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pestis in Medical News

Bacteria with a built-in thermometer

...urrent online edition of the PLoS Pathogens science magazine. Yersinia can trigger various different diseases: best well-known is the Yersinia pestis type which caused the Plague in medieval times. This led to the death of around a third of Europe's population. The Yersinia enterocolitica and Ye...

U.S. Department of Defense Exercises $2.0 Million Option to Fund Cethromycin Development

...ling studies to evaluate cethromycin's efficacy in combating Category A and B bioterror agents such as Fransicella tularensis (tularemia), Yersinia pestis (plague) and Burkholderia pseudomallei (melioidosis). Under the terms of the contract, $1.8 million of DoD funds were initially available to initia...

CSC's DynPort Vaccine Company to Continue Plague Vaccine Development

..., Md., and at various subcontractor sites. The rF1V plague vaccine candidate is designed to provide protection against the plague bacterium Yersinia pestis in aerosolized form. The vaccine was originally identified and developed by scientists working at the U.S. Army Medical Research Institute of Infectio...

Scientists look at 'syringe' assembly in plague bacteria

... previously identified sorting signals. The YscJ lipoprotein in Yersinia pestis is an essential part of the injection device, says Dr Plano. It serves as a...e systems. Understanding this mechanism tells us more about how Yersinia pestis causes plague. We now want to find out why the YscJ protein uses this unusu...

How Plague-Causing Bacteria Disarm Host Defense

...d be used in biological warfare, according to Navarro. The genus Yersinia includes three species of bacteria that are pathogenic to humans: Y. pestis is perhaps the most infamous, being responsible for the bubonic plague (also known as the Black Death), which killed more than 200 million people in t...

Scientists Find Potential Weakness In Plague Germ

...ss that could help make a particularly dangerous form easier to treat//, according to a study published on Thursday. A bacterium known as Yersinia pestis causes both bubonic plague, the dreaded Black Death spread when people are bitten by an infected flea, and pneumonic plague, spread from one person to...

Plague Proteome Reveals Proteins Linked to Infection

...likely proteins in the// plague-bacterium Yersinia pestis whose numbers rise and fall according to the disea... disrupt the microbe’s ability to infect. Y. pestis is the bacterium that caused the infamous Black De...This study mimicked environmental conditions of Y. pestis in flea and in mammalian systems. The proteo...

U.S. Scientists Discover Better Vaccination Method

...ate immune response of the host. Lien and his colleagues developed a Y. pestis strain with a coat that stimulates immune cells in mice, which showed that ...sults have suggested that immune stealth is probably critical for normal Y. pestis to cause serious infection. NLA ...

Tobacco plant based Vaccine against Plague

...n an increased threat of genetically modified resistant strains of Yersinia pestis produced as a bioweapon to cause bio terrorism. Scientists are not sure whe...uired strain of the bacterium and when challenged with a dosage of Yersinia pestis bacterium the guinea pig antibodies were found to counteract these bacteriu...
pestis in Biological News

New Systems Biology Awards enable detailed study of microbes

...telle-Pacific Northwest National Laboratory, Richland, WA Principal Investigator: Joshua N. Adkins, Ph.D. Focus: Salmonella enterica and Yersinia pestis Institute for Systems Biology, Seattle, WA Principal Investigator: Alan Aderem, Ph.D. Focus: Influenza virus, Staphylococcus aureus ...

UCF professor develops vaccine to protect against black plague bioterror attack

...e all orally immunized animals survived this challenge with no traces of the plague in their bodies. The rats were exposed to a heavy dose of Yersinia pestis bacteria, which causes the plague, at the U.S. Army Medical Research Institute of Infectious Diseases in Maryland. It is one of a few labs in the worl...

Scientists discover why plague is so lethal

...nal Microbiology. The plague bacterium Yersinia pestis needs calcium in order to grow at body temperature... of Chicago, USA. We found that this is because Y. pestis is missing an important enzyme. Bubonic plague ...ecular basis of its extraordinary virulence. Y. pestis evolved from its ancestor Y. pseudotuberculosis wi...

How plague-causing bacteria disarm host defense

...ld be used in biological warfare, according to Navarro. The genus Yersinia includes three species of bacteria that are pathogenic to humans: Y. pestis is perhaps the most infamous, being responsible for the bubonic plague (also known as the Black Death), which killed more than 200 million people in t...

Bacteria control how infectious they become, study finds

...infectious on or off. Knowing how disease-causing bacteria, like Yersinia pestis and E. coli, do this may one day help scientists create drugs that control ...ut it happens to turn on those genes that give bacteria like E. coli and Y. pestis their ability to infect. The researchers say that this study likely ma...

Will the plague pathogen become resistant to antibiotics?

...ic resistance could potentially spread to other Y. pestis and also other bacterial pathogens. In a paper pub... this study, the same MDR plasmids found in the Y. pestis from Madagascar were also present in bacteria such... found a plasmid usually found in Salmonella in Y. pestis is a big problem. It also raises a question about ...

Study illuminates how the plague bacteria causes disease

...n from the evolution of multidrug-resistant strains of the plague bacterium found in patients from several locations. The plague bacterium Yersinia pestis is closely related to Y. enterocolitica and Y. pseudotuberculosis, which are food-borne agents that cause inflammation of the stomach and intestines. ...

Caterpillars tell us how bacteria cause disease

...mmals they are equipped to deal with their immune system response and are able to spread rapidly. It is thought this is how bacteria, such as Yersinia pestis ?the cause of plague, could have evolved to wreak havoc in humans. Dr Nick Waterfield, who is leading the study, explained: "Bacteria have been ...

Plague proteome reveals proteins linked to infection

... likely proteins in the plague-bacterium Yersinia pestis whose numbers rise and fall according to the disea... disrupt the microbe’s ability to infect. Y. pestis is the bacterium that caused the infamous Black De...This study mimicked environmental conditions of Y. pestis in flea and in mammalian systems. The proteom...

New Look at DNA Hints at Origin of UV Damage

.... They also showed that the interaction between Y. pestis and the worm is quite similar to what occurs in ma... accelerate the process of better understanding Y. pestis pathogenesis. The shorter time and increased ease ...e researchers continued, given potential use of Y. pestis as a biological weapon, they said. The results ...
pestis in Biological Technology

Advanced Life Sciences' Restanza(TM) Shows 100% Survival In Confirmatory Anthrax Study

...nt in anthrax, Restanza is also being developed to combat other high priority bioterror agents such as Fransicella tularensis (tularemia) , Yersinia pestis (plague) and Burkholderia pseudomallei (melioidosis) under a two year, $3.8 million contract with the Defense Threat Reduction Agency (DTRA) of...

Tips from the journals of the American Society for Microbiology

...urnal Infection and Immunity . Transmitted by infected fleas, Yersinia pestis is the causative agent responsible for bubonic and pneumonic plague. Both ... The previously inoculated mice were then challenged intravenously with Y. pestis following which low levels of the bacteria were found in the organs and bl...

UCF professor develops vaccine to protect against black plague bioterror attack

...e all orally immunized animals survived this challenge with no traces of the plague in their bodies. The rats were exposed to a heavy dose of Yersinia pestis bacteria, which causes the plague, at the U.S. Army Medical Research Institute of Infectious Diseases in Maryland. It is one of a few labs in the worl...

Tips from the journals of the American Society for Microbiology

...urnal Infection and Immunity . Transmitted by infected fleas, Yersinia pestis is the causative agent responsible for bubonic and pneumonic plague. Both ... The previously inoculated mice were then challenged intravenously with Y. pestis following which low levels of the bacteria were found in the organs and bl...

UCF professor develops vaccine to protect against black plague bioterror attack

...e all orally immunized animals survived this challenge with no traces of the plague in their bodies. The rats were exposed to a heavy dose of Yersinia pestis bacteria, which causes the plague, at the U.S. Army Medical Research Institute of Infectious Diseases in Maryland. It is one of a few labs in the worl...

Tips from the journals of the American Society for Microbiology

...urnal Infection and Immunity . Transmitted by infected fleas, Yersinia pestis is the causative agent responsible for bubonic and pneumonic plague. Both ... The previously inoculated mice were then challenged intravenously with Y. pestis following which low levels of the bacteria were found in the organs and bl...

Advanced Life Sciences Awarded U.S. Department of Defense Biodefense Contract Valued at up to $3.8 Million

...enabling studies evaluating cethromycin's efficacy in combating Category A and B bioterror agents such as Fransicella tularensis (tularemia), Yersinia pestis (plague) and Burkholderia pseudomallei (melioidosis). (Logo: http://www.newscom.com/cgi-bin/prnh/20080218/ALSLOGO ) "We are very excited to partn...
pestis in Biological Products

Mouse Anti-Yersinia pestis Monoclonal Antibody, Unconjugated, Clone YPF19 from GeneTex

Description: Mouse monoclonal [YPF19] to Yersinia pestis This antibody is used to detect Yersinia pestis . Immunogen: Purified F1 antigen from Yersinia pestis vaccine strain EV76. Specificity: This antibody recognises Y.pestis F1 capsular antigen. There is no cross-reactivity with Y.pseudotuberculosis ...
Company:GeneTex

Mouse Anti-Yersinia pestis Monoclonal Antibody, Unconjugated, Clone YPF19 from Abcam

Description: Mouse monoclonal [YPF19] to Yersinia pestis ( Abpromise for all tested applications)....
Company:Abcam

Anti-Yersinia pestis Monoclonal Antibody, Unconjugated from ViroStat Inc.

Description: Yersinia pestis...
Company:ViroStat Inc.

Mouse Anti-Yersinia pestis Capsular F1 Antigen Monoclonal Antibody, Unconjugated, Clone YBF19 from QED Bioscience Inc.

Description: This monoclonal antibody specifically recognizes Y. pestiscapsular F1 antigen. It does not cross-react with Y. pseudotuberculosisor Y. enterocolitica....
Company:QED Bioscience Inc.

Mouse Anti-Yersinia pestis Capsular F1 Antigen Monoclonal Antibody, Unconjugated, Clone YBF19 from QED Bioscience Inc.

Description: This monoclonal antibody specifically recognizes Y. pestiscapsular F1 antigen. It does not cross-react with Y. pseudotuberculosisor Y. enterocolitica....
Company:QED Bioscience Inc.

Mouse Anti-Yersinia pestis F1 antigen Monoclonal Antibody, Unconjugated, Clone YPF19 from Abcam

Description: Mouse monoclonal [YPF19] to Yersinia pestis F1 antigen ( Abpromise for all tested applications)....
Company:Abcam

Mouse Anti-Yersinia pestis F1 antigen Monoclonal Antibody, Unconjugated, Clone YPF19 from Novus Biologicals

Description: Mouse anti-Yersinia pestis F1 antigen, Monoclonal Antibody, Unconjugated Applications: ELISA: Use at an assay dependent dilution. IF: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 18 kDa. Not tested in other applications. Optimal dilut...
Company:Novus Biologicals

Mouse Anti-Yersinia pestis F1 Antigen EB Strain Monoclonal Antibody, Unconjugated, Clone YPF19 from Meridian Life Science, Inc.

Description: MAb to Yersinia pestis F1 Ag. Yersinia pestis F1 Antigen EB Strain...
Company:Meridian Life Science, Inc.

Mouse Anti-Yersinia pestis F1 antigen Monoclonal Antibody, Unconjugated, Clone 1.F.1 from Abcam

Description: Mouse monoclonal [1.F.1] to Yersinia pestis F1 antigen ( Abpromise for all tested applications). Antigen: Purified F1 antigen of Y. pestis vaccine strain EB....
Company:Abcam

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pestis in Biological Dictionary

Sequence homology

...ology modeling, which worsen with lower sequence identity, derive ... ... italian poet, journal of bacteriology, sequence homology , yersinia pestis ... Most Emailed. sequence homology . Name. Address. City. State. Zip. Email ... BioInfoBank Library :: Sequence Homology :: Molecular chara...
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