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Proteins in Medical News

Brain Imaging (MRI/PET) and Measurements of Proteins in Spinal Fluid May Improve Alzheimer's Prediction and Diagnosis

VIENNA, Austria, July 14 /PRNewswire-USNewswire/ -- Changes in the brain measured with MRI and PET scans, combined with memory tests and detection of risk proteins in body fluids, may lead to earlier and more accurate diagnosis of Alzheimer's, according to new research reported toda...

Researchers identify key proteins needed for ovulation

Researchers from the National Institutes of Health and other institutions have identified in mice two proteins essential for ovulation to take place. The finding has implications for treating infertility resulting from a failure of ovulation to occur as well as for developing new means to prev...

Scripps research scientists model 3D structures of proteins that control human clock

In an Early Edition issue of The Proceedings of the National Academy of Sciences ( PNAS ) on April 9, 2009, the researchers report that they have been able to determine the molecular structure of a plant photolyase protein that is surprisingly similar to two cryptochrome proteins that control th...

Motor proteins may be vehicles for drug delivery

Specialized motor proteins that transport cargo within cells could be turned into nanoscale machines for drug delivery, according to bioengineers. Chemical alteration of the proteins' function could also help inhibit the growth of cancerous tumors. Each cell in the body contains motor proteins ...

Important new model shows how proteins find the right DNA sequences

Researchers at Uppsala University and Harvard University have collaboratively developed a new theoretical model to explain how proteins can rapidly find specific DNA sequences, even though there are many obstacles in the way on the chromosomes. The findings are being published today in the scient...

Stem Cell Innovations' C3A Human Liver Cell Line is Capable of Producing Biosimilar Serum Proteins for Follow-On Biologics

Blood clotting proteins factor 8 and 9 are first target indications HOUSTON, Feb. 24 /PRNewswire-FirstCall/ -- Stem Cell Innovations' (Pink Sheets: SCLL) liver assist device program has additional application in the production of biosimilar and novel proteins. "Many of the commercially impor...

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Proteins in Medical Technology

Fruitfly Model of a Neuropathic Disease Demonstrates Novel Role for Proteins in the Family of aTyr Pharma's Product Class

SAN DIEGO, July 13 /PRNewswire/ -- Research published in the June 26, 2009 edition of Proceedings of National Academy of Sciences provides further evidence for novel roles of tRNA synthetases in disease, validating the therapeutic potential for aTyr Pharma's new class of naturally occurring prot...

Aiming at Multiple Alzheimer's Proteins May be Key to Success

CLARKSBURG, Md., Oct. 21 /PRNewswire/ -- An independent team of scientists is leading Alzheimer's disease research in a new, promising direction. Through a $1 million grant they received last year from Alzheimer's Disease Research, a program of the American Health Assistance Foundation (AHAF),...

Pressure Cycling Technology (PCT) Results in a Higher Yield of Proteins and in the Extraction of Proteins Not Previously Identified in Cancer, Stroke, and IVF Studies

SOUTH EASTON, Mass., July 1 /PRNewswire-FirstCall/ -- Pressure BioSciences, Inc. (Nasdaq: PBIO ) ("PBI") today announced that scientists from the New York University ("NYU") School of Medicine and the Brooklyn Hospital Center presented results yesterday on advances they made in the areas of b...

Adlyfe Study on the Detection of Misfolded Proteins Published in the Journal Transfusion

Misfolded Protein Diagnostic (MPD) Shown to be Sensitive and Specific Technology Applicable for the Detection of a Host of Amyloid Neurological Diseases including Creutzfeldt-Jakob Disease (CJD), Alzheimer's, and Parkinson Disease ROCKVILLE, Md., Aug. 29 /PRNewswir...

St. Jude Study Gives New Insights Into How Cells Accessorize Their Proteins

Researchers have determined how an enzyme that stitches all-important molecular adjustments onto proteins contorts itself to regulate its own function MEMPHIS, Tenn., Sept. 18 /PRNewswire-USNewswire/ -- St. Jude Children's Research Hospital investigators have gained new insight into how the ...

Data Presented at AACR Meeting Shows Peregrine's Immunocytokine Fusion Proteins Reduce Growth of B-Cell Lymphoma Tumors by 85% in Preclinical Studies

- New Studies Confirm That Fusion Proteins Made by Combining Cytokines With Peregrine's Anti-PS Antibodies Demonstrate Increased Anti-Tumor Activity With No Observable Toxicity - LOS ANGELES and TUSTIN, Calif., April 18, 2007 /PRNewswire-FirstCall/ -- Peregrine Pharmaceuticals, Inc. , a clinical s...
Proteins in Medical Products

BD Cell-Tak™ Cell and Tissue Adhesive

Description:...BD Cell-Tak™ Cell and Tissue Adhesive is a formulation of polyphenolic proteins extracted from Mytilus edulis (marine mussel). These proteins are the key components of the glue secreted by the mussel to anchor itself ...
Company:BD Diagnostic Systems

120 Mini-Vertical Gel System

Description:... The 120 Mini-Vertical Gel System simplifies the process of separating proteins and nucleic acids in a mini-PAGE format. It is able to run four gels at a time, maximizing throughput and utility. To maximize utility and throughput...
Company:ThermoFisher Scientific

E-PAGE™ 96 High-Throughput Protein Electrophoresis System

Description:... The E-PAGE™ 96 High-throughput protein electrophoresis system is an ideal tool for high-throughput screening of proteins via western blotting or in gel staining. The system consists of self-contained pre-cast gels that include a buffered gel matrix and electrodes package...
Company:Invitrogen

Free Activin AB ELISA Test

Description:... a variety of other tissues (2). In addition to their endocrine role, these proteins have been shown to affect the growth and differentiation of a number of cel..., and hematopoietic progenitor and erythroleukemia cells (2). Two binding proteins have been described for the Activins and Inhibins: Follistatin and a-2 macr...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin A ELISA Test

Description:... a variety of other tissues (2). In addition to their endocrine role, these proteins have been shown to affect the growth and differentiation of a number of cel..., and hematopoietic progenitor and erythroleukemia cells (2). Two binding proteins have been described for the Activins and Inhibins: Follistatin and a-2 macr...
Company:Diagnostic Systems Laboratories, Inc.

Free Activin B ELISA Test

Description:... a variety of other tissues (2). In addition to their endocrine role, these proteins have been shown to affect the growth and differentiation of a number of cel..., and hematopoietic progenitor and erythroleukemia cells (2). Two binding proteins have been described for the Activins and Inhibins: Follistatin and a-2 macr...
Company:Diagnostic Systems Laboratories, Inc.

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Proteins in Medical Dictionary

Vitamin K

... K is an essential nutrient that is needed by the liver in order to form proteins that promote blood clotting and prevent abnormal bleeding. Non-profit...sively. ... Without vitamin K , the carboxylation does not occur and the proteins that are ... are not the first time that vitamin K safety has b...

Vesicle

...flux of calcium caused by the ... But sure, I gave credit to the synaptic proteins as doing the " vesicle management" work. ... MySpace Music profile for...ive zone, vesicle and plasma membrane proteins, with the ... Possible proteins on the vesicle membrane and pre-synaptic membrane that act as ... ...

Tuberculin

...sis (TB) ... Have had a positive tuberculin skin test in the past. Have had TB in the past. ... tuberculin n. A sterile liquid containing proteins extracted from cultures of tubercle bacilli and used in tests for tuberculosis Mantoux test n. A tuberculin test in which a small amount of t...

Tryptophan

...discuss tryptophan supplement optimal use. ... tryptophan ( ) also tryptophane ( ) n. An essential amino acid, C 11 H 12 N 2 O 2 , formed from proteins during digestion by the action of proteolytic Explains how tryptophan , which is found in turkey, can affect the body but suggests that heavy m...

Transfusion reaction

...ulation may be the only sign of a hemolytic transfusion reaction ... Transfusion reaction An allergic reaction to some of the cells or proteins in another person's ... Febrile non-hemolytic transfusion reaction ... ... goal of treatment is to prevent or treat severe effects of trans...

Toxins

... Toxins can be small molecules, peptides, or proteins that are capable of causing ... Toxins vary greatly in their severity, ranging from usually minor and acute (as ... toxin n. A poisonous s...
Proteins in Biological News

Targeting helpers of heat shock proteins could help treat cancer, cardiovascular disease

AUGUSTA, Ga. Dissecting how heat shock protein 90 gets steroid receptors into shape to use hormones like estrogen and testosterone could lead to targeted therapies for hormone-driven cancers, such as breast and prostate, that need them as well, Medical College of Georgia researchers say. "We ...

TRAPping proteins that work together inside living cells

RICHLAND, Wash. -- DNA might be the blueprint for living things, but proteins are the builders. Researchers trying to understand how and which proteins work together have developed a new crosslinking tool that is small and unobtrusive enough to use in live cells. Using the new tool, the scientists...

Pliable proteins keep photosynthesis on the light path

Photosynthesis is a remarkable biological process that supports life on earth. Plants and photosynthetic microbes do so by harvesting light to produce their food, and in the process, also provide vital oxygen for animals and people. Now, a large, international collaboration between Arizona State...

Autopilot guides proteins in brain

Proteins go everywhere in the cell and do all sorts of work, but a fundamental question has eluded biologists: How do the proteins know where to go? "There's no little man sitting there, putting the protein in the right place," said Don Arnold, molecular and computational biologist at the USC C...

New high-throughput screening technique makes probing puzzling proteins possible

Understanding the tens of thousands of proteins that compose the human proteome has emerged as a key challenge of this century, and research efforts to date have already enabled major advances in drug discovery and understanding basic biology. But many potential avenues have been blocked by lack o...

Scripps research scientists 'watch' as individual alpha-synuclein proteins change shape

In an Early Edition publication of The Proceedings of the National Academy of Sciences ( PNAS ) this week, the researchers demonstrate the "alpha-synuclein dance" the switching back and forth of the protein between a bent helix and an extended helix as the surface that it is binding to changes....

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Proteins in Biological Technology

Assay Designs(TM), Inc. Announces Release of First Available Product for Multiplex Analysis of Heat Shock Proteins

ANN ARBOR, Mich., June 1 /PRNewswire/ -- Assay Designs, Inc., a leading provider of immunoassay kits, antibodies, and reagents to the life science and translational research markets, has announced the release of the first commercially available multiplex assay dedicated to the analysis of heat sho...

Intrinsic Bioprobes, Inc. Enters into a $1.27M Contract with the National Cancer Institute to Develop Multiplex Mass Spectrometric Immunoassays for Detection of Low Abundance Cancer-Related Proteins

TEMPE, Ariz., March 31 /PRNewswire/ -- Intrinsic Bioprobes, Inc. today announced the start of a contract with the National Cancer Institute to develop effective technologies for accurate measurement of cancer-related proteins and peptides that improve diagnostic capabilities by effectively discern...

DSM and Crucell Sign Agreement with Bioceros to Serve as Pre-Approved Cell Line Generation Partner of PER.C6(R) Cell Line Proteins

LEIDEN, The Netherlands, and PARSIPPANY, N.J., Feb. 10 /PRNewswire/ -- DSM Biologics and Crucell N.V. (Euronext, Nasdaq: CRXL ; Swiss Exchange: CRX) announced today that they have entered into an agreement with Bioceros B.V. of Utrecht, The Netherlands to join their Vendor Network. Under the ter...

Scientists use light to control proteins

A team of researchers from Penn State and the University of Texas Southwestern Medical Center has discovered a way to use light to control certain proteins that catalyze biochemical reactions. "This is one of the first examples of someone successfully controlling the activity of a protein using l...

measurement of green fluorescent proteins and a red fluorescent protein in live cells in the Analyst GT multimode reader

Evelyn McGown, Ph.D., Jinfang Liao, M.D., Ph.D., Mary Kassinos, Irina Osetinsky and Jayne Hesley, Molecular Devices Corporation, 1311 Orleans Dr., Sunnyvale, CA 94089. Introduction Fluorescent proteins have become enormously popular as tools for monitori...

Detection and quantitation of low-abundant proteins with ECL Plex fluorescent Western blotting

O. Rönn 1 , M. Landström 2 , A. Edman-Örlefors 1 , and S. Edlund 1 1 GE Healthcare, Uppsala, Sweden 2 Ludwig Institute for Cancer Research, Uppsala, Sweden ECL Plex™ Western Blotting Detection System ...

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Proteins in Biological Products

Rabbit Anti-M13 Bacteriophage Coat Proteins Polyclonal Antibody, Unconjugated from Abcam

Description: Rabbit polyclonal to M13 Bacteriophage Coat Proteins ( Abpromise for all tested applications)....
Company:Abcam

SH3 Proteins II Sampler Kit from BD Biosciences Pharmingen

Description: SH3 Proteins II Sampler Kit 10g each...
Company:BD Biosciences Pharmingen

Bulk Enzymes/Bulk Proteins from Molecular Biology Resources

Description: Molecular Biological Resources offers bulk quantities of existing protein products. Please see the Chimerx divisions website for existing products and contact lloconne@molbiores.com for pricing....
Company:Molecular Biology Resources

Essential Techniques: Gel Electrophoresis: Proteins from Promega

Description: Edited by D.M. Gersten (1996) Provides comprehensive descriptions of the techniques available for analytical gel electrophoresis of proteins and offers clear step-by-step protocols for all of the most important procedures....
Company:Promega

mitochondrial proteins (human heart) for SDS-polyacrylamide gel electrophoresis from Molecular Probes (Invitrogen)

Description: mitochondrial proteins (human heart) for SDS-polyacrylamide gel electrophoresis *2 mg/mL*...
Company:Molecular Probes (Invitrogen)

mitochondrial proteins (human heart) for 2-D gel electrophoresis from Molecular Probes (Invitrogen)

Description: mitochondrial proteins (human heart) for 2-D gel electrophoresis *5 mg/mL*...
Company:Molecular Probes (Invitrogen)

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Proteins in Biological Definition

Actin

...nt component in filament production is the Arp2/3 proteins , which serve as sites for nucleation, stimulating...e formation of G-actin trimers. All of these three proteins are regulated by cell signaling mechanism. O...of structures: bundles and networks. Actin-binding proteins dictate the formation of either structure since t...

Adenosine triphosphate

...ds is carried out. This energy can be used by a variety of enzymes , motor proteins , and transport proteins to carry out the work of the cell. Also, the hydrolysis yields free inorga...

Affinity chromatography

...chromatography is for the purification of recombinant proteins. Essentially proteins are tagged with a known affinity ligand in order to aid their purificatio...for affinity binding (if the molecule is a protein these are called fusion proteins ). Such tags include six His tags (six Histidine residues added to one or...

Albumin

... normal range of albumin concentrations in human blood is 3.5 to 5.0 g/dL, and albumin normally constitutes about 60% of plasma protein; all other proteins present in blood plasma are referred to collectively as globulin . Albumin is essential for maintaining the oncotic pressure needed for proper dist...

Alpha helix

... In proteins , the α helix is a major structural motif in secondary structure . It was first postulated by Linus Pauling , Robert Corey , and Herman Bran...

Alternative splicing

...s done by Serine/Arginine-residue proteins, or SR proteins . The use of alternative splicing factors leads to...tion can be stored much more economically. Several proteins can be encoded in a DNA sequence whose length would only be enough for two proteins in the prokaryote way of coding. Others have not...
Proteins in Biological Dictionary

Proteins

Proteins are organic compounds made of amino acids arranged in a linear chain. The amino acids in a polymer chain are joined together by the peptide bonds between the carboxyl and amino groups of adjacent amino acid residues.... protein n. Any of a group of complex organic macromole...

Transmembrane proteins

A transmembrane protein is a protein that spans the entire biological membrane. Transmembrane proteins aggregate and precipitate in water. They require detergents or nonpolar solvents for extraction, although some of them... Membrane or Transmembrane receptors are specialized integral ...

Chaperone Proteins

In molecular biology, chaperones are proteins that assist the non-covalent folding disassembly of other macromolecular structures, but do not occur in these structures when the latter are performing their normal biological... Chaperone ( protein ), a protein that assists the non-covale...

Zinc finger

...lecting zinc finger protein (ZFP) target sites and for designing the proteins that will target them. ... The Zinc Finger Consortium (www.zincfing... and Straightforward Guide: What Is a Zinc Finger ? ... Zinc finger proteins often bind to DNA and RNA because their shape allows close ... Finding ...

Xanthophyll

...LAR DEGENERATION. The high levels of the xanthophylls in the macula may indicate a protective role ... Analysis of the xanthophyll binding LHC proteins showed that the Lhcb5 ... from the IEF gel showed differences in xanthophyll composition: ... ...

Western blotting

...r A confirmatory test for HIV exposure that identifies antibodies to HIV proteins and ... The western blot (alternatively, protein immunoblot) ... ...mobilization on the ... Western blotting ": electrophoretic transfer of proteins from sodium dodecyl ... A Western blot is a method in molecular bi...
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