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proliferate in Medical News

Transplanted liver cells function in older animals but do not proliferate as much as in younger ones

When things go right, transplanted healthy liver cells transplanted by infusion or injection will find their way to the liver, integrate into the damaged tissue, start proliferating, and take over the liver's work of helping with digestion and removing waste products and worn-out cells from the bl...

Menin Gene Mutation made Insulin Secreting Cells to Proliferate

Acute loss of a protein named menin – involved in tumor-suppression or cell-proliferation-suppressing function resulted in the proliferation of pancreatic islet cells, which again affected blood sugar// regulation - researchers at the University of Pennsylvania School of Medicine reports. In hu...

Cryo-Cell to Present Novel Adult Stem Cell Research During 2009 China Medical Biotech Forum

...rual blood (known as MenSCs) during the Fourth China Medical Biotech Forum, August 8-10 in Dalian, China. Data from an in vitro study show that MenSCs proliferate rapidly and have significant potential to develop into multiple cell types. Dr. Julie Allickson, Vice President of Laboratory Operations and Research ...

Bcl6 gene sculpts helper T cell to boost antibody production

...s, where they play a helper T cell's traditional role in B cell proliferation and antibody development. "In germinal centers, the B cells not only proliferate but they also undergo hypermutation in their immunoglobulin genes so they can produce a diverse class of antibodies," Dong said. "These mutations also...

Study in this Week's Issue of Cell Finds Injected Growth Factor Spurs Heart Regeneration

...ts have focused on stem-cell based strategies, our work suggests that stem cells aren't required and that stimulating differentiated cardiomyocytes to proliferate may be a viable alternative," says Kühn, the study's senior investigator and a practicing pediatric cardiologist at Children's since 2007. ...

Injection May Heal Damaged Heart

...em cell-based strategies, our work suggests that stem cells aren't required and that stimulating differentiated cardiomyocytes [heart-muscle cells] to proliferate may be a viable alternative," Kuhn, the study's senior investigator, said in a news release from the hospital. More information The American...

Parent's Guide to Cord Blood Foundation Introduces New Brochure During Cord Blood Awareness Month to Address Critical Education Gap

...te more versatility and flexibility when used in transplantation. In addition, cord blood stem cells have demonstrated embryonic-like capabilities to proliferate and develop into all of the major cell types in the body. For more than 20 years, cord blood stem cells have been used in transplants to cure patient...

Newly appreciated membrane estrogen receptor important therapeutic target for breast cancer

...ent." In general, about two-thirds of all breast cancer cases involve tumors that retain expression of estrogen receptors (ER). They are presumed to proliferate in response to estrogen produced by the patient. Consequently, patients with ER-positive tumors receive hormonal agents (known as ER antagonists) that...

Study identifies biomarker that safely monitors tumor response to new brain cancer treatment

...very initial signals for the T cells to mount an anti-tumor immune attack. Without the surveillance of dendritic cells, brain tumors go undetected and proliferate rapidly. In the technique devised by Castro and Lowenstein, one of the proteins (the immune stimulatory cytokine Flt3L) attracts dendritic cells f...

SailPoint and Cyber-Ark Partner to Prevent Insider Threats

...unts. (Logo: http://www.newscom.com/cgi-bin/prnh/20090218/SAILPOINTLOGO ) Privileged accounts, such as UNIX Root or Windows Administrator, proliferate through an organization's infrastructure on every server, device, application, database, desktop and laptop. While necessary for the administration of...
proliferate in Medical Technology

Injection Reverses Heart-Attack Damage

...ts have focused on stem-cell based strategies, our work suggests that stem cells aren't required and that stimulating differentiated cardiomyocytes to proliferate may be a viable alternative," says Kuhn, the study's senior investigator and a practicing pediatric cardiologist at Children's since 2007. Wh...

Gene Marker May Improve Odds of Stem Cell Therapies for Disease

...ells must be cultivated in vitro. During this process, MSCs are often compromised when they enter senescence, or aging, which limits their capacity to proliferate and differentiate into new tissues, making them useless for treatment. In the current study, researchers studied senescent MSCs drawn from rats i...

Parasites That Live Inside Cells Use Loophole to Thwart Immune System

...zymes and poisoning them with nitric oxide. However, some pathogens, such as those that cause tuberculosis and toxoplasmosis, have evolved to live and proliferate within macrophages themselves. To do so, these intracellular pathogens deploy an arsenal of weapons to avoid and counterattack macrophage's own weapon...

St. Jude Study Shows How T Cell's Machinery Dials Down Autoimmunity

...nction of T cell receptors, proteins that span the cell membrane of T cells. These receptors receive outside signals that instruct T cells to develop, proliferate and transmit those signals into the cell. The St. Jude investigators sought to understand why T cell receptors need many copies of switch-like compone...

Basic Science Discoveries Yield Progress in Hepatology

...nsive liver tissue formation/replacement has not yet been achieved with either adult or embryonic stem cells). Immortalized hepatocytes could engraft, proliferate and correct a disease phenotype of a recipient liver, but safety issues (e.g. tumor formation) still remain a concern. To date, in the laboratory, ste...
proliferate in Medical Definition

Thymocyte

...to be important for thymus entry include CD44 , P-selectin (CD62P), and the chemokine receptor CCR9. [3] Following thymus entry, progenitors proliferate to generate the ETP population. This step is following by the generation of DN2 thymocytes which migrate from the cortico-medullary junction toward th...
proliferate in Medical Dictionary

In situ

...noma in situ (CIS) is an early form of carcinoma defined by the absence of invasion of surrounding tissues. In other words, the neoplastic cells proliferate in their normal habitat, hence the name ' in situ ' . For... In Situ Flushing Action Team includes ... In situ flushing technolo...
proliferate in Biological News

Stem cell 'daughters' lead to breast cancer

..., luminal progenitor cells multiply rapidly in the presence of certain growth factors. In BRCA1 women these cells don't even require growth factors to proliferate they misbehave from the outset. "We also know that the BRCA1 gene is required for normal DNA repair. There may therefore be a triple whammy effect...

Nanodiamonds deliver insulin for wound healing

...he nanodiamond clusters over a period of several days. Insulin accelerates wound healing by acting as a growth hormone. It encourages skin cells to proliferate and divide, restores blood flow to the wound, suppresses inflammation and fights infection. Earlier investigations have confirmed an increase in alkal...

Protein that promotes cancer cell growth identified

...ed by Kristiina Vuori, M.D., Ph.D., professor and director of the Cancer Center at Burnham, showed that Caspase-8 caused neuroblastoma cancer cells to proliferate and migrate. For the first time, Caspase-8 was shown to play a key role in relaying the growth signals from epidermal growth factor (EGF) that cause c...

C. difficile spores spread superbug

... the microbial ecosystem was disrupted. Because C. difficile is resistant to many antibiotics, the bacterium was able to exploit the opportunity and proliferate where other gut bacteria had succumbed to the antibiotics. This allowed the C. difficile to flourish and dominate the microbiota of the mouse. Al...

When cells reach out and touch

...ancerous cells growing in a dish stop multiplying when they touch each other. Cancer cells, on the other hand, lose contact inhibition and continue to proliferate even when they're touching. The researchers suspected that microRNAs might play a role in contact inhibition because whenever they studied these enigm...

Scientists shed light on inner workings of human embryonic stem cells

...science Research Institute. "The beauty and elegance of stem cells is that they have these dual properties," said Kosik. "On the one hand, they can proliferate they can divide and renew. On the other hand, they can also transform themselves into any tissue in the body, any type of cell in the body." The r...

Scientists identify key gene that protects against leukemia

...ell types -- a discovery that could eventually open the door to more streamlined treatments for leukemia and other blood cancers, in which blood cells proliferate out of control. Additionally, in investigating the mechanisms of this gene, the scientists uncovered evidence that could lead to a protocol for bo...

Time (and PPAR-beta/delta) heals all wounds

...nt maintenance, but how do skin cells know when to proliferate and at what rate? In the March 23, 2009 issue of t...948; to make sure overlying epithelial cells don't proliferate too quickly. Their results highlight how communica...In mice lacking PPARβ/δ, epidermal cells proliferate excessively after wounding (1). But cultured kerat...

Malaria parasite zeroes in on molecule to enhance its survival, team finds

...that the parasite doesn't break down arginine in order to grow, suggesting that this process serves some secondary function that helps P. falciparum proliferate within the human body. Arginine is an essential fuel for the human body's immune system, which uses it to produce a molecule called nitric oxide that ...

Biologists solve mystery of black wolves

... and co-author of the Science paper. "Although genes that evolve under domestication may be transferred to wild species, they generally do not proliferate in the wild because the natural context is so different from that under domestication," Wayne said. "No one would have guessed that the common black c...
proliferate in Biological Technology

WaferGen Signs Exclusive Distribution Agreement for SmartSlide(TM) Micro-Incubation System in Germany

...nduct complex time lapse imaging studies to characterize, differentiate and proliferate cells, as well as grow stem, primary and other difficult to cultivate cells...nduct complex time lapse imaging studies to characterize, differentiate and proliferate cells, as well as grow stem, primary and other difficult to cultivate cells...

WaferGen Signs Exclusive Distribution Agreement for SmartSlide(TM) Micro-Incubation System in United Kingdom and France

...nduct complex time lapse imaging studies to characterize, differentiate and proliferate cells, as well as grow stem, primary and other difficult to cultivate cells...nduct complex time lapse imaging studies to characterize, differentiate and proliferate cells, as well as grow stem, primary and other difficult to cultivate cells...

Medical College of Wisconsin ties breast cancer to inflammation

...aglobin B, which is present in normal breast tissue, is activated after injury to the breast and therefore can help to find malignancy. Abnormal cells proliferate in cancer because the normal cell cycle regulators are disrupted. Skp2 is one of the factors responsible for that. Though explored in breast cancer...

It's 99 percent certain: Research cannot rely on adult stem cells alone

...ey have the ability to form any adult cell and can proliferate indefinitely in culture, stem cells could potentia...cement stem cells and regular cells, which quickly proliferate and vastly outnumber the stem cells. Adult stem...long in culture. They have shown little ability to proliferate into quantities that can be effectively used in re...

Phishing and pharming: Is your personal identity being harvested?

...the same time, it is becoming more difficult to predict, prevent and punish those involved." There is the potential that as these scams continue to proliferate that they could have a negative impact on the rapidly growing market for online financial transactions. "Security issues related to internet transa...

Merge launches Spanish version of imaging tool

... improved support for CD and DVD burning with a localized Spanish interface. Robert White, president of Merge eMed, said this new version will help proliferate the Workstation, already one of the most widely used diagnostic desktop applications. The introduction of the product follows a string of financial...

DNASTAR catches second wave of sequencing

...ware and computer in a bundle, but that didn't stop Blattner from mowing a different landscape. Little by little, the personal computer would begin to proliferate in research labs and businesses, and he would be joined by other university professors who discovered a market for their research tools. And now, ...

Wisconsin tries to woo another stem cell company

...ive neural progenitor cells from human embryonic stem cells, enabling it to produce kits containing neural progenitors and the reagents needed to both proliferate and differentiate them into cultures of neural cells. The cells and proliferation media are used by biomedical researchers looking to develop ther...

Wisconsin won't get Georgia biotech without a fight

... neural progenitor cells from human embryonic stem cells, enabling Aruna to produce kits containing neural progenitors and the reagents needed to both proliferate and differentiate them into cultures of neural cells. The cells and proliferation media are used by biomedical researchers looking to develop therapie...

WARF questions relevancy of documents used to uphold patent challenge

.... "Clearly, at the time of the discoveries, leading scientists and scholars from around the world saw Thomson as the first scientist to isolate and proliferate human embryonic stem cells," Gulbrandsen said in a release. "When the process has run its course, the patented inventions will remain intact." Res...
proliferate in Biological Products

Neural Stem Cell Expansion Kit - Monolayer from R&D Systems

Description:...either monolayer cultures on an adhesive substrate or as free floating spherical aggregates termed 'neurospheres. These in vitro propagated NSCs can proliferate in culture while retaining the potency to differentiate into neurons, oligodendrocytes and glia. in vitro NSC expansion makes it possible to grow su...
Company:R&D Systems

Neural Stem Cell Expansion Kit - Neurosphere from R&D Systems

Description:...either monolayer cultures on an adhesive substrate or as free floating spherical aggregates termed 'neurospheres. These in vitro propagated NSCs can proliferate in culture while retaining the potency to differentiate into neurons, oligodendrocytes and glia. in vitro NSC expansion makes it possible to grow su...
Company:R&D Systems

Neural Stem Cell Expansion Kit - Monolayer Plus from R&D Systems

Description:...either monolayer cultures on an adhesive substrate or as free floating spherical aggregates termed 'neurospheres. These in vitro propagated NSCs can proliferate in culture while retaining the potency to differentiate into neurons, oligodendrocytes and glia. in vitro NSC expansion makes it possible to grow su...
Company:R&D Systems
proliferate in Biological Definition

Growth curve

...Figure 2, a tumor is found after the cell growth rate has slowed. Most of the cancer cells are removed by surgery. The remaining cancer cells begin to proliferate rapidly and cancer chemotherapy is started. Many tumor cells are killed by the chemotherapy, but eventually some cancer cells that are resistant to th...

HeLa

...ed for use in cancer research . Initially, the cell line was said to be named after a "Helen Lane", in order to preserve Lacks's anonymity. The cells proliferate abnormally rapidly, even compared to other cancers. HeLa cells have been transformed by human papillomavirus 18 (HPV18), and have different proper...

Immune system

...spects. One of the most important examples are the mechanisms of antigen presentation. After they leave the thymus, T cells require activation to proliferate and differentiate into "killer" T cells (CTLs). Activation is provided by antigen presenting cells (APCs). A major category of APCs involved in T cell...

Peroxisome

...formed directly. They also have membrane proteins that are critical for various functions, such as for importing proteins into their interiors and to proliferate and segregate into daughter cells. Peroxisomes function to rid the cell of toxic substances, such as hydrogen peroxide , or other metabolites and...

T cell

...ich express specific antigens that they recognize. Helper T cells (CD4 + ) are "middlemen" in the immune response. When they get activated, they proliferate and secrete cytokines, that regulate or 'help' effector lymphocyte function. They are known as one of the targets of HIV infection, and the decrease...
proliferate in Biological Dictionary

Spermatogonia

...e to become chains of 4, 8, 16, or 32 Aal ... One or two divisions of spermatogonia occur to maintain their population in a ... Spermatogonia proliferate several times and undergo 1 to 5 stages of division ... What is spermatogonia ? Meaning of spermatogonia medical term. What does spermatogoni...

Sarcoplasm

...chondria] ... © 2002 Oxford University Press ... BACKGROUND: Sonic muscle fibers intrinsic to the swim bladder of the oyster toadfish Opsanus tau proliferate ... surround a central core of sarcoplasm . ... The sarcoplasm of the cell is filled with contractile myofibrils and this ... 4) Ca+2 is pum...

Oogonia

...OM GIANT KELP GAMETOPHYTES ... oogonia per female often led to the production of multiple sporophytes per female. ... In most mammals oogonia proliferate by mitosis and begin meiotic development during fetal life. ... We hypothesized that fetal oogonia distressed as a result ... The stem cells...

Keratin

... Rubbing and pressure cause keratin to proliferate with the ... Fibrous keratin molecules can twist around each other to form helical intermediate filaments. ... Hair and hair disease informatio...

Hepatocytes

...ytes ... hepatocytes and the desynchronization and damping of circadian rhythm. ... ... liver transplantation, transplanted hepatocytes must proliferate efficiently ... Recently, small hepatocytes and oval cells have been proposed as important ... ... had no effect on FVIIa binding and internali...

Apical meristem

...rentiated ... Specifically, an active apical meristem lays down a growing root or shoot behind ... The cells of the shoot apical meristem proliferate throughout ... arate, lineage restricted apical initials in the maize meristem . ... The primary shoot apical meristem of A r a b i d o p ...
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