Navigation Links
radiolabeled in Medical News

Peregrine Pharmaceuticals Reports Financial Results for Fiscal Year 2009

...tech. Medibiotech is a Chinese company that has the exclusive rights in the People's Republic of China to develop and market a version of Peregrine's radiolabeled tumor necrosis therapy (TNT) technology for the treatment of cancer. Peregrine will also make certain cash payments to CTL. In March 2009, Pere...

Remote-control closed system invented for inserting radio-active atoms inside fullerenes

...red solution contains Lu atoms bound to nitrogen inside of fullerenes. This radiolabeled nanomaterial is then further purified by passage through a column that tra...worked out, Dorn is confident the generator will work just as well with the radiolabeled product and will produce (177Lu3N@C80). It all takes less than a day, wh...

Cell transplantation and cardiac repair

...o different delivery techniques through the anterograde intra-coronary (ICA) or via the retrograde intra-coronary artery vein (ICV). Researchers used radiolabeled cells to evaluate cell distribution patterns in the heart and their relationship with left ventricle function improvement. "BMMNC retention by damag...

Case Western Reserve University Receives $5M From Third Frontier Commission for the Center for Stem Cell & Regenerative Medicine

... Zhenghong Lee (UHCMC) and Jeremy Rich (CC) will collaborate to develop a method to non-invasively image cancer stem cells through the development of radiolabeled tracers. The CSCRM Administration, led by Debra Grega and Michael Gilkey, is responsible for coordinating, accounting and reporting...

Isis Highlights New Clinical Data on Anti-Cancer Antisense Drugs Featured at ASCO

...of Manchester, presented results of a pharmacokinetic study of LY2181308 in patients with cancer. Using state-of-the-art imaging techniques to assess radiolabeled LY2181308 distribution in humans, Dr. Saleem reported that LY2181308 effectively penetrated tumor tissues. LY2181308 is currently being evaluated in ...

Seahorse XF96 Extracellular Flux Analyzer Wins Best New Product Award for DRUG DISCOVERY at 2009 Molecular Medicine Conference

...le to perform these complex bioenergetic assays in a 96-well microplate. XF Analyzers replace Clark-type electrodes, oxygen or pH sensitive dyes, and radiolabeled substrates. "Prior to the introduction of our XF instruments the standard method for oxygen measurements was using a Clark electrode, invented in...

Bradmer to present poster on progression free survival and overall survival data from Neuradiab(TM) Phase II trials at Society for Neuro-Oncology Meeting

...glassarttrial.com ) The Phase III GLASS-ART Trial derives its name from its description: GBM Locoregional Agent Survival Study - Antitenascin radiolabeled antibody Therapy Trial. The study is designed to determine the survival benefit derived from, and safety of, adding Neuradiab to the current standard ...

Bradmer to present at Rodman & Renshaw Healthcare Conference

...://www.glassarttrial.com ) The Phase III GLASS-ART Trial derives its name from its description: GBM Locoregional Agent Survival Study - Antitenascin radiolabeled antibody Therapy Trial. The study is designed to determine the survival benefit derived from, and safety of, adding Neuradiab to the current standard ...

Peter Ell receives SNM's Georg Charles de Hevesy Nuclear Pioneer Award

...human IgG), a type of antibody that circulates in the blood and recognizes foreign particles that might be harmful, as well as iodobenzamide (IBZM), a radiolabeled probe that binds to the cerebral dopamine receptor and is used in neurotransmission studies and SPECT. "It is an overwhelming delight and honor to ...

LSUHSC inventor awarded patent for new procedure to detect cancer spread

...hat the procedure which consists of injection of a radiolabeled dye around a cancer can identify sentinel nodes th...pound, a vital dye, or both. When both a dye and a radiolabeled carrier are used, they have been injected separately. The radiolabeled carrier substance is injected either the afternoon...
radiolabeled in Medical Technology

Covance Announces Integrated Radiolabeled Clinical Pharmacology Studies

--Integrated human AME studies comply with recent FDA guidance for earlier testing-- PRINCETON, N.J., June 23 /PRNewswire/ -- Covance Inc. today announced its integrated radiolabeled clinical pharmacology studies in compliance with Food and Drug Administration (FDA) guidance on Metabol...

Immunomedics Announces Preclinical Therapy Results of SN-38 Immunoconjugate for Colorectal Cancer

...dy that binds to the carcinoembryonic antigen (CEACAM5) expressed by many solid cancers. The Company has conducted clinical trials with the naked and radiolabeled antibody in patients with colorectal, breast and pancreas cancers. In a lung metastatic model of colon carcinoma, therapy with labetuzumab-SN-3...

Bradmer reports progression free survival data from previous Phase II glioblastoma multiforme trials

...://www.glassarttrial.com ) The Phase III GLASS-ART trial derives its name from its description: GBM Locoregional Agent Survival Study - Antitenascin radiolabeled antibody Therapy Trial. The study is designed to determine the survival benefit derived from, and safety of, adding Neuradiab(TM) to the current stand...

Phase 1/2 Trial of Motexafin Gadolinium Plus Antibody Targeted Radiation Therapy Demonstrates High Complete Response Rate in Patients With Non-Hodgkin's Lymphoma

...adiation," said Richard A. Miller, M.D., president and chief executive officer of Pharmacyclics, and a co-author on the lymphoma study. Zevalin is a radiolabeled antibody approved for treatment of patients with relapsed non-Hodgkin's lymphoma. Zevalin binds to tumor cells and emits radiation to the tumor site. ...

Synvista Collaboration Demonstrates in Preclinical Studies the Mechanism for Defective Cholesterol Transport in Patients with Diabetes

...etabolizing agent, ALT- 2074, on functional reverse cholesterol transport. radiolabeled Hp2-2-Hb complexes injected into mice and rats with and without diabetes de...duals than Hp1-1 individuals. Reverse cholesterol transport, as measured by radiolabeled cholesterol efflux from pre-loaded macrophages, was significantly impaired ...

New Clinical Data for Cytogen's Quadramet and Prostacint to be Reported at Upcoming Major Medical Meetings

...pproved in the U.S. for the treatment of breast cancer in adjuvant and metastatic settings. The Company is also developing CYT-500, a third-generation radiolabeled antibody to treat prostate cancer. Cytogen's product-focused strategy focuses on attaining sustainable growth through clinical, commercial, and strate...

Cytogen Reports Publication Validating the Utility of its Proprietary ProChart Database

...pproved in the U.S. for the treatment of breast cancer in adjuvant and metastatic settings. The Company is also developing CYT-500, a third-generation radiolabeled antibody to treat prostate cancer. Cytogen's product-focused strategy centers on attaining sustainable growth through clinical, commercial, and strate...

Molecular Insight Pharmaceuticals, Inc. Presents Preclinical Data at Society Of Nuclear Medicine 2007 Annual Meeting

...tical candidate that targets angiotensin converting enzyme for the detection of heart failure and vascular inflammatory disease. Data on the company's radiolabeled small molecule molecular imaging pharmaceutical, MIP-1072, for the detection and staging of prostate cancer, were presented on June 3rd. -0- Abstrac...

New Data for Cytogen's QUADRAMET Reported at Annual ASCO Meeting

...pproved in the U.S. for the treatment of breast cancer in adjuvant and metastatic settings. The Company is also developing CYT-500, a third-generation radiolabeled antibody to treat prostate cancer. Cytogen's product-focused strategy centers on attaining sustainable growth through clinical, commercial, and strate...

Repeated Radioimmunotherapy With 131I-Labetuzumab Appears Safe and Effective in Colorectal Cancer with Liver Metastases

...University of Gottingen, Germany, and lead author of the study presented. "In 2008, we plan to initiate a multicenter, randomized trial evaluating the radiolabeled anti-CEA antibody at repeated doses of 40 - 50 mCi/m2," he commented further. In an early study, the German scientists reported a 5-year survival ra...
radiolabeled in Medical Dictionary

MIBG

... Iobenguane, also known as metaiodobenzylguanidine or mIBG , is a radiopharmaceutical. It is a radiolabeled molecule similar to norepinephrine. Metaiodobenzylguanidine ( MIBG ) is a substance that concentrates in neuroblastoma ... MIBG will be elimin...
radiolabeled in Biological News

CWRU receives $5 million from Ohio Third Frontier Commission

... Zhenghong Lee (UHCMC) and Jeremy Rich (CC) will collaborate to develop a method to non-invasively image cancer stem cells through the development of radiolabeled tracers. The CSCRM Administration, led by Debra Grega and Michael Gilkey, is responsible for coordinating, accounting and reporting on all of the...

UC Davis researchers find molecule that targets brain tumors

...o target brain cancer by implanting human glioblastoma cells both beneath the skin and in the brains of mice. The researchers injected the mice with a radiolabeled version of LXY1 and, using near-infrared fluorescence imaging, showed that the molecule did preferentially bind to human glioblastoma cells in both lo...

Researchers wake up viruses inside tumors to image and then destroy cancers

... the one produced by the herpes simplex virus, can be imaged by an injected radiolabeled chemical (FIAU), which can then be imaged using a gamma camera. "To p...inase it then produces to enable us to see the virus-associated tumors with radiolabeled FIAU." The researchers screened 2,700 agents until they hit upon Velca...

UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice

...BioSystems in Boston, seeks to solve this problem. The experimental system uses bioprobes created by wedding magnetized iron-oxide nanospheres to radiolabeled monoclonal antibodies. The bioprobes are cloaked in polymers and sugars that render them nearly invisible to the body's immune system. DeNardo an...

PET/MRI scans may help unravel mechanisms of prenatal drug damage

... in the striatum, where cocaine is known to bind to cell-surface receptors that result in a euphoric response," Benveniste said. The high uptake of radiolabeled cocaine in the placenta is also particularly relevant, the researchers said, because cocaine is known to constrict blood vessels in the placenta. It m...

Poplar trees redirect resources in response to simulated attack

...es, where it is quickly converted to sugar, and traced the movement of this radiolabeled sugar through the plants using autoradiography and other techniques. Autora...Brookhaven. Plants subjected to the jasmonic acid "attack" produced more radiolabeled sugar and delivered more of it to the roots than plants untreated with the ...
radiolabeled in Biological Technology

A simple method to sequence from bacterial colonies using [a-33P] radiolabeled ddNTPs and Thermo Sequenase

Introduction In traditional DNA sequencing systems, sequencing products are radioactively labeled using either endlabeled primers or by the incorporation of radiolabeled dNTPs during primer extension. Successful sequencing results produced by these two labeling methods are hi...

Peregrine Awarded European Patent for Innovative Labeling Technology Featured in New Study in The Journal of Nuclear Medicine

...Line labeling, was developed for the production of radiolabeled anti-cancer antibodies, but is applicable to other...ically reduce the complexity and cost of producing radiolabeled cancer drugs(1). In-Line labeling is already being used for the production of Peregrine's radiolabeled antibody Cotara(R), currently in Phase II trials f...

Pulmo BioTech Inc. Announces Paper to be Presented at Symposium

...l Symposium on Peptide Receptors and Kinin 2009 to be held in Quebec, Canada from June 26th to 29th. The paper, which is titled "Development of radiolabeled Adrenomedullin Analogs Designed for Molecular Imaging of the Pulmonary Circulation", will be part of the session "From a Peptide to a Drug: Rational D...

Covance Increases Early Clinical Footprint in Europe with Acquisition of Swiss-Based Early Clinical Development Site

...an 200 complex clinical trials since 2002, with roughly a third of them being first-in-human studies. The Basel site also has substantial expertise in radiolabeled and proof-of-concept studies, a wealth of experience in specialty therapeutic areas, and access to a large and active volunteer database. The bu...

Bradmer sponsors physician panel to raise awareness of brain cancer treatments

...://www.glassarttrial.com ) The Phase III GLASS-ART Trial derives its name from its description: GBM Locoregional Agent Survival Study - Antitenascin radiolabeled antibody Therapy Trial. The study is designed to determine the survival benefit derived from, and safety of, adding Neuradiab to the current standard ...

Cellectar, Inc. Begins GMP Production

...cal program and to continue the development of additional molecules." Cellectar's lead drug candidate, CLR1404, is a phospholipid ether (PLE) analog radiolabeled with iodine-131, a radioactive isotope commonly used to treat cancer. In pre-clinical evaluations, CLR1404 has shown the ability to carry the potent i...

Publication in Clinical Cancer Research Confirms Ability of Peregrine's Bavituximab to Target Tumor Blood Vessels with Excellent Specificity

...ats bearing prostate tumors, we expect that the observations will extend to other solid tumor types as well." In the study, researchers administered radiolabeled bavituximab to rats with prostate tumors and then conducted molecular imaging studies of the rats over the next several days. The results showed that ...

Counting Non-Aqueous Samples in the TopCount Microplate Scintillation and Luminescence Counter

...rases. Enzyme activity is often determined by measuring the conversion of a radiolabeled substrate to a product that can be separated from the substrate by chromato...are often done in microplates, and it is highly desirable to quantitate the radiolabeled product in this format, especially when the product can be eluted directly ...

Cell Proliferation Assays

...to evaluate the compatibility of donor and recipient tissues for organ transplants. Cell proliferation assays measure the incorporation of a radiolabeled DNA precursor, [ 3 H]-thymidine, into the replicating strands of DNA produced during cell division. Cultures are typically set up in 96-well microplat...

Use of FlashPlate Technology for In Vitro Measurement of 125I-Labeled TGF-1 Binding on Chimeric Extracellular Domain of Type II Transforming Growth Factor Receptor

...added to the well, gave a measure of the counting efficiency, which was evaluated at 5%. For the competition binding assay, the final concentration of radiolabeled ligand was 500 pM (specific activity 300-450 Ci/mmole), with final concentrations ranging from 0.05 to 200 nM for TGF-1, TGF-2 and TGF-3. B...
radiolabeled in Biological Products

Nitric Oxide Synthase Radiometric Assay Kit from Cayman Chemical

Description:... The NOS assay kit measures NOS activity by monitoring the conversion of radiolabeled arginine to citrulline. This assay is simple, sensitive, and specific for N... The kit includes sufficient materials and reagents for 50 total reactions. radiolabeled arginine and NADPH are not included with the kit....
Company:Cayman Chemical

LIGHTSHIFT EMSA Kit from Pierce Biotechnology, Inc.

Description:...ection equivalent to radioactive EMSA systems One day assay go from probe labeling to EMSA data analysis in a single day Stable probes unlike radiolabeled probes biotin labeled probes are stable for more than one year Biotin labeling kit sold separately customer can end-label DNA probes using the P...
Company:Pierce Biotechnology, Inc.

Ligase, T4 DNA from USB Corp.

Description:...contains 67mM Tris-HCl, (pH 7.8), 6.7mM MgCl 2 , 10mM DTT, 66M ATP and 3.3M radiolabeled pyrophosphate. Incubation is at 37C for 20 min. Note: ATP is an essential...ition: One Weiss unit is the amount of enzyme required to convert 1 nmol of radiolabeled phosphate from pyrophosphate into absorbable material in 20 min at 37C unde...
Company:USB Corp.

Porcine Neuromedin U-25 , 125I Conjugated/Tagged from PerkinElmer

Description:... Radiochemical Purity is >95%NEN radiolabeled Ligands\n\nReceptor-related research has long been enabled by the continual availability of new radiolabeled ligands selected to keep pace with new discoveries...you, scientist to scientist, to prepare the custom radiolabeled ligand that meets your specifications.\n\nWarning\...
Company:PerkinElmer

Porcine Neuromedin U-25 , 125I Conjugated/Tagged from PerkinElmer

Description:... Radiochemical Purity is >95%\nNEN radiolabeled Ligands\n\nReceptor-related research has long been enabled by the continual availability of new radiolabeled ligands selected to keep pace with new discoveries...you, scientist to scientist, to prepare the custom radiolabeled ligand that meets your specifications.\n\nWarning\...
Company:PerkinElmer

Porcine Galanin , 125I Conjugated/Tagged from PerkinElmer

Description:... Radiochemical Purity is >95%NEN radiolabeled Ligands\n\nReceptor-related research has long been enabled by the continual availability of new radiolabeled ligands selected to keep pace with new discoveries...you, scientist to scientist, to prepare the custom radiolabeled ligand that meets your specifications.\n\nWarning\...
Company:PerkinElmer

Human, Porcine Endothelin-1 , 125I Conjugated/Tagged from PerkinElmer

Description:... Radiochemical Purity is >95%NEN radiolabeled Ligands\n\nReceptor-related research has long been enabled by the continual availability of new radiolabeled ligands selected to keep pace with new discoveries...you, scientist to scientist, to prepare the custom radiolabeled ligand that meets your specifications.\n\nWarning\...
Company:PerkinElmer

Human, Porcine Endothelin-1 , 125I Conjugated/Tagged from PerkinElmer

Description:... Radiochemical Purity is >95%NEN radiolabeled Ligands\n\nReceptor-related research has long been enabled by the continual availability of new radiolabeled ligands selected to keep pace with new discoveries...you, scientist to scientist, to prepare the custom radiolabeled ligand that meets your specifications.\n\nWarning\...
Company:PerkinElmer

26S Proteasome Fraction Extract from GeneTex

Description:...oteasome PA28/11S REG complex, and ubiquitin ligase enzymes (E3s). GTX80880 is ideal for demonstrating ubiquitin proteasome degradation/conjugation of radiolabeled or immunodetectable substrates. Type: Proteins and peptides Form: 7.5 mg/ml in 25 mM HEPES, pH 7.6. ...
Company:GeneTex

Porcine Galanin , 125I Conjugated/Tagged from PerkinElmer

Description:... Radiochemical Purity is >95%NEN radiolabeled Ligands\n\nReceptor-related research has long been enabled by the continual availability of new radiolabeled ligands selected to keep pace with new discoveries...you, scientist to scientist, to prepare the custom radiolabeled ligand that meets your specifications.\n\nWarning\...
Company:PerkinElmer
radiolabeled in Biological Dictionary

Gene product

...e a common language to describe aspects of a gene product's biology. ... A major regulatory gene product is a cytosolic receptor to which radiolabeled 2, ... A Bacillus subtilis regulatory gene product for genetic competence and ... AB1761 Rabbit x Protein Gene Product 9.5 representative s...

DNA sequencing

..., how it's done, where ... What is DNA sequencing ? Whose genome was sequenced in the Human Genome Project? ... ... DNA polymerase-catalyzed radiolabeled two-step sequencing ... DNA sequencing : ... polyacrylamide gels for DNA sequencing , the appropriate amount ... DNA . Sequencing . 59. W...

DNA sequence

...f DNA -- enough copies to allow a machine ... Sequence for Yourself | Journey into DNA | Meet the Decoders ... ... DNA polymerase-catalyzed radiolabeled two-step sequencing ... DNA sequencing : ... polyacrylamide gels for DNA sequencing , the appropriate amount ... Dna Sequencing : Single...

DNA probes

...quirements. ... Lofstrand Labs has provided custom genomic/proteomic research services to ... GENOMIC DNA , SUBCLONING, MOLECULAR CLONING, OLIGOS, radiolabeled PROBES , ANTIGEN ... Information Staff, Agricultural Research Service, USDA. Communicating news and ... Boston Probes recently patented syntheti...
Other Tags
(Date:7/14/2014)... 2014 Summer is the best season of ... the beach, swimming and other outdoor adventures. The promotional product ... happy and healthy all summer long. The promo product gurus ... three must-have custom imprinted products everyone must have on hand ... course sunblock. Sunscreen helps protect skin from harmful ...
(Date:7/14/2014)... (PRWEB) July 14, 2014 Crystal Dental ... office in Sacramento. The announcement has been made via LAD ... In addition, the announcement has been made in order to ... services in the Sacramento area. , Crystal Dental offers a ... of the services offered by Crystal Dental include cosmetic dentistry ...
(Date:7/13/2014)... 2014 FORT LEE, N.J. – Authors ... approach to the science of tooth implants in ... This book describes recent advances and techniques in the world ... benefit people who have lost all of their natural teeth. ... first lower subperiosteal implant in 1940. It was a ...
(Date:7/13/2014)... 14, 2014 Recently, TopDresses100.com, a popular ... new range of multi-colored Quinceanera dresses to ... all of these colorful outfits are guaranteed to be ... up to 68% off. , TopDresses100.com has a wide ... and all its items are in stock and ready ...
(Date:7/13/2014)... 2014 Manchester United and AS Roma ... Guinness International Champions Cup. The 2014 ICC is one ... because of the talent of it brings in. Teams like ... will compete in the 2014 event spread across 10 American ... a game between Olympiacos and Milan and will conclude with ...
Breaking Medicine News(10 mins):Health News:Why These Three Summer Essentials from 4AllPromos Can Improve Summer 2Health News:Crystal Dental Announces the Opening of New Office Location in Sacramento 2Health News:Authors Leonard I. Linkow and Sheldon Winkler Feature Advancements in Implant Dentistry 2Health News:Authors Leonard I. Linkow and Sheldon Winkler Feature Advancements in Implant Dentistry 3Health News:Authors Leonard I. Linkow and Sheldon Winkler Feature Advancements in Implant Dentistry 4Health News:Cheap Multi-colored Quinceanera Dresses From TopDresses100.com 2Health News:Manchester United vs. AS Roma Tickets in Denver, CO at Sports Authority Field at Mile High: Ticket Down Slashes Ticket Prices on International Champions Cup in Denver 2Health News:Manchester United vs. AS Roma Tickets in Denver, CO at Sports Authority Field at Mile High: Ticket Down Slashes Ticket Prices on International Champions Cup in Denver 3
(Date:7/11/2014)... the Department of Energy,s Oak Ridge National Laboratory ... R&D Magazine in recognition of the year,s top ... tremendous value of our National Labs," said Secretary ... the National Labs continues to help our nation ... and technological innovations necessary to remain globally competitive." ...
(Date:7/11/2014)... The University of Chicago is creating a new ... at the University,s Institute for Molecular Engineering and ... million donation from the Millicent and Eugene Bell ... will reside within the Institute for Molecular Engineering. ... research project at the MBL,s Eugene Bell Center ...
(Date:7/11/2014)... The Chinese University of Hong Kong, BGI and other ... to salt tolerance, with implication for improving this important ... online in Nature Communications provides an effective ... , Soybean is an important crop for the world. ... less genetic diversities than their wild counterparts. Among the ...
Breaking Biology News(10 mins):ORNL wins eight R&D 100s 2ORNL wins eight R&D 100s 3ORNL wins eight R&D 100s 4New professorship in tissue engineering links molecular engineering, marine biology 2BGI reports a novel gene for salt tolerance found in wild soybean 2
Other Contents