X chromosome exposed

...e at EMBL-EBI have uncovered how one component of the MSL complex, an enzyme called MOF, ensures that the activity of only male X chromosome genes get ratcheted up. MOF relaxes the structure of chromatin tightly packaged DNA, to allow the transcription machinery to access genes on the DNA. We were very sur...

ratcheted in Biological Technology

Return of Retention

...rom flex time to foosball, quickly disappeared. Even cost-free pats on the back became rare as performance pressures on managers and staff continually ratcheted up, leaving little time or energy for this most basic of retention measures. Many workers are disenchanted with the grim and depressing corporate e...

Though VC investing is down, reloading on new funds is rising

...at this juncture, lets take a glimpse at the number of deals and deal size by company stage of development. Its obvious that deal sizes have ratcheted down substantially at all levels over the six-year period with the biggest drop in the start-up and seed segment. Likewise, the number of all over dea...

BIO 2006 aftermath and a taste of bio-generics

...eying for worldwide position in the generic market by several major players: 1. Teva Pharmaceuticals - Headquartered outside of Tel Aviz, Israel, ratcheted up its worldwide presence by the acquisition of fellow generic company IVAX last year and Sicor the year before. 2. Sandoz Pharmaceuticals (a div...