Phage

Basis for DNA ejection from single phage particles

Studying phage, a primitive class of virus that infects bacteria by injecting its genomic DNA into host cells, researchers have gained insight into the driving force behind this poorly understood injection process, which has been proposed in the past to occur through the release of pressure accumulated within the viral particle itself. Almost all phages (also known as bacteriophages) are f...

UCSB researchers discover shape matters to macrophages

Researchers at UC Santa Barbara have made a surprising discovery: phagocytosis depends more on particle shape than size. The research, which has far-reaching implications for immunology, vaccine development and drug delivery, is published today online in the Proceedings of the National Academy of Sciences by Samir Mitragotri, a UCSB professor of chemical engineering, and graduate student Julie A....

Macrophage signaling may affect hormone resistance in prostate tumors

Interaction between prostate cancer cells and immune cells called macrophages may be a source of inflammatory signals capable of impacting the effectiveness of androgen antagonists, the most common and effective treatment for prostate cancer, according to a new study by researchers at the University of California, San Diego (UCSD) School of Medicine. Male hormones called androgens are es...

Pitt phage hunter takes on tuberculosis

One third of the world's people are infected with tuberculosis, and someone new is infected every second. TB is notoriously hard to treat, requiring a course of multiple antibiotics over six to nine months. Many people don't complete the full course of treatment, which leads to increasing antibiotic resistance against the disease. More effective treatments could be on the way, however, wi...

The connector rotation hypothesis? Phage do not pack their DNA by rotation

The life cycles of many viruses include a self-assembly stage in which a powerful molecular motor must pack the DNA genome into the virus's preformed shell (the capsid). How it manages this intricate feat has been subject to debate, but we know that the DNA passes into the capsid shell through a channel formed by a structure called the connector. Scientists have speculated that rotation of the co...

Phage at Biology Products

PhageMaker System from Novagen

Description:Novagens PhageMaker System is optimized for maximum packaging efficiencies of cDNA and genomic DNA inserts ligated with any bacteriophage l vector. Using a test insert with Novagen's l vector arms, efficiencies > 10^7 pfu/g arms (> 4 x 10^8 pfu/g ligated l control DNA) are typically obtained. This one-tube system is extremely easy to use; simply add up to 5 g of ligated vector plus insert to the...
Company:Novagen

Mouse Anti-Macrophage L1 protein Calprotectin Monoclonal Antibody, Unconjugated, Clone B314.1 (MAC 387) from Abcam

Description:Mouse monoclonal [B314.1 (MAC 387)] to Macrophage L1 protein Calprotectin (rating: ****) ( for all tested applications)....
Company:Abcam

Phage Display cDNA Library Screening Kit from Spring Bioscience

Description:Spring offers a large collection of phage display libraries, human adult tissues, fetal tissuea, cell lines, and mouse tissues. All cDNA libraries are constructed in pHD9 vector. The size of cDNA inserts has been verified to be from 200bp to 1000bp by gel electrophoresis of DNA prepared from the amplified libraries....
Company:Spring Bioscience

T7 Phage Capture Plate from Novagen

Description:The T7 Phage Capture Plate is a 96-well ELISA-compatible plate (containing 12 x 8-well strips) on which the T7 Tail Fiber Monoclonal Antibody is immobilized by a method that retains maximal binding activity. The antibody specifically recognizes the tail fiber protein of the T7 bacteriophage. This 8-well strip plate has a capacity of 10 phage per well and low non-specific binding. Phag...
Company:Novagen

Zero Blunt TOPO Kit for Sequencing with One Shot Mach1 T1 Phage-Resistant Chemically Competent E. coli from Invitrogen

Description:The TOPO Cloning Kits for Sequencing allow 5-minute cloning and subsequent sequencing of PCR products. The kits contain TOPO Cloning vectors with primer sites located as close as 33 base pairs from the PCR product insertion site. This minimizes the amount of vector DNA that needs to be read before reaching the sequence of your insert.vectors are available. The pCR4-TOPO vector provides 3-T overha...
Company:Invitrogen

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Phage at Biology Technology

M13/Phagemid DNA Extraction Protocol

Efficiency of the standard protocols for production of single-stranded DNA may be improved through the use of PLG. For producing M13 ssDNA, mix 2.5 ml plating bacteria (57...

M13/Phagemid DNA Extraction Protocol

Efficiency of the standard protocols for production of single-stranded DNA may be improved through the use of PLG. For producing M13 ssDNA, mix 2.5 ml plating bacteria (57...

Laser Capture Microdissection (LCM) for the Analysis of Macrophage Gene Expression from Atherosclerotic Lesions

Macrophage foam cells are integral in the development of atherosclerotic lesions, however gene expression studies are complicated by the cellular heterogeneity of atherosclerotic plaque. This application note describes a protocol for LCM of cells identified immunohistochemi...

Phage at Biology Definition

Prophage

A . When stress in the host is detected...

Phage

. Like viruses that infect <a href="/ ?q=/ Biology-De...

Lambda phage

, it may integrate itself into the host's <a href="/ ?q=/ Biolog...

Phage at Biology Dictionary

Prophage

A of a bacterium....

Phagemid

phage<...

Phage

A integrated into the <a href="/ ?q=/ Bio...

Lambda phage

The life cycle of formed into the <a href="/ ?q=/ Biology-Diction...

Bacteriophages

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Phage at Medicine News

Improved procedure to do laproscopic esophagectomy discovered

Researchers have developed a new improved procedure to do laproscopic esophagectomy on patients who suffers// from the problems of esophagus, including cancer of the esophagus. Currently to test the extent of damage in the esophagus, surgeons had accepted a noninvasive procedure called laproscopic esophagectomy. In this process the surgeons had to make a small incision on the abdomen o...

Lymph Cell Growth In Eyes Related To Macrophages

Researchers from Harvard Medical School had discovered a kind of immune cells called macrophages are behind the growth of new lymph vessels in the eyes. These new lymph vessels help in healing of the eyes in case of there being any wounds. // The discovery of this new role for the macrophage, published in the September 2005 Journal of Clinical Investigation, may ultimately inspire inn...

Macrophage Inhibitory Factor Causes Multiple Sclerosis Progression

Researchers have found that Migration/Macrophage Inhibitory factor (MIF) which is an immune cell responsible for progression of Multiple Sclerosis. This new pathway can be used in finding drugs which reduces the amount of MIF // in a way progression of Multiple Sclerosis is hindered. Multiple Sclerosis is an autoimmune disease which is caused by non-...

Soft Drinks May Reduce Esophageal Cancer Risk

A study conducted by the researchers from the Yale School of Medicine has revealed that diet soda drinkers run a decreased risk of contracting cancer//. Until recently it was believed that there was a 350% higher risk of getting esophageal cancer through consuming carbonated soft drinks. In their study published in the recent of Journal of the National Cancer Institute (JNCI), the researchers rep...

PET Can Predict Response To Treatment In Esophageal Cancer Patients

Positron Emission Tomography (PET) is more accurate than traditional radiological methods in predicting the patients' response to chemotherapy// and radiation, says new research at Wake Forest University Baptist Medical Center. The findings of the study are published in the April issue of Annals of Surgery. The researchers examined 64 patients with esophageal cancer with PET, which shows...

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Phage at Medicine Products

Combitube® Esophageal/Tracheal Double-Lumen Airway

Description:Rapid intubation of difficult airways. When a difficult airway must be established, time and accuracy are critical. Now you can be assured of rapid intubation and effective ventilation with the Combitube®: Esophageal/Tracheal double-Lumen Airway from Nellcor. Unlike traditional endotracheal tubes, the Combitube airway is designed to establish a nonsurgical patient airway when placed i...
Company:Nellcor

400 Series/Regular Tube Esophageal Stethoscope

Description:The pause of a heartbeat. The bodys warmth beneath drapes. The life-giving force of rhythmic breathing. These vital signs are yours to guard, measure, stabilize and cross check. DeRoyals line of Temperature Monitoring products helps you do your job, giving you the information needed to provide the most comfortable and precise management of your patients stability during surgical procedures. These...
Company:DeRoyal

Esophageal Stethoscope

Description:The pause of a heartbeat. The bodys warmth beneath drapes. The life-giving force of rhythmic breathing. These vital signs are yours to guard, measure, stabilize and cross check. DeRoyals line of Temperature Monitoring products helps you do your job, giving you the information needed to provide the most comfortable and precise management of your patients stability during surgical procedures. These...
Company:DeRoyal

400 Series/Extra-Long Length Esophageal Stethoscope

Description:The pause of a heartbeat. The bodys warmth beneath drapes. The life-giving force of rhythmic breathing. These vital signs are yours to guard, measure, stabilize and cross check. DeRoyals line of Temperature Monitoring products helps you do your job, giving you the information needed to provide the most comfortable and precise management of your patients stability during surgical procedures. These...
Company:DeRoyal

400 Series/Soft Tube Esophageal Stethoscope

Description:The pause of a heartbeat. The bodys warmth beneath drapes. The life-giving force of rhythmic breathing. These vital signs are yours to guard, measure, stabilize and cross check. DeRoyals line of Temperature Monitoring products helps you do your job, giving you the information needed to provide the most comfortable and precise management of your patients stability during surgical procedures. These...
Company:DeRoyal

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Phage at Medicine Technology

Phosphagenics Announces Positive Proof of Concept Results from Studies Utilizing Company's Dermal Drug Delivery Technology

MELBOURNE, Australia, June 25, 2007 /PRNewswire-FirstCall/ --Phosphagenics Limited (AIM: PSG) announced today positive resultsfrom pre-clinical studies of its TPM-02 dermal drug deliverytechnology formulated with retinoic acid, a leading topicaltreatment for severe acne and an active ingredient used inanti-aging cosmetics. The proof of concept studies showed a three-fold increase i...

NCCN Updates Esophageal and Gastric Cancer Guidelines

JENKINTOWN, Pa.--(BUSINESS WIRE)--May 22, 2007 - The NationalComprehensive Cancer Network (NCCN) announces updates to two NCCNClinical Practice Guidelines in Oncology(TM) -- Esophageal Cancerand Gastric Cancer. The NCCN Guidelines are updated continuously bypanels of world-renowned experts and are widely recognized andapplied as the standard of care in oncology in the United States inboth t...

FDA MedWatch: Avastin (bevacizumab) and Formation of Tracheoesophageal Fistula in a Recent Clinical Study in Patients with Limited-stage Small Cell Lung Cancer

ROCKVILLE, Md., April 21, 2007-Genentech and FDA notifiedhealthcare professionals of important new safety informationregarding tracheoesophageal (TE) fistula formation in a recentclinical study in patients with limited-stage small cell lungcancer (SCLC). This multicenter, non-randomized, single-arm phaseII clinical trial study combined chemotherapy and radiation plusAvastin. There have b...

DUSA Pharmaceuticals Receives Orphan Drug Desi gnation for Levulan PDT to Treat Esophage al Dysplasia

Researchers' Study Shows Promising Treatment for People Sufferingfrom Barrett's Esophagus, a Leading Cause of Esophageal Cancer WILMINGTON, MASSACHUSETTS--(CCNMatthews - May 17, 2007) - DUSAPharmaceuticals, Inc. (NASDAQ GM:DUSA) announced that the U.S. Foodand Drug Administration (FDA) has granted Orphan Drug Designationfor Levulan(R) (aminolevulinic acid HCl) Photodynamic Therapy (PDT)fo...

Oncophage Cancer Vaccine Significantly Prolongs Recurrence-Free Survival by 45 Percent in Patients With Intermediate-Risk Kidney Cancer

ANAHEIM, Calif.--(BUSINESS WIRE)--May 21, 2007 - Antigenics Inc.(NASDAQ: AGEN) today announced additional follow-up data on thecompany's Phase 3 investigational therapeutic cancer vaccineOncophage(R) (vitespen). The end-of-study results, which reflect anadditional 17 months' data collection, showed that in a substantialsubset of patients (n = 362) at intermediate risk for diseaserecurrence,...

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Phage at Medicine Dictionary

Macrophage

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Gastroesophageal reflux disease

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Esophageal stricture

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Esophageal cancer

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