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Regulates in Medical News

Farnesoid X receptor regulates cystathionase

The expression and activity of Cystathionase is reduced in rodent models of liver injury, leading to hyper-homocysteinemia and impaired generation of hydrogen sulphide, two factors that contribute to endothelial dysfunction and increased intrahepatic resistance. In the present study the analysis...

URI scientists reveal mechanism that regulates cancer-causing gene

KINGSTON, R.I. March 26, 2009 Two University of Rhode Island scientists have revealed how a cancer causing protein is regulated by reactive oxygen species (ROS) -- a type of stress signal. Their findings provide new insight into how this protein normally behaves in human cells and may help in t...

Consumer/Health Groups Call for Meaningful Change in How Treasury Department Regulates Alcohol Labeling

WASHINGTON, Dec. 12 /PRNewswire-USNewswire/ -- Even as the Obama Administration sets its sights on stabilizing and strengthening the U.S. economy, a coalition of public interest groups today called on the transition team and incoming Treasury Secretary Timothy Geithner to move quickly on another m...

Portuguese scientists discover new mechanism that regulates formation of blood vessels

Researchers in one of the external groups of the Instituto Gulbenkian de Cincia (IGC), in Portugal, have discovered a novel mechanism which regulates the process whereby new blood vessels are formed and wounds heal, including chronic wounds, such as those found in diabetic patients and those suffe...

USC researchers identify key mechanism that regulates the development of stem cells into neurons

Los Angeles, Calif. Nov. 10, 2008Researchers at the University of Southern California (USC) have identified a novel mechanism in the regulation and differentiation of neural stem cells. Researchers found that the protein receptor Ryk has a key role in the differentiation of neural stem cells, ...

UCLA and biotech company develop first blood test to measure key hormone that regulates iron

FINDINGS: UCLA and Intrinsic LifeSciences, a San Diego biotech company, developed the first method to measure the hormone, hepcidin, which regulates the absorption of dietary iron and its distribution in the body. This new blood test will help clinicians manage chronic conditions affecting mill...
Regulates in Medical Technology

Radius' Investigational Bone Anabolic Agent, BA058, Increased Bone Mineral Density (BMD) at Key Fracture Sites in Phase 2 Clinical Trial in Postmenopausal Osteoporosis

...tor, PTHrP and its analogs play a distinct biological role from the PTH (parathyroid hormone) peptide by activating different signaling responses--PTH regulates calcium homeostasis and bone resorption by acting primarily on target cells in bone and kidney, whereas PTHrP and its analogs regulate cell proliferat...

Bionovo's Estrogen Receptor Beta Selective Drugs Have Unique Gene Expression and Cell Type Specificity

...tivity and pattern of gene expression of the three classes of ERb selective compounds compared to the natural hormone estradiol, which non-selectively regulates both ERa and ERb . The most significant finding in the study was that the ERb-selective compounds regulate a number of genes differently than estradio...

Studies Show AFRESA(R) Controls Post-Meal Sugar Levels With Less Weight Gain and Hypoglycemia Risk for Diabetes Patients

...racterized by the body's inability to properly regulate levels of blood glucose, or blood sugar. Insulin, a hormone produced by the pancreas, normally regulates the body's glucose levels, but in people with diabetes insufficient levels of insulin are produced (type 1 diabetes) or the body fails to respond adeq...

AFRESA(R) Phase 3 Pulmonary Function Safety Data in Patients with Diabetes Presented at ADA

...racterized by the body's inability to properly regulate levels of blood glucose, or blood sugar. Insulin, a hormone produced by the pancreas, normally regulates the body's glucose levels, but in people with diabetes insufficient levels of insulin are produced (type 1 diabetes) or the body fails to respond adeq...

PROTECT-1 Phase II/III Induction-Stage Results for ChemoCentryx's Traficet-EN(TM) Presented in Oral Session at DDW 2009 Conference

...es, inflammatory disorders and cancer. The chemokine system is a network of secreted chemokine molecules, or ligands, and cell surface receptors that regulates inflammation. Based on its proprietary drug discovery and drug development platform, ChemoCentryx has internally generated multiple clinical and precl...

Celladon Provides MYDICAR(R) Program Update of First-In-Human Trial for Advanced Heart Failure at American Society of Gene Therapy Annual Meeting

...ecular therapies for the treatment of heart failure. The company's products target the key enzyme deficiency in advanced heart failure, SERCA2a, which regulates calcium cycling and contractility in heart muscle cells. Celladon's first product candidate, MYDICAR, delivers the gene for the SERCA2a enzyme. MYDICA...
Regulates in Medical Products

SHBG IRMA Test

Description:...hydrotestosterone (combined 95% bound to SHBG) and, to a much lesser extent, estradiol [1]. SHBG specifically binds C18 and C19 steroid structures and regulates the bioavailability of sex steroids. SHBG is produced primarily in the liver. SHBG synthesis and release are regulated by a number of factors which le...
Company:Diagnostic Systems Laboratories, Inc.

Renin IRMA Test

Description:... Renin, a protease secreted by the kidney, plays a vital role in the renin-angiotensin system. The renin-angiotensin system regulates blood pressure, and controls water and electrolyte retention by the kidney. Renin is secreted in response to several factors including decreased intra...
Company:Diagnostic Systems Laboratories, Inc.

Tummy Tuck Panty

Features:... Insant tummy support Designed as a stage 2 post-surgical compression panty Breathable cotton-lined Spandex/Nylon blend Front adjusting waist band regulates compression Rear band supports lumbar area, eases lower back pain Full-seam back panel provides additional support ...
Company:ClearPoint Medical

3M™ DuraPrep™ Surgical Solution

Features:...water-insoluble film that resists washing away by blood and saline optimizing the persistent effects of iodine Self-contained, unit-dose applicator regulates flow of solution to minimize drips and ensures an even application of prep Maintains low bacterial counts under transparent dressings for up to thre...
Company:3M Worldwide

PneumaticWalker™ Diabetic System

Features:... An aircell lined shell that maximizes plantar unloading, regulates shear stress, and provides protection and immobilization Graduated compression to help reduce edema Multi-aircell support for a "total contact" fi...
Company:Aircast

Novacor LVAS

Features:...des the pumping chamber and electromechanical driver, encased within a biocompatible shell. Controller: The microprocessor-based Controller regulates the flow of power to the implanted pump/drive unit, controlling the pumping action of the device. It monitors system function, alarming for out-of-ran...
Company:World Heart Corporation
Regulates in Medical Definition

Autoimmune regulator

... Projection of an Immunological Self-Shadow Within the Thymus by the Aire Protein. Science 298 (5597), 1395-1401 ^ Liston, A. et al. (2003) Aire regulates negative selection of organ-specific T cells. Nat Immunol 4 (4), 350-354 External links MeSH AIRE+protein ...

Thymocyte

... Projection of an Immunological Self-Shadow Within the Thymus by the Aire Protein. Science 298 (5597), 1395-1401 ^ Liston, A. et al. (2003) Aire regulates negative selection of organ-specific T cells. Nat Immunol 4 (4), 350-354 ...
Regulates in Medical Dictionary

Sphincter

...artificial sphincter is inserted into an area of the urinary tract or rectum, ... The lower esophageal sphincter at the top of the stomach regulates food passing ... The pyloric sphincter at the bottom of the stomach governs the passage of food ... Sphincter information including symp...

Sodium

...nt of the 3rd period and so is in Group IA. ... Sodium metal has a body centered cubic structure. ... Sodium is the primary electrolyte that regulates the extracellular fluid levels in the body. ... Sodium is essential for hydration because this mineral pumps ... 1000Bulbs.com offers high press...

Sleep Disturbance

...lead to poor performance, health, and moods. Shop for vitamins, supplements & natural health products - Melatonin is a natural hormone that regulates sleep . Travelers and workers on rotating or late shifts can... The National Fragile X Foundation unites the fragile X community to enrich lives ...

Renin

...lar volume, and arterial vasoconstriction. Thus it regulates the body's mean arterial blood pressure. ...dosterone system (RAAS) is a hormone system that regulates blood pressure and water (fluid) balance. R... is part of the renin -angiotensin system, which regulates blood pressure. ... Renin - Definition of ...

PTH

...ne analog PTH (1-34) with Novasomer A cream, ... parathyroid hormone n. ( Abbr. PTH ) A hormone produced by the parathyroid glands that regulates the amount of calcium and phosphorus in the ... PTH ) ... Complete information for PTH gene (protein-coding), parathyroid hormone ... Fun...

Potassium

...f a potassium test might mean Find information on this disorder of high potassium , its causes, incidence and risk factors. ... aldosterone regulates kidney removal of sodium and potassium . ... Potassium is a mineral involved in electrical and ... Many foods contain potassium . ... So...
Regulates in Biological News

Pitt team finds molecule that regulates heart size by using zebrafish screening model

PITTSBURGH, July 5 Using zebrafish, researchers at the University of Pittsburgh have identified and described an enzyme inhibitor that allows them to increase the number of cardiac progenitor cells and therefore influence the size of the developing heart. The findings are described in the advance...

Protein regulates movement of mitochondria in brain cells

Scientists have identified a protein in the brain that plays a key role in the function of mitochondria the part of the cell that supplies energy, supports cellular activity, and potentially wards off threats from disease. The discovery, which was reported today in the Journal of Cell Biology ,...

Heart protein regulates blood vessel maintenance

BOSTON (May 11, 2009) In a study led by Akiko Hata, PhD, of Tufts University School of Medicine, researchers have shown that a protein expressed in the heart, FHL2, inhibits the genes necessary for the quiescence of vascular smooth muscle cells (vSMCs), which line blood vessels. Vascular smooth ...

System that regulates blood pressure is amiss in some healthy, young blacks

AUGUSTA, Ga. When stress increases blood pressure, a natural mechanism designed to bring it down by excreting more salt in the urine doesn't work well in about one-third of healthy, black adolescents, researchers report. They hope the finding, which is being presented May 8 at the American Soc...

DREAM: 1 gene regulates pain, learning and memory

This release is available in German . In 2002, a group of scientists at the University of Toronto was able to identify a gene which they dubbed DREAM (downstream regulatory element antagonistic modulator). The gene's function was highly interesting: it obviously served as a key regulator ...

Protein that regulates hormones critical to women's health found in pituitary

MADISON University of Wisconsin-Madison researchers have solved the mystery surrounding a "rogue protein" that plays a role in the release of neurotransmitters and hormones in the brain. The scientists found abundant amounts of the puzzling protein whose main location and function were unkno...

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Regulates in Biological Technology

The let-7 microRNA Family Regulates RAS: Implications for Development and Oncogenesis

Research Summary Drs. Frank Slack, Steven Johnson, and Helge Grosshans, and Ms. Kristy Reinert at Yale University, in collaboration with Ambion scientists, discovered that the let-7 microRNA (miRNA) famil...

LNA-Based HIF-1 Alpha Inhibitor Shows Early Signs of Clinical Benefit

...F-1 alpha is a well-validated target in many common solid tumors. EZN-2968 is the first drug candidate to target the HIF-1 transcription factor, which regulates expression of many key genes important in cancer biology, including genes that regulate angiogenesis, cell metabolism, cell proliferation, cell death ...

ChemoCentryx's Traficet-EN(TM) Phase II/III Induction Phase Data in Crohn's Disease to be Featured in Oral Presentation at 2009 Digestive Disease Week

...es, inflammatory disorders and cancer. The chemokine system is a network of secreted chemokine molecules, or ligands, and cell surface receptors that regulates inflammation. Based on its proprietary drug discovery and drug development platform, ChemoCentryx has internally generated multiple clinical and precl...

ChemoCentryx Identifies Novel Small Molecule C5aR Antagonist

...es, inflammatory disorders and cancer. The chemokine system is a network of secreted chemokine molecules, or ligands, and cell surface receptors that regulates inflammation. Based on its proprietary drug discovery and drug development platform, ChemoCentryx has internally generated multiple clinical and prec...

The Journal of Cardiac Failure Publishes Results From Celladon Corporation's First-in-Human Phase 1/2 Clinical Trial in Advanced Heart Failure

...ecular therapies for the treatment of heart failure. The company's products target the key enzyme deficiency in advanced heart failure, SERCA2a, which regulates calcium cycling and contractility in heart muscle cells. Celladon's first product candidate, MYDICAR, delivers the gene for the SERCA2a enzyme. MYDICA...

Regional Biotech Association Warns Vermont Legislation Could Have Profound Negative Impact

...otech associations, companies, academic institutions, and other organizations consisting of more than 800 entities. Vermont law already heavily regulates biopharmaceutical marketing activities by requiring the disclosure of the value, nature and purpose of certain marketing related expenses by pharmaceu...
Regulates in Biological Products

13(S)-HODE-d4, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...nd mammalian lipoxygenases. It has been shown to inhibit the adhesion of tumor cells to the endothelium at concentrations around 1 µM, and down regulates the expression of the IRGpIIb/IIIa receptor....
Company:Cayman Chemical

13(S)-HODE-d4, Deuterium Conjugated/Tagged from Cayman Chemical

Description:...nd mammalian lipoxygenases. It has been shown to inhibit the adhesion of tumor cells to the endothelium at concentrations around 1 µM, and down regulates the expression of the IRGpIIb/IIIa receptor....
Company:Cayman Chemical

Rabbit Anti-SKAP55 Polyclonal Antibody, Unconjugated from ABR-Affinity BioReagents

Description:...Src kinase-associated phosphoprotein of 55 kDa (SKAP55) is expressed as a constitutively tyrosine phosphorylated 55-kD adapter protein that positively regulates TCR signaling. SKAP55 has also been shown to enhance adhesion to fibronectin and ICAM1, colocalize with F-actin at the T cell-antigen-presenting cell...
Company:ABR-Affinity BioReagents

Mouse Anti-CDX-2 Monoclonal Antibody, Unconjugated, Clone CDX2-88 from BioGenex

Description:... CDX2, a member of the caudal-related homeobox family, is an intestine-specific transcription factor that regulates both proliferation and differentiation in intestinal epithelial cells. It plays an important role in triggering cells towards the phenotype of differe...
Company:BioGenex

jetSI conc. 10 mM from Polyplus Transfection

Description:... described in: Z. Hassani, G.-F. Lemkine, P. Erbacher, G. Alfama, C. Giovannangeli, J.-P. Behr, and B.-A. Demeneix. Lipid-mediated siRNA delivery down regulates exogenous gene expression in the mouse brain at picomolar levels. J. Gene Med., 2005, 7, 198-207....
Company:Polyplus Transfection
Regulates in Biological Definition

Alternative splicing

...onsidered as a twofold information structure: A DNA sequence coding for the pre-mRNA An additional DNA code or other regulating process, which regulates the alternative splicing. There are four known modes of alternative splicing: Alternative selection of promoters : this is the only method o...

Apoptosis

.... If they would be let loose without any further processing, many could become autoreactive and attack healthy body cells. The way the immune system regulates this process is by "deleting" both the ineffective and the potentially damaging immature cells via apoptosis. As has just been described in the pre...

Cell nucleus

...uble membrane called the nuclear envelope . The inner and outer membrane fuse at regular intervals, forming nuclear pores . The nuclear envelope regulates and facilitates transport between the nucleus and the cytoplasm, while separating the chemical reactions taking place in cytoplasm from reactions happ...

Cell growth

...ution of Wee1 protein in cells as they grow larger. Cell size regulation in mammals The protein mTOR is a serine/threonine kinase that regulates translation and cell division. Nutrient availability influences mTOR so that when cells are not able to grow to normal size they will not undergo ce...

Diabetes mellitus

...132 billion in the United States alone every year. Causes and types The role of insulin Since insulin is the principal hormone that regulates uptake of glucose into cells (primarily muscle and fat cells) from the blood, deficiency of insulin or its action plays a central role in all forms ...

Endodermis

... Endodermis is the bottom layer of skin . In plants, it is a thin layer of parenchyma found in roots , just outside the vascular cylinder. It regulates the flow of water. Endodermis is tightly packed together and contains Casparian strips on their radial walls which are made of suberin mainly, a waxy ...
Regulates in Biological Dictionary

Untranslated RNA

...he... DsrA is a small untranslated RNA that regulates expression of two global ... The untranslated RNA DsrA regulates at least two global regulatory networks by ... ... within viral 3' untranslated RNA pseudoknots regulates translation. ... ... whose products are small ...

Tricuspid valve

...he heart. It's relatively a rare condition. The stenosis causes increased resistance to blood flow through the valve . The tricuspid valve regulates blood flow from the heart's upper-right chamber to the lower-right chamber. ... Damage to the tricuspid valve may be caused by ... Tricuspid ...

Spliceosome

...hypothesis that the spliceosome is ... Mechanical Devices of the Spliceosome : Motors, Clocks, Springs, and Things ... EF-G-like GTPase Snu114p regulates Spliceosome Dynamics Mediated by Brr2p, a ... ... spliceosome , a big ribonucleoprotein particle composed of some 300 proteins and five RNAs. ...

SnRNA

...credit card req'd. Find Journal of the Tennessee Academy of Science articles plus many other academic journal articles, magazine arti... U1 snRNA regulates Initiation of Transcription in Eukaryotes. ... Figure 4: U1 snRNA stimulates TFIIH-dependent abortive initiation by RNA polymerase II: ... ... ...

Sigma Factor

... sigmaX in Streptococcus pyogenes is ... A secondary RNA polymerase sigma factor from Streptococcus pyogenes ... ... by sigma factors ... regulates the sigma factors ? Not transcriptional ... Sigma factors in sporulation. Old gene names New gene names Protein ... ... suggest that con...

Sequential Epitope

... a sequential epitope is an epitope that is recognized by antibodies ... ... La/SSB epitope anchored to Sequential Oligopeptide Carrier regulates ... This carrier, named Sequential Oligopeptide Carrier, SOC(n), formed by the ... The longest sequential stretch of identified residues per e...
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(Date:7/30/2014)... truffle uses reversible epigenetic processes to regulate its genes, ... - a picture of the genome regulation taking place ... journal Genome Biology and illustrates how the ... ,jumping genes,. The authors say this may shed light ... , Black truffles (Tuber melanosporum), also known as Prigord ...
(Date:7/30/2014)... effects of climate change on the world,s animal ... factors, according to a new paper by a ... of Queensland, and other organizations. The authors claim ... the point when it comes to climate change. ... scientists focus on the "direct" threats of changing ...
(Date:7/30/2014)... Antonio Life Sciences Institute (SALSI), a joint venture between ... The University of Texas Health Science Center at San ... Pilot Program. The winners, Emily Boice from UTSA and ... $25,000 for their project titled, "Novel engineered ferritins for ... , Boice and Huang,s research is focused on finding ...
Breaking Biology News(10 mins):How black truffles deal with the jumpers in their genome 2Conservation scientists asking wrong questions on climate change impacts on wildlife 2
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