PinPoint

While on trail of dioxin, scientists pinpoint cancer target of green tea

Green tea appears to protect against cancer by affecting a "promiscuous" protein that pharmaceutical experts are already targeting in an effort to develop a new drug to stop the disease, scientists at the University of Rochester Medical Center have found. The research, which buttresses beliefs about the health benefits of green tea with solid scientific evidence, has been cited as part of the bes...

Pinpointing the cause of a neurodegenerative disorder

New understanding of spinocerebellar ataxiaResearchers have discovered how the abnormal repetition of a genetic sequence can have disastrous consequences that lead to the death of neurons that govern balance and motor coordination. The studies bolster the emerging theory that neurodegenerative disorders can be caused by having extra copies of a normal protein, not just a mutated one. Peopl...

Pinpointing a culprit molecule in Alzheimer's disease

One puzzle in Alzheimer's disease (AD) research is why mice engineered to have the abnormal protein underlying the disease in humans show little pathology of the disease. Specifically, such mice are genetically altered to overproduce mutant human amyloid precursor protein (APP). It is this protein that, when clipped by enzymes, produces the amyloid beta (Ab) peptide that clusters into the amyloid...

Scientists pinpoint inflammation gene

Discovery has implications for wide range of diseases A team of international researchers has discovered that a specific gene on chromosome 15 regulates inflammation, a finding with implications for a wide range of disorders, including cancer, cardiovascular disease, diabetes, obesity, Alzheimer's, and infections. The findings are published in the October 9 online issue of Nature Genetic...

New study pinpoints epicenters of Earth's imminent extinctions

Safeguarding 595 sites around the world would help stave off an imminent global extinction crisis, according to new research published today in the Proceedings of the National Academy of Sciences ( Conducted by scientists working with the 52 member organizations of the Alliance for Zero Extinction (AZE –?<A HREF="http://www.zeroextinction.org...

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PinPoint™ Vector Sequencing Primer from Promega

Description:The PinPoint™ Vector Sequencing Primer is designed for sequencing inserts cloned into the PinPoint™ Xa Vectors (Cat.# V2031, V2051, V2061). The primer hybridizes upstream of the Factor Xa site at nucleotides 325343, approximately 4050 base pairs upstream of the multiple cloning region and can be used to determine if an insert is cloned in-frame with the biotinylation purification tag...
Company:Promega

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Wisconsin doctors pinpoint cancer with TomoTherapy radiation treatment

announced last week that its Hi-Art System, a pinpoint radiation treatment, is being used in 20 institutions in North America, including <a href="http://www.froedte...

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Computer Tool Helps Pinpoint Risky Gene Mutations

Certain cancer risks can be passed down through families, the result of tiny changes in a family’s genetic code. But not all genetic// changes are deadly. To help medical counselors and physicians identify the mutations that pose the greatest health risks, researchers at four institutions, including Johns Hopkins, have developed and validated a new computer tool. The system, described...

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