Assembling the jigsaw puzzle of drug addiction
Using an integrative meta-analysis approach, researchers from the Center for Bioinformatics at Peking University in Beijing have assembled the most comprehensive gene atlas underlying drug addiction and identified five molecular pathways common to four different addictive drugs. This novel paper ...New piece found in colorectal cancer puzzle
Prostasin, a relatively unknown protease enzyme expressed in most epithelial cells, may play a role in the genesis of colorectal cancer. Researchers writing in the open access journal BMC Cancer have associated a reduction in the expression of inhibitors of the enzyme with malignant cellular beh...Piecing Together the HIV Prevention Puzzle
AVAC Report Assesses Progress in AIDS Vaccine, Microbicide and PrEP Research and Calls for Urgent Coordination and Leadership in Advance of Upcoming Results NEW YORK, May 18 /PRNewswire-USNewswire/ -- "It's an exciting time in HIV prevention research. We will see results from a number of cri...Scientists identify another piece of the weight-control puzzle
BOSTON Controlling body weight is a complicated process, as any frustrated dieter might attest. But as scientists continue to investigate the brain's intricate neurocircuitry and its role in maintaining energy balance, they are forming a clearer picture of the myriad events that lead to weight ga...Family History May Add to Alzheimer's Puzzle
Genes play only a part of underlying risk for dementia, study suggests TUESDAY, July 29 (HealthDay News) -- The gene most often associated with Alzheimer's disease doesn't provide a complete picture of overall risk, according to researchers who analyzed family histories of the disease....Pieces coming together in Parkinson's, cholesterol puzzle
CHAPEL HILL In 2006, University of North Carolina at Chapel Hill researchers published a study that found people with low levels of LDL cholesterol are more likely to have Parkinson's disease than people with high LDL levels. But that study could not answer the question of whether low LDL (low...Boffins a Step Closer to Solving Puzzle of Lou Gehrig's Disease
Moving closer to solving Lou Gehrig's disease mystery, UCLA, Italian chemists may have solved an important mystery about a protein that plays a key role in a particular form of amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, a progressive, fatal neuro-degenerative disorder...Depression - a Puzzle of Many Pieces
Medication in treating major depression is only one of many potential pieces in the puzzle according to a newly published UCLA study.// Published in the August 2006 edition of the American Journal of Psychiatry, the study used electroencephalogram (EEG) measurements to demonstrate an associat...Bush’s new prescription drug plan, a complex puzzle for the citizen
President Bush’s prescription drug plan came in to effect on Jan 1st, but the governors of many states like those of Pennsylvania, have trouble dealing with the issue//. The plan has been under study for more than a year but members of Medicare came to know about it when they received a booklet...MIT Biologists Solve Vitamin Puzzle
Solving a mystery that has puzzled scientists for decades, Massachusetts Institute of Technology (MIT) and Harvard researchers have discovered// the final piece of the synthesis pathway of vitamin B12--the only vitamin synthesized exclusively by microorganisms. B12, the most chemically comple...More Gene Mutations Linked to Autism Risk
...erited and New Genetic Mutations Acting Together-- PHILADELPHIA, June 26 /PRNewswire-USNewswire/ -- More pieces in the complex autism inheritance puzzle are emerging in the latest study from a research team including geneticists from The Children's Hospital of Philadelphia, the University of Pennsylva...Autism Studies Presented at Mid-Atlantic Research Consortium Meeting
...edging multifaceted research being pursued by the participating centers, using genetics, neurobiology and imaging studies to investigate the intricate puzzle of autism. "The last 20 years of research have made it clear that autism is not a single disease, but a continuum of multiple disorders -- that's...CSHL scientists harness logic of 'Sudoku' math puzzle to vastly enhance genome-sequencing capability
Cold Spring Harbor, N.Y. A math-based game that has taken the world by storm with its ability to delight and puzzle may now be poised to revolutionize the fast-changing world of genome sequencing and the field of medical genetics, suggests a new report by a team of scientists at Cold Spring Harbo...New piece found in the puzzle of epigenetics
This release is available in German . For many years scientists have known that the numerous biological functions of an organism are not regulated solely by the DNA sequence of its genes: Superordinate regulatory mechanisms exist that contribute to determining the fate of genes. Although ...Fossils and layers: Solving the terrane puzzle of the North American cordillera
Boulder, CO, USA Tectonostratigraphic terranes comprise a huge portion of real estate in western North America. Terranes are regional, discrete, fault-bound blocks containing rocks and fossils very different from those in adjacent terranes. When mapped, terranes resemble a collage of mixed rocks,...Researchers uncover new piece to the puzzle of human height
In studies involving more than 35,000 people and a survey across the entire human genome, an international team supported in part by the National Institutes of Health (NIH) has found evidence that common genetic variants recently linked to osteoarthritis may also play a minor role in human height....Aerosol: A key piece of the climate change puzzle
Fitting all the different pieces of the climate change puzzle together is one of the major challenges of our age. Aerosol is a key piece of this puzzle, but the size and shape of its effect is still unclear a fact that jeopardises the reliability of all current predictions of climate change. ...New step forward in search for solution to infection puzzle
Scientists at the University of York have helped to reveal more about the way bacteria can attach to human tissues. The study could help in the development of new treatments for serious heart conditions such as infective endocarditis. The researchers studied the way a protein found on the ...Chloroform provides clue to 150 year old medical puzzle
One of the earliest general anaesthetics to be used by the medical profession, chloroform, has shed light on a mystery thats puzzled doctors for more than 150 years how such anaesthetics actually work. A discovery described as true serendipity made by Leeds University PhD student Dr Yahya Bahn...UC San Diego physicists tackle knotty puzzle
Electrical cables, garden hoses and strands of holiday lights seem to get themselves hopelessly tangled with no help at all. Now research initiated by an undergraduate student at the University of California, San Diego has resulted in the first model of how knots form. The study, published thi...Prehistoric aesthetics explains snail biogeography puzzle
ANN ARBOR, Mich.---The answer to a mystery that long has puzzled biologists may lie in prehistoric Polynesians' penchant for pretty white shells, a research team headed by University of Michigan mollusk expert Diarmaid Foighil has found. The team's findings, published online Sept. 12 in the B...Major link in brain-obesity puzzle found
A single protein in brain cells may act as a linchpin in the body’s weight-regulating system, playing a key role in the flurry of signals that govern fat storage, sugar use, energy balance and weight, University of Michigan Medical School researchers report. And although it’s far too early to sa...New clues about a hydrogen fuel catalyst
...oratory on the PNNL campus. The data from the various experiments were like puzzle pieces that the team had to fit together. To put the puzzle together, the team used computer models to construct a theoretical molecula...Scientists engineer superconducting thin films
...rent combinations of non-superconducting materials. "Further study of the temperature-enhancement mechanism might even tell us something about the big puzzle the mechanism underlying high-temperature superconductivity, which remains one of the most important open problems in condensed matter physics," he s...International team of scientists discover clue to delay of life on Earth
...r of biogeochemistry at UCR who is a long-time collaborator of Anbars and also an author of the paper. Clints data are an important new piece in a puzzle weve been trying to solve for many years, says Anbar. Tim and I have suspected for a while that if the oceans at that time were oxygen deficient they ...DOE JGI plumbs termite guts to yield novel enzymes for better biofuel production
...out the identities of the microbial players in the mixture and the metabolic profile of the enzymes that they produce. From this reconstructed liquid puzzle emerged the identities of a dozen different phyla -- broad groupings of microbial life forms. "Our analysis revealed that the hindgut is dominated b...Massive reanalysis of genome data solves case of the lethal genes
...onstructed in one pass, said Rubin. You always get gaps in the assembly. This is annoying, expensive, and compels us to close the gaps and finish the puzzle so that we could tell the story behind the sequence. Our breakthrough was in understanding that gaps occur because some genes cannot be transferred t...Broadband freedom mandatory for growth
...it, Wisconsin can position itself to be on a competitive footing as we compete for higher paying jobs around the world. An important piece of the puzzle is missing, however. I have authored 2003 Senate Bill 302 (SB 302), which would change the way the state views broadband services. My bill would cha...Wisconsin Angel Network is part of states focus on entrepreneurship
...aukee, TechStar represents the efforts of five academic institutions to invest in that regions high-growth economy. Last week, another piece of the puzzle fell into place when Doyle announced the creation of the Wisconsin Angel Network. Flanked by Department of Financial Institutions Secretary Lorrie Kea...OpGen completes $5 million investment round
...g or extra DNA , he said, while most existing methods focus on differences in analogous genes between organisms. That could make it a piece of the puzzle that is personalized medicine, helping choose medicines that are more appropriate for different people based on their genes. OpGens tests could hav...