Should intra-abdominal pressure measurement be a routine for all pancreatitis patients?
Acute pancreatitis remains a disease with an unpredictable clinical course, and significant associated morbidity and mortality. Recently, the elevated intraabdominal pressure (IAP) after onset of acute pancreatitis has gained growing attention, because it is increasingly recognized as an important...Early surgical treatment contributes to better outcomes in gallstone pancreatitis cases
CHICAGO (December 18, 2007) Although delaying surgical treatment remains the standard of care for patients with severe gallstone pancreatitis, a new study published in the December issue of the Journal of the American College of Surgeons shows that, contrary to widespread belief, early cholecyste...Is it pancreatitis in acute abdominal pain in acute viral hepatitis?
Hepatitis viruses have a strong tropism for hepatocytes; viral antigen also has been detected in pancreas and gallbladder. Acute pancreatitis is common in Fulminant hepatic failure but rarely reported in acute viral hepatitis. 124 patients with acute viral hepatitis over a three year period we...Acute pancreatitis and cholangitis: a complication caused by a migrated gastrostomy tube
Percutaneous endoscopic gastrostomy (PEG) is generally considered to be safe with a low rate of serious complications. However, dislocation of a gastrostomy tube can lead to serious complications. The case report article describes a patient who presented to Dr. Imamura of Aichi Medical Univers...Antioxidants offer pain relief in patients with chronic pancreatitis
Bethesda, MD (Jan. 1, 2009) Antioxidant supplementation was found to be effective in relieving pain and reducing levels of oxidative stress in patients with chronic pancreatitis (CP), reports a new study in Gastroenterology . CP is a progressive inflammatory disease of the pancreas in which pati...Baicalin might be a promising therapeutic tool for severe acute pancreatitis
Qingyitang, a representative prescription of Traditional Chinese Medicine for SAP was widely used in the orients countries. But its real pharmacological mechanisms of protective effects on SAP have not been investigated still now. Baicalin, the most effective monomer of Baical skullcap root (an es...Short-term hemofiltration is cost-effective for severe acute pancreatitis
Early nasogastric enteral nutrition is a breakthrough in the management of severe acute pancreatitis. From meta-analysis based on current available clinical studies early nasogastric enteral nutrition appeared effective and safe in clinical practice. Three randomized controlled clinical trials...Risk of Acute Pancreatitis Low With Statins
New research reveals that while cholesterol-lowering drugs do increase the risk of painful inflammation of the pancreas, the side effect is relatively rare//, according to Sonal Singh, M.D., from Wake Forest University School of Medicine, and colleagues. 'Acute pancreatitis is a fairly common co...Indian Scientists Identify Second Pancreatitis Gene
Indian scientists have discovered a second candidate gene - cathepsin B - responsible for the fatal tropical calcific pancreatitis disease that leads to a gradual destruction of the pancreas.// A chronic disease that leads to progressive destruction of pancreas and a painful death, pancreatiti...Acute Pancreatitis On The Rise Due To Alcohol Consumption
Researchers say increasing alcohol consumption may be partly to blame for patients suffering from acute pancreatitis. Acute pancreatitis is mainly caused // by alcohol abuse and gall stones. It produces a sudden attack of severe upper abdominal pain, often accompanied by nausea and vomiting. An att...AMT: Glybera(R) Lowers Pancreatitis Incidence Significantly
AMSTERDAM, The Netherlands, January 28 /PRNewswire-FirstCall/ -- Amsterdam Molecular Therapeutics (Euronext: AMT), a leader in the field of human gene therapy, announced today during the Phacilitate Cell & Gene Therapy Forum new data showing that one treatment of its lead product Glybera(R...Glybera(TM) Shows Long-Term Health Benefits
...th GlyberaTM brings significant and clinically important reduction in acute pancreatitis in lipoprotein lipase deficient patients. Recurrent acute pancreatitis is the most debilitating complication of lipoprotein lipase deficiency (LPL...Research: Popular Diabetes Medications Associated with Increase in Bone Fractures
...uced liver failure. New Findings Contradict pancreatitis Risk from Incretin Mimetics New research sugge...ide and sitagliptin -- do not increase the risk of pancreatitis in patients with diabetes, contradicting previous ...nism of action related to that of exenatide, acute pancreatitis was identify in only 6 patients (0.28 percent). T...ASGE and The Pancreatic Cancer Action Network Partner to Raise Awareness About Pancreatic Cancer
...scientists are currently studying include: diabetes, chronic and hereditary pancreatitis (inflammation of the pancreas), obesity, physical activity, and diet. ...gn diseases such as arthritis (back pain), gallstones (jaundice) or chronic pancreatitis (pain, diarrhea, weight loss). Unfortunately, by the time most patients dev...AMT Intends to Incorporate Additional Data to its Marketing Authorization Dossier for Glybera(R)
...(triglyceride) metabolism, resulting in an almost complete disappearance of pancreatitis during both the immediate 12-week study observation period and the long-ter...gh fat levels in their blood, resulting in recurrent and potentially lethal pancreatitis as well as an increased risk of cardiovascular complications and diabetes. ...AMT Prepares for Submission of Marketing Authorization Dossier for AMT-011 (Glybera(R))
...(HPL) type I, also known as LPL-deficiency. These patients have extremely high fat levels in their blood resulting in recurrent and potentially lethal pancreatitis as well as an increased risk of cardiovascular complications and diabetes. Because of a defective gene HPL-patients do not produce an enzyme that norm...Roche Moves Investigational Diabetes Drug, Taspoglutide, Into Phase III Clinical Trials
... was dose-dependent, transient, mild-to-moderate nausea. No episodes of pancreatitis were reported in this study Safety and Tolerability of High Doses of ...spontaneously while continuing on therapy in most cases. No episodes of pancreatitis were reported in this study About Taspoglutide (R1583) Taspoglutide was...Cellular self-eating promotes pancreatitis
To survive tough times, cells sometimes resort to a form of self-cannibalism called autophagy. But as Hashimoto et al. reveal, autophagy can have a down side, destroying the pancreas by prematurely activating a digestive enzyme. In autophagy, a vesicle swallows a portion of cytoplasm and ferries...Jefferson Department of Surgery announces new pancreas tumor registry
...associated with an increased risk of pancreatic cancer, including familial breast-ovarian cancer, familial melanoma, familial colon cancer, hereditary pancreatitis and Peutz-Jegher's syndrome (a rare hereditary condition that results in gastrointestinal polyps). "While we have not identified a causative gene yet...Baby's genes affect mom's cholesterol levels
...s had almost as much influence as the mother's genes on her lipoprotein levels. Because increased levels of lipoproteins can lead to pre-eclampsia and pancreatitis in pregnant women and also increase their future risk of cardiovascular disease, these findings are of particular interest to the medical community. ...Rare surgery performed to remove pancreas, prevent diabetes
...n the hospital until sometime next week, doctors said. Stewart's chronic pancreatitis developed four years ago as the result of a congenitally malformed pancreat...stents in the pancreatic duct failed to provide relief. The pain of chronic pancreatitis is known to be constant and extremely debilitating. Facing a life of suffer...AMT Starts Preregistration Trial for Glybera(TM)
...Glybera on lipid metabolism and the mechanisms underlying the prevention of pancreatitis attacks. The trial is being performed under a Clinical Trial Application ap...ly significant and clinically important reduction in the incidence of acute pancreatitis in LPLD patients. The longest follow-up of individual patients is well over...Amylin Pharmaceuticals and Eli Lilly Provide Context for FDA Alert for BYETTA
...cing pancreatitis. The companies were aware of the pancreatitis cases referenced in the alert, as well as others, ... a definite causal relationship between BYETTA and pancreatitis has not been proved, to better understand the susp...ther, the characteristics and complications of the pancreatitis cases in patients on BYETTA are consistent with...MannKind Announces Positive Results from a Phase 1a Study of a GLP-1 Formulation
...ate Vice President and Chief Scientific Officer. "As well, with pulsatile delivery, we may potentially avoid unusual adverse effects such as the acute pancreatitis that has been described with presently marketed GLP analogues." "We believe that MKC253 represents a novel approach to the use of GLP-1 as a prandial...