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Scientists ID molecular 'switch' in liver that triggers harmful effects of saturated and trans fats

Dana-Farber Cancer Institute researchers have identified a molecular mechanism in the liver that explains, for the first time, how consuming foods rich in saturated fats and trans-fatty acids causes elevated blood levels of cholesterol and triglycerides and increases one's risk of heart disease and certain cancers. In the Jan. 28 issue of Cell, scientists led by Bruce Spiegelman, PhD, rep...

Anti cancer virotherapy well tolerated in first human administration, research finds

An international medical conference here heard that an Australian developed anti-cancer therapy based on the use of a common cold virus to control cancer cell growth has begun safety testing in human subjects. The research was presented to the third International Meeting on Replicating Oncolytic Virus Therapeutics, on Friday 11 March by Newcastle University associate professor, Darren Sha...

Navigating an integrated yeast network

Scientists have for the first time mapped multiple complex biological interactions in a yeast cell in a simple graphical form, enhancing our understanding of how the networks of interaction by which components of a cell influence one another. New research published in the Open Access journal Journal of Biology shows that such maps can also reveal cryptic interactions and enable accurate predictio...

To Stop Evolution: New Way Of Fighting Antibiotic Resistance Demonstrated By Scripps Scientists

A team of scientists at The Scripps Research Institute and the University of Wisconsin have demonstrated a new way of fighting antibiotic resistance: by stopping evolution. In the June issue of the open-access journal PloS Biology, the team describes how a protein called LexA in the bacterium Escherichia coli promotes mutations and helps the pathogen evolve resistance to antibiotics. The...

For first time, brain cells generated in a dish

Regenerative medicine scientists at the University of Florida's McKnight Brain Institute have created a system in rodent models that for the first time duplicates neurogenesis -- the process of generating new brain cells -- in a dish. Writing in today's (June 13) Proceedings of the National Academy of Sciences, researchers describe a cell culture method that holds the promise of producing...

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YSI 2300 STAT Plus Glucose & Lactate Analyzer from YSI Incorporated

Description:The gold standard for whole-blood clinical diagnostic work in hospitals and laboratories. In 60 seconds or less, this analyzer makes precise glucose measurements of whole blood, plasma, or serum and precise lactate measurements of whole blood, plasma, or cerebrospinal fluid. The analyzer's hematocrit correction option allows you to have glucose results expressed as plasma even when running whole...
Company:YSI Incorporated

DH-2000 with integrated shutter from Ocean Optics

Description:Identical to the DH-2000, but comes with a shutter (controlled via a TTL signal or switch up to 5 Hz) The DH-2000 Deuterium Tungsten Halogen Light Source combines the continuous spectrum of deuterium and tungsten halogen light sources in a single optical path. The combined-spectrum light source produces a powerful, stable output from 215-200 nm. In addition, deep-UV versions of the light...
Company:Ocean Optics

D-2000 with integrated shutter from Ocean Optics

Description:Identical to the D-2000, but comes with a shutter (controlled via a TTL signal or switch) The D-2000 Deuterium Light Source produces a powerful, stable output from 215-400 nm. In addition, deep-UV versions of the light source are available, providing a wavelength range of 190-400 nm. This powerful and stable lamp provides peak-to-peak stability of less than 0.005% and drift of only +/-0....
Company:Ocean Optics

D-2000-DUV with integrated shutter from Ocean Optics

Description:Identical to the D-2000, except that it uses a deep-UV deuterium bulb, which provides a 190-400 nm wavelength range and comes with a shutter (controlled via a TTL signal or switch) The D-2000 Deuterium Light Source produces a powerful, stable output from 215-400 nm. In addition, deep-UV versions of the light source are available, providing a wavelength range of 190-400 nm. This powerful a...
Company:Ocean Optics

DH-2000-DUV with integrated shutter from Ocean Optics

Description:Identical to the DH-2000, except that it uses a deep-UV deuterium bulb, which provides a 190-1700 nm wavelength range and comes with a shutter (controlled via a TTL signal or switch up to 5 Hz) The DH-2000 Deuterium Tungsten Halogen Light Source combines the continuous spectrum of deuterium and tungsten halogen light sources in a single optical path. The combined-spectrum light source pro...
Company:Ocean Optics

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rated at Biology Technology

Fractionating DNA Fragments Generated by Differential Display PCR

Pfizer Central Research, Sandwich, UK. 01304 618482 Differential display PCR (DDPCR) is a widely used technique foridentifying genes differentially expressed between cell types. Application ofDDPCR to allergic disease provides a potential means for elucidating themechanisms involved in allergic...

Why can't your computer get frustrated, too?

Should the co...

Nebraska bank benefits from Fiservs integrated solutions

Brookfield, Wis. A Midwestern community bank can now remove the guesswork out of customer profitability analyses, based on the integration of two technologies from two separate divisions of Wisconsin-based Fiserv. , located in Laurel, Nebraska, can now view financial relationship data from any of its desktops and ident...

Advancing the quality control methodology to assess isolated total RNA and generated fragmented cRNA

This Application Note describes how Gene Logic, Inc., has improved itsability to analyze the quality of total RNA and fragmented cRNA by usingthe Agilent 2100 bioanalyzer. The Eukaryote Total RNA Nano and Picoassays are currently being utilized to examine the 28S/18S ratio...

Inducing RNAi with siRNA Cocktails Generated by RNase III

Ambion, Inc. Austin, TX 78744-1832 Small interfering RNA (siRNA) is an extremely...

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Radiation Therapy for Prostate Cancer Tolerated Well by Elderly Patients

Researchers from the University of Pittsburgh Medical Center treated 33 prostate cancer patients, over age 80, with external beam radiation therapy. // Patients received the same radiation doses that patients in their 50s and 60s receive. Results of the study show the elderly patients had a five-year survival rate of more than 60 percent. Researchers say these patients experienced no unu...

Effective Treatment Option For Dehydrated Kids

Fluids given orally are better than intravenous fluids for children who are dehydrated say researchers according to a recent study .// Oral rehydration therapy is recommended for children with mild to moderate dehydration. However, a recent survey reveals that most pediatric emergency medicine physicians do not use this therapy instead they use intravenous methods, which are performed by...

Biomarker for prostate cancer may be separated for treatment

Scientists at UCLA had been able to isolate a biomarker for prostate cancer cells do// that it will become easier to treat the disease. The biomarker protein, which was hidden inside the cells, can now be moved to a different location from where it can go into the blood. This will make it possible for the medical professionals to treat the prostate cancer disease with both chemotherapy...

Sensations Generated By Cocaine And Methamphetamine Abuse Are Not Same.

Investigators from UCLA had found that the there is a marked difference between the sensations generated by cocaine and methamphetamine use in onset, pattern and duration of their “highs”. // The study shows that subjective, or self-reported, responses to cocaine peak and decline more rapidly than those of methamphetamine. Cardiovascular responses to the two stimulants are similar at...

Indian Doctor Wants March 21st To Be Celebrated As World Down Syndrome Day

Balbir Singh, president of Down Syndrome International (DSI), is an Indian origin Singapore doctor who got involved in the Down Syndrome fraternity after the birth of his daughter Jaspreet 25 years ago who had Down’s syndrome. Down Syndrome Association (DSI) Singapore, founded by Singh// some 25 years ago, on talking in the Southern African Conference on Down Syndrome and Intellectual Dis...

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Gas operated stool without castors

Description:A sturdy, robust stool. Gas operated height adjustment for convenience....
Company:Haag-Streit UK

Gas operated stool with castors

Description:A sturdy, robust stool. Gas operated height adjustment for convenience....
Company:Haag-Streit UK

L'Anthony's Desaturated 15 Hue Test

Description:The L'Anthony 15 disc test (P/N LD15C) include a durable laminated score template for copying, and comprehensive instructions. P/N LD15C also includes a Plexiglas Case and a supply of finger tip covers for the test subjects fingers ( to maintain cleanliness and accuracy of the color discs). Beware that these finger cots are made with latex....
Company:Richmond Products, Inc.

Magnetic LAnthony 15 desaturated Kit (4 lbs)

Description:Magnets move the color disks, Protects Disks from fingerprints, Keeps all the disks in one place, Clear glass insures accurate color perception, Makes Color testing fun....
Company:Richmond Products, Inc.

Bausch & Lomb Concentrated Cleaner

Description:Bausch & Lomb concentrated cleaner is a sterile, concentrated homogeneous surfactant solution containing alkyl ether sulfate, ethoxylated alkyl phenol, tri-quaternary cocoa-based phospholipid and silica gel as cleaning agents....
Company:Bausch & Lomb, Inc.

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rated at Medicine Technology

Study Shows Ixabepilone Demonstrated Clear Activity in Patients with Metastatic Breast Cancer Resistant to Anthracycline, Taxane, and Capecitabine

- Phase II Results Published in the Journal of Clinical Oncology - NEW YORK, July 06, 2007 /PRNewswire-FirstCall/ -- Results from aPhase II study - which will be published in the August 10, 2007issue of the Journal of Clinical Oncology (JCO) and are nowavailable as an Early Release Article at <a target="_blank" href="http://www.jco.org/">www.jco.org - demonstrate thatixabepilone, a Br...

Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic Control in Subjects with Type 2 Diabetes Compared to Metformin Alone

-- Additional Findings Reported Safety & Tolerability Profilein Subjects with Type 2 Diabetes and Healthy Subjects -- CHICAGO, June 25, 2007 /PRNewswire-FirstCall/ -- Phase III datapresented this week at the annual meeting of the American DiabetesAssociation demonstrated that saxagliptin, an inhibitor ofdipeptidyl-peptidase-4 (DPP-4) in development by Bristol-MyersSquibb Company and A...

Data Demonstrated Saxagliptin Added to Metformin Improved Glycemic Control in Subjects with Type 2 Diabetes Compared to Metformin Alone

Additional Findings Reported Safety & Tolerability Profilein Subjects with Type 2 Diabetes and Healthy Subjects CHICAGO, June 25 /PRNewswire-FirstCall/ -- Phase III datapresented this week at the annual meeting of the American DiabetesAssociation demonstrated that saxagliptin, an inhibitor ofdipeptidyl-peptidase-4 (DPP-4) in development by Bristol-MyersSquibb Company (NYSE: BMY...

Investigational Study Demonstrated a Re-Establishment of Clinical Improvement with Orencia (Abatacept) in Children with Juvenile Idiopathic Arthritis upon Re-Introduction of Therapy

BARCELONA, Spain, June 15, 2007 /PRNewswire-FirstCall/ --Bristol-Myers Squibb Company today announced results regarding theefficacy and safety of ORENCIA(R) (abatacept) from the open-labelphase of an ongoing investigational study in children with juvenileidiopathic arthritis (JIA) who have had an inadequate response toone or more disease-modifying anti- rheumatic drugs (DMARDs), suchas m...

Study Demonstrated Rozerem (ramelteon) Does Not Affect Middle-of-the-Night Balance in Older Adults with Insomnia

MINNEAPOLIS, June 13, 2007 /PRNewswire/ -- Two studies presentedtoday demonstrated that Rozerem did not affect body sway at peakplasma levels, nor did it impair middle-of-the-night balance,mobility or memory performance in patients who suffer from chronicinsomnia. The results of the studies were presented at the 21stAnnual Meeting of the Associated Professional Sleep Societies(APSS)....

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