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pharmacological in Medical News

GeneGo Awarded NIH Grant to Develop Pharmacogenomics Software Suite

...ion resequencing projects are already generating vast amounts of data on genetic factors contributing to disease susceptibility and variability in the pharmacological and toxicological effects of drugs," said Richard Brennan, Director of Toxicology at GeneGo and PI on the grant. "What is lacking are powerful tools f...

Zucker Hillside Researchers to Receive Large Federal Grant to Test for the Early Treatment of Schizophrenia

...llside/Feinstein scientists and another at Columbia University’s New York State Psychiatric Institute. The interventions include the latest pharmacological and psychosocial treatments; the study design includes doctors, patients, families and scientists who will weigh in on the interventions to identify w...

Study finds citrus-derived flavonoid prevents obesity

...e concentrations of the citrus-derived flavonoid being studied are at higher levels than you could get from dietary components. "We are examining the pharmacological properties of naringenin," explains Huff. "The next step is to find out if naringenin prevents heart disease in animal models and to explore the feas...

New Cases of Alzheimer's and Dementia Continue to Rise, Even in the 'Oldest Old'

...entia Risk Continues to Rise in the "Oldest Old" Ugo Lucca, head of the Laboratory of Geriatric Neuropsychiatry at the Mario Negri Institute for pharmacological Research in Milano, Italy, and colleagues conducted a prospective, door-to-door, population-based study of all people age 80 years or older in eight m...

New cases of Alzheimer's and dementia continue to rise, even in the 'oldest old'

... Dementia Risk Continues to Rise in the "Oldest Old" Ugo Lucca, head of the Laboratory of Geriatric Neuropsychiatry at the Mario Negri Institute for pharmacological Research in Milano, Italy, and colleagues conducted a prospective, door-to-door, population-based study of all people age 80 years or older in eight m...

Portola Pharmaceuticals Announces Several Scientific Presentations at International Society on Thrombosis and Haemostasis XII Congress

... Date: Monday, July 13, 12:30-2:15 p.m. Location: Poster Area, Platelet Biology New Directions in Antithrombotic Drug Discovery: pharmacological Uncoupling of Arterial thrombosis from Hemostasis (Presentation #AS-TU-026) Presenter: David Phillips Date: Tuesday, July 14, 1:15-1:45 p...

Inflammation may trigger Alzheimer's disease, Saint Louis University findings suggest

...disease, says a Saint Louis University doctor and researcher. Two research studies published by William A. Banks, M.D., professor of geriatrics and pharmacological and physiological science at Saint Louis University School of Medicine, support this conclusion and offer what he calls a "one-two punch" in giving cl...

Even Steroid-Free Bodybuilders Focus on Image

...natural and non-natural bodybuilders, I found that either group is equally likely to have all of the traits of muscle dysmorphia with the exception of pharmacological use." More information The National Eating Disorders Association offers ways for males to boost body image . -- R...

Ready for relapse: Molecule helps breast cancer cells to survive in the bone marrow

...tastasis latency, and suggests strategies to hasten the attrition of disseminated breast cancer cells," concludes Dr. Massague. "Recently, a number of pharmacological Src inhibitors have been developed that may be worthy of consideration in this respect." ...

National Expert on Prescription Drug Abuse, Addicted Physicians Available for Media Interviews From Hazelden

...onals who have easy access to prescription medicines. Dr. Seppala, a graduate of Mayo Medical School, is well-regarded for his ground-breaking work in pharmacological studies and evidence-based systems in addiction treatment. Dr. Seppala has appeared as a guest on the CBS-TV "Early Show" and National Public Ra...
pharmacological in Medical Technology

MAP Pharmaceuticals Reports Positive Pharmacological Response Data for Migraine Product Candidate at the American Headache Society Annual Meeting

MOUNTAIN VIEW, Calif., June 28 /PRNewswire-FirstCall/ -- MAP Pharmaceuticals, Inc. (Nasdaq: MAPP ) today presented data from an in-vitro study evaluating receptor pharmacology of MAP0004, orally inhaled dihydroergotamine (DHE) for the potential treatment of migraine, compared to intravenous (...

Isis Reports Strong Financial Results and Highlights for Second Quarter of 2009

...ated to revenue from its collaboration with GSK, including the $500,000 discovery milestone payment that Regulus received from GSK for demonstrating a pharmacological effect in immune cells by specific microRNA inhibition. Excluding non-cash compensation expense related to stock options, operating expenses fo...

Michael J. Fox Foundation Awards Over $2 Million for Validation of 10 Parkinson's Therapeutic Targets

... The therapeutic role of CMA-MEF2D in the survival of dopamine neurons Zixu Mao, PhD, Emory University SHP-2 phosphatase: A new pharmacological target for Parkinson ' s disease? Maria-Cristina Missale, PhD, University of Brescia (Italy) Validation of Nurr1 as a Drug Target for...

Amicus Therapeutics Commences Phase 3 Trial Evaluating Amigal(TM) for the Treatment of Fabry Disease

...f Shire plc, to jointly develop Amicus' three lead pharmacological chaperone compounds for lysosomal storage disorder...mpany developing novel, oral therapeutics known as pharmacological chaperones for the treatment of a range of human genetic diseases. pharmacological chaperone technology involves the use of small mol...

Lilly Announces Positive Phase II Data on Investigational Medicine for Patients with Type 2 Diabetes

...f a dipeptidyl peptidase-IV (DDP-IV) protected GLP-1 analog linked to a fragment of immunoglobulin G4 that is believed to increase the duration of its pharmacological effect. Based on this study presented at this year's ADA meeting, LY2189265 is believed to reduce blood sugar in patients with type 2 diabetes by enh...

PARI Pharma Reports Successful Phase Ib Clinical Results for Inhaled Liposomal Cyclosporine A and Gains FDA Orphan Drug Designation for the Prevention and Treatment of Bronchiolitis Obliterans

...t PARI Pharma's Inhaled L-CsA Formulation PARI Pharma's L-CsA is a low-dose, inhaled, liposomal cyclosporine A formulation that aims to improve the pharmacological profile, the highly variable bioavailability, and the severe side effects of oral CsA. (Severe side effects of oral CsA include kidney and brain dama...

Metabolic Solutions Development Company Announces Preliminary Results from Phase IIa Clinical Trial

...etabolic Solutions Development Company ( www.msdrx.com ), based in Kalamazoo, Mich., is developing innovative therapeutics using a different pharmacological path to treat type 2 diabetes . This new approach seeks to improve the efficacy of treatment by freeing patients from the adverse side effects of cur...

One Step Closer: Novel Opioid Receptor Compound in Phase I Clinical Trials

...he company, initiation of the phase 1 trial of ALKS 33 was based on the compound's potential for a superior pharmacokinetic profile and the compound's pharmacological properties relative to other commercial opioid antagonists. According to Alkermes, data from the phase 1 study of ALKS 33 showed that the compou...

Paloma Pharmaceuticals Presents at the Association for Research in Vision and Ophthalmology 2009 Meeting

...tinue at low levels even after the retina is reattached. While there have been numerous attempts to reduce the incidence of PVR, to date no effective pharmacological treatment has been found. About the PI3K/Akt/mTOR Pathway and Palomid 529 The PI3K/Akt/mTOR pathway has been implicated in a wide variety of ...

Amicus Therapeutics Announces Issuance of New Plicera(TM) Composition of Matter Patent

...rty portfolio for our development programs and our pharmacological chaperone technology platform." Plicera is cu...c, to develop and commercialize Amicus' three lead pharmacological chaperone compounds for lysosomal storage disorder...mpany developing novel, oral therapeutics known as pharmacological chaperones for the treatment of a range of human g...
pharmacological in Medical Products

Angiotensin II

Description:... The determination of Ang II is a helpful tool in monitoring the pharmacological effect and efficiency of a wide variety of angiotensin converting enzyme inhibitors (ACE Inhibitors) or Angiotensin II receptor antagonists as well as...
Company:Buhlmann Laboratories AG

Tango Exercise Stress BP Monitor

Description:...our patient's systolic and diastolic BP along with heart rate. It's a Blood Pressure monitor designed specifically for use in treadmill, ergometer and pharmacological stress test environments. Tango is also ideal for use in research environments. Tango excels where other BP monitors have failed by making use ...
Company:SunTech Medical

A to Z Drug Facts

Features:... A2zDrugs™ allows the practitioner to refer to accurate information about pharmacological issues at point of care and contains information on over 700 generic and 2,800 trade name drugs With Skyscape's patented smARTlink™ technology,...
Company:Skyscape, Inc.

Healon 5 (viscoadaptive)

Features:...ressure to aid wound contruction Healon5 also can be used to efficiently separate and control ocular tissues Healon5 is not designed to have any pharmacological effect ...
Company:Advanced Medical Optics, Inc.
pharmacological in Medical Definition

Depolarization-induced suppression of inhibition

... vanilloid transient receptor potential vanilloid type 1 receptors in the mouse brain. Neuroscience. Apr 5; In Press. Hajos N, Freund TF. (2002) pharmacological separation of cannabinoid sensitive receptors on hippocampal excitatory and inhibitory fibers. Neuropharmacology. Sep;43(4):503-10. Hajos N, Led...
pharmacological in Medical Dictionary

Ritalin

...ntion-deficit ... Ritalin in the SR tablets is more slowly but as extensively absorbed as in the ... Nicotine & Ritalin ... Ritalin has pharmacological effects similar to those of amphetamines and cocaine. Individuals abuse Ritalin for its stimulant effects, ... Learn more about Ritalin or m...

Pharmacology

...sely allied. ... This is the homepage for the Department of Pharmacology at the University of Virginia Health System ... Pharmacology Faculty. pharmacological Sciences Training ... Welcome to the Michigan State University Department of Pharmacology and Toxicology. Our goal is to provide the background ...

Kinins

... Latest research news and information about Kinins - A generic term used to describe a group of polypeptides with related chemical structures and pharmacological ... Vasoactive Peptides and NO flashcards, matching games, crossword, hangman and other study tools. ... kinins ... enzymes that metabolize k...

Erythropoietin

...the bone marrow to ... Erythropoietin . Feline Infectious Peritonitis. Feline Leukemia Virus. First Aid ... Erythropoietin . updated Feb 2005. pharmacological cheating in sports is not a ... Erythropoietin (pronounced, ah-rith-ro-poy-tin, and abbreviated, EPO) is a ... ...

Digoxin

...ign of digoxin toxicity. ... digoxin n. A cardiac glycoside, C 41 H 64 O 14 , obtained from the leaves of a foxglove, Digitalis lanata, with pharmacological effects similar to Learn how the drug digoxin can be used to treat heart disease. ... Digoxin is usually taken once a day, especially in t...

Caffeine

...t too much can be harmful. ... How much caffeine is in your daily habit? 10 tips for better sleep ... Believe it or not, caffeine has the same pharmacological effects on the body as ... Caffeine seems to affect the amount of time the baby spends resting, which could ... The International Food Informati...
pharmacological in Biological News

Neuropathic pain: The sea provides a new hope of relief

...have specific functions with low side effects. Moreover, we need better management for chronic pain conditions," says Dr Wen. "Today there are few pharmacological agents that can help people suffering from neuropathic pain, but we believe that these marine-derived compounds could lead to the development of a new...

UCLA researchers discover new molecular pathway for targeting cancer, disease

...ls within the cell, which is currently poorly understood. The next stage of the research will focus on activating the LXR pathway using various pharmacological molecules to inhibit tumor formation. Matsui will be a collaborator in this follow-up research. In addition, the team has started a medicinal c...

22nd Congress of the European College of Neuropsychopharmacology, Sept. 12-16, 2009, Turkey

...ap between basic research and medical practice, paving the way for improved pharmacological treatments in mental disorders. With the 22nd ECNP Congress 2009 in Istanbu...rugs, which act on specific receptors within a neurotransmitter system. The pharmacological progress achieved in recent decades is mainly due to the development of rec...

Discovery may provide new treatments for alcohol dependence

...s that block the receptors for ghrelin, we could have a new effective treatment for alcohol dependence. It may however take several years until such a pharmacological treatment will reach the patient", says Professor Emeritus Jrgen Engel, an authority on research on alcohol dependency at the Sahlgrenska Academy. The...

Fatty foods -- not empty stomach -- fire up hunger hormone

... and is found in the body in high concentrations just before meals. It is dubbed the "hunger hormone" because it has been shown that administration of pharmacological doses acts in the brain to stimulate hunger and increase food intake in animal models and humans. The ghrelin hormone is unique in that it requires...

REGiMMUNE presents enhanced efficacy data in preclinical transplantation models

...f calcineurin inhibitors that are not only associated with high toxicity but suppress Treg activity. The finding suggests the possibility to develop a pharmacological approach to induce long-term transplant tolerance by promoting the body's intrinsic tolerogenic pathways using RGI-2001. RGI-2001 is in late precli...

Adult bone marrow stem cells injected into skeletal muscle can repair heart tissue

...egimen, if validated clinically, is expected to facilitate future stem cell therapy for heart failure." Lee said the next step is to use genetic and pharmacological engineering to make the stem cells more active, so good therapeutic effects can be achieved with fewer cells. "That is our goal. It would reduce t...

Yale team identifies key to potential new treatment for allergy-induced asthma

...rthermore, when the Yale-Hydra team administered a pharmacological agent, HC-030031, that is known to inhibit pain re...and mucus overproduction," Jordt explained. The pharmacological agent observed in this study to diminish asthmatic...est in the potential development of HC-030031 as a pharmacological treatment. ...

American Chemical Society Weekly PressPac -- April 15, 2009

...ory rats of a wireless sensor that overcomes some of those drawbacks. The scientists used a variety of techniques including physiological stimuli and pharmacological treatments to raise or lower their brain oxygen levels. The simple sensor quickly and reliably recorded real-time changes in these oxygen levels and ...

Jefferson researcher awarded Landenberger Foundation grant for ALS research

... bioavailability and metabolism." said Dr. Pasinelli. "Proteins called multi-drug resistance transporters are increased during the disease, rendering pharmacological treatments for ALS mostly ineffective. This grant will support research towards finding ways to inactivate these transporter proteins to counteract t...
pharmacological in Biological Technology

Development of a sensitive enzyme fragment complementation assay for cyclic adenosine 3', 5' monophosphate and its validation for pharmacological screening at G protein-coupled receptors

Key words: cAMP • GPCR • enzyme fragment complementation • LEADseeker • assay miniaturization G protein-coupled receptors (GPCRs) are the largest family of transmembrane receptors and are responsible for the transduction of ...

Amicus Therapeutics Announces Second Quarter 2009 Financial Results

...f Shire plc, to jointly develop Amicus' three lead pharmacological chaperone compounds for lysosomal storage disorder...mpany developing novel, oral therapeutics known as pharmacological chaperones for the treatment of a range of human genetic diseases. pharmacological chaperone technology involves the use of small mol...

Ceregene Receives Additional Grant From Michael J. Fox Foundation to Expand Long-Term Testing of CERE-120 Patients

...g normal function. Neurturin is a member of the same protein family as glial cell-derived neurotrophic factor (GDNF). The two molecules have similar pharmacological properties, and both have been shown to benefit the midbrain dopamine neurons that degenerate in Parkinson's disease. Degeneration of these neurons i...

Amicus Therapeutics Announces Second Quarter 2009 Financial Results Release Date

...is a biopharmaceutical company developing novel, oral therapeutics known as pharmacological chaperones for the treatment of a range of human genetic diseases. pharmacological chaperone technology involves the use of small molecules that selectively b...

Histogen Hair Regrowth Clinical Trial Presented at ISHRS Annual Meeting

...ns suffering from hair loss. Of the 87 million people in the United States that suffer from hair loss, it is estimated that only 2-7% seek surgical or pharmacological treatment. The same is true internationally due to the general lack of effective medical options for this widespread condition. "Hair restora...

Supelco(R) and MIP Technologies Launch New SPE Product for the Selective Extraction of NSAIDs From Environmental Water

...ric acid is an active metabolite of clofibrate, etofibrate and etofyllinclofibrate. These compounds are used as blood lipid regulators. Because of the pharmacological activity of the NSAIDs and the possibility of entry into the domestic water cycle, the concentrations need to be accurately quantified in natural wate...

Santaris Pharma - Interim Report for the Period 1 January to 30 June 2009

...g cholesterol levels, have been selected for pharmacological studies. - The Collaboration with the Company...o high cholesterol. These candidates are ready for pharmacological studies. Collaborations Santaris Pha... and the PCSK9 lead candidates which are ready for pharmacological studies. See Santaris Pharma's pipeline thr...

Novel Product for the Prevention of Post-Surgical Adhesion Formation Completes Phase I Clinical Study

...drug PXL01 is safe and well tolerated. Initially developed to prevent post-surgical adhesion formation following hand surgery the product combines the pharmacological effect of PXL01 with the physical barrier effect of the vehicle, and has the potential to be the first anti-adhesion drug on the market. 'These result...

AEterna Zentaris: New Data Published on its Ghrelin Antagonist Compound, AEZS-123 (JMV2959), Supports its Use in Alcohol Addiction

... Locatelli. The research projects were targeting the chemical synthesis and pharmacological investigation of new compounds acting as ghrelin antagonists. In 2006, AEterna Zentaris reported first in vivo pharmacological data on the capability of proprietary ghrelin receptor antagonists to selec...

Celator(R) Pharmaceuticals Presents Data on the Activity of CPX-351 Against Leukemia at the European Hematology Association Congress

...f the European Hematology Association (EHA) in Berlin, Germany, June 4-7, 2009 (Abstracts 1398 and 383). "These findings underscore the potential pharmacological and pharmacokinetic advantages of CPX-351 in the treatment of advanced leukemias," said Scott Jackson, chief executive officer, Celator Pharmaceutical...
pharmacological in Biological Products

Human, Porcine Endothelin-1 from Biotrend Chemikalien GmbH

Description:...respectively. All three isopeptides produce strong in vitro vasoconstrictor and in vivo pressor responses. However, the quantitative profiles of their pharmacological activities vary greatly. Storage: Desiccate at -20 C...
Company:Biotrend Chemikalien GmbH

Neurobiology of Alzheimer's Disease from Promega

Description:...of beta-amyloid and tau proteins, the role of apolipoprotein E and the use of transgenic models. The neurochemistry, in particular potential areas for pharmacological intervention are also discussed....
Company:Promega

microPET Focus 120 from CTI Molecular Imaging, Inc.

Description:...rs around the world are using microPET scanners to Study animal models of human disease Study genetically engineered animals Assess new pharmacological agents in drug development Assess novel drug delivery and gene therapy approaches Develop new molecular imaging assays Develop new radi...
Company:CTI Molecular Imaging, Inc.

microPET R4 from CTI Molecular Imaging, Inc.

Description:...rs around the world are using microPET scanners to Study animal models of human disease Study genetically engineered animals Assess new pharmacological agents in drug development Assess novel drug delivery and gene therapy approaches Develop new molecular imaging assays Develop new radi...
Company:CTI Molecular Imaging, Inc.

microPET Focus 220 from CTI Molecular Imaging, Inc.

Description:...rs around the world are using microPET scanners to Study animal models of human disease Study genetically engineered animals Assess new pharmacological agents in drug development Assess novel drug delivery and gene therapy approaches Develop new molecular imaging assays Develop new radi...
Company:CTI Molecular Imaging, Inc.

Rabbit Anti-Human PHAS-II Polyclonal Antibody, Unconjugated from Lab Vision

Description:...4E complexes. This allows eIF-4E to bind to eIF-4G (p220), thereby increasing the amount of the eIF-4F complex and the rate of translation initiation. pharmacological and genetic evidence indicates that the mTOR/p70S6K pathway is involved in the control of PHAS-I and -II. Thus, PHAS proteins may be mediators of the ...
Company:Lab Vision
pharmacological in Biological Dictionary

Polysaccharides

...arbohydrates. ... Lycium Barbarum (Goji) Polysaccharide Research - Zhongguo Zhong Yao Za Zhi. ... Lycium barbarum polysaccharides have the best pharmacological effect when it was ... Polysaccharides synonyms, Polysaccharides antonyms. Information about Polysaccharides in the ... of glucose that is ...

Helicase

...our genes. ... DNA Helicase - Unzip Your Genes. Shopkeeper: Name: Jim Dandy's Haberdashery. View ... Helicase inhibitors represent a class of pharmacological agents useful for the ... Runyon et al., Eischerichia coli helicase II (UvrD) protein initiates DNA ... The helicase and ATPase activities re...

Alkylating agents

... Alkylating Agents . Central Nervous System Depressants. Ethanol ... Polyfunctional alkylating agents . Mechanism of Action. Drug Resistance. pharmacological Effects ... Alkylating Agent Toxicity: Summary ... ... M. Membranous nephropathy: role of alkylating agents . Nephrology 2006 Apr;11(S1) ......
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Breaking Medicine News(10 mins):Health News:A Florida Jury Awards Widow More Than $23 Billion in Punitive Damages in a Lawsuit Brought Against Tobacco Maker, R.J. Reynolds, Parker Waichman LLP Comments 2Health News:A Florida Jury Awards Widow More Than $23 Billion in Punitive Damages in a Lawsuit Brought Against Tobacco Maker, R.J. Reynolds, Parker Waichman LLP Comments 3Health News:Hastings and Hastings Announces Complimentary Consultation Services 2Health News:Hastings and Hastings Announces Complimentary Consultation Services 3Health News:Rhymes Reveal Evidence of Learning in the Womb 2Health News:ASA launches national Perioperative Surgical Home learning collaborative 2Health News:ASA launches national Perioperative Surgical Home learning collaborative 3Health News:Dr. Boylan Joins CarePoint Health Medical Group 2
(Date:7/24/2014)... at Albert Einstein College of Medicine of ... J. Fox Foundation for Parkinson,s Research to translate a ... This drug discovery project will test chemical compounds on ... a drug that acts on an underlying cause of ... help many people manage their symptoms, we are eager ...
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Breaking Biology News(10 mins):Albert Einstein College of Medicine receives grant from the Michael J. Fox Foundation to fund drug discovery project targeting Parkinson's 2Albert Einstein College of Medicine receives grant from the Michael J. Fox Foundation to fund drug discovery project targeting Parkinson's 3Experts Weigh the Pros and Cons of a $1.7 Billion EPA Cleanup Plan for the Passaic River at an NJIT 2Whitehead Institute researchers create 'naïve' pluripotent human embryonic stem cells 2
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