FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
As any dedicated video game player knows, the first requireme...World's largest rainforest drying experiment completes first phase
Scientists with The Woods Hole Research Center are analyzing the surprising results of the first phase of a drydown experiment occurring in the Amazonian rainforest. From January 2000 to July 2004, rainfall was excluded from a one-hectare (2.2 acre) plot in the middle of the Tapajós National Forest, in Brazil. A total of 6 feet of rainfall was diverted with six thousand 2' by 6' clear plas...Eisai announces Phase II data on E7389, a potential new therapy for the treatment of breast cancer
Researchers today presented preliminary safety and efficacy data for E7389 in the treatment of advanced, refractory breast cancer during the San Antonio Breast Cancer Symposium. E7389 is a synthetic analog of halichondrin B (HB), which is a natural product shown in preclinical studies to have highly potent anti-cancer activity in vitro and in vivo. Halichondrin B was originally isolated from a t...Anti-Cyclin D2 (G1-phase Cyclin) Ab-2 Monoclonal Antibody, Unconjugated from Lab Vision
Description:Cyclin D2 is a G1 cyclin required for G1-phase progression and is a strong candidate for a proto-oncogene. cyclin D2 can phosphorylate pRB when associated with cdk4 and/or cdk6. NeoMarkers DCS-3.1 MAb is particularly well suited for neutralization of cyclin D2 activity in vivo....SPE (Solid Phase Extraction) from Tecan
Description:Solid phase extraction through columns is a well-known separation technique in a wide range of applications. Typical applications are in DNA/RNA extraction in microbiology, viral RNA isolation in diagnostics, or compound purification in chemical or analytical laboratories. This has been fully automated on the Genesis series instruments for smaller scales. The extraction is usually perform...Anti-Sheep/Goat Sac-Cel - Solid-phase Separation System from IDS Ltd
Description:Sac-Cel (Second Antibody Coated CELlulose) was developed in the late 1960s by Wellcome Diagnostics of Dartford, Kent, one of the earliest commercial pioneers of immunoassay in the world. IDS acquired the product range in 1987. Sac-Cel rapidly found favour with researchers and clinical biochemists developing their own "in house" radioimmunoassays, and became a benchmark methodology for the separat...Protocol for RNA Isolation Using TRIzol Reagent with Phase Lock Gel-Heavy
Phase Lock Gel may be used in conjunction with TRIzol Reagent for the isolation of total RNA from cell and tissue samples. Increased yields are observed using this method, because the entire aqueous phase can be recovered without interphase contamination. Below is a protocol outlining the steps involved in RNA...Protocol for RNA Isolation Using TRIzol Reagent with Phase Lock Gel-Heavy
Phase Lock Gel may be used in conjunction with TRIzol Reagent for the isolation of total RNA from cell and tissue samples. Increased yields are observed using this method, because the entire aqueous phase can be recovered without interphase contamination. Below is a protocol outlining the steps involved in RNA...Easy preparation of total RNA from cultured cells with TRIzol and Eppendorf Phase Lock Gel
Christian Bauer, Oliver Klotzsche, CCS Cell Culture Service GmbH, Falkenried 88, D-20251 Hamburg, Germany, Frank Apostel, Eppendorf AG, Germany The classic RNA isolation procedures are...Direct Monitoring of Solid-Phase Peptide Synthesis by MALDI-TOF MS
Mass spectrometry has proven to be a valuable tool in verifying and improving peptide synthesis. Matrix Assisted Laser Desorption Ionization (MALDI) Time-of-Flight (TOF) MS is particularly useful in that it is rapid, easy to use and requires relatively little maintenance. This work shows the ability of MALDI-TOF MS to follow the progress of sol...FDA approves Phase 0 trial which tests experimental drugs on humans
Good news for researchers has FDA has approved testing of small quantities of experimental drugs in human beings. Approval of small quantity drug clinical trial will be very helpful for researchers to// understand the path of the drug in the body and its efficacy if the drug is proved effective in small quantities researchers can proceed with a phase I clinical trial. Researchers feel...SARS-Free Taiwan to Mark End Phase of Global Fight
The WHO said on Friday it expected to announce the removal of the island from what was once a long list of infected regions or countries where new cases of the deadly virus had been reported within the previous 20 days. The normal incubation period for the disease is 10 days, and twice that time is the mandatory transmission-free period before //the WHO can declare a local emergency situati...S. Africa AIDS in 'death phase'
The AIDS epidemic in South Africa is entering the "death" phase as mortality outstrips new infections, say scientists."South Africa is experiencing a devastating epidemic -- the world's worst -- and this is just the beginning,'' said researchers . South African President Thabo Mbeki's government has been criticized for its lackluster approach to tackling the disease, //which has already in...Spray on contraceptive clears Phase I trial
An Australian drug delivery company called Acrux specializes in administering medicines// through the skin. It has recently reported positive results for its Phase I clinical results of a contraceptive for women in the form of a spray. The novel contraceptive spray called Nestorone MDTS is being developed in collaboration with a US-based research group 'The Population Council'. Interes...Phase 3 trials of two multi-kinase inhibitors against cancer
Sorafenib and stutent multi-kinase inhibitors against cancer is undergoing phase 3 trials// and these two drugs gained more appreciation in this years ASCO (American Society of Clinical Oncology) conference. This drug is gaining interest due to its multiple mechanism of action – known as Multi-kinase inhibitors. These drugs are in trial against different types of cancer and are found to be very e...Quantaphase II RBC Folate Reagent Pack
Description:Bio-Rad isotopic anemia assays feature standardized protocols and minimal pipetting steps for greater efficiency. Clear information about the processes involved in isotopic testing and the benefit to your laboratory is available from our customer support specialists....Bio-Phase II 3.0mm Suture Anchor
Description:LactoSorb copolymer is an absorbable co-polymer synthesized from all-natural ingredients: 82% L-Lactic acid and 18% glycolic acid. Unlike the homopolymers in common use such as 100% poly-L-lactic acid (PLLA) or 100% poly-glycolic acid (PGA), LactoSorb copolymer is substantially amorphous (without crystallinity), meaning that its degradation is uniform, precluding the crystalline release associate...Data Available From Erbitux Phase III Study in First-Line Treatment of Advanced Lung Cancer
NEW YORK, July 12, 2007 /PRNewswire-FirstCall/ -- ImCloneSystems Incorporated and Bristol-Myers Squibb Company todayannounced results from an open-label Phase III study of ERBITUX(R)(Cetuximab) plus a taxane and carboplatin in the first-linetreatment for metastatic non-small cell lung cancer (NSCLC). Thestudy did not meet its primary endpoint of progression-freesurvival (PFS) as assessed...Manhattan Pharmaceuticals Announces Results of Phase 2a Studies for Oral Oleoyl-estrone
- Results Fail to Demonstrate Meaningful Placebo Adjusted WeightLoss; Obesity Program to be Discontinued NEW YORK, July 09, 2007 /PRNewswire-FirstCall/ -- ManhattanPharmaceuticals, Inc. today announced results of the company's twoPhase 2a clinical trials of oral Oleoyl-estrone (OE). The resultsof both randomized, double-blind, placebo-controlled studies, onein common obesity and the other...