compound Slows HIV Replication
It could mean development of new class of drugs, researchers say
WEDNESDAY, May 28 (HealthDay News) -- A new compound that inhibits HIV protease has been developed by researchers at the University of Michigan.
The protease, which is necessary for HIV replication, is a common targe...
New agent strikes at respiratory syncytial virus replication
GALVESTON, Texas University of Texas Medical Branch at Galveston researchers have achieved promising results with a potential new weapon against respiratory syncytial virus, the most common cause of infant hospitalization in the United States.
In an effort to find an effective antiviral therap...
Replication in Medical Technology
IDX899 Demonstrates Rapid and Profound Inhibition of HIV Replication in a Phase I/II Clinical Trial in Treatment-Naive HIV-Infected Patients
CAMBRIDGE, Mass., Feb. 6 /PRNewswire-FirstCall/ -- Idenix
Pharmaceuticals, Inc. (Nasdaq: IDIX ), a biopharmaceutical company engaged
in the discovery and development of drugs for the treatment of human viral
and other infectious diseases, today reported data for IDX899, a
NIEHS Researchers Identify Enzyme Critical in DNA Replication
BETHESDA, Md., July 5, 2007--In this weeks issue of Science,
researchers from the National Institute of Environmental Health
Sciences (NIEHS) and Umeö University in Sweden report an
important discovery about a critical new role that an enzyme called
DNA polymerase epsilon plays in replicating...
Schering-Plough Expands Vicriviroc Phase II Study in Treatment-Naive Patients With HIV
...nded to stage two, in which the enrollment target is an additional 105 patients.
Unlike other classes of HIV drugs that work to inhibit viral replication
within human CD4+ cells, most of which are part of the immune system, vicriviroc is an HIV entry inhibitor designed to prevent the virus from infectin...
Gene Findings Unlocking Reasons for Neuroblastoma Risk
...of Medicine. Scientists from six other centers in addition to Children's Hospital and the University of Pennsylvania contributed to the discovery or replication
of the findings.
Capasso et al, "Common variations in BARD1 influence susceptibility to high-risk neuroblastoma," Nature Genetics , published...
Jennerex Therapeutic Research Collaboration With Ottawa Hospital Research Institute Selected for $10 Million Grant From Ontario Institute for Cancer Research
... cancers. Jennerex's products target, attack and eradicate cancers through a novel and potent oncolytic mechanism that is dependent on highly-specific replication
of the company's poxviruses in cancer cells. These products simultaneously stimulate the body's immune response to the cancer. Of note, this mechanism...
FDA Advisory Committee Votes in Favor of Zyprexa for Two Adolescent Indications
... Kessler RC, Chiu WT, Demler O, Walters EE. Prevalence, severity, and comorbidity of twelve-month DSM-IV disorders in the National Comorbidity Survey replication
(NCS-R). Archives of General Psychiatry, 2005 Jun;62(6):617-27.
(8) Mauricio Tohen et al. (2007). Olanzapine versus Placebo in the Treatment of ...
Replication in Medical Products
Description:... Superior imaging through a 410,000 pixel CCD, unseen color replication
from a digital signal processor in the scope, and the added benefit of four way tip deflection make the TF410 a superior choice for laparoscopy....
Description:...C is a revolutionary advancement in spine surgery, providing surgeons unprecedented ability to assess and manage their patients. The eDISC's unmatched replication
of human disc motion separates the eDISC from 1st and 2nd generation designs.
Created to withstand the motions and loads of the lumbar spine, th...
Description:... a working depth of 1.5cm, the MultiBlot tray is ideal for:
Plating solid media and for blot hybridization and processing.
Performing colony replication
of bacterial or yeast libraries on membranes overlayed on solid media in the tray.
Plating bacteria and yeast and performing colony and plaque li...
Company:Matrix Technologies Corporation
Description:...ably and quickly diagnose all strains of influenza A and B. The test uses a unique substrate for influenza neuraminidase, an enzyme that assists viral replication
by promoting the release of the virus from infected cells. The ZstatFlu substrate is labeled with a chromagen. When influenza virus is present, the vi...
BioPro Total Knee System
Description:...and are equally proportioned and contoured to be in compliance with the articular outline and dimensions of the normal knee. Each individual size is a replication
of the normal topographic anatomy of the knee and of each other....
Cervive™ Anterior Cervical Plating System
Description:... Cervive is an Anterior Cervical Plating System that has been engineered to provide flexibility and simplicity for the spinal surgeon, allowing replication
of normal anatomical function and safe fixation of the plate. Cervive includes numerous features that meet the needs of the spinal surgeon in providin...
Company:Corin Group PLC
Replication in Medical Dictionary
...keting objectives through self-replicating viral processes, analogous to the spread of... Article detailing the etymology, origins, anatomy, and replication
of ... Negative-sense viral RNA is complementary to mRNA and thus must be converted to ... virus n. , pl. -ruses . Any of various simple submi...
...rap , Down-The-Line, and Nordic Trap . American Trap is most popular in the United... The Rat-L-Trap has Liv-N-Sound which produces a life-like replication
of distressed baitfish that predator fish just can't resist. ... I was using SY2 Pro Trap ! ... Trap - Definition of Trap at Dictionary.com a...
...a retrovirus that is native to. rodents. ... Retroviruses contain viral RNA and several copies of reverse transcriptase (DNA polymerase) ... replication
of the retrovirus , HIV (human immunodeficiency ... Britannica online encyclopedia article on retrovirus (virus group), any of a group of virus...
...iosynthesis to the... Folic acid is a B vitamin needed for cell replication
and growth. ... Women who take folic acid -containing multivitamin suppl...es of folic acid . Folic acid is a B vitamin needed for cell replication
and growth. ... Women who take folic acid –containing multivitamin suppl...
Acute HIV infection
... Acute HIV infection is a period of rapid viral replication
that immediately ... Acute Human Immunodeficiency Virus type 1 infection ". N. Engl. J. Med. ... Acute HIV infection is caused...
Replication in Biological News
Visualizing virus replication in three dimensions
Dengue fever is the most common infectious disease transmitted by mosquitoes some 100 million people around the world are infected. Researchers at the Hygiene Institute at Heidelberg University Hospital were the first to present a three-dimensional model of the location in the human cell where th...
Answer to troublesome question of why some genetic assoc. studies have failed replication attempts
Boston, MA - A team of researchers from Harvard School of Public Health (HSPH), Brigham and Women's Hospital (BWH), and elsewhere have described a possible reason why some studies have been unable to replicate associations between genes and traits -- namely that the strength of a gene/trait associ...
Copy number variation may stem from replication misstep
Genome rearrangements, resulting in variations in the numbers of copies of genes, occur when the cellular process that copies DNA during cell division stalls and then switches to a different genetic template, said researchers at Baylor College of Medicine in Houston in a report that appears today ...
DNA replication behavior in complex organisms may foreshadow leaps in genomic discoveries
For the first time, findings by scientists at the Genome Institute of Singapore (GIS) may be paving the way for more efficient analyses and tests related to the replication
of cells, and ultimately, to the better understanding of human biology, such as in stem cell research.
Features of replication suggest viruses have common themes, vulnerabilities
MADISON - A study of the reproductive apparatus of a model virus is bolstering the idea that broad classes of viruses - including those that cause important human diseases such as AIDS, SARS and hepatitis C - have features in common that could eventually make them vulnerable to broad-spectrum anti...
JDRF-funded researchers discover proteins regulating human beta cell replication
NEW YORK, January 16, 2009 - Researchers at the University of Pittsburgh School of Medicine, funded by JDRF, have discovered that adult beta cells have the ability to replicate with the help of a protein known as cdk6. This research was led by Andrew F. Stewart, M.D., a Professor of Medicine and ...
Replication in Biological Technology
CellCyte Genetics Corp. Forms Device Division to Develop and Manufacture Stem Cell Cultivation and Replication Products
KIRKLAND, Wash., Sept. 19 /PRNewswire-FirstCall/ -- CellCyte Genetics
Corporation (the "Company") (OTC Bulletin Board: CCYG) has formed a new
Device Division in order to develop, manufacture and market its patented
line of stem cell cultivation and replication
devices. CellCyte Genetics is de...
Whole Gel Eluter Purification of a Functional Multiprotein DNA Replication Complex, Rev A
HaiYan Jiang a,e , Robert J. Hickey a-e, h , Pamela E. Bechtel f , Philip
W. Wills a, e , SuHua Han a,e , Timothy D. Tom a-g , YueTong Wei a,e , and Linda
H. Malkas a-e,+ , (a) Department of Pharmacology and Experimental Therapeutics
(b) Program in M...
Your Data: Silencing Hepatitis C Virus Replication With In Vitro Transcribed siRNAs
The Silencer siRNA
Construction Kit uses an in vitro transcription reaction and
column purification to prepare transfection-ready siRNAs. With
this kit, multiple siRNAs can be prepared in ~24 hours. Below
Novavax Announces Selection of a Respiratory Syncytial Virus Vaccine Candidate for Advanced Preclinical Studies
... vaccine candidate in mice showed that it induced production of antibodies that neutralized live RSV. In addition, the vaccine protected mice against replication
of RSV in the lungs. The study included groups of mice that received two injections of RSV-F vaccine at doses of 1, 10, or 30 micrograms with and wit...
Santaris Pharma - Interim Report for the Period 1 January to 30 June 2009
SPC3649 is a potent and specific inhibitor of microRNA-122 known to be
involved in cholesterol metabolism and in hepatitis virus replication
liver. In April 2009, Santaris Pharma completed a Phase I First-in-Man single
dose study of SPC3649 with 60 healthy volunteers and the Company ...
Cynvec to Present at The 2009 New York Venture Summit
...t, CYN 101, to be used as a single agent or in combination with cytotoxics, monoclonal antibodies, chemotherapeutic agents and radiation. CYN 101 is a replication
defective, apoptotic RNA vector that has shown tumor eradication and highly significant survival rates in pre-clinical models of ovarian and pancreati...
Replication in Biological Products
SV40 Large T Antigen from Chimerx
Description:... SV40 Large T antigen initiates replication
from the SV40 origin of replication
in the presence of the host proteins. This product can be used in conjunction with our SV40 DNA replication
Kit cat. no. 8050. For bulk purchases contact llo...
Rabbit Anti-Human GMNN Polyclonal Antibody, Unconjugated from Proteintech Group, Inc.
Description:... geminin, DNA replication
Company:Proteintech Group, Inc.
Molecular Virology from Promega
Description:...ts include: information on positive strand plant viruses, paramyxoviruses, influenza and immunodeficiency viruses. It also covers analysis of viral NA replication
and the construction of vectors from various sources....
Staccato Automated Systems from Caliper Life Sciences
Description:...loss of initial investment. The Staccato Sciclone replication
Station is a highly modular system for automating complex reformatting, replication
and hitpicking operations. The most basic Sciclone replication
Station features a Sciclone ALH 3000 liquid handle...
Company:Caliper Life Sciences
Freedom EVO 150 from Tecan
Description:...t Hit picking and plate reformatting Cell culture and cell maintenance Sample preparation for flow cytometry Compound characterization Plate replication
Compound stability Automated assays for Absorption, Distribution, Metabolism, Excretion, Toxicity (ADMET) include: Micosome and hepatocyte met...
TC-512 Thermal Cycler from Barloworld Scientific Ltd
Description:...fering security and flexibility. Gradient calculator: The gradient calculator function displays the temperature of each column of tubes. This ensures replication
of the experimental conditions. 4-Fold control: Each block consists of 8 Peltier units, controlled by 4 independent temperatures thermistor (control ...
Company:Barloworld Scientific Ltd
Replication in Biological Definition
In biology , replication
is the act or ability to make a copy. (Mostly commonly meaning molecular replication).
Self-replication is the act of a molecule (or any other pattern) making a copy of itself.
is the act of copying the genetic material of a cell ( DN...
...integrate itself into the bacterial chromosome by genetic recombination ) of about 100 kb (kilo base pairs ) length. It carries its own origin of replication
, called oriV . There can only be one copy of the F-plasmid in a bacterium (which is then called F-positive ), either free or integrated.
.... The first part of cell reproduction involves the replication
of the parental cell's DNA . The second major iss...
For details see the individual articles on DNA replication
, binary fission , mitosis , meiosis , and cyt...rt of the cell reproduction process. Prior to DNA replication
, the DNA content of a cell can be represented as ...
... be accessed for transcription , regulation, and replication
. Chromosomes were first observed by Karl Wilhelm...s are special structures called telomeres . DNA replication
begins at many different locations on the chromoso...taken into account. Bacterial chromosomes initiate replication
and one origin of replication.
... DNA replication
Deoxyribonucleic acid ( DNA ) is a nucleic ...ructure
4 The role of the sequence
5 DNA replication
6 Mechanical properties relevant to biology ...sequence itself is the description for genes;
is performed by splitting (unzipping) the double ...
...l and does not use an RNA intermediate during replication. Viruses that either have RNA as their genetic material or use an RNA intermediate during replication
are called RNA viruses . The DNA can either be single- (ssDNA) or double-stranded (dsDNA), the latter being more common.
Single-stranded DNA is usu...
Replication in Biological Dictionary
, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA. This process is "semiconservative" in that each strand of the original double-stranded DNA molecule serves as template for the... Replication
Origin of replication
The origin of replication
is a particular sequence in a genome at which replication
is initiated. This can either be DNA replication
in living organisms such as prokaryotes and eukaryotes, or RNA replication
in RNA viruses, such as double-stranded RNA viruses. DNA... DNA replica...
, the basis for biological inheritance, is a fundamental process occurring in all living organisms to copy their DNA . This process is "semiconservative" in that each strand of the original double-stranded DNA molecule serves as template for the... In a cell, ...
Triplet repeat expansion
... of DNA Instability in Triplet Repeat Expansion During in vitro DNA replication
... DNA instability appeared to induce triplet repeat expansion in vitro. ... Abasic Sites Induce Triplet - repeat Expansion during DNA replication
in Vitro ... The occurrence of triplet - repeat expansion (TRE)1 during...
... is often used to describe virus-mediated DNA... transfection n. Infection of a cell with purified viral nucleic acid, resulting in subsequent replication
of the virus in the cell Genlantis is focused on developing innovative reagents for transfection , gene expression, Gene Silencing,RNA interf...
... coat protein of a differing virus. ... transcapsidation ( ¦tranz′kapsə′dāshən ) ( virology ) Change in the capsid of PARA (particle aiding replication
of adenovirus) from one type of capsid n. The protein shell that surrounds a virus particle. [From ... transcapsidation (virology) herpesv...