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Repair at Biology News

Deficient DNA Repair Capacity Associated With Increased Risk Of Breast Cancer

Deficiencies in the ability of cells to repair damaged DNA are associated with an increased risk of breast cancer, according to a new study in the January 19 issue of the Journal of the National Cancer Institute. is the system of defenses designed to protect the integrity of the genome. Studies have suggested that deficiency...

DNA Recombination and Repair—A New Twist to RecA Function

Molecular motors harness the energy of ATP (or GTP, a related energy currency) and transform it into mechanical force. Well-known examples of motors include myosin and dynein, proteins that use ATP to ferry intracellular cargo along fibers made of actin or tubulin proteins. The ATP-dependent assembly of actin or tubulin fibers itself can work as a motor: for instance, the march of white blood cel...

Heart repair gets new muscle

Some organs in the human body deal with injury better than others. A flesh wound or muscle tear might hurt, but, assuming you are otherwise healthy, both will heal. The prognosis for a heart attack, on the other hand, is not so clear-cut. It has long been thought that cardiac cells (cardiomyocytes) lack the capacity for self-renewal and repair, impeding the chances of a full recovery from...

Nano-bumps could help repair clogged blood vessels

Biomedical engineers at Purdue University have shown that "vascular stents" used to repair arteries might perform better if their surfaces contained "nano-bumps" that mimic tiny features found in living tissues. The researchers already have shown in a series of experiments that bone and cartilage cells in petri dishes attach better to materials that possess smaller surface bumps than are f...

New understanding of DNA repair may pave way to cancer treatments

A Burnham Institute study has found that a protein known for its role in gene regulation has another important function, that of initiating DNA repair. The study, published in the May 27th edition of Molecular Cell, points to new targets for treatment of cancer. Ze'ev Ronai, Ph.D., Director of the Institute's Signal Transduction Program, and his colleagues found that the protein ATF2 ("Ac...

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Repair at Biology Products

DNA Repair Sampler Kit from BD Biosciences Pharmingen

Description:DNA Repair Sampler Kit 10g each...
Company:BD Biosciences Pharmingen
Repair at Biology Technology

RT-PCR Primer Sets for Human and Mouse Mismatch Repair Genes

Stratagene Cloning Systems from the cDNAsequences of mismatch repair genes. These genes code for specialized proteinsthat participate in correcting areas of base mispairing in DNA. We have...

DNA Damage and Repair - Quantification of Sub-Cellular Events Using Automated Confocal Imaging

Oxidative stress, radiation and other external insults have been shown to damage DNA molecules in cells derived from organisms as diverse as bacteria, yeast, drosophila, rodents and man (Friedberg et al. 2005). The presence of DNA damage may lead to cell cycle checkpoint arrest to allow time for DNA repair...
Repair at Biology Dictionary

Mismatch repair

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DNA repair

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Repair at Medicine News

Clotting Protein plays a role in nerve repair

According to a new study, fibrin, a protein that helps form blood clots, may also be involved in regulating the repair of nerve damage. The discovery could lead to new strategies for repairing diseases of the nervous system, such as multiple sclerosis, although the research is still on the basic science level.// In multiple sclerosis, the slow destruction of myelin--the thin, protecti...

Heart may pull Cells from Body to Self-repair

According to researchers, after analysis of cells in men with transplanted hearts from female donors, the proof is the piling up that the heart may be able toregenerate itself at least somewhat by recruiting cells from elsewhere in the body.// Traditionally, it was thought that once cells were damaged or dead, they could not be replaced or repaired by the heart. By looking at the Y chr...

Bone marrow stem cells may help repair cardiac tissues

Two new studies, though small, have boosted confidence in a method used to repair cardiac tissues damaged by a heart attack. Researchers have found that stem cells derived from bone marrow which is much less controversial than embryo cells// helps patients who have had a heart attack and had undergone conventional bypass therapy. Doctors in eastern Germany found that when patients who...

Bones repair themselves with bone marrow cells

A research project carried out by Juliette van den Dolder at the University of Nijmegen has shown that new bone cells can be grown into bone fractures with the help of specially prepared titanium mesh and bone marrow cells. Researchers inserted a titanium mesh scaffold into a bone fracture in a rat. They allowed bone marrow cells to grow on this. This resulted in new bone growth being sti...

Melanoma caused by low DNA repair capacity

Melanoma is the deadliest form of skin cancer and it has been shown through previous research studies that the risk is increased by exposure to sunlight, whose UV rays cause damage to DNA that triggers cancer. However, it has not been clear why some people are more prone than others to melanoma. Researchers have now found out through a study involving a group of 312 people with melanoma t...

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Repair at Medicine Products

Meniscal Repair/Suture Instruments

Description:For universal arthroscopic meniscal repair/suture. Uses double-armed, single-throw sutures....
Company:Innomed, Inc.

Zone Specific® II Meniscal Repair System

Description:A complete system of cannulas, needles and rasps specifically designed for inside-out meniscal repair procedures....
Company:Linvatec Corporation (now ConMed)

RapidLoc Meniscal Repair System

Description:The RapidLoc Meniscal Repair System is a second-generation "all-inside" system that offers several advantages over current systems including "inside-out" suture repair techniques and current "all-inside" rigid implants. This system is quick, simple, reproducible, reliable, and flexible in many ways, all while decreasing iatrogenic morbidity....
Company:DePuy Mitek

Super Revo® Rotator Cuff Repair System

Description:The Linvatec 5mm Super Revo Suture Anchor offers a simple and reproducible technique for arthroscopic or a mini-open rotator cuff repair. The cutting tip requires no pre-drilling and the anchor is pre-threaded with two #2 strands of braided polyester suture. The potential pitfalls of suture management are avoided with the Independent Suture Sliding (I.S.S.™) Eyelet design. The sutures slide...
Company:Linvatec Corporation (now ConMed)

Revo® Rotator Cuff Repair System

Description:The 4mm diameter Revo suture anchor is designed primarily for arthroscopic and open rotator cuff repair. Additional applications include other shoulder repair procedures, as well as use in knees and small joints....
Company:Linvatec Corporation (now ConMed)

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Repair at Medicine Technology

AGI Dermatics Data Shows the 8 Oxo-Guanine Repair Enzyme OGG1 Encapsulated in Liposomes, Reduces MMP-1 and TNF-alpha in UV Irradiated Skin Cells

Clinical Data Presented at the Society for InvestigativeDermatology FREEPORT, N.Y., May 16, 2007 /PRNewswire-FirstCall/ -- AGIDermatics today announced new clinical research that the8-oxo-guanine DNA glycosylase (OGG1) encapsulated in liposomesenhances DNA repair and reduces MMP-1 and TNF-alpha in UVirradiated skin cells. The data was presented at the 68th AnnualMeeting of the Society fo...

Sangamo BioSciences Announces Presentation of ZFP Therapeutic Data From Nerve Regeneration Program at American Society for Neural Therapy and Repair Meeting

Statistically Significant Improvements in Function in Spinal CordInjury Model With ZFP TF Treatment RICHMOND, Calif., May 03, 2007 /PRNewswire-FirstCall/ -- SangamoBioSciences, Inc. announced today the presentation of preclinicaldata from its ZFP Therapeutic(TM) program in nerve regeneration atthe Fourteenth Annual Conference of the American Society for NeuralTherapy and Repair. The data...

Data Show SuperGen's Multi-Targeted Tyrosine Kinase Inhibitor Suppresses Critical Double-Stranded DNA Repair Protein, Rad51

Other Presentations at AACR Highlight Progress in SuperGen'sOncology-Focused Pre-Clinical Pipeline LOS ANGELES, April 19, 2007 /PRNewswire-FirstCall/ -- SuperGenInc. today announced that MP470, its multi-targeted tyrosine kinaseinhibitor, suppresses the Rad51 protein, a critical component ofdouble- stranded DNA repair in cancer cells as part of a series ofpresentations at the 2007 America...
Repair at Medicine Dictionary

Tendon repair

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Pectus excavatum repair

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Hernia repair

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Bone fracture repair

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Breaking Biology News(10 mins):MIT creates new material for fuel cells 2MIT creates new material for fuel cells 3Plant biologists discover unexpected proteins affecting small RNAs 2Plant biologists discover unexpected proteins affecting small RNAs 3Stowers Institute researchers identify gene linked to vertebral defects in patient populations 2Does fishing on drifting fish aggregation devices endanger the survival of tropical tuna? 2Does fishing on drifting fish aggregation devices endanger the survival of tropical tuna? 3Floating a big idea 3A MIT demos ancient use of rafts to transport goods 2548 1Floating a big idea 3A MIT demos ancient use of rafts to transport goods 2548 2Floating a big idea 3A MIT demos ancient use of rafts to transport goods 2548 3Floating a big idea 3A MIT demos ancient use of rafts to transport goods 2548 4Molecular biology of sleep apnea could lead to new treatments 14716 1Molecular biology of sleep apnea could lead to new treatments 14716 2eMPR Digital Drug Reference Reaches 50 000 Downloads and the Publisher Launches a Raffle for Healthcare Providers 14711 1eMPR Digital Drug Reference Reaches 50 000 Downloads and the Publisher Launches a Raffle for Healthcare Providers 14711 2eMPR Digital Drug Reference Reaches 50 000 Downloads and the Publisher Launches a Raffle for Healthcare Providers 14711 3White Paper Advises Pharma Manufacturers on How to Select an Aseptic Fill Finish Contractor Avoid the Most Common Mistakes 4080 1White Paper Advises Pharma Manufacturers on How to Select an Aseptic Fill Finish Contractor Avoid the Most Common Mistakes 4080 2
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