New understanding of DNA repair may pave way to cancer treatments
A Burnham Institute study has found that a protein known for its role in gene regulation has another important function, that of initiating DNA repair. The study, published in the May 27th edition of Molecular Cell, points to new targets for treatment of cancer. Ze'ev Ronai, Ph.D., Director of the Institute's Signal Transduction Program, and his colleagues found that the protein ATF2 ("Ac...Greasing interferon's gears may pave way to greater therapeutic benefits, fewer side effects
nterferon -- a critical protein that mediates the body's defense against a wide variety of infectious agents and tumors -- may soon have greater therapeutic value as the result of a new study by researchers at Washington University School of Medicine in St. Louis. "Essentially, we found a way to grease the gears that drive the interferon signal," says Michael J. Holtzman, M.D., the Selma...Finding paves way for better treatment of autoimmune disease
A signaling molecule with an affinity for alcohol has yielded a rapid, inexpensive way to make large numbers of immune cells that work like beat cops keeping misguided cells from attacking the body. The ability to easily make large numbers of these cells opens the door to improved treatment and a better understanding of autoimmune diseases such as type 1 diabetes and arthritis, Medical Co...Penicillin To Pave Way For New Antibiotics
Newer antibiotics like cephalosporins will replace penicillin and amoxicillin when it comes to treating ailments like strep throat, as they are seen to be more effective. Doctors, who reviewed the treatment given to // 11,426 children, showed that even a short course of the newer drugs is more effective than the traditional 10-day dose of the older antibiotics. Pediatricians at the U...Study Would Pave Way for the Development of New Drugs That Targets TB Proteasome
A new study was conducted to understand the biochemistry and structure of a protein-cleaving complex (proteasome) that is essential to the TB bacterium’s survival. The findings were published in the journal Molecular Microbiology. // The study’s main aim was to design effective treatment for the disease tuberculosis (TB). The study was done by scientists from the U.S. Department of Energy...A protein in the brain paves way for Alzheimer's treatment
Alzheimer's is the most common form of dementia in Canada, affecting some 5% of people over the age of 65. Statistics show that one in four people// over the age of 85 suffer from the disease. According to the study conducted by Dr. Peter St George-Hyslop who is a researcher working on Alzheimer's disease at the University of Toronto it is said that a single chemical in the brain is the c...Treatment of Bacterial Infection Paves the Way to Treat CF Infection
According to the researchers at the Harvard Medical School it is said that a resistant bacteria was found in the lungs of chronically infected cystic fibrosis (CF) patients. // Pseudomonas aeruginosa (PA) is the bacteria which secretes proteins that cause disease in the CF patients says Joseph Mougous, lead author of the study published in the June 9 issue of Science. ‘In the case of Pseu...Dolly Paves the Way for Exhaustive Stem Cell Research
It has been ten years since dolly’s birth and scientist are still doing exhaustive research in the field of stem cells//. Dolly offered hope to millions of sick and disabled people that their disease can be cured. Dolly the Sheep is the world's first clone of an adult mammal. From then on many animals have been cloned and scientific knowledge has advanced and the cloning technique has b...