Newer Blood Pressure Drug No Better Than Placebo in Preventing Stroke

Patients may need to be on telmisartan longer to see positive effect, researchers say WEDNESDAY, Aug. 27 (HealthDay News) -- The blood pressure drug telmisartan does not lower the rate of stroke, cardiovascular events or diabetes better than a placebo in patients who have had a stroke,...

Review of probiotic research finds only Bifantis can claim efficacy vs. placebo for IBS symptoms

PHILADELPHIA October 15, 2007 A new analysis of randomized controlled trials evaluating probiotics in the treatment of irritable bowel syndrome (IBS) has found that Bifantis, Bifidobacterium infantis 35624, the sole ingredient in Align (manufactured by Procter & Gamble), is the only probiotic cu...

Hip Osteoarthritis Therapy No Better Than Placebo

FDA-approved injection for knees less effective in deep joint areas, study finds FRIDAY, March 6 (HealthDay News) -- A single injection of hyaluronic acid is no more effective than a placebo in treating hip osteoarthritis (OA), a new French study finds. Hyaluronic acid (HA), a sub...

Popular alternative therapy for psoriasis performs no better than placebo

Anecdotal evidence touting the healing power of the Indian spice turmeric for psoriasis received a setback in a prospective study published this month by a leading dermatology journal stating that the low response rate of patients who ingested the active ingredient of the exotic spice was probably...

Placing a Finger on Responses to Placebo Types

The placebo effect has been a raging topic for several years, gaining momentum over the past one year with lab trials being conducted to // analyze physiological responses to them. A new study, published in the Feb1 issue of the British Medical Journal examines the perceptible effect of types of p...

Mystery Of The Placebo Effect, Yet To Be Solved

Placebo is usually given to patients who psychologically feel that they are unwell but are actually hale and healthy// . Some people are always under the notion that they are unwell and ask medicines to be prescribed by their General Practioners. But too much of medicines also lead to various...

Homeopathic preparation better than placebo in perennial allergic

A homeopathic preparation for perennial allergic rhinitis appears to be more effective than placebo. A multicenter team studied 50 patients with perennial allergic rhinitis. The subjects were randomized to receive either 30cc of a homeopathic preparation of principal inhalent allergen or placebo. I...

Common PTSD Drug is No More Effective Than Placebo

Guanfacine, a medication commonly prescribed to alleviate symptoms of post-traumatic stress disorder, is no more effective than a placebo, according to a study// led by researchers at the San Francisco VA Medical Center. “There was no benefit at all, and there were several adverse side effect...

Codeine As Useful As A Placebo

Codeine, which is used extensively in cough syrups, is actually no better than placebo or dummy drugs, according to a new study. The drug seems to deal effectively with suppressing cough, but actually does not treat it//. Manchester University researchers conducted a study on 24 patients with ...

Study Shows No Difference between Policosanol and Placebo

According to a trial result it is said that the dietary supplement policosanol is no better than a placebo. This drug is used as an alternative to reduce cholesterol.// It is made from the waxy coating on sugar cane and sometimes from beeswax, wheat germ and rice bran. The study results were publi...

More>>

Placebo in Medical Technology

Phase III Clinical Studies of Aclidinium Bromide Show Statistical Significance vs. Placebo in Patients With Chronic Obstructive Pulmonary Disease (COPD)

NEW YORK, Sept. 3 /PRNewswire-FirstCall/ -- Forest Laboratories, Inc. (NYSE: FRX ) and Laboratorios Almirall, S.A. today announced results from two global Phase III studies of aclidinium bromide, a novel long-acting inhaled anticholinergic for the treatment of patients with chronic obstructiv...

Controversy About Lack of Placebo Group Decline in Alzheimer's Clinical Trials

- Two Large-Scale Analyses Have Conflicting Results - CHICAGO, July 28 /PRNewswire-USNewswire/ -- Lack of measureable decline in memory and thinking processes among placebo groups in Alzheimer's disease clinical trials might reduce the ability to show the effectiveness of new Alzheimer thera...

New Study Results Show Asenapine More Effective Than Placebo in the Treatment of Acute Schizophrenia

KENILWORTH, N.J., Dec. 17 /PRNewswire-FirstCall/ -- Schering-Plough Corporation (NYSE: SGP ) today reported on new study results that demonstrated that Asenapine, a fast-dissolving, sublingual tablet being developed for treatment of schizophrenia, was more effective than placebo and well tole...

Review of Probiotic Trial Research Finds Only Bifantis(R) Able to Claim Efficacy versus Placebo for IBS Symptoms

Of 13 studies analyzed, only Bifantis used appropriate study design to demonstrate efficacy compared with placebo PHILADELPHIA, Oct. 15 /PRNewswire/ -- A new analysis of randomized controlled trials evaluating probiotics in the treatment of irritable bowel syndrome (IBS) has fou...

New Study of Concerta(R) Showed Significant Improvement of ADHD Symptom Management in Adults Compared to Placebo

Interim Results From Open-Label Follow-up Include Longer-term Safety Findings BOSTON, Oct. 26 /PRNewswire/ -- Adults with Attention Deficit Hyperactivity Disorder (ADHD) treated with CONCERTA(R) OROS(R) methylphenidate HCl Extended-release Tablets showed signif...

New Long-Term Data Analyses for Bifeprunox Show Favorable Effects Versus Placebo in Stabilized Patients with Schizophrenia

Six-Month Data Show Bifeprunox Maintained Stability Significantly Longer than Placebo and had a Favorable Weight and Lipid Profile Comparable with Placebo MARIETTA, Ga. and COLLEGEVILLE, Pa., May 22, 2007 - Solvay Pharmaceuticals, Inc., Wyeth Pharmaceuticals, a division of Wyeth (NYSE:WYE), and ...

Safety Analyses of Clinical Data for Bifeprunox in Patients with Schizophrenia Showed a Favorable Weight and Lipid Profile, Similar to Placebo

COLLEGEVILLE, Pa., March 30, 2007 /PRNewswire-FirstCall/ -- Wyeth Pharmaceuticals, a division of Wyeth , Solvay Pharmaceuticals, Inc. and Lundbeck A/S presented clinical study results on bifeprunox at an international medical congress this week. Safety analyses suggest bifeprunox, an investigation...

Pooled Studies Showed Desvenlafaxine Succinate Significantly Improved Painful Symptoms and Anxious Symptoms Associated with Major Depressive Disorder in Adults, Compared With Placebo

Pooled Findings Presented at 2007 APA Meeting Also Showed No Significant Impact on Weight for Desvenlafaxine Succinate COLLEGEVILLE, Pa., May 21, 2007 /PRNewswire-FirstCall/ -- Findings from two separate pooled analyses - one examining the effect of desvenlafaxine succinate on anxious symptoms and...

Data Presented at SLEEP 2007 Shows VEC-162 Improves Sleep Onset and Maintenance vs. Placebo

Demonstrates Positive Effect on Objective and Subjective Sleep Measures MINNEAPOLIS, June 13, 2007 /PRNewswire-FirstCall/ -- According to study results presented today at SLEEP 2007, the 21st annual meeting of the Associated Professional Sleep Societies (APSS), VEC-162, a balanced melatonin (MT1/M...

Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009

...eduction in LDL-C after 26 weeks of treatment with mipomersen versus 3% for placebo and all of its secondary endpoints in a highly statistically significant ma...oint, with a 25% reduction in LDL-C after 26 weeks of treatment, vs. 3% for placebo (p<0.001). The study also met each of its three secondary endpoints of ...

More>>

Placebo in Medical Dictionary

Placebo

A placebo is a sham medical intervention intended to lead the recipient to believe that the intervention may improve his her condition. The fact that the pill is inert is withheld from the patient. The intervention may cause... A placebo is a sham medical intervention. In one common plac...

Intramuscular

...eltoid injections exceeding 3 ml cc ... Patients received intramuscular injections of either BHT-3009 (0.5 mg or 1.5 mg) ... mg of BHT-3009 or placebo via Intramuscular injection at weeks 0, 2, 4 and once ... Definition of intramuscular from the Merriam-Webster Online Dictionary with audio...

Impotence

...chological impotence is where erection or penetration fails due to thoughts ... Notably in psychological impotence , there is a strong response to placebo ... Read about erectile dysfunction (ED) / impotence includes what it is, how ED is diagnosed, and treatment options. ... Top Searched Impot...

Placebo in Biological News

Got zinc? New zinc research suggests novel therapeutic targets

...y in the elderly." Scientists administered either a zinc supplement or a placebo to healthy volunteers to assess the effects of zinc on T cell activation. A... from the zinc-supplemented group had higher activation than those from the placebo group. Specifically, cell activation stimulated the zinc transporter in T ...

Results from trials of DHA in Alzheimer's disease and age-related cognitive decline

...uble blind, randomized, placebo-controlled clinical trial comparing DHA and placebo in 402 people (average age=76) diagnosed with mild to moderate Alzheimer's ...y DHA intake of less than 200 mg per day. Subjects were treated with DHA or placebo at a dose of two grams per day for 18 months. Those participants already ta...

New supplement may help slow sight loss in elderly

...noids preserved the macular pigments, slowing down the progression from early AMD to late AMD. In contrast, the macular pigments of participants in a placebo group declined steadily. Dr Chakravarthy added: "These findings are important because this is the first randomised controlled clinical trial to docu...

Omega-3 fatty acids appear to impact AMD progression

...e AMD. AREDS study participants were randomly allocated to receive either a placebo or supplements containing the antioxidants vitamins C and E and beta carote... "In our study, we observed participants with early stages of AMD in the placebo group benefited from higher intake of DHA, but it appears that the high-dos...

Preventing ear infections in the future: Delivering vaccine through the skin

... Animals that received the vaccines were able to very rapidly reduce, or completely eliminate NTHi from the nose and ears, but animals that received a placebo did not. ...

Cocaine: Perceived as a reward by the brain?

...n its response to addictive drugs. This study was carried out in ten non-addicted users of cocaine, all of whom sniffed cocaine on one test day and placebo powder on another. Participants underwent blood tests before and after taking the drug, and dopamine release in the brain was measured using PET scans...

Your brain on -- and off -- caffeine

... which involved the administration of caffeine and placebo capsules. Each participant's response to the caffeine or placebo was measured using three different measures brain...rison of chronic caffeine maintenance with chronic placebo maintenance, which provides unique information abo...

Novel lung cancer vaccine shows promise in fighting early-stage lung cancer

...all Cell LunG Cancer Immunotherapy) study is a randomized, double-blind and placebo controlled trial that will enroll patients with MAGE A-3-positive, non-smal...ed to treatment with the MAGE-A3-targeting vaccine and 60 patients received placebo vaccines. The preliminary research shows that the treatment was well toler...

Lancet study supports new, highly effective treatment for blood disorder

... control group received the standard of care and a placebo pill. By the end of the 43-day testing period,...blood, compared with 16 percent of subjects in the placebo group. A safe-level platelet count is between 30,0... likely to reach the target platelet counts as the placebo group. Currently, patients are treated with co...

After a few drinks, older adults more impaired than they think

...a comparison group aged 25 to 35 who had at least one drink a month. Within each group, some individuals were given alcohol while others were given a placebo beverage that did not elevate their breath alcohol levels. The groups were carefully matched by gender, body mass index, history of alcohol consumptio...

Placebo in Biological Technology

Retrospective Analysis of Phase 3 Data Suggest Wyeth's Investigational Compound Bazedoxifene/Conjugated Estrogens Comparable to Placebo on Incidence of Abnormal Mammograms

Separate Retrospective Analysis of Phase 3 Data Offers Additional Information on Bazedoxifene Alone COLLEGEVILLE, Pa., Sept. 25 /PRNewswire/ -- A retrospective analysis of Phase 3 two-year data presented at the annual meeting of the North American Menopause Society (NAMS) suggest that postme...

New Phase 3 Data Showed PRISTIQ Significantly Reduced Symptoms of Major Depressive Disorder Versus Placebo

Data Presented for the First Time on 50 mg/Day Dose for PRISTIQ for the Treatment of Major Depressive Disorder COLLEGEVILLE, Pa., Dec. 12 /PRNewswire-FirstCall/ -- Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE ), announces that data from two Phase 3 clinical studies of...

Study Data Results Showed Desvenlafaxine Significantly Reduced Moderate to Severe Vasomotor Symptoms in Menopausal Women Versus Placebo

COLLEGEVILLE, Pa., Oct. 15 /PRNewswire-FirstCall/ -- Wyeth Pharmaceuticals, a division of Wyeth (NYSE: WYE ), reported that new study data presented today at the 63rd Annual Meeting of the American Society for Reproductive Medicine (ASRM) showed that women who received 100 mg/day or 150 mg/da...

Arizona Pain Specialists Contend Recent Vertebroplasty Studies are Misleading

...ted, "The conclusion that vertebroplasty does not help back pain is completely wrong. If you look closely at the study design, what they are calling a placebo is actually a facet injection." "These studies actually show that both treatments are effective," said Paul Lynch, MD, co-founder of Arizona ...

AutoImmune Inc. Reports 2009 Second Quarter Financial Results

...patients with secondary progressive multiple sclerosis (SPMS). In addition, there were no statistically significant differences between dirucotide and placebo on the secondary endpoints of the study. Eli Lilly and BioMS also announced that they would discontinue ongoing clinical trials and review available ...

Repligen Reports First Quarter Fiscal Year 2010 Financial Results

...andomized, double-blind, placebo-controlled clinical trial in which approximately 150 patients with bipolar depression will receive either RG2417 or a placebo twice a day for eight weeks. The study is designed to assess the safety and efficacy of RG2417 on the symptoms of depression as measured by the Montg...

GeoVax Labs, Inc. Provides Clinical Studies Update

...ingham, and Vanderbilt University, Nashville. The trial is still expected to include a total of 225 volunteers (150 vaccine recipients and 75 placebo recipients) and take place at 13 HVTN sites: 11 in North America and two in South America. Sites in the United States include Emory University, Atlant...

Shire plc: Core Portfolio of Products Delivers 20% Sales Growth

...line INTUNIV(TM) - for the treatment of ADHD in children and adolescents in the US. - On May 19, 2009 Shire announced that a randomized placebo controlled trial had met its primary objective, evaluating the effects of INTUNIV on oppositional symptoms in children aged 6 to 12 years ...

DOR BioPharma Receives FDA Orphan Drug Designation for orBec(R) for the Treatment of Chronic Gastrointestinal GVHD

...8%) deaths in the orBec(R) group compared to 16 patient (24%) deaths in the placebo group (p-value 0.0139). At one year post randomization in the Phase 3 trial, 18 patients (29%) in the orBec(R) group and 28 patients (42%) in the placebo group died within one year of randomization (46% reduction in mortality, p=...

Biotech Hot in July Driven by Positive Drug Data and Acquisitions

... symptoms of major depressive disorder for patients who did not respond to an older drug, Forest Laboratories Inc.'s Celexa. TC-5214 was better than a placebo at improving an overall depression measurement, as well as reducing depression, irritability and severity of illness, and leading to better cognition ...

Placebo in Biological Definition

Cancer

...nvestigate whether men taking daily selenium or vitamin E or both experience a reduced incidence of prostate cancer in comparison to men taking placebo pills. Daily use of tamoxifen , a selective estrogen receptor modulator, for up to 5 years, has been demonstrated to reduce the risk of developi...

Drug

...ct (user or patient) the user's expectations or beliefs about the drug ( placebo effect ) Distribution Two patterns of distribution, licensed and ...gal drug trade Route of administration 1971 Misuse of Drugs Act placebo effect Prohibition (drugs) Recreational drug use Responsible dr...