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New, automated tool successfully classifies and relates proteins in unprecedented way

For the first time, researchers haveautomatically grouped fluorescently tagged proteins fromhigh-resolution images of cells. This technical feat opens a new way toidentify disease proteins and drug targets by helping to show whichproteins cluster together inside a cell.The approach, developed by Carnegie Mellon University, outperformsexisting visual methods to localize proteins inside cells...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

Scientists at Joslin Diabetes Center have discovered one reason why infants with low birth weight have a high potential of developing type 2 diabetes later in life. In studies of mice, the researchers found that poor prenatal nutrition impairs the pancreas's ability to later secrete enough insulin in response to blood glucose. "The bottom line is that if you don't have delivery of enough...

Anti-bacterial additive widespread in U.S. waterways

Many rivers and streams in the United Statesare believed to contain a toxic antimicrobial chemical whoseenvironmental fate was never thoroughly scrutinized despite large scaleproduction and usage for almost half a century, according to ananalysis conducted by researchers at the Johns Hopkins Bloomberg Schoolof Public Health. The chemical, triclocarban, has been widely used fordecades in han...

Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible

Foreveryone doing or reading a paper about microarray-based experiments,reproductibility, especially inter-lab, is the #1 concern. Can I trustthese results? If I redo the same experiment in one month, will I beable to compare both? The NIH recently demonstrated that microarrays experiments performed in d...

“Nano-scissors?laser shows precise surgical capability

)is quite a challenge; its about 1 mm in length. A research team fromthe University of Texas at Austin developed a method of laser-assistedsurgery to work on these little beasts, being able to section a singleaxon (the "arms" of a neuron) with g...

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PB3002-S/FACT DeltaRange Precision Balance from Mettler Toledo, Inc.

Description:Accurate, easy-to-use and reliable to provide good weighing for many years that sums up the Classic Balances from METTLER TOLEDO in a single sentence. The robust full metal housing make these balances your reliable partner for everyday use. * Adjustment with internal weights FACT * Adjustment with external weights 2000 g * Sensitivity (temperature Sampling pump drift) 6 ppm/C <...
Company:Mettler Toledo, Inc.

DNA/RNA Aptamer Microarray - Comprehensive Service from LC Sciences

Description:LC Sciences provides unique aptamer microarray services using a novel Paraflo technology, aptamer sequence databases, and sequence design software to suit your needs for basic research and screening of aptamers as drug candidates. This comprehensive service includes assistance with sequence design, synthesis of standard or custom DNA/RNA (2-OMe) microarrays, binding assays using proteins, nucleic...
Company:LC Sciences

PL1501-S Precision Balance from Mettler Toledo, Inc.

Description:Simple operation and an easy-to-read LCD display characterize our Classic Light balances. * Taring range 0...1510 g...
Company:Mettler Toledo, Inc.

Protein Kinase Substrate (PKS) Peptide Microarray - Comprehensive Service from LC Sciences

Description:LC Sciences provides a comprehensive kinase analysis service utilizing high density protein kinase substrate (PKS) peptide microarrays synthesized on Paraflo microfluidic chips for proteomic scale kinase profiling, quantitative measurement of kinase kinetic activities, and drug discovery research. This comprehensive service includes preparation of your kinase sample, single or dual color enzymati...
Company:LC Sciences

Small Non-coding RNA Discovery Microarray - Comprehensive Service from LC Sciences

Description:LC Sciences provides a comprehensive microarray service for systematic discovery of small regulatory/functional RNA embedded within non-coding RNAs (ncRNAs) using a novel Paraflo technology and proprietary probe design, which enables highly sensitive and specific direct detection of small RNAs (1). This comprehensive service includes custom probe design (according to submitted target RNA sequence...
Company:LC Sciences

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New Microarray Labeling Kit for Preparing cDNA Probes

A more reliable and reproducible way to create fluorescently orradioactively labeled cDNA David T. Wong Heidi Davis Darryl Garrison TerryPayette Matt Lundy Kim Kuplent Mary A. Buchanan Joseph A. Sorge Rebecca L. Mullinax Stratagene Phenogenex Nucleic acid micro...

Human Primary Preadipocytes and Differentiated Adipocytes

Zen-Bio, Inc. Stratagene Michael R....

An Epitope Tagging Vector for Gene Expression in Mammalian Cells

Stratagene The pCMV-Tag1 vector is an epitope tagging vector designed for geneexpression in mammalian cells. A target gene inserted into the pCMV-Tag1 vectorca...

Antibodies for Studying NMDA Receptor Protein Expression and Synapse-Specific Immunolabeling

Danny Q. Hoang Michael Browning Xinping Yang PeterPingerelli Stratagene Cloning Systems, Inc. Stratagene introduces affinity purified antibodies for NMDA receptorsubunits that are useful for studying expression of the NR2A, NR2B and NR2Csubunit proteins...

High-Level Expression of Peanut Allergens Affected by Rare Codon Usage

Biochemical & Molecular Allergology, Research Center Borstel, Germany By using Stratagenes BL21-CodonPlus(DE3)-RIL cells * withextra copies of E. coli, argU, ileY, and leuW tRNA genes,it is possible to attain high-level expression...

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Lac repressor

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Expressed sequence tag

, but has since been instrumental in gene di...

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Tumor suppressor

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Immunosupressants for Eczema

Here's to all of you who thought that one only uses corticosteroids for skin disease. Yet, the host of drugs that have come out in the recent years which are dermatocentric are astounding and here is another. Using Tacrolimus, the agent which was devised for liver transplantation, there has been found to vast symptomatic relief of patients. Eczema is a devastating disease because of its c...

Asthma may actually be prevented by Dust and Dirt

National Jewish Medical and Research Center researchers in USA say that a little dust and dirt in the home may help prevent asthma later in life. Environmental endotoxin may have an allergy-protective effect in some infants whose homes have high levels of the bacteria by-product. "Endotoxin seems to drive the immune system to produce cytokines that inhibit certain processes in the body th...

Virus Level could Predict Cervical Cancer Risk

Cervical cancer is one of the most common cancers in women. If it is caught and treated early, it is curable in most cases.// The Pap smear is the standard screening method for the disease. It is used to detect unusual, precancerous changes in cervical cells. Two strains of the human papilloma virus (HPV) are associated with an increased chance of getting the cancer, but not all women who...

Low Cholesterol Linked to Severe Depression and Violent Behavior in Men

It is not high levels of cholesterol but low levels that are making news. Recent reports are indicating that Low levels of Cholesterol maybe linked to depression and violent behavior. A new study shows that men with relatively low cholesterol levels were up to seven times more likely to report symptoms of severe depression. Edward Suarez, PhD from Duke University Medical Center in Durha...

Recommendations for Treatment of Blood Pressue

The National Heart, Lung, and Blood Institute (NHLBI) and the National High Blood Pressure Education Program (NHBPEP),USA, have come out with recommendations to treat Hypertension.Control of systolic blood pressure is as important as control of Diastolic blood pressure. This is a crucial message for health care providers, patients, and their families. For many years, the importance of low...

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Smith Expressor Hook

Description:11.5 mm curved hook. Flat serrated handle with polished finish. Overall length: 5.9 inches....
Company:Bausch & Lomb Storz

Saunders Eye Speculum - Premature Infant

Description:Solid 4 mm blades. Locking thumb. Dull finish. Holes in bar decrease weight of speculum....
Company:Bausch & Lomb Storz

Preclude MVP Dura Substitute

Description:Preclude MVP Dura Substitute is the only dura material versatile enough for use in procedures requiring an immediate, watertight closure, and in cases where biological fixation and sealing are desirable. Minimizing CSF leakage in cases requiring an immediate watertight seal and also allowing for techniques that require biological fixation and sealing are key factors in duraplasty....
Company:W. L. Gore & Associates, Inc.

Preclude Dura Substitute

Description:Preclude Dura Substitute is the only non-biological membrane designed to "seal" around suture holes. 0.3 mm as nominal thickness....
Company:W. L. Gore & Associates, Inc.

Cervical Spinal Compression Plate Acc. To Matzen

Description:The cervical spinal compression plate acc. to Matzen is used for the anterior stabilization of the cervical spine (HWS) with the exception of C0-C2. The implant provides for the immobilization of the fusion length until the bone transplant has consolidated. The plate is fixed anteriorly on the vertebral bodies, if possible along the center line. It has instrument repositor: distraction, which is...
Company:Ulrich GmbH & Co. KG

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Controlling the Spread of Healthcare Associated Methicillin Resistant Staphylococcus aureus Requires Active Surveillance

Both methicillin sensitive and methicillin resistant Staphylococcus aureus (MSSA, MRSA) can cause invasive and life-threatening infections such as osteomyelitis, septicemia, endocarditis, and pneumonia. Healthcare associated MRSA is of particular clinical importance because it is not only predictably cross resistant to all penicillins and cephalosporins, but is also typically resistant to mu...

The Past, Present and Future of HLA Typing

The Human Leukocyte Antigen (HLA) region, located on the short arm of chromosome 6 (6p21.3), is a highly polymorphic region containing about 200 genes. The HLA region is the human equivalent of the Major Histocompatibility Complex (MHC), and as such contains a set of genes that serve as the backbone of antigen presentation. The Class I proteins, classically involved in presenting endogenous...

Managing Preanalytical Processes for Patient Safety

Contributing Editor Positive patient identification (ID) is a major put by healthcare accrediting bodies for the past few years. Until recently, the costs associated with hardware and software were beyond the reach of the average hospital or laboratory. Today there are multiple vendors with devices that can be integra...

Large Geographic Differences in EpiPen Prescriptions in the U.S., From the Journal of Allergy and Clinical Immunology

MILWAUKEE, July 11, 2007 /PRNewswire/ -- A new study suggestsstrong variation in the occurrence of anaphylaxis between thenorthern and southern U.S. Anaphylaxis is a severe allergicreaction that can be fatal without treatment with epinephrine. Thestriking north-south differences in EpiPen prescribing, a marker ofanaphylaxis risk, currently are without explanation. Theinvestigators hypoth...

Sygnis Pharma AG announces date for presentation of clinical results

HEIDELBERG, Germany, 11 July 2007 – On 23 July SYGNIS PharmaAG will present the results of the clinical phase IIa study forAX200 (AXIS-study). AX200, a compound for the treatment of stroke, is the mostadvanced drug candidate in SYGNIS’ product pipeline. Theprimary aim of the study is to show safety and tolerability ofAX200 in acute stroke patients. The results of the AXIS-stud...

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Pre-conditioning

is a general concept in which an entity is exposed to a form of some stress or stimulus in order to prepare that entity to be more resilient against the stimulus when and if the stimulus is encountered in the future. For example, a human may be exposed to artificially weakened virus in order to stimulate an antibody production in the body against that virus, so that late...

Predictive medicine

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Unintended Pregnancy

John’s Wort, and other drugs that speed the body’s breakdown and use of contraceptive...

Tubal pregnancy

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