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Chemists create 'Superbowl' molecule; May lead to better health

In a development that could one day score a touchdown for better health, chemists in Australia have created a "superbowl" molecule that shows promise for precision drug delivery, according to a recent study in the Journal of the American Chemical Society. Shaped like a miniature football stadium, the molecule is capable of delivering a wide range of drugs ?from painkillers to chemotherapy cocktai...

Poor prenatal nutrition permanently damages function of insulin-producing cells in the pancreas

Scientists at Joslin Diabetes Center have discovered one reason why infants with low birth weight have a high potential of developing type 2 diabetes later in life. In studies of mice, the researchers found that poor prenatal nutrition impairs the pancreas's ability to later secrete enough insulin in response to blood glucose. "The bottom line is that if you don't have delivery of enough...

Bound for destruction: Ubiquitination protects against improper Notch signaling

The is an important molecular signaling mechanism whose existence has beenknown, or at least hinted at, for nearly a century since theidentification of a mutant strain of Drosophila fruit flies with“notched?wings in Thomas Hunt Morgan’s lab in 1910. Later studiesrevealed that the Notch gene encodes a receptor protein tha...

Sea skate experiment sheds light on human cell transport

Along with Mark Musch, a longtime University of Chicago collaborator, Goldstein conducted an experiment with the red blood cells of skates to understand how these skinny, graceful fish can swim from salt water to fresh water. For humans, such a drastic environmental change would prompt an equally drastic physiological change: Our cells would take in too much water, diluting blood and other body f...

Experiments provide proof of how traveling in groups protects insects

Few events involving animals are more dramatic than when they band together and head out on the march cross-country. Among examples are the many thousands of wildebeests and other hoofed mammals that form herds and migrate across the African plains. and young locusts also sometimes unite with their...

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HybArray 12 DNA hybridization system from PerkinElmer

Description:The HybArray 12™ is an automated hybridization system for the processing of DNA microarrays. The system automates both the hybridization and post hybridization washing of microarrays spotted onto glass slides. A single instrument can process up to 12 slides at a time in pairs and has multi-protocol software, enabling the user to run all six modules with different protocols or all arrays und...
Company:PerkinElmer

PerkinElmer Spectrum Beer's Law QUANT Quantitative Software, CD from PerkinElmer

Description:A univariate (peak height or area) quantitative multi-component analysis package....
Company:PerkinElmer

PerkinElmer Spectrum Beer's Law QUANT Quantitative Software, Floppy Disk from PerkinElmer

Description:A univariate (peak height or area) quantitative multi-component analysis package....
Company:PerkinElmer

Rapidplate from Caliper Life Sciences

Description:The RapidPlate 96/384 workstation offers precise 96 and 384-well transfers in a small, highly scalable format. Utilizing 100ul and 200ul disposable tips, the 96 channel parallel pipetting head delivers excellent accuracy and precision across a volume range from 1-200uls. The six position rotary deck includes two positions that enable indexing into 384 well plates, and one position that can be fit...
Company:Caliper Life Sciences

LS 45 Luminescence Spectrometer, 120V from PerkinElmer

Description:The gold standard for automated bioresearch: Developed for a wide range of bioanalytical applications • Based on decades of experience in Luminescence Spectroscopy • Automated accessories designed for bioresearch • Holographic gratings for reduced stray light • Versatility, reliability and ease-of-use • Pulsed Xenon lamp reduces photo bleaching • Large convenient...
Company:PerkinElmer

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Effects of Thermal Cycler Well-To-Well Temperature Uniformity on PCR Results

Michelle Cayouette Jane Moores Jason Capodanno Michael Rahilly Stratagene produces consistent PCR results in every well. The RoboCycler systems uniquedesign uses thermal blo...

New Temperature Cycler Features Interchangeable Blocks

Michelle Cayouette Jane Moores Jason Capodanno Michael Steege Michael Rahilly Stratagene Infinitytemperature cycler, a new temperature cycler withinterchangeable blocks for...

Luminol-enhanced Assay for Superoxide Anion (O2 face="Symbol" )

Stratagene Dartmouth School of Medicine, Dept. of Microbiology, Hanover, NH</p...

Novel PCR Enhancing Factor Improves Performance of Pfu DNA Polymerase

pfuturbo DNA polymerase for robust, high-fidelity PCRamplification Holly Hogrefe Brad Scott Kirk Nielson ValerieHedden Connie Hansen Janice Cline Frances Bai Jeff Amberg RondaAllen Mark Madden Stratagene an improved version of Pf...

Comparing Fidelity and Performance of Proofreading PCR Enzymes

DNA polymerase is superior toPlatinum Stratagene Pfx DNA polymerase, a competitors new PCR enzyme formulationcon...

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Spermatogenesis

. Sperm cells develop initially from germ stem cells known as spermatogonia . As these differentiate th...

Spermatid

, each spermatid contains only half of the genetic material present i...

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core of the membrane, but attach indirectly, typically by bind...

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Bypass Heart Surgery Performed Without General Anesthesia

A minimally invasive direct coronary artery bypass (MIDCAB) procedure was performed at Pittsburgh while the patient was awake. The operation was done under thoracic epidural anesthesia. This approach may help in discharging the patient early from the hospital. Dr. Zenati from the team of doctors who performed the surgery said that patients who are operated in this way may not have to go t...

PRIMARY PULMONARY HYPERTENSION GENE DISCOVERED

The discovery of the gene associated with the inherited form of primary pulmonary hypertension (PPH) by Drs. Jane H. Morse of Columbia University and James A. Knowles of the Columbia Genome Center is indeed a major breakthrough. Their study, funded in part by the National Heart, Lung, and Blood Institute at the National Institutes of Health and published in the September issue of th...

Homeopathic preparation better than placebo in perennial allergic

A homeopathic preparation for perennial allergic rhinitis appears to be more effective than placebo. A multicenter team studied 50 patients with perennial allergic rhinitis. The subjects were randomized to receive either 30cc of a homeopathic preparation of principal inhalent allergen or placebo. In the third and fourth week after the start of treatment, the group compared changes in nasa...

Sperm washing helps couples – Breakthrough in focu

In many unfortunate instances we see couples who are HIV sero discordant but who would like to have a baby. If the husband is HIV –1 positive and the wife is negative and they are planning to have a child the problem arises because sexual intercourse carries a 1 in 500 risk of transmitting the virus to the female partner and through her to the fetus. Sperm washing is a risk-reduction opti...

Patient’s perception of health status helps in better recover

We always insist that we should feel healthy to actually live healthy. Doctors in England say that following a coronary bypass surgery; the patient’s attitude helps in an early recovery. To justify this argument the researchers conducted a health survey just before coronary bypass operations and assessed the patient’s own perception of his/her own health status. Following surgery those wh...

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Nagahara Nucleus Chopper - Left

Description:Nucleus divider with 1.25 mm tip and blade offset at a 60 degree angle is ideal for performing the "Phaco Chop" technique to be used in left hand. Round knurled handle....
Company:Bausch & Lomb Storz

Nagahara Nucleus Chopper - Right

Description:Nucleus divider with 1.25 mm tip and blade offset at a 60 degree angle is ideal for performing the "Phaco Chop" technique. Round knurled handle. Manufactured in titanium....
Company:Bausch & Lomb Storz

Kellan Mini Curved Chopper

Description:Gently curved shaft with blunt angled tip is ideal for chopping the lens during anterior chamber phacoemulsification....
Company:Bausch & Lomb Storz

Osher Lens Chopper

Description:Used when dislocating the lens. Great for chopping during phacoemulsification. Helpful in ushering the IOL out of eye. Useful to reduce possibility of iris tuck with anterior chamber IOL placement....
Company:Bausch & Lomb Storz

Nichamin Double Ended Nucleus Chopper-Spatula

Description:Wedge-shaped chopper designed to allow nucleus chopping in three directions, tip length 1.25 mm. Rounded tip highly polished to protect the posterior capsule. 0.5 mm spatula end is used to manipulate softer nuclei. Round knurled handle....
Company:Bausch & Lomb Storz

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Clinical Data Suggest Decreased Bleeding Risk in People With Severe Hemophilia A While Maintaining Factor VIII Levels Above One Percent

Results Highlighted in Oral Presentation at International Symposiumof Thrombosis and Haemostasis GENEVA, July 10, 2007 /PRNewswire-FirstCall/ -- BaxterHealthcare Corporation today announced the presentation of findingsfrom the ADAPT (Analysis of Data from ADVATE(R) Prospective Trials)study program database showing a statistically significantrelationship between the duration of time spent...

SuperGen to Present at the C.E. Unterberg, Towbin Emerging Growth Opportunities Conference

DUBLIN, Calif., July 06, 2007 /PRNewswire-FirstCall/ --SuperGen, Inc. today announced that Dr. Gregory Berk, Chief MedicalOfficer, will present at the C.E. Unterberg, Towbin Emerging GrowthOpportunities Conference on Thursday, July 12, 2007 at the MandarinOriental Hotel in New York City. SuperGen's presentation at the C.E. Unterberg, Towbin EmergingGrowth Opportunities Conference i...

Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery

Rivaroxaban, a New Oral, Once-Daily Direct Factor Xa Inhibitor,Shows a Significant Reduction in Deep Vein Thrombosis and PulmonaryEmbolism Compared with Enoxaparin with Similarly Low BleedingRates GENEVA, July 8, 2007 - Late-breaking Phase III clinical trialdata presented today at the XXI International Society on Thrombosisand Haemostasis (ISTH) Congress demonstrate that once-daily...

Phase III Trial Results Show Superiority of Rivaroxaban over Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Knee Replacement Surgery

GENEVA--(BUSINESS WIRE)--Jul 8, 2007 - Late-breaking Phase IIIclinical trial data presented today at the XXI InternationalSociety on Thrombosis and Haemostasis (ISTH) Congress demonstratethat once-daily rivaroxaban achieved superior efficacy in theprevention of venous thromboembolism (VTE) in patients undergoingknee replacement surgery in a head-to-head comparison withenoxaparin, the curren...

TMC125 Showed Significant Virologic Response at Week 24 in Treatment-Experienced HIV Patients With NNRTI Resistance in Phase 3 Trials

Data Published in The Lancet on TMC125, an Investigational NNRTIfrom Tibotec YARDLEY, Pa., July 05, 2007 /PRNewswire/ -- Data from twoongoing Phase 3 studies (DUET-1 and DUET-2) showed significantlymore HIV-1 adult patients with documented non-nucleoside reversetranscriptase inhibitor (NNRTI) and protease inhibitor (PI)resistance reached an undetectable viral load (defined as achievingco...

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Personalized medicine

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per at Medicine Dictionary

Temperature measurement

was taken. The average normal body <a href="/ ?q=/ Medicine-Dictionar...

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Superinfection

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