primes

Human breast tumors' 'microenvironment' primes them for metastasis

The environment within primary breast tumors can empower cells that break free and enter the bloodstream to successfully invade other organs, researchers report in the April 4th Cell, a publication of Cell Press. Specifically, through studies of hundreds of human breast tumors, the researchers ...

Flu Shot May Be Less Effective in Those With Lupus

... against the seasonal flu virus after vaccination in two ways. First, it generates antibodies specifically reacting to the flu virus, and secondly, it primes certain immune T-cells to respond to the flu bug. Prior work had already shown that the antibody-mediated vaccine response was dimmed in lupus pati...

At U.S. Colleges, Binge Drinking Is on the Rise

...s has far-reaching effects for the students. "The heavy drinking during college not only results in severe consequences at that time, [but] it also primes college students for later alcohol addiction," Galanter said. "Heavier drink at this age is a predictor of later alcoholism and is likely a major caus...

Prix Galien USA Recognizes Biotech, Pharmaceutical Industries for Innovative Medical Treatments

...omote bone healing. Special Therapeutic Development -- The Celgene Corporation for Revlimid(R) -- Taken orally, this cancer medication primes the immune system for killing cancer cells. The Prix Galien Award ( http://www.prix-galien-usa.com ) recognizes the technical, scientific and clinica...

Combination targets: some drugs may work best when they work together

...nse in some lung cancer patients treated with the tyrosine kinase inhibitor (TKI), erlotinib, by combining it with ABT-737, a small molecule drug that primes tumor cells to undergo apoptosis, or programmed cell death. About ten percent of tumors from lung cancer patients harbor mutations in the kinase ...

Clinical trial evaluating brain cancer vaccine is underway at NYU

... other tumors. They recur locally but we just cant cure it. A brain cancer vaccine is intended as a kind of immunotherapy, which means that it primes the patients own immune system to kill proteins found in cancer cells. The trial will enroll patients 18 to 65 years old with newly diagnosed glioblas...

What emotional memories are made of

...rators at Cold Spring Harbor and New York University have identified the likely biological basis for this: a hormone released during emotional arousal primes nerve cells to remember events by increasing their chemical sensitivity at sites where nerves rewire to form new memory circuits. Describing the ...

AIDS Vaccine Still a Long Way Off

... U.S., Africa, Asia, the Caribbean and South America. Vaccines work by exposing the body to the disease-causing agent or a fragment of it, which primes the immune system to produce a flood of antibodies that stick to the infecting organism and block it from entering cells. HIV infects so-called ...

Is Excalia an Excellent Weight Losing Pill?

...t this preparation can effectively help decrease body weight by almost 12 % in one year’s time if taken regularly for 48 weeks. The pill excalia primes the hypothalamus, the region in the brain associated with appetite and weight gain , to keep a fast paced metabolic rate. The pill consists of two dru...

Is Excalia an Excellent Weight Losing Pill?

...his preparation can effectively help decrease body weight by almost 12 % in one year’s time if taken regularly for 48 weeks. The pill excalia primes the hypothalamus, the region in the brain associated with appetite and weight gain , to keep a fast paced metabolic rate. The pill consists of two dr...

primes in Medical Technology

Proteolix to Present Clinical and Preclinical Data at the 50th Annual Meeting of the American Society of Hematology

...inical Studies Excluding Therapy Poster III -- Induction of Sustained Early G1 Arrest by Selective Inhibition of CDK4 and CDK6 primes Myeloma Cells for Synergistic Killing by Proteasome Inhibitors Carfilzomib and PR-047 (Abstract #3670) -- Preclinical Pharmacology an...

primes in Biological News

Mysterious 'neural noise' actually primes brain for peak performance

Researchers at the University of Rochester may have answered one of neuroscience's most vexing questions--how can it be that our neurons, which are responsible for our crystal-clear thoughts, seem to fire in utterly random ways? In the November issue of Nature Neuroscience, the Rochester study sh...

Researchers discover primer to plant defense system

... OAK RIDGE, Tenn., April 3, 2009 -- By identifying a novel compound that primes a plant's immune system, researchers at Oak Ridge National Laboratory and the University of Chicago may be on a path to developing disease-resistant p...

Scientists find a key to immune system's ability to remember

...n as "memory" cells, retains the imprint of its previous encounter should the pathogen make a return appearance. According to the study, while Lck primes naïve cells to fight a pathogen, it is not required by memory cells, which initiate the fast and furious response when that same pathogen comes callin...

UCSD study reveals how plants respond to elevated carbon dioxide

...t without the earplugs one would respond to the changes in the rhythms of the music," said Young. "Similarly, our findings suggest that carbon dioxide primes the calcium sensors to respond to the calcium spikes in the cell. Since changes in calcium concentration are used in other communication processes wit...

Combination therapy with a monocloncal antibody and a vaccine leads to tumor rejection

...s both Tregs and Teff cells to proliferate in response to exposure to self-antigen. Interestingly, combination of CLTA4 blockade with Gvax selectively primes the anti-tumor Teff cells for action. This led to greater infiltration of Teff cells into the tumor, and eventually to tumor rejection. Importantly, t...

Study shows combination of immune substances to be safe

... without additional side effects." The findings are published in the December 1 issue of the Journal of Clinical Oncology. They suggest that IL-12 primes white blood cells such that a lower dose of interferon will stimulate the same level of immune activity as a higher dose of interferon when used alone...

primes in Biological Technology

GeoVax Labs, Inc. Reports Fourth Quarter and Year-End 2008 Financial Results

... were similar for the 1/10th and full dose. O Two DNA primes were more effective than one DNA prime or no DNA primes at eliciting T cell responses. O The second MVA vaccination pos...

GeoVax Labs, Inc. Announces Third Quarter 2008 Financial Results and Provides Operational Update

...ca. The presentation, entitled "Two HIV DNA primes Maximize T Cell Responses Induced by the GeoVax DN... for the 1/10th and full dose. o Two DNA primes were more effective than one DNA prime or no DNA primes at eliciting T cell responses. o The 2nd...

GeoVax Presents Data at AIDS Vaccine 2008 Conference

...ter Phase 2 trials for its vaccine. The presentation, titled "Two HIV DNA primes Maximize T Cell Responses Induced by the GeoVax DNA/MVA Vaccine Regimen Adm...e rates for T cells were similar for the 1/10th and full dose. -- Two DNA primes were more effective than one DNA prime or no DNA primes at eliciting T cell...

Anthrax vaccine produces immunity with nanoparticles, not needles

...lls to react to the protein and initiate a protective immune response. That primes the immune system to promptly fight off infection when it encounters the wh...stemic and cellular immunity, meaning that the body produces antibodies and primes specific cells throughout the body to fend off anthrax infection. The vacci...

Anthrax vaccine produces immunity with nanoparticles, not needles

...lls to react to the protein and initiate a protective immune response. That primes the immune system to promptly fight off infection when it encounters the wh...stemic and cellular immunity, meaning that the body produces antibodies and primes specific cells throughout the body to fend off anthrax infection. The vacci...

primes in Biological Dictionary

Palindromic Sequence

... palindromic sequence in a ... A052092 - Lengths of the palindromic primes from Honaker's sequence A053600. A052205 - a(n+1) is smallest palindromi...imes called a palprime ) is a prime ... The first few decimal palindromic primes ( sequence A002385 in OEIS) are: ... The palindromic sequence (posi...