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New Study from Affymetrix Laboratories Points to Changing View of How Genome Works

Scientists at Affymetrix, Inc. (Nasdaq: AFFX) reported today in Science magazine online that they have completed a high-resolution scan of structure and function for nearly 30 percent of the human genome sequence. In collaboration with the National Cancer Institute, the research team used high-density GeneChip(R) microarrays to study every fifth base, on average, of 10 human chromosomes; they fou...

While on trail of dioxin, scientists pinpoint cancer target of green tea

Green tea appears to protect against cancer by affecting a "promiscuous" protein that pharmaceutical experts are already targeting in an effort to develop a new drug to stop the disease, scientists at the University of Rochester Medical Center have found. The research, which buttresses beliefs about the health benefits of green tea with solid scientific evidence, has been cited as part of the bes...

Pinpointing the cause of a neurodegenerative disorder

New understanding of spinocerebellar ataxiaResearchers have discovered how the abnormal repetition of a genetic sequence can have disastrous consequences that lead to the death of neurons that govern balance and motor coordination. The studies bolster the emerging theory that neurodegenerative disorders can be caused by having extra copies of a normal protein, not just a mutated one. Peopl...

Pinpointing a culprit molecule in Alzheimer's disease

One puzzle in Alzheimer's disease (AD) research is why mice engineered to have the abnormal protein underlying the disease in humans show little pathology of the disease. Specifically, such mice are genetically altered to overproduce mutant human amyloid precursor protein (APP). It is this protein that, when clipped by enzymes, produces the amyloid beta (Ab) peptide that clusters into the amyloid...

Scientists crack 40-year-old DNA puzzle and point to 'hot soup' at the origin of life

A new theory that explains why the language of our genes is more complex than it needs to be also suggests that the primordial soup where life began on earth was hot and not cold, as many scientists believe. In a paper published in the Journal of Molecular Evolution this week, researchers from the University of Bath describe a new theory which they believe could solve a puzzle that has baf...

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PinPoint™ Vector Sequencing Primer from Promega

Description:The PinPoint™ Vector Sequencing Primer is designed for sequencing inserts cloned into the PinPoint™ Xa Vectors (Cat.# V2031, V2051, V2061). The primer hybridizes upstream of the Factor Xa site at nucleotides 325343, approximately 4050 base pairs upstream of the multiple cloning region and can be used to determine if an insert is cloned in-frame with the biotinylation purification tag...
Company:Promega

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Detection of K-ras Point Mutations in the Pancreas by Constant Denaturing Gel Electrophoresis Using the DCode System

Martin A.O.H. Menke*, Axel Reinecke-Lthge*, Barbara Mllmann*, Angela Kellner, Jutta Lttges*, Gnter Klppel* * Department of Pathology and Department of Hematopathology, Christian- Albrechts University Kiel, Michaelisstrae 11, D-24105 Kiel, Germany. Introduction Genetic alterations/variations are...

Biotech industry reaches midpoint in 50-year maturation cycle

An interesting article in ) on March 1 states unequivocally that most industry cycles run about 50 years until they mature. If this...

Covance Appoints Co-Presidents for Early Development Services

PRINCETON, NJ - Covance Inc. has promoted Wendel Barr to the position of president, early development, in Madison, Wis., and Anthony Cork to the position of president, early development, in Harrogate, UK. The company said the move supports the regional decision-making employed by its clients in the preclinical segment. With the promotion, Wendel and Tony have become corporate senior vic...

Quantitative end-point RT-PCR gene expression measurement using the Agilent 2100 Bioanalyzer and standardized RT-PCR

This application note describes how the Agilent 2100 bioanalyzer canbe used in combination with Standardized RT (StaRT)-PCR reagentsfrom Gene Express National Enterprises (G.E.N.E.), Inc. (Huntsville,AL, USA) to obtain highly reproducible, standardized gene expressionme...

Sharon Ethanol appoints operations director

, a subsidiary of <a href="http://www.grainnet.com/articles/Global_Renewable_LLC_Unveils_Plans_for...

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Point Mutation

Gene...

Breakpoint

s. Two gr...

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New point scale to ascertain the stroke recovery

Stroke is undoubtedly the most common neurological disorder and one of the leading causes of morbidity and mortality. Five million people die of stroke each year and more than 15 million suffer non-fatal strokes. But the question of the day is about the recovery - whether the patient would recover and if so how long would it take. Researchers at the National Institute of Neurological Dis...

New viewpoint on Hypertension

According to researchers, a new study shows that the distinction between the two blood pressure figures increases the risk of death in kidney patients.// A blood pressure reading always consists of two figures - the systolic reading (top figure) and the diastolic reading (bottom figure). Researchers at University of Texas, now report upon the impact the difference between the two known as pulse p...

Dental appointment fear: is it gender specific?

You were always scared of going to the dentists, but did you know that //whether you are a man or a woman can affect the way you feel scared about dental appointments? A new study done by researchers of University of Toronto emphasize that although women are 2.5 times as likely to be afraid of dentists than men, men too are as likely to eel afraid, only they’ll admit it less....

Study points out that HIV vaccine may not be accepted easily

Researchers feel that in the next ten years, the HIV vaccine will be ready for use, but there may// be a lot of barriers preventing the acceptance of the vaccine by the people. The research done by University of Toronto researchers said that it is important that the health workers of the world gets the common people ready for accepting the vaccine, which may be quite difficult job to d...

Radiology advance points way to non-invasive brain cancer treatment

Glioblastoma Multiforme, GBM, is a brain cancer death sentence. It is the most lethal cancer there is. Of the approximately 12,000 people who are diagnosed with GBM annually in the U.S., half // will die within a year, and the rest within 3 years. The treatments include highly invasive surgeries to remove the tumor and radiation treatment with the maximum tolerated dose, both leading t...

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Wet-Field Hemostatic Eraser Bipolar Tip (20-23 gauge Tapered/Blunt Point, Curved 150)

Description:...
Company:Medtronic Xomed, Inc.

Wet-Field Hemostatic Eraser Bipolar Tip (20-23 gauge Tapered/Blunt Point, Straight)

Description:These specialty Eraser instruments have been designed to provide the ophthalmic surgeon with the right tool for situations requiring precise hemostasis. Medtronic recently introduced a series of 25 gauge intraocular, bipolar, diathermy instruments. These instruments provide discrete treatment of target tissues for fine-tip hemostasis or controlled drainage retinotomy, without compromise in power...
Company:Medtronic Xomed, Inc.

Wet-Field Hemostatic Eraser Bipolar Tip (20-23 gauge Tapered/Blunt Point, Curved 90)

Description:These specialty Eraser instruments have been designed to provide the ophthalmic surgeon with the right tool for situations requiring precise hemostasis. Medtronic recently introduced a series of 25 gauge intraocular, bipolar, diathermy instruments. These instruments provide discrete treatment of target tissues for fine-tip hemostasis or controlled drainage retinotomy, without compromise in power...
Company:Medtronic Xomed, Inc.

Wet-Field Hemostatic Eraser Bipolar Tip (20-23 gauge Tapered/Blunt Point, Curved 135)

Description:These specialty Eraser instruments have been designed to provide the ophthalmic surgeon with the right tool for situations requiring precise hemostasis. Medtronic recently introduced a series of 25 gauge intraocular, bipolar, diathermy instruments. These instruments provide discrete treatment of target tissues for fine-tip hemostasis or controlled drainage retinotomy, without compromise in power...
Company:Medtronic Xomed, Inc.

Spanish Near Point Card

Description:Spanish reading test....
Company:Richmond Products, Inc.

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Point of Care Strep Tests Speed Treatment, Lower Costs

Beta-hemolytic group A streptococcus (S. pyogenes) is the most common bacterial agent associated with upper respiratory tract infections. Although it usually involves mild symptoms (such as headache, fever or abdominal pain) if left untreated streptococcal infection can worsen and become life-threatening. Early diagnosis and treatment of group A streptococcal pharyngitis has been shown to red...

Analyzers Offer Point-of-Care Lipid Panels

Plasma lipids, comprised of triglycerides and cholesterols, vary with genetic predisposition, weight, diet and physical activity. All of these factors contribute to serum cholesterol and triglyceride levels and highly correlate with risk of untoward vascular and cardiac events. Perhaps no other commonly determined medical laboratory values are so much in the public eye as serum levels of good...

Hemoglobin Testing at the Point of Care

Since the level of blood oxygenation can be an essential element of patient assessment, measurement of hemoglobin levels in the clinical setting is often desirable. In keeping with the recent trend to incorporate sophisticated technology into easily used point-of-care devices, recent products from several manufacturers offer prompt assessment of hemoglobin values. HemoCue, Inc., Lake...

Point of Care Cardiac Analyzers Yield Rapid Cardiac Marker Results

Clinical guidelines from the disciplines of cardiology and laboratory and emergency medicine have all emphasized the importance of cardiac markers in diagnosing or ruling out acute myocardial infarction. The measurement of cardiac troponins is especially useful in the large fraction of patients presenting with acute coronary syndrome (ACS) who have...

New Point-of-Care Methods to Measure Coronary and Cerebrovascular Risk

Harvard Medical School Contributing Editor Atherosclerosis is the fundamental process in coronary artery disease, stroke, and many other vascular diseases. It is responsible for more than half of the disease burden of the United States, with an annual cost of over $100 billion. This includes over 1.5 million my...

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Hip Pointer

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Point tenderness

usually occurs within several hours ...<br...