International research team seeks to unravel flatworm regeneration
...ll 30 percent of the cells of this species consists of stem cells, making it a unique model system to investigate the function of stem cells.
genes resemble those of humans, and also many genes specifically linked to planarian stem cell biology and regeneration are conserved in humans. Under...
Whitehead member Peter Reddien named HHMI Early Career Scientist
...tive and creative science, and I am honored to have the future work of my laboratory supported by HHMI."
Reddien, who investigates regeneration in planaria
flatworms, was selected from a pool of more than 2,000 applicants to become one of HHMI's first 50 Early Career Scientists.
"I'm delighted that H...
Flatworm helps researchers study stem cells and cancer
...h and the Forsyth Institute at Harvard report that planaria
contain a gene highly similar to the human gene PT... cancer. They found that PTEN was present in many planaria
cell types, including stem cells. Additionally, d...f PTEN has been strongly conserved in evolution as planaria
PTEN is likewise critical to cell proliferation. ...
New understanding of regeneration gained by Forsyth scientists
..., and for developing novel biomedical approaches. planaria
have powerful regeneration capability that makes t...opt radically different fates, as is the case with planaria
where the cells have to decide whether to build a ...mine the impact on regeneration. As a result, the planaria
often grew back two heads rather than a head and t...
Regenerating worms help elucidate stem cell biology
...ists know, is dependent on stem cells in the adult planaria
known as neoblasts. Like all stem cells, neoblasts...oo soon to know how similar these mechanism are in planaria
neoblasts and other organisms' stem cells. "But at...ion of their neoblasts, Sánchez Alvarado considers planaria
an excellent model to tease out the intricacies of...