Critical link in cell death pathway revealed
The role of a protein called XIAP in the regulation of cell death has been identified by Walter and Eliza Hall Institute researchers and has led them to recommend caution when drugs called IAP inhibitors are used to treat cancer patients with underlying liver conditions. A team led by Professor ...Cell Pathway May Be Key to Lung Cancer's Spread
Researchers express hope that finding will lead to treatments,, FRIDAY, July 3 (HealthDay News) -- U.S. researchers say they've found a major cellular flaw that may drive the rapid spread of relapsed lung cancer. When caught early, lung cancer can often be treated. But most cases a...Genetic pathway responsible for link between body clock disturbance and worsening arthritis
Copenhagen, Denmark, Wednesday 10 June 2009: The genes that regulate human circadian rhythm, or 'the body clock', are significantly disturbed in individuals with arthritis, according to the results of a new study presented today at EULAR 2009, the Annual Congress of the European League Against Rhe...U-M researchers link pathway to breast cancer stem cells
ANN ARBOR, Mich. A gene well known to stop or suppress cancer plays a role in cancer stem cells, according to a new study from the University of Michigan Comprehensive Cancer Center. The researchers found that several pathways linked to the gene, called PTEN, also affected the growth of breast ca...Research reveals molecular pathway behind invasive prostate cancers
CINCINNATIUniversity of Cincinnati (UC) cancer and cell biologists have identified a new molecular pathway key to the development of invasive prostate cancers. In a preclinical study led by Maria Diaz-Meco, PhD, the UC team found that simultaneous inactivation of two particular genesknown as...Set out on the Pathway to Change with the Dermatology Nurses' Association
Dermatology Nurses to Convene in Boston, July 31-August 2 BOSTON, May 18 /PRNewswire/ -- Within health care, dermatology nursing professionals play a critical role in providing quality care to their patients. When the Dermatology Nurses' Association (DNA) hosts its Annual Summer Meeting in 2...Semafore Achieves a Preclinical Milestone with SF2626, a PI3K-MEK Dual Pathway Kinase Inhibitor
INDIANAPOLIS, March 17 /PRNewswire/ -- Semafore Pharmaceuticals, Inc. announced today that it has achieved proof of concept in its CRIMP (Control Resulting from Inhibiting Multiple Pathways) kinase platform by designing a small molecule that was demonstrated to inhibit members of both the PI3K (Ph...Roche and FDA Agree on Pathway Towards U.S. Approval of ACTEMRA(R) (tocilizumab)
NUTLEY, N.J., Dec. 4 /PRNewswire/ -- Roche today announced that the U.S. Food and Drug Administration (FDA) has provided further guidance on the requirements for the Biologics License Application (BLA) for ACTEMRA(R) (tocilizumab), the first interleukin-6 (IL-6) receptor-inhibiting monoclonal anti...Progen Terminates PATHWAY Trial & Confirms Focus on Potential High Value Molecules and M&A
BRISBANE, Australia, July 22 /PRNewswire-FirstCall/ -- Following a thorough review that concluded late yesterday, the Board of Progen Pharmaceuticals Limited (ASX: PGL; Nasdaq: PGLA) today announced that it had discontinued the PI-88 phase 3 study in liver cancer. Progen confirmed its strategi...Anesiva Defines Regulatory Pathway for Adlea with FDA
New Phase 3 Plan Could Expedite Clinical Development Pathway SOUTH SAN FRANCISCO, Calif., Oct. 10 /PRNewswire-FirstCall/ -- Anesiva, Inc. (Nasdaq: ANSV ) today announced that it will conduct two Phase 3 clinical trials for the approval of Adlea(TM) -- one of which has already been plann...Prometheus Pathway CTS 2000 Evaluation and Training System
Description: Help restore pelvic muscle function with the Prometheus Pathway CTS 2000 evaluation and training system....AL2500 AirLife™ Prefilled Humidifier Systems
Description:...stems feature a dual-purpose reservoir with a snap-open trigger, which makes a round opening for secure attachment of a humidifier adapter. The oxygen pathway is designed to help prevent particulate from reaching oxygen delivery tubing. An audible relief valve warns if the patient`s tubing becomes occluded. ...Endotrol® Tracheal Tube with Controllable Tip
Description:...g; tracheal tube with directional distal tip control for fast, easy intubation. Indications For Usage: Emergency situations When the intubating pathway is abnormal. Blind nasal intubations. ...UCLA researchers discover new molecular pathway for targeting cancer, disease
A UCLA study has identified a way to turn off a key signaling pathway involved in physiological processes that can also stimulate the development of cancer and other diseases. The findings may lead to new treatments and targeted drugs using this approach. In the study, which is currently ava...Researchers engineer metabolic pathway in mice to prevent diet-induced obesity
In recent years, obesity has taken on epidemic proportions in developed nations, contributing significantly to major medical problems, early death and rising health care costs. According to Centers for Disease Control and Prevention estimates, at least a quarter of all American adults and more tha...ISU researcher identifies genetic pathway responsible for much of plant growth
AMES, Iowa -- Researchers at Iowa State University have discovered a previously unknown pathway in plant cells that regulates plant growth. Yanhai Yin, an assistant professor in genetics, development and cell biology, examined signaling mechanisms of a plant hormone called brassinosteroids. The ...Identification of a key molecular pathway required for brain neural circuit formation
Montral, May 15, 2009 The research group of Dr. Frdric Charron, a researcher at the Institut de recherches cliniques de Montral (IRCM), has made a discovery which could help treat spinal cord injuries and neurodegenerative diseases. This new finding has been published in the current issue of the ...Researchers find pathway and enzyme unique to tularemia organism
San Antonio Researchers are closer to developing therapies to combat the deadly tularemia infection, according to a study published this week in the Proceedings of the National Academy of Sciences ' online Early Edition. Karl Klose, director of the South Texas Center for Emerging Infectious Dis...Tracking the molecular pathway to mixed-lineage leukemia
CAMBRIDGE, Mass. (Dec. 15, 2008) Infants and adults with the blood cancer mixed-lineage leukemia (MLL) typically have a poor prognosis, and most infants die before their first birthdays. Although there are varying causes of MLL, most cases are caused by a fusion of two genes, the MLL and the AF4 ...GeneGo Donates Proprietary Cytokine Pathway Maps to ISICR
ST. JOSEPH, Mich.,. July 21 /PRNewswire/ -- GeneGo, Inc., the leading systems biology tools company, announced today that they have recently donated 41 canonical pathway maps to the International Society for Interferon and Cytokine Research (www.isicr.org). These maps are constructed fro...GEN Reports Growing Focus on PI3-Kinase Pathway in Cancer Research
NEW ROCHELLE, N.Y., Dec. 4 /PRNewswire/ -- Researchers are taking a closer look at the phosphoinositide 3-kinase (PI3-kinase) pathway as studies continue to demonstrate that inhibiting this biological route suppresses tumor growth, reports Genetic Engineering & Biotechnology News (GEN) . The ...Study Suggests GAMMAGARD LIQUID May Target the Primary Pathway Involved in Alzheimer's Disease
Laboratory study shows naturally occurring antibodies contained in GAMMAGARD LIQUID may bind to the primary culprit for Alzheimer's disease CHICAGO, April 15 /PRNewswire-FirstCall/ -- The University of Tennessee Health Science Center and Baxter International Inc. (NYSE: BAX ) today annou...Apoptosis Pathway SpliceArrays from ExonHit Therapeutics Inc.
Description: Alternative Splicing plays an important role in the regulation of signaling pathways involved in apoptosis and cell death. Splice variants have been reported that affect both the activation and inhibition of defined apoptotic pathways. With Apoptosis and Cell Death SpliceArrays you can perform a c...BD Pathway Bioimager from BD Biosciences - Bioimaging
Description: The BD Pathway Bioimager is an automated, confocal, real-time, single cell kinetic and endpoint imaging system that has been integrated into a single, compact unit. The BD Pathway was designed to provide high-resolution, automated confocal imaging with sophisticated imaging software to assist in d...BD Pathway 415 bioimager from BD Biosciences - Bioimaging
Description: For applications not requiring confocal, the BD Pathway 415 is a cost effective alternative to the Pathway 435. And, the Pathway 415 can be field-upgraded to confocal if later applications require it. High-performance, laser-based autofocus is standard. You can elect to use the laser autofocus, ...BD Pathway 435 confocal bioimager from BD Biosciences - Bioimaging
Description: The BD Pathway 435 is an affordable, compact benchtop imager compatible with multiwell plates and slides, providing a broad array of automated imaging capabilities. The system rapidly acquires high-resolution images with high-performance laser autofocus, true confocal optics, flexible computer-cont...Chaps Cell Extract Buffer (10X) from Cell Signaling Technology
Description:...r can be used to lyse cells under nondenaturing conditions and is recommendedfor the preparation of cell lysates to be used with our caspase signaling pathway antibodies...