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Preclinical study of a new brain tumor therapy

Scientists have devised a strategy to treat tumors by selectively targeting and killing the malignant cells. A new preclinical study, published in the open access journal PLoS Medicine, has applied the approach to combat glioblastoma multiforme (GBM). This is the most aggressive form of brain tumour, growing very quickly before symptoms are experienced and killing most patients within a year of d...

Tramiprosate (Alzhemed? preclinical results published in Neurobiology of Aging

Neurochem Inc. (NASDAQ: NRMX; TSX: NRM) is pleased to announce that Neurobiology of Aging, one of the world's leading peer-reviewed medical journals in the fields of gerontology and neuroscience, has published an online version of a publication on the preclinical development of tramiprosate (3-amino-1-propanesulfonic acid; Alzhemed?, including efficacy results in a mouse model of brain amyloidosi...

Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

A molecular "off" switch packaged in a tiny sphere penetrates deeply into ovarian cancer tumor cells, stifling a troublesome protein and drastically reducing the size of tumors, researchers at The University of Texas M. D. Anderson Cancer Center report in the Aug. 15 edition of Clinical Cancer Research. The mouse model experiment, featured on the cover of the journal, demonstrates a poten...

Dual gene therapy suppresses lung cancer in preclinical test

Combination gene therapy delivered in lipid-based nanoparticles drastically reduces the number and size of human non-small cell lung cancer tumors in mice, researchers at The University of Texas M. D. Anderson Cancer Center and the University of Texas Southwestern Medical Center report in the Jan. 15 edition of Cancer Research. Two tumor-suppressing genes given intravenously reduced cancer...
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Dual Gene Therapy Suppresses Lung Cancer in Preclinical Test

Combination gene therapy delivered in lipid-based nanoparticles drastically reduces the number and size of human non-small cell lung cancer tumors in mice, researchers at The University of Texas M. D. Anderson Cancer Center //and the University of Texas Southwestern Medical Center report in the Jan. 15 edition of Cancer Research. Two tumor-suppressing genes given intravenously reduced...
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Preclinical at Medicine Technology

Neose Announces Presentation of Positive Preclinical Data on GlycoPEGylated Factor VIIa at the XXI Congress of the International Society on Thrombosis and Haemostasis

HORSHAM, Pa.--(BUSINESS WIRE)--Jul 11, 2007 - Neose Technologies,Inc. (Nasdaq GM:NTEC) today announced that two poster presentationswere presented with its collaborative partner, Novo Nordisk A/S,relating to GlycoPEGylated recombinant Factor VIIa at the XXIstCongress of the International Society on Thrombosis and Haemostasisin Geneva, Switzerland. The data presented demonstrates thatGlycoPE...

Gene Therapy Eradicates Pancreatic Cancer in Preclinical Trial Targeting System's Success in Mouse Model Reported in Cancer Cell

HOUSTON, July 9, 2007 - A molecularly engineeredtherapy selectively embeds a gene in pancreatic cancer that shrinksor eradicates tumors, inhibits metastasis, and prolongs survivalwith virtually no toxicity, researchers from The University ofTexas M. D. Anderson Cancer Center report in the July 9 edition ofCancer Cell. "This vehicle, or vector, is so targeted and robust in itscanc...

YM BioSciences Announces Preclinical Data Confirming Nimotuzumab Binds to the EGF Receptor and Potentiates Radiotherapy

MISSISSAUGA, ON, July 09, 2007 /PRNewswire-FirstCall/ - YMBioSciences Inc. , an oncology company that identifies, developsand commercializes differentiated products for patients worldwide,today announced that a study presented by investigators from KinkiUniversity School of Medicine and Kyoto University at the 11thmeeting of The Japanese Association for Molecular Target Therapy ofCancer...

ZIO-101 (Darinaparsin) Interim Phase II and Preclinical Data Presented at International Myeloma Workshop

KOS, Greece--(BUSINESS WIRE)--Jun 28, 2007 - ZIOPHARM Oncology,Inc. (NASDAQ: ZIOP), announced today the presentation of twoposters at the XIth Annual International Myeloma Workshop beingheld in Kos, Greece from June 25-28th, 2007. The meeting highlightsimportant advances made in the biology and treatment of multiplemyeloma. ZIOPHARM is presenting darinaparsin (ZIO-101) geneexpression profil...

ACE-011 Improves Multiple Myeloma Bone Disease in a Preclinical Model

KOS, Greece--(BUSINESS WIRE)--Jun 26, 2007 - Acceleron Pharma,Inc., a biopharmaceutical company developing therapeutics for thetreatment of musculoskeletal, metabolic and cancer-relateddiseases, today announced results demonstrating that ACE-011, anovel anabolic bone agent for the treatment of bone loss, preservedbone mass and architecture in a murine model of multiple myeloma.Multiple myel...

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(Date:10/3/2008)... Discrimination; Recognizes,Importance of Mental H.../PRNewswire-USNewswire/ -- Mental Health,America t...approval of a,mental health parity legislation tha...ion against Americans with mental health and subst...lans., The legislation, which recognizes the impo...
(Date:10/3/2008)...search Foundation(R) Collection of, Bouquets to T...Research, LOS ANGELES, Oct. 3 /PRNewswire/ -- Tel...g only hand-arranged, hand-delivered floral,arrang...nth-long,collaboration with The City of Hope, John... Cancer Center in southern California and national...
(Date:10/3/2008)...- As the population ages, a big,question employers...e the,financial crunch of an illness?", In most c...eck to,paycheck and now need two incomes to provid... spouses becomes critically ill and unable to work...ut the healthy,employee/spouse is strained by the ...
Breaking Medicine News(10 mins):Health News:Connolly Consulting Makes the 2008 Inc. Magazine's List of America's 5000 Fastest Growing Companies 2Health News:Mental Health America Hails Approval of Federal Parity Legislation 2Health News:Mental Health America Hails Approval of Federal Parity Legislation 3Health News:Teleflora and Nationally Recognized Hospitals to Honor Women Battling Breast Cancer 2Health News:Teleflora and Nationally Recognized Hospitals to Honor Women Battling Breast Cancer 3Health News:Can Your Employees Survive the Financial Crunch of an Illness? 2
(Date:10/5/2008)...Cell Biology how the altered behavior of integrin... On 2D surfaces, cells may migrate randomly, or be...e cell to the extracellular matrix, are known to i...s been unclear. Recent work has suggested that an ... an integrin called avb3 has been associated with ...
(Date:10/5/2008)..., New material could speed development of hydroge...rs in Greece report design of a new material that ...010 goals for hydrogen storage and could help elim...d vehicles. Their study on a way of safely storing...Oct. 8 issue of ACS, Nano Letters , a monthly jou...
(Date:10/5/2008)...climate has taught us anything, it,s that a system...ds in disaster. It turns out this rule applies as ...d of cash, our body deals in energy borrowed from ...ling financial markets, the lending process in the...re isn,t lent than can be afforded. New research b...
(Date:10/5/2008)... of an aquatic creature suggests that animals walk...an had been thought. , The tracks -- two paralle...diameter -- date back some 570 million years, to t...e Cambrian period, the time when most major groups...ught that it was primarily microbes and simple mul...
Breaking Biology News(10 mins):American Chemical Society's Weekly PressPac 2American Chemical Society's Weekly PressPac 3American Chemical Society's Weekly PressPac 4American Chemical Society's Weekly PressPac 5American Chemical Society's Weekly PressPac 6American Chemical Society's Weekly PressPac 7American Chemical Society's Weekly PressPac 8Food for thought -- regulating energy supply to the brain during fasting 2Food for thought -- regulating energy supply to the brain during fasting 3Earliest animal footprints ever found -- discovered in Nevada 2Earliest animal footprints ever found -- discovered in Nevada 3Childrens Miracle Network Hospital Doctors On Call to Answer Questions About MRSA Infection 4321 1Childrens Miracle Network Hospital Doctors On Call to Answer Questions About MRSA Infection 4321 2Committee to Reduce Infection Deaths Releases 10 Lifesaving Steps to Protect Students from MRSA Infections 4317 1Committee to Reduce Infection Deaths Releases 10 Lifesaving Steps to Protect Students from MRSA Infections 4317 2ASCO and ASH Release Updated Guideline on the Use of Chemotherapy Related Anemia Treatments in Cancer Patients 600 1ASCO and ASH Release Updated Guideline on the Use of Chemotherapy Related Anemia Treatments in Cancer Patients 600 2ASCO and ASH Release Updated Guideline on the Use of Chemotherapy Related Anemia Treatments in Cancer Patients 600 3Broccoli sprout derived extract protects against ultraviolet radiation 4313 1Broccoli sprout derived extract protects against ultraviolet radiation 4313 2
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