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Receptor in Medical News

Eliminating Cell Receptor Prevents Infections in Animal Study

PHILADELPHIA, July 22 /PRNewswire-USNewswire/ -- New research from The Children's Hospital of Philadelphia sheds light on the role of cell receptors in acting as gatekeepers for infectious viruses. By using mice genetically engineered to lack a particular receptor in heart and pancreas c...

JNCI news brief: Breast cancer hormone receptor status and risk of a second primary tumor

Women with hormone receptor (HR) negative first tumors have twice as much risk for developing a second breast cancer as women with HR-positive tumors, according to a study published online July 9 in the Journal of the National Cancer Institute . Christina A. Clarke, Ph.D., of the Northern Cali...

Variants of 'umami' taste receptor contribute to our individualized flavor worlds

PHILADELPHIA (July 8, 2009) -- Using a combination of sensory, genetic, and in vitro approaches, researchers from the Monell Center confirm that the T1R1-T1R3 taste receptor plays a role in human umami (amino acid) taste. They further report that variations in the genes that code for this rec...

Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer

PROVIDENCE, RI New research at Rhode Island Hospital has uncovered the biological effects of a novel membrane estrogen receptor, a finding that has potential implications for hormonal therapy for breast cancer. The study is published in the July edition of the journal Molecular Endocrinology. T...

Adenoviral vector specifically targeted to EphA2 receptor in pancreatic cancer cells

Pancreatic cancer is a devastating disease with poor prognosis. This warrants the development of novel therapies including gene therapy. However, clinical studies have demonstrated poor efficacy of adenoviral gene therapy because of the absence of adenoviral binding sites on pancreatic cancer cell...

Amira Pharmaceuticals to Present Preclinical Data from LPA1 Receptor Antagonist Program at FASEB Summer Research Conference

SAN DIEGO, June 15 /PRNewswire/ -- Amira Pharmaceuticals, Inc. announced today that it will present preclinical data from its LPA1 receptor antagonist program on June 30, 2009 at the Federation of American Societies for Experimental Biology (FASEB) Summer Research Conference in Carefree, Arizona...

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Receptor in Medical Technology

Bionovo's Estrogen Receptor Beta Selective Drugs Have Unique Gene Expression and Cell Type Specificity

EMERYVILLE, Calif., July 17 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI ) announced today that a study of the gene regulation in multiple cell lines by several of their estrogen receptor beta (ERb) candidates will be published in Public Library of Science One. ...

One Step Closer: Novel Opioid Receptor Compound in Phase I Clinical Trials

TROY, N.Y., May 8 /PRNewswire-USNewswire/ -- For more than 10 years, Mark Wentland, professor of chemistry and chemical biology at Rensselaer Polytechnic Institute , led a Rensselaer team in the discovery of a family of novel opioid receptor compounds with the potential to treat nervous system di...

Schering-Plough's Investigational Oral Thrombin Receptor Antagonist Meets Primary Endpoint in a Newly Published Study

A Phase II Study Published in The Lancet of Fast-Tracked Antiplatelet Agent Showed No Increase in TIMI Major and Minor Bleeding and was Well Tolerated When Given With Standard Platelet Therapy KENILWORTH, N.J., March 12 /PRNewswire-FirstCall/ -- Results of a Schering-Plough Corporation (NYSE:...

Nventa Presents Findings on Proprietary Toll-like Receptor 3 (TLR3) Agonist, Poly-ICR, at World Vaccine Congress

Findings Confirm Potency of Poly-ICR as Vaccine Adjuvant SAN DIEGO, Oct. 8 /PRNewswire-FirstCall/ -- Nventa Biopharmaceuticals Corporation (TSX: NVN) today presented positive data from preclinical studies using its proprietary Toll-like Receptor 3 agonist, Poly IC-Poly Arginine (Poly-I...

AEterna Zentaris Reaches 2nd Stage of Patient Recruitment for Phase 2 Trial in Ovarian Cancer with the Innovative LHRH Receptor Targeted Conjugate, AEZS-108

QUEBEC CITY, Oct. 2 /PRNewswire-FirstCall/ - AEterna Zentaris Inc. (NASDAQ: AEZS ; TSX: AEZ), a global biopharmaceutical company focused on endocrine therapy and oncology, today reported that it has entered the second stage of patient recruitment for its Phase 2 trial in ovarian cancer with A...

Bionovo Elucidates Mechanism of Breast Cancer Control by Estrogen Receptor Beta

- Results Presented at Endocrine Society's 90th Annual Meeting - SAN FRANCISCO and EMERYVILLE, Calif., June 16 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI ) today announced results on the role of estrogen receptor beta in breast cancer growth regulation. The data, which were pre...

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Receptor in Medical Products

TSH Receptor Antibody

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Transferrin Receptor Level

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Thyroid Stimulating Hormone Receptor Antibody (TRAb)

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Steroid Receptor Assay (Paraffin)

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Neutrophil Receptor Profile

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

Estrogen/Progesterone Receptor Assay, Paraffin

Description: ARUP Laboratories is a national reference laboratory and a worldwide leader in innovative laboratory research and development. ARUP offers an extensive test menu of highly complex and unique medical tests in clinical and anatomic pathology. Owned by the University of Utah, ARUP Laboratories' client...
Company:ARUP Laboratories

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Receptor in Medical Dictionary

Vasodilation

... BK promotes vasodilation ,1 exerts antiproliferative effects,2 inhibits thrombin ... Although BK is known to cause vasodilation through the B2 receptor and through ... Britannica online encyclopedia article on vasodilation (physiology), ACh affects a number of body systems including the cardiov...

Taste

...ok Ground Venison BBQ ... Humans can recognize five tastes : bitter, salty, sour, sweet and umami. ... Now, researchers have identified a taste receptor that responds to amino acids, ... Featuring over 30 local restaurants, a live Iron-Chef competition, Family Sports Zone, local and national music ...

Sweeteners

...ravings ... ALTERNATIVE SWEETENERS ... ARTIFICIAL SWEETENERS ... SWEETENERS . Carbohydrate MiniTopics. Carbohydrates. Elmhurst College. Sweet receptor Site ... All carbohydrate sweeteners (sugar, evaporated cane juice, ... ...

Polyuria

...an urinary... fluid intake: Thirst will usually accompany polyuria . ... Polyuria is a fairly common symptom, which is often noticed when ... D receptor produces polyuria by increasing thirst... of polyuria and diabetes ... Children with Growth hormone deficiency,congenital adrenal hyperpla...

Pharmacology

...niversity Department of Pharmacology and Toxicology. Our goal is to provide the background and skills necessary to enable our graduate ... Sigma receptor pharmacology , ... Assistant Professor of Pharmacology and RIPS, ... Professor in Pharmacology . ... ... a Visiting Professorship in Pharmaco...

Olfactory

...d of the Day, and word games. Each olfactory receptor cell possesses only one type of odorant receptor...ry ... Gated currents in isolated olfactory receptor neurons of the ... Trotier D, MacLeod P. Intracellular recordings from salamander olfactory receptor cells. ... The mechanism of excitatory olfact...
Receptor in Biological News

Grant supports LSUHSC research on how like cell receptor systems determine very different functions

New Orleans, LA Andy Catling, PhD, Associate Professor in the Department of Pharmacology and the Stanley S. Scott Cancer Center at LSU Health Sciences Center New Orleans, has been awarded a $177, 500 supplement to his RO1 grant by the National Institute of General Medical Sciences to support his ...

Newly discovered epidermal growth factor receptor active in human pancreatic cancers

Finally some promising news about pancreatic cancer, one of the most fatal cancers, due to the difficulties of early detection and the lack of effective therapies: Johns Hopkins University pathologist Akhilesh Pandey has identified an epidermal growth factor receptor aberrantly active in approxima...

'New' estrogen receptor found to be key player in tamoxifen resistance

Washington, D.C. Researchers at Georgetown University Medical Center have discovered a novel way in which breast cancer cells become resistant to tamoxifen, the world's largest-selling breast cancer prevention and treatment drug. They say the findings could provide a way to identify tamoxifen us...

Variant of vitamin D receptor gene linked to melanoma risk

A new analysis indicates an association between a gene involved in vitamin D metabolism and skin cancer. Published in the November 1, 2008 issue of CANCER , a peer-reviewed journal of the American Cancer Society, the study suggests that individuals with certain variants in a vitamin D-related gen...

'Knocking out' cell receptor may help block fat deposits in tissues, prevent weight gain

CINCINNATIUniversity of Cincinnati (UC) pathologists have identified a new molecular target that one day may help scientists develop drugs to reduce fat transport to adipocytes (fat cells) in the body and prevent obesity and related disorders, like diabetes. Detailed in the Oct. 18 online edit...

Study reveals a reprogrammed role for the androgen receptor

BOSTONThe androgen receptor a protein ignition switch for prostate cancer cell growth and division is a master of adaptability. When drug therapy deprives the receptor of androgen hormones, thereby halting cell proliferation, the receptor manages to find an alternate growth route. A new study by...

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Receptor in Biological Technology

Bionovo Publishes Discoveries in Predictable Tissue Selectivity for Selective Estrogen Receptor Modulators Platform

EMERYVILLE, Calif., Jan. 2 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI ) announced today results describing predictable estrogen regulatory elements that can be used to identify estrogenic drugs that are safer. The data, published in Molecular and Cellular Endocrinology, showed tha...

AEterna Zentaris Reaches 2nd Stage of Patient Recruitment for Phase 2 Trial in Endometrial Cancer with the Innovative LHRH Receptor Targeted Conjugate, AEZS-108

QUEBEC CITY, Nov. 3 /PRNewswire-FirstCall/ - AEterna Zentaris Inc. (NASDAQ: AEZS ; TSX: AEZ), a global biopharmaceutical company focused on endocrine therapy and oncology, today reported that it has entered the second stage of patient recruitment for its Phase 2 trial in endometrial cancer wi...

Genomic Health Announces Expansion of Oncotype DX(R) Breast Cancer Test to Include Quantitative Estrogen Receptor (ER) and Progesterone Receptor (PR) Scores

Study Published in the Journal of Clinical Oncology Proves Accurate Measurement of ER and PR Status Using Quantitative Reverse-Transcriptase Polymerase Chain Reaction (RT-PCR) REDWOOD CITY, Calif., June 2 /PRNewswire-FirstCall/ -- Genomic Health, Inc. (Nasdaq: GHDX ) tod...

Arena Pharmaceuticals Announces Initiation of Phase 1 Clinical Trial of Second Generation Niacin Receptor Agonist Under Its Collaboration With Merck & Co., Inc.

SAN DIEGO, Jan. 25 /PRNewswire-FirstCall/ -- Arena Pharmaceuticals, Inc. (Nasdaq: ARNA ) announced today that Merck & Co., Inc. initiated a Phase 1 clinical trial of a second generation oral niacin receptor agonist under a collaboration between the companies to discover drugs for the treatmen...

ChemoCentryx Demonstrates Recently Discovered Chemokine Receptor CXCR7 is Essential in Tumor Growth

Characterization of Receptor's Central Role in Cancer is Published in the Proceedings of the National Academy of Sciences MOUNTAIN VIEW, Calif., Sept. 26 /PRNewswire/ -- ChemoCentryx, Inc., a clinical-stage biopharmaceutical company focused on discovering, developing and commercializ...

MedImmune Advances Asthma Program With Start of Phase 2 Clinical Trial for Antibody Targeting IL-5 Receptor

GAITHERSBURG, Md., Dec. 4 /PRNewswire/ -- MedImmune today announced that it has initiated a Phase 2 clinical trial in patients with chronic asthma to determine the safety of subcutaneous dosing of a humanized monoclonal antibody (MAb) that targets the interleukin-5 receptor (IL-5R). Preclinical da...

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Receptor in Biological Products

Mouse Anti-nicotinic Acetylcholine Receptor Monoclonal Antibody, Unconjugated, Clone 88B from Abcam

Description: Mouse monoclonal [88B] to nicotinic Acetylcholine Receptor ( Abpromise for all tested applications)....
Company:Abcam

Rabbit Anti-Rat Glutamate Receptor 5/1a Polyclonal Antibody, Unconjugated from Exalpha Biologicals, Inc.

Description: Glutamate Receptor 5/1a...
Company:Exalpha Biologicals, Inc.

Mouse Anti-Prostaglandin-E2 receptor EP2/EP3 Monoclonal Antibody, Unconjugated, Clone 3F12 from Exalpha Biologicals, Inc.

Description: Prostaglandin-E2 receptor EP2/EP3 Market Segment: GPCRs...
Company:Exalpha Biologicals, Inc.

Anti-Neurotensin Receptor Monoclonal Antibody, Unconjugated , Clone B-N6 from Cell Sciences

Description: Request Info...
Company:Cell Sciences

Anti-Dopamine D2 / D3 Receptor Polyclonal Antibody, Unconjugated from CHEMICON

Description: Dopamine D2 and D3 receptor, human and possibly mouse. AB1502 detects 40 ng of dopamine receptor peptide by ELISA. AB1502 is not neutralizing....
Company:CHEMICON

Rabbit Anti-Human Macrophage-stimulating protein receptor Polyclonal Antibody, Unconjugated from GenWay Biotech, Inc.

Description: Macrophage-stimulating protein receptor...
Company:GenWay Biotech, Inc.

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Receptor in Biological Definition

Receptor

Receptor may refer to: In telecommunication , a receiver . In physiology , a sensory receptor is any structure which, on receiving environmental stimuli, produces an informative nerve impulse . In biochemistry , a receptor is a protein molecule that receives and responds t...

Transmembrane receptor

Transmembrane receptors are integral membrane proteins , which reside and operate typically within a cell's plasma membrane , but also in the membranes of some subcellular compartments and organelles . Binding to a signalling molecule or sometimes to a pair of such molecules on one side of ...

Apoptosis

...embryonic neural tube: cells that receive Shh in a receptor in their membranes called Patched1 (Ptc1) survive ... absence of Shh, one of the ends of this same Ptc1 receptor (the carboxyl-terminal, inside the membrane) is cl... These studies show how critical is the role of PS receptor (PSR) in the development of complex organisms such...

B cell

...arrow , where B cells are produced in all other vertebrates. The human body makes hundreds of different types of B cells, and each type has a unique receptor protein on its membrane that will bind to one particular antigen; at any one time in the human body millions of B cells are circulating in the blood ...

Cancer

...oth experience a reduced incidence of prostate cancer in comparison to men taking placebo pills. Daily use of tamoxifen , a selective estrogen receptor modulator, for up to 5 years, has been demonstrated to reduce the risk of developing breast cancer in high-risk women by about 50%. Cis-retinoic ac...

Developmental biology

...y signal transduction pathways that relay signals from outside of cells to the cell nucleus. Signal transduction pathways often involve receptors , receptor ligands and enzymes such as tampons. One key class of genes that are differentially regulated by transcription factors in different cell types are g...
Receptor in Biological Dictionary

Receptor

In biochemistry, a receptor is a protein molecule, embedded in either the plasma membrane or cytoplasm of a cell, to which a mobile signaling (or "signal") molecule may attach. A molecule which binds to a receptor is called a... The androgen receptor (AR), also known as...

Transmembrane receptor

Membrane or Transmembrane receptors are specialized integral membrane proteins that take part in communication between the the cell and the outside world. Extracellular signaling molecules attach to the receptor , triggering... G protein-coupled receptors (GPCRs), also known as seven- tra...

Transferrin receptor

Transferrin receptor (TfR) is a carrier protein for transferrin . It is needed for the import of iron into the cell and is regulated in response to intracellular iron concentration. Low iron concentrations promote increased levels of transferrin receptor , to increase iron intake into t...

Zona pellucida

...nding of sperm to the zona pellucida is a receptor-ligand interaction with a ... The same zona pellucida protein that serves as a sperm receptor also stimulates ... The zona pellucida binding assay assesses the ability of ... to spermatozoa on subsequent sperm– zona pellucida bind .....

Vestibular system

... balanced system . ... The purpose of the vestibular system is to keep tabs on the position ... The vestibular system is divided into two receptor organs to accomplish these tasks. ... The vestibular apparatus or vestibular system , or balance system , is the sensory ... Accordingly, ou...

Transduction

...eceptors by structural changes ... Signal transduction will involve a receptor for the first messenger and may ... Thus, muscarinic cholinergic transduction at all five muscarinic receptor ... 'Signal Transduction ' or 'Signaling' is the process by which biol...
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(Date:8/28/2014)... Ariz. (PRWEB) August 28, 2014 Arizona ... Force Impact Technologies , has been named one of ... the Year competition. , This is the fourth consecutive ... in the competition. Jared Schoepf, co-founder of SafeSIPP, and ... 2013 and 2012, respectively. In 2011, ASU dominated the ...
(Date:8/28/2014)... Reinberg HealthDay Reporter THURSDAY, ... the diet may worsen symptoms of multiple sclerosis (MS), a ... MS, such as vitamin D, smoking and Epstein Barr virus ... another environmental factor affecting MS patients," said lead researcher Dr. ... in Buenos Aires. Multiple sclerosis is a disease of ...
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(Date:8/28/2014)... Norton HealthDay Reporter THURSDAY, ... sending electrical currents through the scalp to a specific network ... a day. In a small study of healthy young ... certain networks involved in memory. That, in turn, boosted participants, ... after the brain stimulation. During TMS, an electromagnetic coil ...
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(Date:8/28/2014)... This news release is available in German . ... electronic products are now built with the help of sophisticated ... are fixed, are an important part of these assembly lines. ... are attached in various work stages arranged in a precise ... the end of the line. , The creation of such ...
(Date:8/28/2014)... Munich have assigned a number of 435-million-year-old fossils ... animals lived in shallow marine habitats and were ... Jurassic strata. , Before they sank to ... were fossilized some 435 million years ago, these ... seas although they were not exactly inconspicuous, ...
(Date:8/27/2014)... of the human genome was unveiled today in the ... comparison yet of how the genomes of the fruit ... appearing August 28 in in the journal Nature ... species, genomes is "read out," and how their DNA ... add billions of entries to a publicly available archive ...
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