Research Reveals How Down Syndrome Shields Against Cancer

... the departments of oncology and pediatrics at Georgetown University's Lombardi Cancer Center in Washington, D.C. Take the example of Avastin, the prototypical anti-angiogenesis drug. "It's only showing a marginal benefit, and it has side effects," Toretsky said. As for this contribution to the angiogenesi...

GEN Reports on Strategies to Overcome Blood-Brain Barrier

... cross the BBB, researchers modify their chemical structures so that they resemble nutrients that are transported across the BBB by specific SLCs. The prototypical drug that uses this strategy (which was developed long before mechanisms of CMT were known) is L-DOPA, the major current drug for Parkinson's disease....

JCI online early table of contents: Feb. 7, 2008

... EDITOR'S PICK: VEGF-B helps nerve cells cheat death without unwanted side effects The prototypical member of the VEGF family of proteins, VEGF, has recently been shown to protect cells in the nervous system from death and degeneration. However, its ...

Signalife to Deploy Fidelity 100 Heart Monitors for AFL

...will be present when AFL conducts its screening programs in various communities. AFL anticipates that it will conduct many of these programs using its prototypical moving "medical center truck". AFL has indicated that additional health care testing and screening will be provided in these centers. This screening p...

Effects of Multiple Copies of Genes on Disease Risk

... Jackson Laboratory in Bar Harbor, Maine. For their analysis, researchers compared the genome of each of the 20 mouse strains against that of the prototypical research mouse strain, C57BL/6J. "That's the 'plain vanilla' mouse genome," Graubert explains. "Just like the reference human genome sequence tha...

Pharmaceutical Companies Banned from Giving Gifts at Stanford

...inman, a University of California, San Francisco. He said ‘Even though it's subtle, it can influence decisions.’ Steinman added, "Lunch is the prototypical freebie." Free meals at seminars, while seemingly insignificant, have become important to many time- and cash-deprived residents and medical stud...

prototypical in Medical Dictionary

Potassium hydroxide

... Potassium hydroxide is the inorganic compound with the formula KOH. Along with sodium hydroxide , this colourless solid is a prototypical "strong base". It has many industrial and niche applications. Most applications exploit its reactivity toward acids and its corrosive... ...

prototypical in Biological News

GEN reports on strategies to overcome blood-brain barrier

... cross the BBB, researchers modify their chemical structures so that they resemble nutrients that are transported across the BBB by specific SLCs. The prototypical drug that uses this strategy (which was developed long before mechanisms of CMT were known) is L-DOPA, the major current drug for Parkinson's disease....

UCLA researchers solve decade-old mystery

...gure out the rest, said Hakan Gunaydin, a UCLA graduate student in Ozolins lab and another one of the studys authors. Sodium alanate in itself is a prototypical complex hydride with a reasonable storage density and very good kinetics. Hydrogen goes in and comes out quickly but it wouldnt be practical for a car...

Scientists decipher mechanism behind antimicrobial 'hole punchers'

...hered the molecular mechanism behind selective antimicrobial activity for a prototypical class of synthetic compounds. The compounds, which mimic antimicrobial pep...University of Massachusetts at Amherst, the researchers first synthesized a prototypical class of antimicrobial compounds, then used synchrotron small-angle X-ray s...

Beauty and the brain

...quickly." The research follows up on earlier studies establishing that prototypical images are rated as more beautiful or appealing than variations of the same...lator of mate value or any other 'programmed-brain' argument to explain why prototypical images are more attractive," Winkielman said. "The mental mechanism appears...

prototypical in Biological Technology

Measuring what works and what doesn't in the prototypical school

If you're looking for an ambitious mission statement, consider this pledge from the bipartisan Wisconsin School Finance Adequacy Initiative: "We will not simply propose adding new dollars on top of current dollars, but propose a complete new reuse of all dollars first those currently in the (K-1...

Domain walls that conduct electricity

...tremely sensitive to their environment, says Ramesh. "Materials called multiferroics are an example of this kind of material, and bismuth ferrite is a prototypical multiferroic." The promise of multiferroics Multiferroics may be an unfamiliar term, but is not likely to remain so for long. It describes ma...

Controlling the size of nanoclusters: First step in making new catalysts

...ery stable or "magic" cluster of four atoms of molybdenum and six atoms of sulfur deposited on a gold surface. This small nanocluster is thought to be prototypical of active catalyst particles because all the molybdenum metal atoms are exposed and therefore can react with other molecules. Exploring larger and mor...

Attagene's Breakthrough Transcription Factor Profiling Technology to be Described in Nature Methods

...onmental toxicants. This application has been validated as a part of the ToxCast program of the U.S. Environmental Protection Agency. Currently, the prototypical FACTORIAL(TM) evaluates slightly more than 40 transcription factor families, but the system can be readily expanded by including additional reporters....

Readers react to 'Cingular confusion'

...ls you two things: (1) that I don't pay close attention to my finances, and (2) that Cingular has so confused its customers (of which I believe I am a prototypical example) that customers are paying or not paying a bevy of bills hoping to find some sort of normal rhythm to their mobile phone expenses. In the past...

prototypical in Biological Definition

Synapse

...es 3 Synaptic strength 4 Integration of synaptic inputs 5 Detailed properties and regulation 6 References Anatomy At a prototypical synapse, such as a dendritic spine , a mushroom-shaped bud projects from each of two cells and the caps of these buds press flat against one another...